Sites on a Tree

 

Searching for up to 100 curated homologs for SM_b21301 SM_b21301 ly membrane-anchored aldehyde dehydrogenase (794 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BPHYT_RS25810 acetaldehyde dehydrogenase (EC 1.2.1.3) from Burkholderia phytofirmans PsJN
    69% identity, 100% coverage of query (1050 bits)

H281DRAFT_01117 acetaldehyde dehydrogenase (EC 1.2.1.3) from Paraburkholderia bryophila 376MFSha3.1
    68% identity, 100% coverage of query (1036 bits)

6mvtA Structure of a bacterial aldh16 complexed with nadh
    59% identity, 98% coverage of query (873 bits)

6mvsA Structure of a bacterial aldh16 complexed with NAD
    59% identity, 98% coverage of query (873 bits)

6mvuA / A0A0Q3EUQ3 Structure of a bacterial aldh16 active site mutant c295a complexed with p-nitrophenylacetate (see paper)
    59% identity, 98% coverage of query (868 bits)

A16A1_HUMAN / Q8IZ83 Aldehyde dehydrogenase family 16 member A1 from Homo sapiens (Human) (see paper)
Q8IZ83 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see paper)
    39% identity, 99% coverage of query (459 bits)

Build an alignment

Build an alignment for SM_b21301 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory