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Searching for up to 100 curated homologs for SMc03138 FitnessBrowser__Smeli:SMc03138 (270 a.a.)

Found high-coverage hits (≥70%) to 63 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YhfQ / b3374 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
frlD / P45543 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli (strain K12) (see 3 papers)
FRLD_ECOLI / P45543 Fructoselysine 6-kinase; EC 2.7.1.218 from Escherichia coli (strain K12) (see 2 papers)
P45543 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli (see 3 papers)
    32% identity, 96% coverage of query (109 bits)

FRLD_BACSU / O32153 Fructosamine kinase FrlD; EC 2.7.1.- from Bacillus subtilis (strain 168) (see paper)
O32153 fructoselysine 6-kinase (EC 2.7.1.218) from Bacillus subtilis (see paper)
    31% identity, 96% coverage of query (97.8 bits)

1v1aA / Q53W83 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
    31% identity, 89% coverage of query (72.4 bits)

1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp
    31% identity, 89% coverage of query (72.4 bits)

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    31% identity, 89% coverage of query (72.0 bits)

Build an alignment

Build an alignment for SMc03138 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2c49A / Q57849 Crystal structure of methanocaldococcus jannaschii nucleoside kinase - an archaeal member of the ribokinase family (see paper)
    29% identity, 84% coverage of query (68.6 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    25% identity, 94% coverage of query (68.6 bits)

NK_METJA / Q57849 Nucleoside kinase; NK; ATP-dependent nucleoside monophosphokinase; Cytidine kinase; Guanosine-inosine kinase; EC 2.7.1.213; EC 2.7.1.73 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    29% identity, 84% coverage of query (68.2 bits)

scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    31% identity, 77% coverage of query (64.3 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    32% identity, 80% coverage of query (61.6 bits)

3uboA / Q92T17 The crystal structure of adenosine kinase from sinorhizobium meliloti
    29% identity, 94% coverage of query (60.5 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    26% identity, 89% coverage of query (60.1 bits)

C4M2I2 fructokinase (EC 2.7.1.4) from Entamoeba histolytica (see paper)
    22% identity, 90% coverage of query (60.1 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    25% identity, 94% coverage of query (57.0 bits)

YdjH / b1772 L-glycero-L-galacto-octuluronate kinase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ydjH / P77493 L-glycero-L-galacto-octuluronate kinase from Escherichia coli (strain K12) (see 2 papers)
    25% identity, 94% coverage of query (57.0 bits)

7fcaD / B2HEF4 Pfkb(mycobacterium marinum) (see paper)
    30% identity, 83% coverage of query (55.5 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    27% identity, 80% coverage of query (54.7 bits)

RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
    26% identity, 87% coverage of query (53.1 bits)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    26% identity, 91% coverage of query (51.2 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    26% identity, 91% coverage of query (51.2 bits)

4k8pA / Q2KDX6 Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-ethylbenzyl alcohol
    28% identity, 94% coverage of query (50.8 bits)

gacK / CAL64852.1 acarbose-7-kinase GacK from Streptomyces glaucescens (see paper)
    26% identity, 90% coverage of query (50.8 bits)

4lc4A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with guanosine
    28% identity, 94% coverage of query (50.8 bits)

4kbeA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with benzoguanamine
    28% identity, 94% coverage of query (50.8 bits)

4kanA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid
    28% identity, 94% coverage of query (50.8 bits)

4kalA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinoline-3-carboxylic acid
    28% identity, 94% coverage of query (50.8 bits)

4kahA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 4-bromo-1h-pyrazole
    28% identity, 94% coverage of query (50.8 bits)

4kadA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n1-(2.3-dihydro-1h-inden-5-yl)acetam
    28% identity, 94% coverage of query (50.8 bits)

4k9iA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with norharmane
    28% identity, 94% coverage of query (50.8 bits)

4k9cA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide and 4-methyl-3,4- dihydro-2h-1,4-benzoxazine-7-carboxylic acid
    28% identity, 94% coverage of query (50.8 bits)

