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Searching for up to 100 curated homologs for SM_b21089 FitnessBrowser__Smeli:SM_b21089 (356 a.a.)

Found high-coverage hits (≥70%) to 31 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

acuN / C8YX88 AcuN from Halomonas sp. HTNK1 (see paper)
    40% identity, 72% coverage of query (176 bits)

YfdE / b2371 acetyl-CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yfdE / P76518 acetyl-CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli (strain K12) (see paper)
ACOCT_ECOLI / P76518 Acetyl-CoA:oxalate CoA-transferase; ACOCT; Acetyl-coenzyme A transferase; CoA:oxalate CoA-transferase; EC 2.8.3.19 from Escherichia coli (strain K12) (see 3 papers)
P76518 CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli (see paper)
    34% identity, 87% coverage of query (174 bits)

SUGCT / Q9HAC7 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Homo sapiens (see 3 papers)
Q9HAC7 succinate-hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) from Homo sapiens (see paper)
    33% identity, 81% coverage of query (167 bits)

act / B9U6P4 acyl-CoA:3-sulfinopropionate CoA-transferase from Variovorax paradoxus (see paper)
    33% identity, 82% coverage of query (166 bits)

SUCHY_HUMAN / Q9HAC7 Succinate--hydroxymethylglutarate CoA-transferase; Dermal papilla-derived protein 13; SuccinylCoA:glutarate-CoA transferase; EC 2.8.3.13 from Homo sapiens (Human) (see 3 papers)
    33% identity, 81% coverage of query (166 bits)

ACOCT_ACEAC / A9X6P9 Acetyl-CoA:oxalate CoA-transferase; ACOCT; Acetyl-coenzyme A transferase; CoA:oxalate CoA-transferase; CoAT3; EC 2.8.3.19 from Acetobacter aceti (see paper)
    37% identity, 70% coverage of query (164 bits)

caiB / Q7CXU0 succinate—lglutarate CoA-transferase (EC 2.8.3.13) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
SGCOT_AGRFC / Q7CXU0 Succinate--glutarate CoA-transferase; EC 2.8.3.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
    33% identity, 85% coverage of query (162 bits)

SMTA_CHLAU / Q1KLK1 Succinyl-CoA--L-malate CoA-transferase alpha subunit; EC 2.8.3.22 from Chloroflexus aurantiacus (see paper)
    35% identity, 82% coverage of query (160 bits)

AO356_10845 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Pseudomonas fluorescens FW300-N2C3
    36% identity, 77% coverage of query (159 bits)

mct / Q5V468 succinyl-CoA:mesaconate CoA transferase (EC 2.8.3.26) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see paper)
MCT_HALMA / Q5V468 Succinyl-CoA:mesaconate CoA-transferase; EC 2.8.3.26 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) (see paper)
    34% identity, 81% coverage of query (159 bits)

MCT_HALHT / G0HQ31 Succinyl-CoA:mesaconate CoA-transferase; Mesaconate CoA-transferase; EC 2.8.3.26 from Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755) (see paper)
G0HQ31 succinyl-CoA:mesaconate CoA transferase (EC 2.8.3.26) from Haloarcula hispanica (see paper)
    36% identity, 70% coverage of query (158 bits)

gbuC / A0A415DZ14 γ-butyrobetaine CoA transferase GbuC component from Emergencia timonensis (see paper)
    33% identity, 81% coverage of query (157 bits)

gcdG / Q88RH1 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    35% identity, 79% coverage of query (155 bits)

FDB20_FUSPC / K3VD64 Acyl-CoA transferase FPSE_08120; Fusarium detoxification of benzoxazolinone cluster protein FPSE_08120; FDB cluster protein FPSE_08120; EC 2.8.3.- from Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot fungus) (see 3 papers)
    34% identity, 72% coverage of query (152 bits)

gbuB / A0A415DZ12 γ-butyrobetaine CoA transferase GbuB component from Emergencia timonensis (see paper)
    34% identity, 71% coverage of query (146 bits)

SMTB_CHLAU / Q1KLK0 Succinyl-CoA--L-malate CoA-transferase beta subunit; EC 2.8.3.22 from Chloroflexus aurantiacus (see paper)
    31% identity, 71% coverage of query (141 bits)

A0A1G7S280 formyl-CoA transferase (EC 2.8.3.16) from Pseudomonas abietaniphila (see paper)
    32% identity, 83% coverage of query (133 bits)

