Searching for up to 100 curated homologs for SMc04123 FitnessBrowser__Smeli:SMc04123 (265 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4uc0A / B9JYS2 Crystal structure of a purine nucleoside phosphorylase (psi-nysgrc- 029736) from agrobacterium vitis
64% identity, 99% coverage of query (312 bits)
3odgA / Q66D48 Crystal structure of xanthosine phosphorylase bound with xanthine from yersinia pseudotuberculosis
46% identity, 94% coverage of query (228 bits)
8swuA / A0A0H2YR30 Structure of clostridium perfringens pnp bound to transition state analog immucillin h and sulfate (see paper)
46% identity, 93% coverage of query (228 bits)
PUNA_GEOSE / P77834 Purine nucleoside phosphorylase 1; PNP 1; Inosine phosphorylase; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; Pu-NPase I; EC 2.4.2.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P77834 purine-nucleoside phosphorylase (EC 2.4.2.1) from Geobacillus stearothermophilus (see paper)
46% identity, 90% coverage of query (218 bits)
P46354 Purine nucleoside phosphorylase 1; PNP 1; Inosine phosphorylase; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; Pu-NPase I; EC 2.4.2.1 from Bacillus subtilis (strain 168)
46% identity, 91% coverage of query (215 bits)
A0A3G5E8S8 purine-nucleoside phosphorylase (EC 2.4.2.1) from Aneurinibacillus migulanus (see paper)
49% identity, 87% coverage of query (214 bits)
PndA / b2407 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
xapA / P45563 xanthosine phosphorylase (EC 2.4.2.1; EC 2.4.2.15) from Escherichia coli (strain K12) (see 15 papers)
XAPA_ECOLI / P45563 Purine nucleoside phosphorylase 2; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase II; PNP II; Xanthosine phosphorylase; EC 2.4.2.1 from Escherichia coli (strain K12) (see 7 papers)
45% identity, 92% coverage of query (211 bits)
1yqqA / P45563 Escherichia coli purine nucleoside phosphorylase ii, the product of the xapa gene (see paper)
45% identity, 92% coverage of query (211 bits)
1yr3A Escherichia coli purine nucleoside phosphorylase ii, the product of the xapa gene
45% identity, 92% coverage of query (211 bits)
8swtA / Q5LAA3 Structure of bacteroides fragilis pnp bound to transition state analog immucillin h and sulfate (see paper)
39% identity, 98% coverage of query (201 bits)
3lbaA / Q8DTU4 The crystal structure of smu.1229 from streptococcus mutans ua159 bound to hypoxanthine
45% identity, 88% coverage of query (189 bits)
4m1eB / D5SMY7 Crystal structure of purine nucleoside phosphorylase i from planctomyces limnophilus dsm 3776, nysgrc target 029364.
38% identity, 92% coverage of query (178 bits)
Q72L69 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus (see paper)
45% identity, 87% coverage of query (178 bits)
7zsqC / P9WP01 Human purine nucleoside phosphorylase in complex with js-555 (see paper)
42% identity, 98% coverage of query (171 bits)
4nsnA / B2RKN6 Crystal structure of purine nucleoside phosphorylase from porphyromonas gingivalis atcc 33277, nysgrc target 030972, orthorhombic symmetry
40% identity, 98% coverage of query (171 bits)
P9WP01 Purine nucleoside phosphorylase; PNP; Pu-NPase; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
42% identity, 98% coverage of query (171 bits)
1i80A Crystal structure of m. Tuberculosis pnp in complex with iminoribitol, 9-deazahypoxanthine and phosphate ion
42% identity, 98% coverage of query (171 bits)
3sczA Combining crystallographic, thermodynamic, and molecular dynamics studies of mycobacterium tuberculosis purine nucleoside phosphorylase
42% identity, 98% coverage of query (171 bits)
7zsqB Human purine nucleoside phosphorylase in complex with js-555
42% identity, 98% coverage of query (171 bits)
8c25A Purine nucleoside phosphorylase in complex with js-375
42% identity, 98% coverage of query (171 bits)
7zsrA Purine nucleoside phosphorylase in complex with js-379
42% identity, 98% coverage of query (171 bits)
7zsqA Human purine nucleoside phosphorylase in complex with js-555
42% identity, 98% coverage of query (171 bits)
3ix2A Crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in complex with acyclovir
42% identity, 98% coverage of query (171 bits)
3iomA Crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in complex with 2'-deoxyguanosine
42% identity, 98% coverage of query (171 bits)
1n3iA Crystal structure of mycobacterium tuberculosis pnp with transition state analog dadme-immh
42% identity, 98% coverage of query (171 bits)
1g2oA Crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in complex with a transition-state inhibitor
42% identity, 98% coverage of query (171 bits)
1fxuA Purine nucleoside phosphorylase from calf spleen in complex with n(7)- acycloguanosine inhibitor and a phosphate ion
38% identity, 93% coverage of query (169 bits)
3e0qC / Q9BMI9 Crystal structure of schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor (see paper)
39% identity, 88% coverage of query (168 bits)
Q9BMI9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Schistosoma mansoni (see 2 papers)
39% identity, 88% coverage of query (168 bits)
PNPH_ANOGA / A4Q998 Purine nucleoside phosphorylase; AgPNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Anopheles gambiae (African malaria mosquito) (see paper)
41% identity, 87% coverage of query (168 bits)
2p4sA / A4Q998 Structure of purine nucleoside phosphorylase from anopheles gambiae in complex with dadme-immh (see paper)
41% identity, 87% coverage of query (168 bits)
1a9sA Bovine purine nucleoside phosphorylase complexed with inosine and sulfate
38% identity, 93% coverage of query (168 bits)
1a9qA Bovine purine nucleoside phosphorylase complexed with inosine
38% identity, 93% coverage of query (168 bits)
1a9tA Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate
38% identity, 93% coverage of query (168 bits)
1a9oA / P55859 Bovine purine nucleoside phosphorylase complexed with phosphate (see paper)
38% identity, 93% coverage of query (167 bits)
5ko6A / A0A0U3AGT1 Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma mansoni in complex with cytosine and ribose-1-phosphate (see paper)
38% identity, 98% coverage of query (167 bits)
1a9pA Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate
38% identity, 93% coverage of query (167 bits)
5tbvA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with tubercidin
38% identity, 98% coverage of query (167 bits)
5tbuA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with hypoxanthine
38% identity, 98% coverage of query (167 bits)
5tbtA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with cytidine
38% identity, 98% coverage of query (167 bits)
6bj6A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-{[(s)- benzenesulfinyl]methyl}benzoic acid
38% identity, 98% coverage of query (167 bits)
6bifA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1-(4-amino-2-hydroxyphenyl)ethan- 1-one
38% identity, 98% coverage of query (167 bits)
6bi9A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1,2,5-trimethyl-1h-pyrrole-3- carboxylic acid
38% identity, 98% coverage of query (167 bits)
6bi1A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (2r)-2-amino-3-(benzyloxy)propan- 1-ol
38% identity, 98% coverage of query (167 bits)
6bhbA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-aminopyrimidin-5-ol
38% identity, 98% coverage of query (167 bits)
6bfvA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2- one
38% identity, 98% coverage of query (167 bits)
6bb7A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 3-methyl-1,2-dihydropyridin-2-one
38% identity, 98% coverage of query (167 bits)
6b71A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with3-(4-chlorophenyl)-5h,6h- imidazo[2,1-b][1,3]thiazole
38% identity, 98% coverage of query (167 bits)
6b56A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 5-butylpyridine-2-carboxylic acid
38% identity, 98% coverage of query (167 bits)
6b4tA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 4-methylpyridin-2-ol
38% identity, 98% coverage of query (167 bits)
6b4qA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with pyridin-4-ol
38% identity, 98% coverage of query (167 bits)
6b3lA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2,3-dihydro-1h-inden-2-amine
38% identity, 98% coverage of query (167 bits)
6b37A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 1,3-benzothiazol-2-ol
38% identity, 98% coverage of query (167 bits)
6b2lA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with piperidin-2-imine
38% identity, 98% coverage of query (167 bits)
6axaA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (3s)-5-fluoro-3-hydroxy-1,3- dihydroindol-2-one
38% identity, 98% coverage of query (167 bits)
6aweA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2- ylethylamino)benzonitrile
38% identity, 98% coverage of query (167 bits)
6bj7A Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 4-chloro-6-methylpyrimidin-2- amine
38% identity, 98% coverage of query (167 bits)
6b7iA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with (2s)-2-(3,5-difluorophenyl)-2- hydroxyacetic acid
38% identity, 98% coverage of query (167 bits)
5tbsA Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with adenine
38% identity, 98% coverage of query (167 bits)
6b6kA Crystal structure of purine nucleoside phosphorylase isoform 2 from schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3- one
38% identity, 98% coverage of query (167 bits)
P55859 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bos taurus (see 13 papers)
38% identity, 93% coverage of query (165 bits)
1b8oA Purine nucleoside phosphorylase
38% identity, 93% coverage of query (165 bits)
P55859 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Bos taurus (Bovine)
38% identity, 93% coverage of query (165 bits)
1b8nA Purine nucleoside phosphorylase
39% identity, 93% coverage of query (165 bits)
P85973 purine-nucleoside phosphorylase (EC 2.4.2.1) from Rattus norvegicus (see paper)
38% identity, 98% coverage of query (164 bits)
3d1vA / P00491 Crystal structure of human pnp complexed with 2-mercapto(3h) quinazolinone (see paper)
42% identity, 80% coverage of query (164 bits)
1lv8A Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit
42% identity, 80% coverage of query (164 bits)
4earA Crystal structure of purine nucleoside phosphorylase (w16y, w94y, w178y, h257w) mutant from human complexed with dadme-immg and phosphate
42% identity, 80% coverage of query (164 bits)
3phbE Crystal structure of human purine nucleoside phosphorylase in complex with dadme-immg
42% identity, 80% coverage of query (164 bits)
1rszA Structure of human purine nucleoside phosphorylase in complex with dadme-immucillin-h and sulfate
42% identity, 80% coverage of query (164 bits)
3k8qA Crystal structure of human purine nucleoside phosphorylase in complex with serme-immucillin h
42% identity, 80% coverage of query (164 bits)
3inyA Crystal structure of human purine nucleoside phosphorylase in complex with 7-deazaguanine
42% identity, 80% coverage of query (164 bits)
1yryE Crystal structure of human pnp complexed with mesg
42% identity, 80% coverage of query (164 bits)
1v45E Crystal structure of human pnp complexed with 3-deoxyguanosine
42% identity, 80% coverage of query (164 bits)
1v41E Crystal structure of human pnp complexed with 8-azaguanine
42% identity, 80% coverage of query (164 bits)
1v3qE Structure of human pnp complexed with ddi
42% identity, 80% coverage of query (164 bits)
1v2hE Crystal structure of human pnp complexed with guanine
42% identity, 80% coverage of query (164 bits)
1rfgE Crystal structure of human purine nucleoside phosphorylase complexed with guanosine
42% identity, 80% coverage of query (164 bits)
1rctE Crystal structure of human purine nucleoside phosphorylase complexed with inosine
42% identity, 80% coverage of query (164 bits)
1pwyE Crystal structure of human pnp complexed with acyclovir
42% identity, 80% coverage of query (164 bits)
1pf7E Crystal structure of human pnp complexed with immucillin h
42% identity, 80% coverage of query (164 bits)
3khsB / Q5YBA4 Crystal structure of grouper iridovirus purine nucleoside phosphorylase (see paper)
39% identity, 92% coverage of query (163 bits)
PNPH_MOUSE / P23492 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Mus musculus (Mouse) (see 2 papers)
42% identity, 80% coverage of query (163 bits)
PNP / P00491 purine nucleoside phosphorylase subunit (EC 2.4.2.1; EC 2.4.2.15) from Homo sapiens (see 9 papers)
PNPH_HUMAN / P00491 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Homo sapiens (Human) (see 6 papers)
P00491 purine-nucleoside phosphorylase (EC 2.4.2.1) from Homo sapiens (see 29 papers)
42% identity, 80% coverage of query (163 bits)
3k8oE Crystal structure of human purine nucleoside phosphorylase in complex with datme-immh
42% identity, 80% coverage of query (163 bits)
7zsmA Human purine nucleoside phosphorylase in complex with js-375
42% identity, 80% coverage of query (163 bits)
7zsoA Human purine nucleoside phosphorylase in complex with js-554
42% identity, 80% coverage of query (163 bits)
7zspA Human purine nucleoside phosphorylase in complex with js-555
42% identity, 80% coverage of query (163 bits)
PNPH_YEAST / Q05788 Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
41% identity, 83% coverage of query (162 bits)
7zsnA Human purine nucleoside phosphorylase in complex with js-379
42% identity, 80% coverage of query (162 bits)
PNPH_SCHPO / Q9UTG1 Putative purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
42% identity, 80% coverage of query (161 bits)
3fb1A Crystal structure of purine nucleoside phosphorylase in complex with ribose-1-phosphate
39% identity, 87% coverage of query (160 bits)
4ns1A Crystal structure of purine nucleoside phosphorylase from porphyromonas gingivalis atcc 33277, nysgrc target 30972
39% identity, 98% coverage of query (160 bits)
3fnqA Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine
38% identity, 88% coverage of query (160 bits)
3f8wA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine
38% identity, 88% coverage of query (160 bits)
3fazA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with inosine
39% identity, 87% coverage of query (160 bits)
1tcuA Crystal structure of the purine nucleoside phosphorylase from schistosoma mansoni in complex with phosphate and acetate
39% identity, 87% coverage of query (160 bits)
3e9zA Crystal structure of purine nucleoside phosphorylase from schistosoma mansoni in complex with 6-chloroguanine
38% identity, 88% coverage of query (160 bits)
3djfA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in a complex with bcx-34
38% identity, 88% coverage of query (160 bits)
3ggsA Human purine nucleoside phosphorylase double mutant e201q,n243d complexed with 2-fluoro-2'-deoxyadenosine
41% identity, 80% coverage of query (160 bits)
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Lawrence Berkeley National Laboratory