Searching for up to 100 curated homologs for SMc02775 FitnessBrowser__Smeli:SMc02775 (339 a.a.)
Found high-coverage hits (≥70%) to 53 curated proteins.
Removed hits that are identical to the query, leaving 52
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BPHYT_RS34225 L-fucose dehydrogenase (EC 1.1.1.122) from Burkholderia phytofirmans PsJN
52% identity, 90% coverage of query (283 bits)
PLD_MICLT / Q76KC2 Pyridoxal 4-dehydrogenase; EC 1.1.1.107 from Microbacterium luteolum (Aureobacterium luteolum) (see paper)
43% identity, 97% coverage of query (262 bits)
FCDH_PSESP / Q52472 D-threo-aldose 1-dehydrogenase; L-fucose dehydrogenase; EC 1.1.1.122 from Pseudomonas sp.
Q52472 D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) from Pseudomonas sp. (see paper)
41% identity, 86% coverage of query (220 bits)
7eziA / Q2QQV2 Rice l-galactose dehydrogenase (apo form)
30% identity, 94% coverage of query (127 bits)
7ezlA Rice l-galactose dehydrogenase (holo form)
30% identity, 94% coverage of query (127 bits)
Build an alignment for SMc02775 and 5 homologs with ≥ 30% identity
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LGALDH / O81884 L-galactose dehydrogenase (EC 1.1.1.316) from Arabidopsis thaliana (see paper)
GALDH_ARATH / O81884 L-galactose dehydrogenase; At-GalDH; L-GalDH; EC 1.1.1.316 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O81884 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Arabidopsis thaliana (see paper)
L-GalDH / CAD10386.1 L-galactose dehydrogenase from Arabidopsis thaliana (see paper)
28% identity, 95% coverage of query (118 bits)
7svqA / Q6BDJ2 Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
27% identity, 95% coverage of query (117 bits)
Q6BDJ2 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Spinacia oleracea (see paper)
GDH / BAD32687.1 L-galactose dehydrogenase from Spinacia oleracea (see paper)
27% identity, 95% coverage of query (117 bits)
E9M5S4 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Citrus unshiu (see paper)
28% identity, 92% coverage of query (115 bits)
Q84L20 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Malus domestica (see paper)
27% identity, 91% coverage of query (114 bits)
C0LVA5 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Actinidia eriantha (see paper)
27% identity, 92% coverage of query (112 bits)
lgaA / A6KWY2 L-galactose dehydrogenase from Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) (see paper)
26% identity, 94% coverage of query (108 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
25% identity, 94% coverage of query (93.6 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
25% identity, 96% coverage of query (92.0 bits)
1ynpB / Q9KE47 Aldo-keto reductase akr11c1 from bacillus halodurans (apo form) (see paper)
29% identity, 91% coverage of query (92.0 bits)
1ynqB Aldo-keto reductase akr11c1 from bacillus halodurans (holo form)
29% identity, 91% coverage of query (92.0 bits)
3erpA Structure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimurium
28% identity, 89% coverage of query (86.7 bits)
1ynpA Aldo-keto reductase akr11c1 from bacillus halodurans (apo form)
28% identity, 91% coverage of query (86.7 bits)
5t79A / Q8ZNA1 X-ray crystal structure of a novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol (see paper)
28% identity, 89% coverage of query (81.6 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
27% identity, 91% coverage of query (81.3 bits)
GME68_PESMI / A0A5B8YXI2 Aryl-alcohol dehydrogenase GME11368; Dibenzodioxocinones biosynthesis cluster protein GME11368; EC 1.1.1.- from Pestalotiopsis microspora (see 2 papers)
27% identity, 93% coverage of query (79.0 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
25% identity, 97% coverage of query (77.8 bits)
8hw0A / A0A6B8QIS5 The structure of akr6d1
25% identity, 91% coverage of query (77.8 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
26% identity, 91% coverage of query (72.4 bits)
6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
26% identity, 91% coverage of query (71.2 bits)
KCAB_ORYSJ / Q40648 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
24% identity, 91% coverage of query (68.9 bits)
Q5FQJ0 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
25% identity, 95% coverage of query (68.6 bits)
4aubB / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
25% identity, 96% coverage of query (68.2 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
25% identity, 91% coverage of query (67.8 bits)
3n6qD Crystal structure of yghz from e. Coli
25% identity, 96% coverage of query (66.2 bits)
Gpr / b3001 L-glyceraldehyde 3-phosphate reductase from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gpr / Q46851 L-glyceraldehyde 3-phosphate reductase (EC 1.1.1.21) from Escherichia coli (strain K12) (see 7 papers)
GPR_ECOLI / Q46851 L-glyceraldehyde 3-phosphate reductase; GAP reductase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
25% identity, 96% coverage of query (65.1 bits)
AMT2_ALTAL / Q75ZG2 Aldo-keto reductase AMT2; AM-toxin biosynthesis protein 2; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
24% identity, 97% coverage of query (64.7 bits)
4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate
26% identity, 91% coverage of query (63.9 bits)
4aubF / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
25% identity, 96% coverage of query (62.4 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
24% identity, 94% coverage of query (62.4 bits)
mtmW / Q194Q1 mithramycin dehydrogenase from Streptomyces argillaceus (see 2 papers)
24% identity, 91% coverage of query (60.5 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
23% identity, 99% coverage of query (60.1 bits)
AFTS1_ALTAL / Q75ZG3 Aldo-keto reductase AFTS1; AF-toxin biosynthesis protein S1; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
24% identity, 83% coverage of query (60.1 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
23% identity, 99% coverage of query (60.1 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
24% identity, 94% coverage of query (57.8 bits)
VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus (see paper)
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus (see paper)
23% identity, 85% coverage of query (56.6 bits)
YgdS / b2834 putative NADP(H)-dependent aldo-keto reductase Tas from Escherichia coli K-12 substr. MG1655 (see 6 papers)
1lqaA / P0A9T4 Tas protein from escherichia coli in complex with NADPH (see paper)
tas protein Tas from Escherichia coli str. K12 substr. MG1655 (see paper)
28% identity, 91% coverage of query (56.2 bits)
P0A9T4 Protein tas from Escherichia coli (strain K12)
28% identity, 91% coverage of query (56.2 bits)
eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
25% identity, 88% coverage of query (55.1 bits)
KCAB1_RAT / P63144 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Rattus norvegicus (Rat) (see 9 papers)
24% identity, 91% coverage of query (54.7 bits)
SAN2_FUSV7 / C7ZBE5 Aldo-keto reductase NECHADRAFT_45914; Sansalvamide biosynthesis cluster protein NECHADRAFT_45914; EC 1.1.1.- from Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4) (Fusarium solani subsp. pisi) (see paper)
23% identity, 86% coverage of query (53.1 bits)
KCAB1_HUMAN / Q14722 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Homo sapiens (Human) (see 13 papers)
24% identity, 91% coverage of query (53.1 bits)
KCAB3_XENLA / Q9PTM4 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
22% identity, 91% coverage of query (52.4 bits)
DTXS3_METRA / E9FCP6 Aldo-keto reductase dtxS3; Destruxin synthesis protein 3; EC 1.1.1.- from Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23)) (see paper)
24% identity, 86% coverage of query (51.2 bits)
8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
24% identity, 82% coverage of query (50.4 bits)
ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
23% identity, 94% coverage of query (47.0 bits)
AUSK_ASPCI / A0A0U5GHU6 Aldo-keto reductase ausK; Austinoid biosynthesis cluster protein K; EC 1.1.1.- from Aspergillus calidoustus (see 2 papers)
24% identity, 82% coverage of query (45.8 bits)
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