Searching for up to 100 curated homologs for SMc01166 FitnessBrowser__Smeli:SMc01166 (617 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 99
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q9L3I0 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Rhizobium leguminosarum (see paper)
72% identity, 100% coverage of query (907 bits)
HSERO_RS12130 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Herbaspirillum seropedicae SmR1
59% identity, 99% coverage of query (717 bits)
PGA1_c07250 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Phaeobacter inhibens BS107
50% identity, 100% coverage of query (570 bits)
iolD / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase (EC 3.7.1.22) from Bacillus subtilis (strain 168) (see 2 papers)
IOLD_BACSU / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; THcHDO hydrolase; EC 3.7.1.22 from Bacillus subtilis (strain 168) (see paper)
P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Bacillus subtilis (see paper)
42% identity, 99% coverage of query (520 bits)
Pf6N2E2_517 Epi-inositol hydrolase (EC 3.7.1.-) from Pseudomonas fluorescens FW300-N2E2
48% identity, 96% coverage of query (513 bits)
AO356_23185 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2C3
48% identity, 96% coverage of query (510 bits)
PS417_11870 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas simiae WCS417
45% identity, 99% coverage of query (504 bits)
AO353_21360 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2E3
45% identity, 99% coverage of query (499 bits)
BWI76_RS03090 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Klebsiella michiganensis M5al
44% identity, 99% coverage of query (499 bits)
Pf1N1B4_4279 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N1B4
46% identity, 96% coverage of query (495 bits)
Build an alignment for SMc01166 and 10 homologs with ≥ 30% identity
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P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
29% identity, 92% coverage of query (184 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
29% identity, 83% coverage of query (178 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
30% identity, 77% coverage of query (166 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
26% identity, 83% coverage of query (164 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
28% identity, 76% coverage of query (164 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
26% identity, 77% coverage of query (159 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
26% identity, 88% coverage of query (158 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
27% identity, 80% coverage of query (158 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
26% identity, 88% coverage of query (154 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
27% identity, 82% coverage of query (152 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
26% identity, 97% coverage of query (150 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
27% identity, 74% coverage of query (142 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
27% identity, 83% coverage of query (140 bits)
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
25% identity, 83% coverage of query (138 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
27% identity, 88% coverage of query (137 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
26% identity, 85% coverage of query (136 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
24% identity, 97% coverage of query (131 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
24% identity, 97% coverage of query (128 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
24% identity, 97% coverage of query (128 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
24% identity, 97% coverage of query (128 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
24% identity, 97% coverage of query (128 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
24% identity, 87% coverage of query (127 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
24% identity, 97% coverage of query (127 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
24% identity, 97% coverage of query (126 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
27% identity, 73% coverage of query (125 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
24% identity, 97% coverage of query (124 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
26% identity, 84% coverage of query (124 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
24% identity, 97% coverage of query (124 bits)
Q5VB44 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
27% identity, 77% coverage of query (124 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
25% identity, 93% coverage of query (124 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
25% identity, 93% coverage of query (124 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
25% identity, 86% coverage of query (124 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
25% identity, 86% coverage of query (124 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
25% identity, 86% coverage of query (124 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
25% identity, 86% coverage of query (123 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
25% identity, 86% coverage of query (123 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
25% identity, 93% coverage of query (123 bits)
Q5VB49 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
27% identity, 73% coverage of query (122 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
25% identity, 86% coverage of query (120 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
26% identity, 73% coverage of query (120 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
25% identity, 82% coverage of query (119 bits)
als / CAA66718.1 acetolactate synthase from Synechocystis sp (see paper)
25% identity, 85% coverage of query (117 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
25% identity, 82% coverage of query (117 bits)
ILV2 acetolactate synthase; EC 2.2.1.6 from Candida albicans (see paper)
24% identity, 93% coverage of query (117 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
23% identity, 91% coverage of query (117 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
24% identity, 91% coverage of query (117 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
23% identity, 91% coverage of query (117 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
25% identity, 96% coverage of query (116 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
26% identity, 73% coverage of query (116 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
23% identity, 91% coverage of query (116 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
27% identity, 75% coverage of query (115 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
25% identity, 73% coverage of query (112 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
25% identity, 73% coverage of query (112 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
25% identity, 73% coverage of query (112 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
25% identity, 73% coverage of query (112 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
25% identity, 73% coverage of query (112 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
25% identity, 73% coverage of query (112 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
25% identity, 73% coverage of query (112 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
25% identity, 73% coverage of query (112 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
25% identity, 73% coverage of query (112 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
25% identity, 73% coverage of query (112 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
25% identity, 73% coverage of query (112 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
25% identity, 73% coverage of query (112 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
25% identity, 73% coverage of query (112 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
26% identity, 74% coverage of query (111 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
26% identity, 74% coverage of query (111 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
25% identity, 73% coverage of query (111 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
25% identity, 73% coverage of query (111 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
25% identity, 73% coverage of query (111 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 74% coverage of query (111 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 74% coverage of query (111 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase
26% identity, 74% coverage of query (110 bits)
7egvA / A0A2N1LPC4 Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
25% identity, 85% coverage of query (104 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
24% identity, 73% coverage of query (97.4 bits)
7pt4A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone
24% identity, 82% coverage of query (95.5 bits)
7pt4B / P0DUV9 Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone (see paper)
24% identity, 82% coverage of query (95.1 bits)
7pt1A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with substrate 2-hib-coa and inactive cofactor 3-deaza-thdp
24% identity, 82% coverage of query (95.1 bits)
HACL_ACTC0 / P0DUV9 2-hydroxyacyl-CoA lyase; AcHACL; HACL; 2-hydroxyisobutyryl-CoA lyase; EC 4.1.-.- from Actinomycetospora chiangmaiensis (strain DSM 45062 / JCM 15998 / CCTCC AA 205017 / NBRC 104400 / YIM 0006) (see 2 papers)
24% identity, 82% coverage of query (95.1 bits)
1upaA Carboxyethylarginine synthase from streptomyces clavuligerus (semet structure)
25% identity, 79% coverage of query (92.8 bits)
2ihuA Carboxyethylarginine synthase from streptomyces clavuligerus: putative reaction intermediate complex
24% identity, 79% coverage of query (92.4 bits)
2ihvA / Q9LCV9 Carboxyethylarginine synthase from streptomyces clavuligerus: 5- guanidinovaleric acid complex (see paper)
24% identity, 79% coverage of query (92.4 bits)
ceaS / Q9LCV9 N2-(carboxyethyl)arginine synthase subunit (EC 2.5.1.66) from Streptomyces clavuligerus (see paper)
CEAS_STRCL / Q9LCV9 N(2)-(2-carboxyethyl)arginine synthase; CEA synthetase; CEAS; EC 2.5.1.66 from Streptomyces clavuligerus (see 3 papers)
24% identity, 79% coverage of query (92.0 bits)
2ihuC Carboxyethylarginine synthase from streptomyces clavuligerus: putative reaction intermediate complex
24% identity, 79% coverage of query (92.0 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
23% identity, 81% coverage of query (85.5 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
23% identity, 81% coverage of query (85.5 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
23% identity, 81% coverage of query (85.5 bits)
2djiA / A9X9K8 Crystal structure of pyruvate oxidase from aerococcus viridans containing fad (see paper)
23% identity, 93% coverage of query (84.7 bits)
1v5gA Crystal structure of the reaction intermediate between pyruvate oxidase containing fad and tpp, and substrate pyruvate
23% identity, 93% coverage of query (84.7 bits)
1v5fA Crystal structure of pyruvate oxidase complexed with fad and tpp, from aerococcus viridans
23% identity, 93% coverage of query (84.7 bits)
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Lawrence Berkeley National Laboratory