4k93A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide
    28% identity, 94% coverage of query (50.8 bits)

4k8tA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with ethyl 3,4-diaminobenzoate
    28% identity, 94% coverage of query (50.8 bits)

4k8cA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with adp
    28% identity, 94% coverage of query (50.8 bits)

4jkuA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinaldic acid, nysgrc target 14306
    28% identity, 94% coverage of query (50.8 bits)

4lbxA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with cytidine
    28% identity, 94% coverage of query (50.8 bits)

4k8kA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2- aminoperimidine
    28% identity, 94% coverage of query (50.8 bits)

ADK_PHYPA / O49923 Adenosine kinase; AK; Adenosine 5'-phosphotransferase; EC 2.7.1.20 from Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens) (see paper)
    24% identity, 90% coverage of query (50.1 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    30% identity, 77% coverage of query (49.7 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    26% identity, 89% coverage of query (49.7 bits)

4wjmA / Q2YNY7 Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
    27% identity, 79% coverage of query (48.9 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    25% identity, 87% coverage of query (47.8 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    26% identity, 77% coverage of query (47.8 bits)

6a8cA Ribokinase from leishmania donovani with adp
    25% identity, 87% coverage of query (47.8 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    25% identity, 87% coverage of query (47.8 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    28% identity, 91% coverage of query (47.4 bits)

AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
    28% identity, 89% coverage of query (47.0 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 83% coverage of query (47.0 bits)

TK2029 / Q5JDG9 α-D-ribose-1-phosphate 5-kinase (ADP) (EC 2.7.1.212) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
R1PK_THEKO / Q5JDG9 ADP-dependent ribose-1-phosphate kinase; ADP-R1P kinase; ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase; Alpha-D-ribose-1-phosphate 5-kinase (ADP); EC 2.7.1.212 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    28% identity, 87% coverage of query (47.0 bits)

Pf1N1B4_6031 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N1B4
    29% identity, 89% coverage of query (47.0 bits)

1dgmA Crystal structure of adenosine kinase from toxoplasma gondii
    25% identity, 88% coverage of query (46.6 bits)

6wb7A / Q8RMD4 Acarbose kinase acbk as a complex with acarbose and amp-pnp (see paper)
    29% identity, 89% coverage of query (46.2 bits)

ACBK_ACTS5 / Q8RMD4 Acarbose 7(IV)-phosphotransferase; Acarbose 7-kinase; EC 2.7.1.187 from Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110) (see paper)
Q8RMD4 acarbose 7IV-phosphotransferase (EC 2.7.1.187) from Actinoplanes sp. (see 2 papers)
acbK / CAD29481.2 acarbose 7-kinase AcbK from Actinoplanes sp. SE50/110 (see 5 papers)
    29% identity, 89% coverage of query (46.2 bits)

6wb7C Acarbose kinase acbk as a complex with acarbose and amp-pnp
    29% identity, 89% coverage of query (46.2 bits)

1liiA Structure of t. Gondii adenosine kinase bound to adenosine 2 and amp- pcp
    24% identity, 88% coverage of query (46.2 bits)

1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
    27% identity, 91% coverage of query (45.8 bits)

RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
    27% identity, 91% coverage of query (45.8 bits)

BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
    28% identity, 91% coverage of query (45.8 bits)

1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
    27% identity, 91% coverage of query (45.8 bits)

1lijA Structure of t. Gondii adenosine kinase bound to prodrug 2 7- iodotubercidin and amp-pcp
    24% identity, 88% coverage of query (45.4 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    26% identity, 85% coverage of query (45.4 bits)

6znxC / A0A0B0SD75 Ribokinase from thermus species
    28% identity, 91% coverage of query (43.5 bits)

6wb5A Microbiome-derived acarbose kinase mak1 as a complex with acarbose and amp-pnp
    26% identity, 87% coverage of query (42.7 bits)

6wb4B / A0A1Q8WGS1 Microbiome-derived acarbose kinase mak1 labeled with selenomethionine (see paper)
    26% identity, 87% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory