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Searching for up to 100 curated homologs for SMc04308 FitnessBrowser__Smeli:SMc04308 (271 a.a.)

Found high-coverage hits (≥70%) to 67 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

No hits had 30% identity

Change minimum %identity:

Additional hits (identity < 30%)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    24% identity, 87% coverage of query (82.8 bits)

cpoT / GB|AAB86626.1 non-heme chloroperoxidase from Streptomyces aureofaciens (see paper)
    28% identity, 85% coverage of query (81.6 bits)

P29715 bromide peroxidase (EC 1.11.1.18) from Kitasatospora aureofaciens (see 2 papers)
bpoA2 / GI|150457 non-heme bromoperoxidase BPO-A2; EC 1.11.1.- from Streptomyces aureofaciens (see 4 papers)
    28% identity, 85% coverage of query (80.1 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    23% identity, 89% coverage of query (77.8 bits)

flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
    27% identity, 83% coverage of query (76.6 bits)

5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
    25% identity, 86% coverage of query (75.9 bits)

ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
    26% identity, 88% coverage of query (75.9 bits)

3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
    26% identity, 88% coverage of query (75.9 bits)

bphD / BAM76235.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Janibacter sp. TYM3221 (see paper)
    27% identity, 93% coverage of query (75.5 bits)

dauP / Q55217 rhodomycinone D methylesterase from Streptomyces sp. (strain C5) (see 2 papers)
DNRP_STRS5 / Q55217 Rhodomycin D methylesterase DauP; 10-carbomethoxy-13-deoxycarminomycin esterase; 4-O-methylrhodomycin D methylesterase; EC 3.1.1.- from Streptomyces sp. (strain C5) (see paper)
    28% identity, 82% coverage of query (75.1 bits)

8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
    25% identity, 88% coverage of query (73.9 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    29% identity, 81% coverage of query (72.8 bits)

3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
    25% identity, 88% coverage of query (72.8 bits)

3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
    25% identity, 88% coverage of query (72.4 bits)

6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
    26% identity, 81% coverage of query (71.2 bits)

dnrP / Q54809 rhodomycinone D methyl-esterase from Streptomyces peucetius (see 3 papers)
    27% identity, 82% coverage of query (70.9 bits)

6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
    25% identity, 81% coverage of query (70.9 bits)

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    32% identity, 82% coverage of query (68.6 bits)

2ocgA / Q86WA6 Crystal structure of human valacyclovir hydrolase (see paper)
    25% identity, 87% coverage of query (68.6 bits)

2ociA Crystal structure of valacyclovir hydrolase complexed with a product analogue
    25% identity, 87% coverage of query (68.6 bits)

BPHL_HUMAN / Q86WA6 Valacyclovir hydrolase; VACVase; Valacyclovirase; Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA; EC 3.1.-.- from Homo sapiens (Human) (see 2 papers)
    25% identity, 92% coverage of query (68.2 bits)

6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
    24% identity, 81% coverage of query (67.8 bits)

1hl7A / Q8GJP7 Gamma lactamase from an aureobacterium species in complex with 3a,4,7, 7a-tetrahydro-benzo [1,3] dioxol-2-one (see paper)
    26% identity, 85% coverage of query (67.4 bits)

tesD / Q83VZ6 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase (EC 3.7.1.17) from Comamonas testosteroni (see 3 papers)
    25% identity, 86% coverage of query (67.0 bits)

MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
    25% identity, 85% coverage of query (66.2 bits)

hppC / AAB81313.1 2-hydroxy-6-ketonona-2,4-dienoate hydrolase from Rhodococcus globerulus (see paper)
    24% identity, 89% coverage of query (65.1 bits)

catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
    27% identity, 85% coverage of query (65.1 bits)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    27% identity, 88% coverage of query (65.1 bits)

DCH_ACICA / Q83WC8 Bifunctional esterase/perhydrolase DCH; 3,4-dihydrocoumarin hydrolase; DCH; Metal-free haloperoxidase; EC 3.1.1.35 from Acinetobacter calcoaceticus (see 3 papers)
Q83WC8 dihydrocoumarin hydrolase (EC 3.1.1.35) from Acinetobacter calcoaceticus (see paper)
    27% identity, 88% coverage of query (64.7 bits)

Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
    32% identity, 82% coverage of query (64.3 bits)

E3SVS0 amidase (EC 3.5.1.4) from Microbacterium hydrocarbonoxydans (see paper)
    24% identity, 86% coverage of query (63.9 bits)

2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
    28% identity, 88% coverage of query (63.5 bits)

Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
    28% identity, 88% coverage of query (63.2 bits)

Q3HWU8 carboxylesterase (EC 3.1.1.1) from Pseudomonas putida (see paper)
    27% identity, 86% coverage of query (62.0 bits)

cpoL / PDB|1A88_A non-heme chloroperoxidase; EC 1.11.1.10 from Streptomyces lividans (see 2 papers)
cpoL / AAA18642.1 chloroperoxidase from Streptomyces lividans (see paper)
    26% identity, 86% coverage of query (62.0 bits)

MHPC_COMTE / Q8KZP5 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
    25% identity, 85% coverage of query (61.6 bits)

B5SU85 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Dyella ginsengisoli (see paper)
    27% identity, 85% coverage of query (60.8 bits)

nahN / BAE92169.1 2-hydroxymuconic semialdehyde hydrolase NahN from Pseudomonas putida (see 2 papers)
    27% identity, 84% coverage of query (60.8 bits)

cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
    23% identity, 87% coverage of query (60.1 bits)

pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
    28% identity, 72% coverage of query (58.2 bits)

5aljA / P34913 Ligand complex structure of soluble epoxide hydrolase (see paper)
    22% identity, 90% coverage of query (57.0 bits)

rdmC / Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see 2 papers)
RDMC_STREF / Q54528 Aclacinomycin methylesterase RdmC; EC 3.1.1.95 from Streptomyces purpurascens (see 3 papers)
Q54528 aclacinomycin methylesterase (EC 3.1.1.95) from Streptomyces purpurascens (see paper)
    27% identity, 79% coverage of query (57.0 bits)

1q0rA / Q54528 Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin t (dcmat) (see paper)
    27% identity, 79% coverage of query (57.0 bits)

1q0zA Crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin a (dcma)
    27% identity, 79% coverage of query (57.0 bits)

G3KFX4 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas sp. (see paper)
    26% identity, 86% coverage of query (55.8 bits)

BPOC_MYCTU / P9WNH1 Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    25% identity, 85% coverage of query (55.5 bits)

BPHD_PSES1 / P17548 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Pseudomonas sp. (strain KKS102) (see paper)
    24% identity, 85% coverage of query (55.5 bits)

BPHD_PSEFK / Q52011 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Pseudomonas furukawaii (see paper)
bphD / BAA12881.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase from Pseudomonas oleovorans (see paper)
    26% identity, 89% coverage of query (54.3 bits)

BPHD_PARXL / P47229 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Paraburkholderia xenovorans (strain LB400) (see 2 papers)
P47229 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Paraburkholderia xenovorans (see 2 papers)
BphD / CAA46911.1 2-hydroxy-6-oxo-6-phenylhexa-2, 4-dienoate hydrolase from Pseudomonas sp (see paper)
    26% identity, 89% coverage of query (54.3 bits)

bphD / BAA25612.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus erythropolis (see paper)
    24% identity, 87% coverage of query (54.3 bits)

2og1A / P47229 Crystal structure of bphd, a c-c hydrolase from burkholderia xenovorans lb400 (see paper)
    26% identity, 89% coverage of query (53.9 bits)

7c4dA / A0A2S1GUX0 Marine microorganism esterase (see paper)
    23% identity, 82% coverage of query (53.5 bits)

2rhwA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with 3,10-di-fluoro hopda
    25% identity, 89% coverage of query (52.8 bits)

2rhtA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with 3-cl hopda
    25% identity, 89% coverage of query (52.8 bits)

2puhA Crystal structure of the s112a mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with its substrate hopda
    25% identity, 89% coverage of query (52.8 bits)

2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
    23% identity, 85% coverage of query (51.2 bits)

1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
    23% identity, 85% coverage of query (50.4 bits)

1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
    23% identity, 85% coverage of query (50.4 bits)

1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
    23% identity, 85% coverage of query (50.4 bits)

1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
    23% identity, 85% coverage of query (50.4 bits)

1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
    23% identity, 85% coverage of query (50.4 bits)

1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
    23% identity, 85% coverage of query (50.4 bits)

RSBQ_BACSU / O07015 Sigma factor SigB regulation protein RsbQ from Bacillus subtilis (strain 168) (see 2 papers)
    24% identity, 79% coverage of query (48.9 bits)

2pujA Crystal structure of the s112a/h265a double mutant of a c-c hydrolase, bphd from burkholderia xenovorans lb400, in complex with its substrate hopda
    25% identity, 89% coverage of query (48.9 bits)

carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
    24% identity, 92% coverage of query (47.8 bits)

5z7wB / A0A0M4AV81 Crystal structure of striga hermonthica htl1 (shhtl1) (see paper)
    25% identity, 81% coverage of query (44.7 bits)

5frdA / O28735 Structure of a thermophilic esterase (see paper)
    23% identity, 90% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory