Searching for up to 100 curated homologs for SMa1410 FitnessBrowser__Smeli:SMa1410 (277 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
38% identity, 94% coverage of query (185 bits)
E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
37% identity, 90% coverage of query (162 bits)
GALUR / O49133 D-galacturonate reductase (EC 1.1.1.365) from Fragaria ananassa (see 2 papers)
GALUR_FRAAN / O49133 D-galacturonate reductase; FaGalUR; Aldo-keto reductase 2; EC 1.1.1.365 from Fragaria ananassa (Strawberry) (Fragaria chiloensis x Fragaria virginiana) (see 2 papers)
O49133 D-galacturonate reductase (EC 1.1.1.365) from Fragaria x ananassa (see paper)
36% identity, 86% coverage of query (154 bits)
BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
35% identity, 91% coverage of query (154 bits)
Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
37% identity, 87% coverage of query (153 bits)
Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
37% identity, 87% coverage of query (153 bits)
1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
34% identity, 88% coverage of query (152 bits)
PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
34% identity, 88% coverage of query (152 bits)
3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
37% identity, 87% coverage of query (152 bits)
yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
37% identity, 87% coverage of query (152 bits)
A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
34% identity, 89% coverage of query (150 bits)
PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
34% identity, 90% coverage of query (149 bits)
4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
34% identity, 90% coverage of query (149 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
35% identity, 88% coverage of query (149 bits)
Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
33% identity, 89% coverage of query (146 bits)
2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
33% identity, 89% coverage of query (146 bits)
4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
33% identity, 88% coverage of query (146 bits)
Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
33% identity, 88% coverage of query (146 bits)
4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
33% identity, 88% coverage of query (146 bits)
akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
35% identity, 87% coverage of query (141 bits)
Q2TJA5 prostaglandin-F synthase (EC 1.1.1.188) from Sus scrofa (see paper)
33% identity, 93% coverage of query (140 bits)
YER5_SCHPO / O14088 Uncharacterized oxidoreductase C2F3.05c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 88% coverage of query (138 bits)
1m9hA Corynebacterium 2,5-dkgr a and phe 22 replaced with tyr (f22y), lys 232 replaced with gly (k232g), arg 238 replaced with his (r238h)and ala 272 replaced with gly (a272g)in presence of nadh cofactor
35% identity, 88% coverage of query (138 bits)
DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
34% identity, 88% coverage of query (137 bits)
Build an alignment for SMa1410 and 24 homologs with ≥ 30% identity
Or download the sequences
AK1A1_RAT / P51635 Aldo-keto reductase family 1 member A1; 3-DG-reducing enzyme; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Rattus norvegicus (Rat) (see 4 papers)
P51635 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Rattus norvegicus (see 2 papers)
29% identity, 90% coverage of query (136 bits)
dkgA / P06632 2,5-diketo-D-gluconate reductase A monomer (EC 1.1.1.346) from Corynebacterium sp. (strain ATCC 31090) (see 4 papers)
DKGA_CORSC / P06632 2,5-diketo-D-gluconic acid reductase A; 2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; EC 1.1.1.346 from Corynebacterium sp. (strain ATCC 31090) (see 2 papers)
P06632 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Corynebacterium sp. (see paper)
35% identity, 88% coverage of query (136 bits)
1a80A / P06632 Native 2,5-diketo-d-gluconic acid reductase a from corynbacterium sp. Complexed with NADPH (see paper)
35% identity, 88% coverage of query (136 bits)
5uxfA Crystal structure of mouse recon (akr1c13) in complex with cyclic di- amp
33% identity, 94% coverage of query (136 bits)
5jh2A / A2T1W7 Crystal structure of the holo form of akr4c7 from maize (see paper)
32% identity, 85% coverage of query (135 bits)
3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
30% identity, 93% coverage of query (135 bits)
Q8VCX1 DELTA4-3-oxosteroid 5beta-reductase (EC 1.3.1.3) from Mus musculus (see 2 papers)
33% identity, 87% coverage of query (134 bits)
AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
29% identity, 90% coverage of query (134 bits)
3cv7A Crystal structure of porcine aldehyde reductase ternary complex
29% identity, 90% coverage of query (134 bits)
D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
30% identity, 94% coverage of query (133 bits)
AKR1C4 / P17516 aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.357) from Homo sapiens (see 9 papers)
AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human) (see 11 papers)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens (see 4 papers)
30% identity, 94% coverage of query (133 bits)
Q5FYA7 prostaglandin-F synthase (EC 1.1.1.188) from Canis lupus familiaris (see 2 papers)
31% identity, 94% coverage of query (133 bits)
Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
29% identity, 90% coverage of query (133 bits)
2fvlA / P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (akr1c4) complexed with NADP+
30% identity, 94% coverage of query (132 bits)
AK1CA_RAT / D3ZF77 Aldo-keto reductase family 1 member C15; RAKc; EC 1.1.1.-; EC 1.1.1.216 from Rattus norvegicus (Rat) (see 4 papers)
32% identity, 94% coverage of query (132 bits)
A2T1W7 aldose reductase (EC 1.1.1.21) from Zea mays (see 2 papers)
31% identity, 85% coverage of query (132 bits)
AK1A1_HUMAN / P14550 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Homo sapiens (Human) (see 4 papers)
29% identity, 90% coverage of query (132 bits)
Akr1d1 / P31210 Δ4-3-oxosteroid 5β-reductase (EC 1.3.1.3) from Rattus norvegicus (see paper)
32% identity, 92% coverage of query (131 bits)
AKR_SYNY3 / P74308 Aldo/keto reductase slr0942; AKR; AKR3G1; EC 1.1.1.184 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
32% identity, 89% coverage of query (131 bits)
1vp5A / Q9X0A2 Crystal structure of 2,5-diketo-d-gluconic acid reductase (tm1009) from thermotoga maritima at 2.40 a resolution
31% identity, 87% coverage of query (131 bits)
6m7kA Structure of mouse recon (akr1c13) in complex with cyclic amp-amp-gmp (caag)
32% identity, 94% coverage of query (131 bits)
AKR4C8 / O80944 aldo-keto reductase family 4 member C8 (EC 1.1.1.21; EC 1.1.1.210) from Arabidopsis thaliana (see paper)
AKRC8_ARATH / O80944 Aldo-keto reductase family 4 member C8; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 85% coverage of query (130 bits)
3h7rA / O80944 Crystal structure of the plant stress-response enzyme akr4c8 (see paper)
30% identity, 85% coverage of query (130 bits)
DKGB_CORSS / P15339 2,5-diketo-D-gluconic acid reductase B; 2,5-DKG reductase B; 2,5-DKGR B; 25DKGR-B; AKR5D; EC 1.1.1.274 from Corynebacterium sp. (strain SHS752001) (see paper)
34% identity, 87% coverage of query (130 bits)
3ln3A / Q8VC28 Crystal structure of putative reductase (np_038806.2) from mus musculus at 1.18 a resolution
32% identity, 94% coverage of query (130 bits)
H9CWC0 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) (EC 1.1.1.274) from Corynebacterium glutamicum (see paper)
33% identity, 88% coverage of query (130 bits)
3uzxB Crystal structure of 5beta-reductase (akr1d1) e120h mutant in complex with NADP+ and epiandrosterone
32% identity, 91% coverage of query (130 bits)
3uzxA Crystal structure of 5beta-reductase (akr1d1) e120h mutant in complex with NADP+ and epiandrosterone
32% identity, 91% coverage of query (130 bits)
Q8VC28 Aldo-keto reductase family 1 member C13; EC 1.1.1.- from Mus musculus (Mouse)
32% identity, 94% coverage of query (130 bits)
3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
31% identity, 94% coverage of query (129 bits)
AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
31% identity, 94% coverage of query (128 bits)
DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
30% identity, 94% coverage of query (128 bits)
3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
31% identity, 94% coverage of query (128 bits)
6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
31% identity, 94% coverage of query (128 bits)
6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
31% identity, 94% coverage of query (128 bits)
4yvpA Crystal structure of akr1c1 complexed with glibenclamide
31% identity, 94% coverage of query (128 bits)
3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
31% identity, 94% coverage of query (128 bits)
AK1D1_HUMAN / P51857 Aldo-keto reductase family 1 member D1; 3-oxo-5-beta-steroid 4-dehydrogenase; Delta(4)-3-ketosteroid 5-beta-reductase; Delta(4)-3-oxosteroid 5-beta-reductase; EC 1.3.1.3 from Homo sapiens (Human) (see 8 papers)
P51857 DELTA4-3-oxosteroid 5beta-reductase (EC 1.3.1.3) from Homo sapiens (see 8 papers)
32% identity, 91% coverage of query (127 bits)
3burA / P51857 Crystal structure of delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and testosterone. Resolution: 1.62 a. (see paper)
32% identity, 91% coverage of query (127 bits)
3g1rB Crystal structure of human liver 5beta-reductase (akr1d1) in complex with NADP and finasteride. Resolution 1.70 a
32% identity, 91% coverage of query (127 bits)
3dopB Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 5beta-dihydrotestosterone, resolution 2.00a
32% identity, 91% coverage of query (127 bits)
3cotA Crystal structure of human liver delta(4)-3-ketosteroid 5beta- reductase (akr1d1) in complex with progesterone and NADP. Resolution: 2.03 a.
32% identity, 91% coverage of query (127 bits)
3cmfA Crystal structure of human liver 5beta-reductase (akr1d1) in complex with NADP and cortisone. Resolution 1.90 a.
32% identity, 91% coverage of query (127 bits)
3cavA Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 5beta-pregnan-3,20-dione
32% identity, 91% coverage of query (127 bits)
3casA Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 4-androstenedione
32% identity, 91% coverage of query (127 bits)
3caqA Crystal structure of 5beta-reductase (akr1d1) in complex with NADPH
32% identity, 91% coverage of query (127 bits)
3buvA Crystal structure of human delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and hepes. Resolution: 1.35 a.
32% identity, 91% coverage of query (127 bits)
AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
29% identity, 94% coverage of query (126 bits)
4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
30% identity, 94% coverage of query (126 bits)
Redox2 / A0A2P1GIY9 Redox 2 from Catharanthus roseus (see paper)
REDX2_CATRO / A0A2P1GIY9 Protein REDOX 2; EC 1.7.1.- from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
34% identity, 86% coverage of query (126 bits)
AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
30% identity, 94% coverage of query (126 bits)
xyrB / A2QQ97 D-xylose reductase XyrB (EC 1.1.1.21; EC 1.1.1.431) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 4 papers)
29% identity, 92% coverage of query (126 bits)
4jtrB Akr1c2 complex with ibuprofen
30% identity, 94% coverage of query (126 bits)
1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
30% identity, 94% coverage of query (126 bits)
4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
30% identity, 94% coverage of query (126 bits)
4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
30% identity, 94% coverage of query (126 bits)
1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
30% identity, 94% coverage of query (126 bits)
4jtrA Akr1c2 complex with ibuprofen
30% identity, 94% coverage of query (126 bits)
4jtqA Akr1c2 complex with flurbiprofen
30% identity, 94% coverage of query (126 bits)
4jqaA Akr1c2 complex with mefenamic acid
30% identity, 94% coverage of query (126 bits)
4jq4A Akr1c2 complex with indomethacin
30% identity, 94% coverage of query (126 bits)
4jq3A Akr1c2 complex with zomepirac
30% identity, 94% coverage of query (126 bits)
4jq2A Akr1c2 complex with sulindac
30% identity, 94% coverage of query (126 bits)
4jq1A Akr1c2 complex with naproxen
30% identity, 94% coverage of query (126 bits)
4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
30% identity, 94% coverage of query (126 bits)
2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
30% identity, 94% coverage of query (126 bits)
1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
30% identity, 94% coverage of query (126 bits)
3h7uA / Q0PGJ6 Crystal structure of the plant stress-response enzyme akr4c9 (see paper)
29% identity, 83% coverage of query (125 bits)
AK1CL_MOUSE / Q91WR5 Aldo-keto reductase family 1 member C21; 17-alpha-hydroxysteroid dehydrogenase; 17-alpha-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase type 1; DD1; Dihydrodiol dehydrogenase type 3; DD3; EC 1.1.1.-; EC 1.1.1.209 from Mus musculus (Mouse) (see 7 papers)
Q91WR5 estradiol 17alpha-dehydrogenase (EC 1.1.1.148); 3(or 17)alpha-hydroxysteroid dehydrogenase (EC 1.1.1.209); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Mus musculus (see 5 papers)
30% identity, 94% coverage of query (125 bits)
3cv6A / Q91WR5 The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase gg225.226pp mutant in complex with inhibitor and cofactor NADP+. (see paper)
30% identity, 94% coverage of query (125 bits)
AKR4C9 / Q0PGJ6 aldo-keto reductase family 4 member C9 (EC 1.1.1.21; EC 1.1.1.210; EC 1.1.1.2; EC 1.1.1.54) from Arabidopsis thaliana (see 2 papers)
AKRC9_ARATH / Q0PGJ6 NADPH-dependent aldo-keto reductase, chloroplastic; AtChlAKR; Aldo-keto reductase family 4 member C9; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
29% identity, 83% coverage of query (125 bits)
T2HVB4 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Oryctolagus cuniculus (see paper)
30% identity, 87% coverage of query (125 bits)
ALRA_DICDI / Q6IMN8 Aldose reductase A; ARA; Aldehyde reductase A; AlrA; EC 1.1.1.21 from Dictyostelium discoideum (Social amoeba) (see paper)
Q6IMN8 methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Dictyostelium discoideum (see paper)
28% identity, 87% coverage of query (125 bits)
ALR / D2DII9 erythrose reductase monomer (EC 1.1.1.2) from Starmerella magnoliae (see 2 papers)
36% identity, 87% coverage of query (125 bits)
Q95JH5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see paper)
28% identity, 94% coverage of query (125 bits)
2ipfA Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP+ and epi-testosterone
30% identity, 94% coverage of query (125 bits)
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