Q82M40 formyl-CoA transferase (EC 2.8.3.16) from Streptomyces avermitilis (see paper)
    32% identity, 85% coverage of query (129 bits)

COATR_MYCTU / P96877 Probable fatty acyl-CoA transferase Rv3272; EC 2.8.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    34% identity, 74% coverage of query (123 bits)

Build an alignment

Build an alignment for SM_b21089 and 19 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AMACR / Q9UHK6 α-methylacyl-CoA racemase (EC 5.1.99.4) from Homo sapiens (see 16 papers)
AMACR_HUMAN / Q9UHK6 Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; EC 5.1.99.4 from Homo sapiens (Human) (see 5 papers)
Q9UHK6 alpha-methylacyl-CoA racemase (EC 5.1.99.4) from Homo sapiens (see 9 papers)
    28% identity, 92% coverage of query (116 bits)

IAAL_AROAE / Q5P5Z3 Phenylsuccinyl-CoA transferase; EC 2.8.3.28 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) (see paper)
    33% identity, 72% coverage of query (112 bits)

ptmU4 / D8L2W6 3-amino-2,4-dihydroxybenzoylsulfanide synthase from Streptomyces platensis (see 3 papers)
    30% identity, 77% coverage of query (110 bits)

B3KMU8 alpha-methylacyl-CoA racemase (EC 5.1.99.4) from Homo sapiens (see paper)
    29% identity, 74% coverage of query (110 bits)

CEFD2_HAPCH / Q8J0F0 Isopenicillin N epimerase component 2; IPN epimerase component 2; Isopenicillin N epimerase acyl-CoA racemase component; EC 5.1.1.17; EC 5.1.99.- from Hapsidospora chrysogena (Acremonium chrysogenum) (see paper)
    30% identity, 89% coverage of query (109 bits)

bbsF / Q9KJE9 succinyl-CoA:benzylsuccinate CoA-transferase BbsF subunit (EC 2.8.3.15) from Thauera aromatica (see 2 papers)
BBSF_THAAR / Q9KJE9 Succinyl-CoA:(R)-benzylsuccinate CoA-transferase subunit BbsF; EC 2.8.3.15 from Thauera aromatica (see 2 papers)
    31% identity, 79% coverage of query (94.0 bits)

baiF / P19413 bile acid coenzyme A transferase subunit (EC 2.8.3.25) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 3 papers)
BAIF_CLOSV / P19413 Bile acid CoA-transferase BaiF; Bile acid coenzyme A transferase; Bile acid-inducible operon protein F; Lithocholoyl-CoA:cholate CoA-transferase; EC 2.8.3.25 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 2 papers)
P19413 bile acid CoA-transferase (EC 2.8.3.25) from [Clostridium] scindens (see paper)
    29% identity, 71% coverage of query (90.1 bits)

CAIB_PROSL / Q8GB19 L-carnitine CoA-transferase; Crotonobetainyl-CoA:carnitine CoA-transferase; EC 2.8.3.21 from Proteus sp. (strain LE138) (see paper)
Q8GB19 L-carnitine CoA-transferase (EC 2.8.3.21) from Proteus sp. (see 2 papers)
caiB / CAD48580.1 betainyl-CoA transferase from Proteus sp. LE138 (see paper)
    25% identity, 74% coverage of query (82.8 bits)

baiK / B4YST4 bile acid coenzyme A transferase (EC 2.8.3.25) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
BAIK_CLOSV / B4YST4 Bile acid CoA-transferase BaiK; EC 2.8.3.25 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
    25% identity, 81% coverage of query (81.3 bits)

1xvtA / P31572 Crystal structure of native caib in complex with coenzyme a (see paper)
    27% identity, 74% coverage of query (75.1 bits)

YaaN / b0038 γ-butyrobetainyl-CoA:carnitine CoA transferase (EC 2.8.3.21) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
caiB / P31572 γ-butyrobetainyl-CoA:carnitine CoA transferase (EC 2.8.3.21) from Escherichia coli (strain K12) (see 5 papers)
CAIB_ECOLI / P31572 L-carnitine CoA-transferase; Crotonobetainyl-CoA:carnitine CoA-transferase; EC 2.8.3.21 from Escherichia coli (strain K12) (see 2 papers)
P31572 L-carnitine CoA-transferase (EC 2.8.3.21) from Escherichia coli (see 3 papers)
    27% identity, 74% coverage of query (75.1 bits)

1xvvA Crystal structure of caib mutant d169a in complex with carnitinyl-coa
    27% identity, 74% coverage of query (72.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory