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Searching for up to 100 curated homologs for SM_b21101 FitnessBrowser__Smeli:SM_b21101 (278 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

Removed hits that are identical to the query, leaving 8

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FCNLN_PSEA6 / P0DX22 L-fucono-1,5-lactonase; Fuconolactonase; EC 3.1.1.120 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) (see paper)
    32% identity, 100% coverage of query (125 bits)

BPHYT_RS34220 L-fucono-1,5-lactonase from Burkholderia phytofirmans PsJN
    30% identity, 100% coverage of query (104 bits)

Build an alignment

Build an alignment for SM_b21101 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

clxL / Q0K1W5 2-carboxy-L-lyxonolactone hydrolase from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
    29% identity, 99% coverage of query (85.5 bits)

4dlfA / A0A0H3KNC4 Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group p3221
    29% identity, 99% coverage of query (81.6 bits)

BmulJ_04915 / A0A0H3KNC4 L-fucono-1,5-lactonase (EC 3.1.1.120) from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
FCNLN_BURM1 / A0A0H3KNC4 L-fucono-1,5-lactonase; Fuconolactonase; EC 3.1.1.120 from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
    29% identity, 99% coverage of query (81.3 bits)

LRA2 / Q6BQZ8 L-rhamnono-γ-lactonase (EC 3.1.1.65) from Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (see 3 papers)
    24% identity, 100% coverage of query (73.6 bits)

HSERO_RS05265 L-fucono-1,5-lactonase from Herbaspirillum seropedicae SmR1
    26% identity, 87% coverage of query (62.4 bits)

SLMH_RHIRD / A6XIG7 4-sulfomuconolactone hydrolase; 4-carboxymethylen-4-sulfo-but-2-en-olide hydrolases; EC 3.1.1.92 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) (see paper)
A6XIG7 4-sulfomuconolactone hydrolase (EC 3.1.1.92) from Agrobacterium tumefaciens (see paper)
    25% identity, 84% coverage of query (47.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory