Searching for up to 100 curated homologs for SMa0527 FitnessBrowser__Smeli:SMa0527 (199 a.a.)
Found high-coverage hits (≥70%) to 80 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YtjC / b4395 putative phosphatase from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gpmB / RF|NP_418812 PGAM from Escherichia coli K12 (see paper)
38% identity, 80% coverage of query (94.0 bits)
cobC / D1BMI5 adenosylcobamide phosphatase (EC 3.1.3.73) from Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3) (see paper)
34% identity, 80% coverage of query (88.2 bits)
PhpB / b0638 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
cobC / P52086 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli (strain K12) (see 2 papers)
36% identity, 80% coverage of query (84.0 bits)
cobC / P39701 adenosylcobalamin/α-ribazole phosphatase (EC 3.1.3.73) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
COBC_SALTY / P39701 Adenosylcobalamin/alpha-ribazole phosphatase; Adenosylcobalamin phosphatase; Alpha-ribazole-5'-phosphate phosphatase; EC 3.1.3.73 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
P39701 adenosylcobalamin/alpha-ribazole phosphatase (EC 3.1.3.73) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
cobC / RF|NP_459635.1 alpha-ribazole phosphatase; EC 3.1.3.73 from Salmonella typhimurium LT2 (see 2 papers)
35% identity, 79% coverage of query (78.6 bits)
SERCL_ARATH / F4KI56 Metal-independent phosphoserine phosphatase; iPSP; Phosphoglycerate mutase-like protein 3; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 76% coverage of query (77.8 bits)
Build an alignment for SMa0527 and 5 homologs with ≥ 30% identity
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PHOE_BACSU / O07617 Uncharacterized phosphatase PhoE; EC 3.1.3.- from Bacillus subtilis (strain 168) (see 2 papers)
29% identity, 95% coverage of query (73.9 bits)
1h2eA / Q9ALU0 Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
31% identity, 96% coverage of query (72.8 bits)
1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate
31% identity, 96% coverage of query (72.8 bits)
CA1P_WHEAT / W5EP13 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Triticum aestivum (Wheat) (see paper)
30% identity, 97% coverage of query (68.2 bits)
PSPB_HYDTT / D3DFP8 Putative phosphoserine phosphatase 2; PSP 2; PSPase 2; Metal-independent phosphoserine phosphatase 2; iPSP2; O-phosphoserine phosphohydrolase 2; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFP8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see paper)
29% identity, 79% coverage of query (67.8 bits)
6m1xC Crystal structure of phosphoserine phosphatase in complex with 3- phosphoglyceric acid from entamoeba histolytica
28% identity, 94% coverage of query (65.1 bits)
PSPA_HYDTT / D3DFG8 Phosphoserine phosphatase 1; PSP 1; PSPase 1; Metal-independent phosphoserine phosphatase 1; iPSP1; O-phosphoserine phosphohydrolase 1; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFG8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see 3 papers)
30% identity, 87% coverage of query (62.4 bits)
CA1P_ARATH / Q9FNJ9 Probable 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
29% identity, 97% coverage of query (62.4 bits)
A7UAK5 6-phosphofructo-2-kinase (EC 2.7.1.105) from Mus musculus (see 2 papers)
34% identity, 78% coverage of query (62.0 bits)
Q7TS91 6-phosphofructo-2-kinase (EC 2.7.1.105) from Mus musculus (see paper)
34% identity, 78% coverage of query (62.0 bits)
1k6mA / P16118 Crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (see paper)
34% identity, 78% coverage of query (61.6 bits)
Q3U3S6 fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Mus musculus (see paper)
35% identity, 77% coverage of query (61.6 bits)
A7UAK4 6-phosphofructo-2-kinase (EC 2.7.1.105) from Mus musculus (see paper)
33% identity, 91% coverage of query (61.2 bits)
1tipA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
32% identity, 95% coverage of query (61.2 bits)
1c81A Michaelis complex of fructose-2,6-bisphosphatase
32% identity, 95% coverage of query (61.2 bits)
1c80A Regulatory complex of fructose-2,6-bisphosphatase
32% identity, 95% coverage of query (61.2 bits)
1c7zA Regulatory complex of fructose-2,6-bisphosphatase
32% identity, 95% coverage of query (61.2 bits)
Q2YJN6 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Brucella abortus (see paper)
31% identity, 82% coverage of query (60.8 bits)
O35552 fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see paper)
34% identity, 78% coverage of query (60.8 bits)
5zr2C / N9V397 Crystal structure of phosphoserine phosphatase mutant (h9a) from entamoeba histolytica in complex with phosphoserine (see paper)
28% identity, 94% coverage of query (60.8 bits)
PFKFB2 / O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 7 papers)
F262_HUMAN / O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
O60825 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 7 papers)
34% identity, 77% coverage of query (60.5 bits)
A7UAK3 6-phosphofructo-2-kinase (EC 2.7.1.105) from Rattus norvegicus (see paper)
32% identity, 91% coverage of query (60.1 bits)
5htkA / O60825 Human heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2) (see paper)
34% identity, 78% coverage of query (60.1 bits)
Q9ESY2 fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Mus musculus (see paper)
34% identity, 77% coverage of query (59.7 bits)
PFKFB3 / Q16875 Fructose-2,6-bisphosphatase (EC 2.7.1.105; EC 3.1.3.46) from Homo sapiens (see 9 papers)
F263_HUMAN / Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 5 papers)
Q16875 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 21 papers)
32% identity, 93% coverage of query (59.3 bits)
2axnA / Q16875 Crystal structure of the human inducible form 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase (see paper)
31% identity, 96% coverage of query (59.3 bits)
P49872 fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Bos taurus (see paper)
35% identity, 78% coverage of query (59.3 bits)
F261_RAT / P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
P07953 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see 4 papers)
32% identity, 96% coverage of query (59.3 bits)
5ak0A Human pfkfb3 in complex with an indole inhibitor 6
31% identity, 96% coverage of query (59.3 bits)
4d4lA Human pfkfb3 in complex with a pyrrolopyrimidone compound
31% identity, 96% coverage of query (59.3 bits)
4d4jA Human pfkfb3 in complex with a pyrrolopyrimidone compound
31% identity, 96% coverage of query (59.3 bits)
5ajxA Human pfkfb3 in complex with an indole inhibitor 3
31% identity, 96% coverage of query (59.3 bits)
6hviA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 2
31% identity, 96% coverage of query (59.3 bits)
5ajwA Human pfkfb3 in complex with an indole inhibitor 2
31% identity, 96% coverage of query (59.3 bits)
4ma4A S-glutathionylated pfkfb3
32% identity, 95% coverage of query (59.3 bits)
4d4kA Human pfkfb3 in complex with a pyrrolopyrimidone compound
31% identity, 96% coverage of query (59.3 bits)
5ajyA Human pfkfb3 in complex with an indole inhibitor 4
31% identity, 96% coverage of query (59.3 bits)
4d4mA Human pfkfb3 in complex with a pyrrolopyrimidone compound
31% identity, 96% coverage of query (59.3 bits)
3qpwA Pfkfb3 in complex with aluminum tetrafluoride
31% identity, 96% coverage of query (59.3 bits)
5ajvB Human pfkfb3 in complex with an indole inhibitor 1
31% identity, 96% coverage of query (59.3 bits)
1fbtA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
32% identity, 94% coverage of query (59.3 bits)
2i1vB Crystal structure of pfkfb3 in complex with adp and fructose-2,6- bisphosphate
31% identity, 96% coverage of query (59.3 bits)
2dwoA Pfkfb3 in complex with adp and pep
31% identity, 96% coverage of query (59.3 bits)
6etjA Human pfkfb3 in complex with kan0438241
31% identity, 96% coverage of query (59.3 bits)
5ajzA Human pfkfb3 in complex with an indole inhibitor 5
31% identity, 96% coverage of query (58.9 bits)
6ic0A Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 4
31% identity, 96% coverage of query (58.9 bits)
6ibyA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 6
31% identity, 96% coverage of query (58.9 bits)
2dwpA A pseudo substrate complex of 6-phosphofructo-2-kinase of pfkfb
32% identity, 95% coverage of query (58.9 bits)
6hvjA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 3
31% identity, 96% coverage of query (58.9 bits)
3qpuA Pfkfb3 in complex with ppi
31% identity, 96% coverage of query (58.9 bits)
6ibzA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 7
31% identity, 96% coverage of query (58.9 bits)
6ibxA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 5
31% identity, 96% coverage of query (58.9 bits)
6hvhA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 1
31% identity, 96% coverage of query (58.9 bits)
PFKFB1 / P16118 Fructose-2,6-bisphosphatase (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 7 papers)
F261_HUMAN / P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
P16118 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 5 papers)
34% identity, 78% coverage of query (58.5 bits)
PMGY_SCHPO / P36623 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
gpm1 / RF|NP_594889.1 monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1; EC 5.4.2.1 from Schizosaccharomyces pombe (see paper)
29% identity, 81% coverage of query (58.5 bits)
4ij6A / D3DFG8 Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
30% identity, 87% coverage of query (58.2 bits)
YO283_YEAST / Q12040 Broad-specificity phosphatase YOR283W; EC 3.1.3.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
29% identity, 86% coverage of query (58.2 bits)
Q5U4Z6 6-phosphofructo-2-kinase (EC 2.7.1.105) from Xenopus laevis (see paper)
33% identity, 78% coverage of query (56.2 bits)
P70265 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Mus musculus (see 3 papers)
33% identity, 78% coverage of query (55.8 bits)
F262_BOVIN / P26285 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Bos taurus (Bovine) (see paper)
P26285 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Bos taurus (see 2 papers)
33% identity, 78% coverage of query (55.8 bits)
PFKFB4 / Q16877 Fructose-2,6-bisphosphatase (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 6 papers)
Q16877 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 9 papers)
33% identity, 78% coverage of query (55.8 bits)
5hr5A Bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2)
33% identity, 78% coverage of query (55.5 bits)
Q9JJH5 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see 3 papers)
33% identity, 77% coverage of query (55.1 bits)
1bifA / P25114 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional enzyme complexed with atp-g-s and phosphate (see paper)
32% identity, 78% coverage of query (55.1 bits)
YFFL_SCHPO / O94461 Probable phosphatase C1687.21; EC 3.1.3.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 75% coverage of query (54.7 bits)
SUGPH_MYCTU / Q6MWZ7 Acid phosphatase; Broad-specificity phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.2; EC 3.1.3.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
28% identity, 79% coverage of query (54.3 bits)
hbrB protein involved in hyphal growth and polarity from Emericella nidulans (see paper)
30% identity, 79% coverage of query (50.1 bits)
TIGAR / Q9NQ88 fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) from Homo sapiens (see 2 papers)
TIGAR_HUMAN / Q9NQ88 Fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; EC 3.1.3.46 from Homo sapiens (Human) (see 10 papers)
26% identity, 93% coverage of query (47.8 bits)
Gpm / b0755 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gpmA / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli (strain K12) (see 20 papers)
GPMA_ECOLI / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Escherichia coli (strain K12) (see 4 papers)
gpmA / PDB|1E58_A 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; EC 5.4.2.1 from Shigella flexneri (see 12 papers)
26% identity, 83% coverage of query (46.6 bits)
1e59A / P62707 E.Coli cofactor-dependent phosphoglycerate mutase complexed with vanadate (see paper)
26% identity, 83% coverage of query (46.6 bits)
GPMA_MYCTU / P9WIC9 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
26% identity, 90% coverage of query (46.2 bits)
GPMA_STRP6 / Q5XB88 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
27% identity, 89% coverage of query (46.2 bits)
SHB17_YEAST / P36136 Sedoheptulose 1,7-bisphosphatase; EC 3.1.3.37 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P36136 fructose-bisphosphatase (EC 3.1.3.11) from Saccharomyces cerevisiae (see paper)
22% identity, 97% coverage of query (45.8 bits)
3lg2A / P36136 A ykr043c/ fructose-1,6-bisphosphate product complex following ligand soaking (see paper)
22% identity, 97% coverage of query (45.4 bits)
mas1' / Q7BLR9 mannopine synthase from Rhizobium radiobacter (see 3 papers)
31% identity, 77% coverage of query (44.7 bits)
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