Searching for up to 100 curated homologs for SMc02519 FitnessBrowser__Smeli:SMc02519 (356 a.a.)
Found high-coverage hits (≥70%) to 66 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.1.35 / G3LHY8 GlpS, component of Glycerol uptake porter, GlpSTPQV from Rhizobium leguminosarum bv. viciae
73% identity, 99% coverage of query (536 bits)
Ac3H11_791 ABC transporter for Glycerol, ATPase component 1 from Acidovorax sp. GW101-3H11
46% identity, 98% coverage of query (297 bits)
SMc03065 ABC transporter for D-maltose/D-trehalose/sucrose, ATPase component (AglK) from Sinorhizobium meliloti 1021
TC 3.A.1.1.8 / Q9Z3R9 AglK aka R00699 aka SMC03065, component of Sucrose/maltose/trehalose porter (sucrose-inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
36% identity, 98% coverage of query (202 bits)
TC 3.A.1.1.5 / P54933 SmoK aka POLK, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
35% identity, 88% coverage of query (195 bits)
TC 3.A.1.1.49 / O30494 MtlK, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
34% identity, 99% coverage of query (194 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
34% identity, 97% coverage of query (191 bits)
PS417_12700 ABC transporter for D-Mannitol and D-Sorbitol, ATPase component from Pseudomonas simiae WCS417
34% identity, 99% coverage of query (191 bits)
PGA1_c13180 ABC transporter for D-Sorbitol, ATPase component from Phaeobacter inhibens BS107
34% identity, 98% coverage of query (189 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
33% identity, 98% coverage of query (187 bits)
TC 3.A.1.1.10 / Q9KWT9 AlgS, component of Alginate (MW 27,000 Da) (and Alginate oligosaccharides) uptake porter. Sphingomonas species A1 is a 'pit-forming' bacterium that directly incorporates alginate into its cytoplasm through a pit-dependent transport system, termed a 'superchannel' (Murata et al., 2008). The pit is a novel organ acquired through the fluidity and reconstitution of cell surface molecules, and through cooperation with the transport machinery in the cells. It confers upon bacterial cells a more efficient way to secure and assimilate macromolecules from Sphingomonas sp (see paper)
algS / BAB03314.1 AlgS from Sphingomonas sp (see paper)
31% identity, 98% coverage of query (186 bits)
mtlK / Q4KC54 polyol ABC-type transporterATP-binding component MtlK from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
36% identity, 87% coverage of query (186 bits)
MALK_THELN / Q9YGA6 Trehalose/maltose import ATP-binding protein MalK; EC 7.5.2.1 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 5 papers)
35% identity, 88% coverage of query (186 bits)
TC 3.A.1.1.16 / Q8TZQ3 MalK aka PF1933, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
33% identity, 97% coverage of query (186 bits)
AO356_00010 ABC transporter for D-Sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2C3
33% identity, 99% coverage of query (186 bits)
TC 3.A.1.1.46 / P77481 Putative uncharacterized ABC transporter ATP-binding protein YcjV, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
31% identity, 95% coverage of query (186 bits)
TC 3.A.1.1.24 / TC 3.A.1.1.25 / Q72L52 Sugar-binding transport ATP-binding protein aka MalK1 aka TT_C0211, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
32% identity, 97% coverage of query (185 bits)
SM_b21106 ABC transporter for L-Fucose, ATPase component from Sinorhizobium meliloti 1021
34% identity, 90% coverage of query (184 bits)
1g291 / Q9YGA6 Malk (see paper)
35% identity, 88% coverage of query (183 bits)
Pf6N2E2_1960 ABC transporter for D-sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2E2
32% identity, 99% coverage of query (183 bits)
TC 3.A.1.1.22 / Q9X103 MalK; aka Sugar ABC transporter, ATP-binding protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
34% identity, 83% coverage of query (182 bits)
TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
33% identity, 95% coverage of query (182 bits)
Pf1N1B4_5115 sucrose ABC transporter, ATPase component from Pseudomonas fluorescens FW300-N1B4
33% identity, 87% coverage of query (182 bits)
SM_b21216 ABC transporter for D-Glucosamine, ATPase component from Sinorhizobium meliloti 1021
35% identity, 89% coverage of query (180 bits)
PfGW456L13_1897 ABC transporter for D-Galactose and D-Glucose, ATPase component from Pseudomonas fluorescens GW456-L13
32% identity, 91% coverage of query (179 bits)
SM_b20328 ABC transporter for D-trehalose/D-maltose/sucrose, ATPase component (ThuK) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q4 ThuK aka RB0314 aka SMB20328, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
33% identity, 99% coverage of query (179 bits)
A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
35% identity, 84% coverage of query (177 bits)
TC 3.A.1.1.30 / Q88P35 GtsD (GLcK), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
32% identity, 91% coverage of query (176 bits)
PS417_22130 glucose/xylose ABC transporter, ATPase component from Pseudomonas simiae WCS417
32% identity, 91% coverage of query (175 bits)
Ac3H11_2066 glucose ABC transporter, ATPase component from Acidovorax sp. GW101-3H11
30% identity, 92% coverage of query (175 bits)
SMc02869 N-Acetyl-D-glucosamine ABC transport system, ATPase component from Sinorhizobium meliloti 1021
37% identity, 74% coverage of query (175 bits)
Dshi_1648 glucose/maltose/trehalose/sucrose ABC transporter, ATPase component from Dinoroseobacter shibae DFL-12
35% identity, 87% coverage of query (174 bits)
Dshi_0546 ABC transporter for Xylitol, ATPase component from Dinoroseobacter shibae DFL-12
36% identity, 78% coverage of query (174 bits)
TC 3.A.1.1.12 / Q9AI63 PalK, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
31% identity, 89% coverage of query (173 bits)
TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
32% identity, 90% coverage of query (172 bits)
UgpC / b3450 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
UgpC / P10907 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli (strain K12) (see 2 papers)
UGPC_ECOLI / P10907 sn-glycerol-3-phosphate import ATP-binding protein UgpC; EC 7.6.2.10 from Escherichia coli (strain K12) (see 9 papers)
TC 3.A.1.1.3 / P10907 UgpC aka B3450, component of Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P from Escherichia coli (see 12 papers)
32% identity, 89% coverage of query (171 bits)
Q8NMV1 ABC-type maltose transporter (EC 7.5.2.1) from Corynebacterium glutamicum (see paper)
TC 3.A.1.1.45 / Q8NMV1 ABC-type sugar transport system, ATPase component, component of Maltose transporter, MusEFGKI from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
34% identity, 85% coverage of query (171 bits)
TC 3.A.1.1.27 / Q8DT25 MalK, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
32% identity, 81% coverage of query (171 bits)
Build an alignment for SMc02519 and 37 homologs with ≥ 30% identity
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TC 3.A.1.1.34 / O32151 Uncharacterized ABC transporter ATP-binding protein YurJ, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (strain 168)
29% identity, 97% coverage of query (171 bits)
TC 3.A.1.1.28 / Q00752 MsmK aka SMU.882, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
30% identity, 89% coverage of query (171 bits)
SMc04256 ABC transporter for D-Cellobiose and D-Salicin, ATPase component from Sinorhizobium meliloti 1021
30% identity, 95% coverage of query (170 bits)
B9J850 pterin deaminase (EC 3.5.4.11) from Agrobacterium tumefaciens (see paper)
31% identity, 97% coverage of query (170 bits)
HSERO_RS17020 ABC transporter for D-sorbitol/xylitol, ATPase component from Herbaspirillum seropedicae SmR1
34% identity, 94% coverage of query (169 bits)
smoE / Q7CS28 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter ATP-binding subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
30% identity, 97% coverage of query (169 bits)
TC 3.A.1.1.15 / Q97ZC0 TreV, component of Trehalose porter from Sulfolobus solfataricus (see paper)
30% identity, 99% coverage of query (169 bits)
TC 3.A.1.1.6 / Q48394 CymD, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
31% identity, 89% coverage of query (169 bits)
SM_b20002 ABC transporter for Lactose, ATPase component from Sinorhizobium meliloti 1021
32% identity, 88% coverage of query (168 bits)
TC 3.A.1.1.19 / Q8L122 PalK, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter (see 3 papers)
palK / BAB96542.1 PalK from Agrobacterium tumefaciens (see 3 papers)
35% identity, 86% coverage of query (167 bits)
MSIK_STRCO / Q9L0Q1 Diacetylchitobiose uptake system ATP-binding protein MsiK; EC 7.5.2.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
TC 3.A.1.1.33 / TC 3.A.1.1.36 / Q9L0Q1 ABC transporter ATP-binding protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces coelicolor (see paper)
33% identity, 85% coverage of query (166 bits)
Q70HW1 ABC-type maltose transporter (EC 7.5.2.1) from Alicyclobacillus acidocaldarius (see paper)
malK / CAE45698.1 ATP-binding MalK protein from Alicyclobacillus acidocaldarius subsp. acidocaldarius (see paper)
29% identity, 99% coverage of query (166 bits)
TC 3.A.1.1.23 / P96483 MsiK protein, component of The cellobiose/cellotriose (and possibly higher cellooligosaccharides), CebEFGMsiK [MsiK functions to energize several ABC transporters including those for maltose/maltotriose and trehalose] from Streptomyces reticuli (see paper)
33% identity, 81% coverage of query (165 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
30% identity, 88% coverage of query (160 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
29% identity, 88% coverage of query (159 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
29% identity, 88% coverage of query (159 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
29% identity, 88% coverage of query (159 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
29% identity, 88% coverage of query (159 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
29% identity, 88% coverage of query (159 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
29% identity, 88% coverage of query (159 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
29% identity, 88% coverage of query (158 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
30% identity, 91% coverage of query (157 bits)
8hprD Lpqy-sugabc in state 4
31% identity, 82% coverage of query (152 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
31% identity, 83% coverage of query (152 bits)
8hprC Lpqy-sugabc in state 4
31% identity, 81% coverage of query (149 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
29% identity, 83% coverage of query (136 bits)
2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
24% identity, 88% coverage of query (100 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
26% identity, 73% coverage of query (75.9 bits)
3gd7A / P13569,P68187 Crystal structure of human nbd2 complexed with n6-phenylethyl-atp (p- atp)
25% identity, 80% coverage of query (69.7 bits)
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