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Searching for up to 100 curated homologs for SMc00926 FitnessBrowser__Smeli:SMc00926 (443 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

Removed hits that are identical to the query, leaving 14

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PGA1_c29700 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) from Phaeobacter inhibens BS107
    65% identity, 97% coverage of query (563 bits)

Psest_3839 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) from Pseudomonas stutzeri RCH2
    44% identity, 95% coverage of query (350 bits)

RR42_RS17315 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) from Cupriavidus basilensis FW507-4G11
    42% identity, 95% coverage of query (334 bits)

YghL / b4467 glycolate dehydrogenase, putative iron-sulfur subunit (EC 1.1.99.14) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
glcF / P52074 glycolate dehydrogenase, putative iron-sulfur subunit (EC 1.1.99.14) from Escherichia coli (strain K12) (see 4 papers)
GLCF_ECOLI / P52074 Glycolate oxidase iron-sulfur subunit; Glycolate dehydrogenase subunit GlcF; Glycolate oxidase subunit GlcF; EC 1.1.99.14 from Escherichia coli (strain K12) (see 4 papers)
glcF / RF|YP_026190.1 glycolate oxidase, iron-sulfur subunit from Escherichia coli K12 (see paper)
glcF / AAB02532.1 glycolate oxidase subunit, (Fe-S)protein from Escherichia coli (see paper)
    42% identity, 95% coverage of query (330 bits)

Build an alignment

Build an alignment for SMc00926 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

DVU_3033 / Q726S3 quinone-dependent L-lactate dehydrogenase large subunit (EC 1.1.2.3) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 4 papers)
    27% identity, 89% coverage of query (150 bits)

DVU_3028 / Q726S8 quinone-dependent D-lactate dehydrogenase iron-sulfur subunit (EC 1.1.2.5) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 3 papers)
    26% identity, 89% coverage of query (125 bits)

Q88DT2 D-2-hydroxyacid dehydrogenase (quinone) (EC 1.1.5.10); D-lactate dehydrogenase (quinone) (EC 1.1.5.12) from Pseudomonas putida (see paper)
    31% identity, 81% coverage of query (87.4 bits)

GlpC / b2243 anaerobic glycerol-3-phosphate dehydrogenase subunit C (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
glpC / P0A996 anaerobic glycerol-3-phosphate dehydrogenase subunit C (EC 1.1.5.3) from Escherichia coli (strain K12) (see 4 papers)
    24% identity, 91% coverage of query (83.2 bits)

BPHYT_RS03150 Phosphoglycerate dehydrogenase (EC:1.1.1.95) from Burkholderia phytofirmans PsJN
    23% identity, 83% coverage of query (72.8 bits)

HDRD_METMA / Q8PVW3 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
    22% identity, 87% coverage of query (71.2 bits)

hdrD / P96797 CoB-CoM heterodisulfide reductase catalytic subunit D (EC 1.8.98.1) from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
HDRD_METBF / P96797 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
TC 3.D.7.1.1 / P96797 HDRD, component of H2:heterodisulfide oxidoreductase, HHO. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf from Methanosarcina barkeri (see 3 papers)
hdrD / GB|AAZ70545.1 CoB--CoM heterodisulfide reductase iron-sulfur subunit D; EC 1.8.98.1 from Methanosarcina barkeri str. Fusaro (see 3 papers)
    20% identity, 91% coverage of query (70.9 bits)

HSERO_RS19500 Putative phosphoglycerate dehydrogenase (EC:1.1.1.95) from Herbaspirillum seropedicae SmR1
    21% identity, 87% coverage of query (66.2 bits)

GYD1 / A8J2E9 glycolate dehydrogenase (EC 1.1.99.14) from Chlamydomonas reinhardtii (see 4 papers)
    23% identity, 80% coverage of query (57.4 bits)

dld-II / Q8EGS3 D-lactate dehydrogenase Dld-II (EC 1.1.2.5) from Shewanella oneidensis (strain MR-1) (see paper)
    23% identity, 91% coverage of query (55.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory