Sites on a Tree

 

Searching for up to 100 curated homologs for SMc03856 FitnessBrowser__Smeli:SMc03856 (306 a.a.)

Found high-coverage hits (≥70%) to 10 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DAPF_ARATH / Q9LFG2 Diaminopimelate epimerase, chloroplastic; DAP epimerase; EC 5.1.1.7 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LFG2 diaminopimelate epimerase (EC 5.1.1.7) from Arabidopsis thaliana (see paper)
    36% identity, 92% coverage of query (181 bits)

3ejxD / Q9LFG2 Crystal structure of diaminopimelate epimerase from arabidopsis thaliana in complex with ll-azidap (see paper)
    36% identity, 92% coverage of query (181 bits)

3ekmA Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor dl-azidap
    37% identity, 90% coverage of query (179 bits)

DapF / b3809 diaminopimelate epimerase (EC 5.1.1.7) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dapF / P0A6K1 diaminopimelate epimerase (EC 5.1.1.7) from Escherichia coli (strain K12) (see 12 papers)
DAPF_ECOLI / P0A6K1 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Escherichia coli (strain K12) (see 6 papers)
    35% identity, 90% coverage of query (158 bits)

DAPF_HAEIN / P44859 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 4 papers)
2gkeA / P44859 Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor ll-azidap (see paper)
    35% identity, 90% coverage of query (158 bits)

2gkjA Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor dl-azidap
    35% identity, 90% coverage of query (158 bits)

DAPF_BACAN / Q81XR2 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Bacillus anthracis
    33% identity, 91% coverage of query (151 bits)

dcsC / D2Z026 O-ureido-serine racemase (EC 5.1.1.19) from Streptomyces lavendulae (see 2 papers)
DCSC_STRLA / D2Z026 O-ureido-serine racemase; EC 5.1.1.19 from Streptomyces lavendulae (see 3 papers)
D2Z026 O-ureido-serine racemase (EC 5.1.1.19) from Streptomyces lavendulae subsp. lavendulae (see 2 papers)
    37% identity, 90% coverage of query (129 bits)

Build an alignment

Build an alignment for SMc03856 and 8 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

DAPF_CORGL / Q8NP73 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NP73 diaminopimelate epimerase (EC 5.1.1.7) from Corynebacterium glutamicum (see paper)
    26% identity, 89% coverage of query (64.7 bits)

5m47A / Q8NP73 Crystal structure of dapf from corynebacterium glutamicum in complex with d,l-diaminopimelate (see paper)
    26% identity, 89% coverage of query (64.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory