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Searching for up to 100 curated homologs for SMc02378 FitnessBrowser__Smeli:SMc02378 (332 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7yleA / A3SME7 Rndmpx in complex with dmsp (see paper)
    39% identity, 93% coverage of query (225 bits)

TC 3.A.1.12.6 / Q9KKE3 HutX aka HISX, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    34% identity, 92% coverage of query (160 bits)

AO356_09620 ABC transporter for L-Histidine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    30% identity, 99% coverage of query (147 bits)

Build an alignment

Build an alignment for SMc02378 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.12.12 / Q9HTI6 Putative uncharacterized protein, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa (see paper)
    23% identity, 91% coverage of query (59.3 bits)

TMOX_RUEPO / Q5LT66 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see 2 papers)
    25% identity, 95% coverage of query (53.5 bits)

TC 3.A.1.12.9 / Q8U4S3 OtaC, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
    23% identity, 94% coverage of query (50.1 bits)

4xz6A / Q5LT66 Tmox in complex with tmao (see paper)
    24% identity, 88% coverage of query (49.3 bits)

A0A077T7R8 ABC-type quaternary amine transporter (subunit 1/2) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    25% identity, 72% coverage of query (48.5 bits)

TMOX_PELUB / Q4FL33 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Pelagibacter ubique (strain HTCC1062) (see paper)
    22% identity, 95% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory