Searching for up to 100 curated homologs for SM_b21221 FitnessBrowser__Smeli:SM_b21221 (412 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 99
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6dtqA / G4XU73 Maltose bound t. Maritima male3 (see paper)
32% identity, 89% coverage of query (174 bits)
TC 3.A.1.1.41 / G4FGN8 Extracellular solute-binding protein family 1, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
32% identity, 89% coverage of query (174 bits)
MALE_THELN / Q7LYW7 Trehalose/maltose-binding protein MalE; TMBP from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 4 papers)
30% identity, 98% coverage of query (146 bits)
TC 3.A.1.1.7 / O51923 MalE aka PF1739, component of Maltose/trehalose porter (see paper)
30% identity, 98% coverage of query (145 bits)
1eu8A / Q7LYW7 Structure of trehalose maltose binding protein from thermococcus litoralis (see paper)
31% identity, 81% coverage of query (145 bits)
Build an alignment for SM_b21221 and 5 homologs with ≥ 30% identity
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smoF / A9CEY9 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol binding protein from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
SMOF_AGRFC / A9CEY9 Sulfoquinovosyl glycerol-binding protein SmoF; SQGro-binding protein SmoF; SQ monooxygenase cluster protein F from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
29% identity, 98% coverage of query (142 bits)
7qhvAAA / A9CEY9 7qhvAAA (see paper)
28% identity, 87% coverage of query (135 bits)
7ofyA Crystal structure of sq binding protein from agrobacterium tumefaciens in complex with sulfoquinovosyl glycerol (sqgro)
28% identity, 87% coverage of query (134 bits)
7yzsAAA Sulfoquinovosyl binding protein
28% identity, 87% coverage of query (133 bits)
5ci5A / A8F7X5 Crystal structure of an abc transporter solute binding protein from thermotoga lettingae tmo (tlet_1705, target efi-510544) bound with alpha-d-tagatose
29% identity, 85% coverage of query (130 bits)
7yzuA Crystal structure of the sulfoquinovosyl binding protein smof complexed with sqme
28% identity, 87% coverage of query (128 bits)
4qrzA / A9CGI0 Crystal structure of sugar transporter atu4361 from agrobacterium fabrum c58, target efi-510558, with bound maltotriose
26% identity, 88% coverage of query (106 bits)
4qsdA Crystal structure of atu4361 sugar transporter from agrobacterium fabrum c58, target efi-510558, with bound sucrose
26% identity, 88% coverage of query (106 bits)
TC 3.A.1.1.19 / Q8L126 PalE, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
palE / BAB96538.1 PalE from Agrobacterium tumefaciens (see 3 papers)
29% identity, 76% coverage of query (105 bits)
Pf1N1B4_5112 sucrose ABC transporter, substrate-binding component from Pseudomonas fluorescens FW300-N1B4
27% identity, 77% coverage of query (105 bits)
SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q7 ThuE aka RB0311 aka SMB20325, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
29% identity, 76% coverage of query (104 bits)
6jb0A Crystal structure of abc transporter alpha-glycoside-binding mutant protein w287a in complex with trehalose
26% identity, 78% coverage of query (102 bits)
TC 3.A.1.1.25 / Q72H68 Trehalose/maltose-binding protein aka TT_C1627, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
26% identity, 78% coverage of query (101 bits)
SM_b21103 ABC transporter for L-Fucose, periplasmic substrate-binding protein from Sinorhizobium meliloti 1021
26% identity, 75% coverage of query (101 bits)
TC 3.A.1.1.12 / Q9AI68 PalE, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
29% identity, 78% coverage of query (101 bits)
6jahA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with glucose
26% identity, 78% coverage of query (101 bits)
6jagA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with sucrose
26% identity, 78% coverage of query (101 bits)
6jadA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with palatinose
26% identity, 78% coverage of query (101 bits)
6j9yA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with maltose
26% identity, 78% coverage of query (101 bits)
TC 3.A.1.1.40 / Q9WZR7 Predicted chitobiose porter. Regulated by chitobiose-responsive regulator ChiR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
27% identity, 89% coverage of query (100 bits)
6jamA / Q5SLD7 Crystal structure of abc transporter alpha-glycoside-binding mutant protein r356a in complex with trehalose (see paper)
26% identity, 78% coverage of query (100 bits)
6jaiA Crystal structure of abc transporter alpha-glycoside-binding mutant protein d118a in complex with maltose
26% identity, 78% coverage of query (98.6 bits)
5ysbA Crystal structure of beta-1,2-glucooligosaccharide binding protein in ligand-free form
24% identity, 91% coverage of query (98.2 bits)
5ysdB / Q92AS8 Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose (see paper)
25% identity, 86% coverage of query (97.8 bits)
Q92AS8 ABC-type beta-glucan transporter (EC 7.5.2.3) from Listeria innocua (see paper)
25% identity, 89% coverage of query (97.8 bits)
5ysdA Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose
24% identity, 91% coverage of query (97.8 bits)
8artB / C9ZHD5 Abc transporter binding protein male from streptomyces scabiei in complex with maltose
29% identity, 88% coverage of query (97.4 bits)
TC 3.A.1.1.44 / Q7AKP1 Putative maltose-binding protein, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
29% identity, 88% coverage of query (94.7 bits)
5iaiA / B9JM84 Crystal structure of abc transporter solute binding protein arad_9887 from agrobacterium radiobacter k84, target efi-510945 in complex with ribitol
26% identity, 85% coverage of query (89.0 bits)
4ryaA / B9JRF8 Crystal structure of abc transporter solute binding protein avi_3567 from agrobacterium vitis s4, target efi-510645, with bound d-mannitol
27% identity, 88% coverage of query (88.6 bits)
3jzjA / B0B0V1 Crystal structures of the gach receptor of streptomyces glaucescens gla.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of salmonella typhimurium. (see paper)
26% identity, 88% coverage of query (87.4 bits)
3k02A Crystal structures of the gach receptor of streptomyces glaucescens gla.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of salmonella typhimurium.
26% identity, 88% coverage of query (87.4 bits)
Dshi_0547 ABC transporter for Xylitol, periplasmic substrate-binding component from Dinoroseobacter shibae DFL-12
25% identity, 97% coverage of query (84.7 bits)
LPQY_MYCT3 / G7CES0 Trehalose-binding lipoprotein LpqY; Extracellular solute-binding protein; SugABC transporter substrate-binding protein LpqY; SugABC transporter SBP LpqY from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
23% identity, 80% coverage of query (83.2 bits)
7apeA / G7CES0 Crystal structure of lpqy from mycobacterium thermoresistible in complex with trehalose (see paper)
23% identity, 80% coverage of query (82.8 bits)
7x0lA / A3DE73 Crystal structure of sugar binding protein cbpb complexed wtih cellotetraose from clostridium thermocellum (see paper)
25% identity, 78% coverage of query (80.9 bits)
Ac3H11_2944 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Acidovorax sp. GW101-3H11
25% identity, 93% coverage of query (80.9 bits)
TC 3.A.1.1.5 / O30831 SmoE, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
25% identity, 95% coverage of query (80.5 bits)
lpqY / P9WGU9 trehalose-binding lipoprotein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
LPQY_MYCTU / P9WGU9 Trehalose-binding lipoprotein LpqY; SugABC transporter substrate-binding protein LpqY; SugABC transporter SBP LpqY from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / Q7D8J9 PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
24% identity, 79% coverage of query (79.3 bits)
8jabA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-06
24% identity, 79% coverage of query (79.3 bits)
8jadA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-17
24% identity, 79% coverage of query (79.3 bits)
8jacA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-16
24% identity, 79% coverage of query (79.3 bits)
8ja9A Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-03
24% identity, 79% coverage of query (79.3 bits)
8ja7E / P9WGU9 Cryo-em structure of mycobacterium tuberculosis lpqy-sugabc in complex with trehalose
24% identity, 79% coverage of query (79.0 bits)
5f7vA / Q8YAE9 Abc substrate-binding protein lmo0181 from listeria monocytogenes in complex with cycloalternan (see paper)
24% identity, 88% coverage of query (78.6 bits)
7cafE / A0R2C3 Mycobacterium smegmatis lpqy-sugabc complex in the pre-translocation state (see paper)
25% identity, 75% coverage of query (77.4 bits)
mtlE / Q4KC57 polyol ABC-type transporter periplasmic substrate-binding protein from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
24% identity, 94% coverage of query (75.9 bits)
TC 3.A.1.1.21 / Q9L027 BxlE, component of The xylobiose porter; BxlEFG(K) from Streptomyces coelicolor (see paper)
26% identity, 75% coverage of query (72.0 bits)
BPHYT_RS16115 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
23% identity, 88% coverage of query (72.0 bits)
PGA1_c13210 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Phaeobacter inhibens BS107
24% identity, 79% coverage of query (71.2 bits)
TC 3.A.1.1.22 / Q9X0T1 MalE1; aka Maltose ABC transporter, periplasmic maltose-binding protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
23% identity, 87% coverage of query (70.9 bits)
6dtuA / Q9X0T1 Maltotetraose bound t. Maritima male1 (see paper)
23% identity, 87% coverage of query (70.9 bits)
4r9gA Cpmnbp1 with mannotriose bound
24% identity, 88% coverage of query (69.7 bits)
7bvtA / D2YYD8 Crystal structure of cyclic alpha-maltosyl-1,6-maltose binding protein from arthrobacter globiformis (see paper)
24% identity, 88% coverage of query (68.2 bits)
PS417_12715 ABC transporter for D-Mannitol and D-Sorbitol, periplasmic substrate-binding protein from Pseudomonas simiae WCS417
24% identity, 97% coverage of query (67.4 bits)
MANBP_PSEAE / Q9I1E0 Mannitol-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
24% identity, 89% coverage of query (67.4 bits)
TC 3.A.1.1.16 / P58300 MalE aka PF1938, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus (see paper)
22% identity, 86% coverage of query (67.0 bits)
AO356_00025 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
23% identity, 97% coverage of query (67.0 bits)
Pf6N2E2_1963 ABC transporter for D-sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
22% identity, 97% coverage of query (67.0 bits)
1eljA / P58300 The crystal structure of liganded maltodextrin-binding protein from pyrococcus furiosus (see paper)
22% identity, 86% coverage of query (67.0 bits)
TC 3.A.1.1.49 / O30491 MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
25% identity, 80% coverage of query (65.9 bits)
6dtsA / Q9S5Y1 Maltotetraose bound t. Maritima male2 (see paper)
24% identity, 86% coverage of query (63.9 bits)
4r9fA / L0E2M2 Cpmnbp1 with mannobiose bound (see paper)
24% identity, 88% coverage of query (63.9 bits)
TC 3.A.1.1.22 / Q9S5Y1 MalE2; aka Maltose ABC transporter, periplasmic maltose-binding protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
24% identity, 86% coverage of query (63.5 bits)
4g68A / J9PBT4 Biochemical and structural insights into xylan utilization by the thermophilic bacteriumcaldanaerobius polysaccharolyticus (see paper)
24% identity, 78% coverage of query (63.5 bits)
2i58A Crystal structure of rafe from streptococcus pneumoniae complexed with raffinose
25% identity, 75% coverage of query (63.2 bits)
6preA / A0A0H2URJ7 Sbp rafe in complex with verbascose (see paper)
25% identity, 75% coverage of query (62.8 bits)
6rjyA / B3EYM9 The crystal structure of abne, an arabino-oligosaccharide binding protein, in complex with arabinobiose (see paper)
25% identity, 92% coverage of query (62.4 bits)
6lceA / A0A0A1GL90 Crystal structure of beta-l-arabinobiose binding protein - selenomethionine derivative (see paper)
25% identity, 71% coverage of query (62.4 bits)
4wmwA The structure of mbp-mcl1 bound to ligand 5 at 1.9a
25% identity, 86% coverage of query (60.8 bits)
4wmvA Structure of mbp-mcl1 bound to ligand 4 at 2.4a
25% identity, 86% coverage of query (60.8 bits)
2vgqA / P0AEX9,Q7Z434 Crystal structure of human ips-1 card (see paper)
25% identity, 86% coverage of query (60.1 bits)
4wgiA A single diastereomer of a macrolactam core binds specifically to myeloid cell leukemia 1 (mcl1)
25% identity, 86% coverage of query (60.1 bits)
6qgdA Structure of human mcl-1 in complex with thienopyrimidine inhibitor
24% identity, 86% coverage of query (59.3 bits)
7c6gA / Q53W80 Crystal structure of beta-glycosides-binding protein (w177x) of abc transporter in an open-liganded state bound to gentiobiose (see paper)
22% identity, 80% coverage of query (58.9 bits)
7c6iB Crystal structure of beta-glycosides-binding protein (w177x) of abc transporter in an open-liganded state bound to sophorose
22% identity, 80% coverage of query (58.9 bits)
6yblA Structure of mbp-mcl-1 in complex with compound 9m
24% identity, 86% coverage of query (58.9 bits)
6qylA Structure of mbp-mcl-1 in complex with compound 8a
24% identity, 86% coverage of query (58.9 bits)
6qxjA Structure of mbp-mcl-1 in complex with compound 6a
24% identity, 86% coverage of query (58.9 bits)
7c6lA Crystal structure of beta-glycosides-binding protein (w177x) of abc transporter in a closed state bound to cellotriose (form ii)
22% identity, 79% coverage of query (58.5 bits)
7c6jB Crystal structure of beta-glycosides-binding protein (w177x) of abc transporter in a closed state bound to cellobiose
22% identity, 79% coverage of query (58.5 bits)
7uajB / P03126,P0AEX9 Crystal structure of apo hpv16 e6
25% identity, 86% coverage of query (58.2 bits)
3a3cA / P0AEX9,P36046 Crystal structure of tim40/mia40 fusing mbp, c296s and c298s mutant (see paper)
25% identity, 86% coverage of query (58.2 bits)
7c6kA Crystal structure of beta-glycosides-binding protein (w177x) of abc transporter in a closed state bound to cellotriose (form i)
22% identity, 79% coverage of query (58.2 bits)
4my2A / P0AEX9,Q00604 Crystal structure of norrin in fusion with maltose binding protein (see paper)
25% identity, 86% coverage of query (57.8 bits)
5jonA / O88703,P0AEY0 Crystal structure of the unliganded form of hcn2 cnbd (see paper)
25% identity, 86% coverage of query (57.8 bits)
4nufA / P0AEX9,Q62227 Crystal structure of shp/eid1 (see paper)
25% identity, 86% coverage of query (57.8 bits)
4xajB / P0AEX9,Q9Y466 Crystal structure of human nr2e1/tlx (see paper)
25% identity, 86% coverage of query (57.8 bits)
4wviA / P0AEX9,Q5HHB9 Crystal structure of the type-i signal peptidase from staphylococcus aureus (spsb) in complex with a substrate peptide (pep2). (see paper)
26% identity, 86% coverage of query (57.8 bits)
6wh0A / A7LM80,C3SHQ8 Crystal structure of hybcl-2-4 with hybax bh3 (see paper)
25% identity, 86% coverage of query (57.8 bits)
1zjlA Crystal structure of zinc-bound engineered maltose binding protein
25% identity, 85% coverage of query (57.8 bits)
4xajC Crystal structure of human nr2e1/tlx
25% identity, 86% coverage of query (57.8 bits)
4xaiA / P0AEY0,Q9NCL0 Crystal structure of red flour beetle nr2e1/tlx (see paper)
25% identity, 86% coverage of query (57.4 bits)
5cfvA / P0AEX9 Fusion of maltose-binding protein and pila from acinetobacter nosocomialis m2 (see paper)
25% identity, 86% coverage of query (57.4 bits)
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Lawrence Berkeley National Laboratory