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Searching for up to 100 curated homologs for SMc00672 FitnessBrowser__Smeli:SMc00672 (344 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.12.6 / Q9KKE3 HutX aka HISX, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    100% identity, 100% coverage of query (699 bits)

AO356_09620 ABC transporter for L-Histidine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    49% identity, 99% coverage of query (329 bits)

7yleA / A3SME7 Rndmpx in complex with dmsp (see paper)
    30% identity, 91% coverage of query (136 bits)

Build an alignment

Build an alignment for SMc00672 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

1r9qA / P0AFM2 Structure analysis of prox in complex with proline betaine (see paper)
    26% identity, 74% coverage of query (74.7 bits)

OsrA / b2679 glycine betaine ABC transporter periplasmic binding protein ProX (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
proX / P0AFM2 glycine betaine ABC transporter periplasmic binding protein ProX (EC 7.6.2.9) from Escherichia coli (strain K12) (see 2 papers)
PROX_ECOLI / P0AFM2 Glycine betaine/proline betaine-binding periplasmic protein; GBBP from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.12.1 / P0AFM2 ProX aka ProU aka B2679, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 6 papers)
proX / RF|NP_417165 glycine betaine-binding periplasmic protein from Escherichia coli K12 (see 7 papers)
    26% identity, 74% coverage of query (74.7 bits)

A0A077T7U5 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    26% identity, 82% coverage of query (70.9 bits)

TMOX_PELUB / Q4FL33 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Pelagibacter ubique (strain HTCC1062) (see paper)
    22% identity, 86% coverage of query (61.2 bits)

TMOX_RUEPO / Q5LT66 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see 2 papers)
    22% identity, 85% coverage of query (53.9 bits)

4xz6A / Q5LT66 Tmox in complex with tmao (see paper)
    22% identity, 85% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory