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Searching for up to 100 curated homologs for SMc02118 SMc02118 general L-amino acid-binding periplasmic ABC transporter protein (341 a.a.)

Found high-coverage hits (≥70%) to 13 curated proteins.

Removed hits that are identical to the query, leaving 12

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AAPJ_RHIJ3 / Q52812 General L-amino acid-binding periplasmic protein AapJ from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see 2 papers)
TC 3.A.1.3.8 / Q52812 AapJ, component of General L-amino acid porter; transports basic and acidic amino acids preferentially, but also transports aliphatic amino acids (catalyzes both uptake and efflux) from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
aapJ / CAA57933.1 general amino acid ABC type transporter from Rhizobium leguminosarum (see paper)
    81% identity, 100% coverage of query (599 bits)

4z9nB / A0A0M3KL33 Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
    71% identity, 94% coverage of query (503 bits)

Pf6N2E2_5402 ABC transporter for D-Alanine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
    55% identity, 100% coverage of query (406 bits)

TC 3.A.1.3.7 / Q52663 BztA, component of Glutamate/glutamine/aspartate/asparagine porter from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
    60% identity, 93% coverage of query (369 bits)

TC 3.A.1.3.18 / Q8YPM9 NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
    50% identity, 98% coverage of query (343 bits)

Build an alignment

Build an alignment for SMc02118 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
    29% identity, 70% coverage of query (83.2 bits)

cjaA / CAJ20048.1 glutamine-binding protein from Campylobacter jejuni (see paper)
    26% identity, 79% coverage of query (83.2 bits)

4zv2A An ancestral arginine-binding protein bound to glutamine
    29% identity, 70% coverage of query (80.9 bits)

AO353_21710 ABC transporter for D-glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
    28% identity, 77% coverage of query (74.7 bits)

AO356_00480 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    25% identity, 75% coverage of query (70.1 bits)

2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
    25% identity, 70% coverage of query (65.5 bits)

Pf6N2E2_2053 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
    25% identity, 70% coverage of query (64.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory