Searching for up to 100 curated homologs for Synpcc7942_0278 FitnessBrowser__SynE:Synpcc7942_0278 (165 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
Removed hits that are identical to the query, leaving 43
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q6XQK5 hydrogen dehydrogenase (EC 1.12.1.2) from Thiocapsa roseopersicina (see paper)
49% identity, 92% coverage of query (156 bits)
K0B468 formate dehydrogenase (NAD+, ferredoxin) (subunit 1/4) (EC 1.17.1.11) from Gottschalkia acidurici (see paper)
40% identity, 90% coverage of query (131 bits)
8a6tC / A0A097ATI0 Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from thermoanaerobacter kivui in the reduced state (see paper)
40% identity, 91% coverage of query (128 bits)
8a5eC / H6LFG7 Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from acetobacterium woodii in the reduced state (see paper)
50% identity, 71% coverage of query (127 bits)
7t2rC / I4BYB8 Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn-free apo state (see paper)
45% identity, 80% coverage of query (122 bits)
HNDA_SOLFR / Q46505 NADP-reducing hydrogenase subunit HndA; Hydrogen dehydrogenase (NADP(+)); EC 1.12.1.3 from Solidesulfovibrio fructosivorans (Desulfovibrio fructosivorans) (see 3 papers)
39% identity, 82% coverage of query (118 bits)
8oh5A / A0A0U1KYW8 Cryo-em structure of the electron bifurcating transhydrogenase stnabc complex from sporomusa ovata (state 2) (see paper)
42% identity, 86% coverage of query (117 bits)
B2BSJ7 NAD(P)H sulfur oxidoreductase (CoA-dependent) (subunit 4/4) (EC 1.8.1.18) from Thermococcus litoralis (see paper)
38% identity, 82% coverage of query (115 bits)
hydC / O52681 hydrogenase γ subunit (EC 1.12.1.4) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
HYDC_THEMA / O52681 Bifurcating [FeFe] hydrogenase gamma subunit; Hydrogenase (NAD(+), ferredoxin) gamma subunit; Iron-hydrogenase gamma subunit; EC 1.12.1.4 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
35% identity, 90% coverage of query (115 bits)
7p5hC / O52681 Tmhydabc- d2 map (see paper)
35% identity, 90% coverage of query (114 bits)
hytC / S5ZJ59 hydrogenase (NADP+,ferredoxin) γ subunit from Clostridium autoethanogenum DSM 10061 (see paper)
36% identity, 93% coverage of query (107 bits)
TC 3.D.1.5.1 / Q74GA4 NuoE aka GSU0342, component of Proton-translocating NADH dehydrogenase I from Geobacter sulfurreducens (see paper)
38% identity, 80% coverage of query (105 bits)
8b9zE / Q9VX36 Drosophila melanogaster complex i in the active state (dm1) (see paper)
36% identity, 85% coverage of query (99.4 bits)
8eswV2 NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A
36% identity, 85% coverage of query (99.4 bits)
6r7pA / O66842 Crystal structure of oxidized aquifex aeolicus nadh-quinone oxidoreductase subunits nuoe and nuof s96m (see paper)
34% identity, 87% coverage of query (97.1 bits)
5gupE / F1SM98 structure of mammalian respiratory supercomplex I1III2IV1 (see paper)
37% identity, 75% coverage of query (90.5 bits)
NDUV2_MOUSE / Q9D6J6 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Mus musculus (Mouse) (see paper)
39% identity, 75% coverage of query (90.5 bits)
P9WIV5 NADH-quinone oxidoreductase subunit E; NADH dehydrogenase I subunit E; NDH-1 subunit E; EC 7.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
36% identity, 87% coverage of query (90.1 bits)
7dgq9 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
37% identity, 75% coverage of query (90.1 bits)
NDUFV2 / P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial from Homo sapiens (see 4 papers)
NDUV2_HUMAN / P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NDUFV2; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Homo sapiens (Human) (see 4 papers)
37% identity, 75% coverage of query (89.7 bits)
NDUV2_BOVIN / P04394 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH dehydrogenase subunit II; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Bos taurus (Bovine) (see 4 papers)
TC 3.D.1.6.1 / P04394 24 (NuoE), component of The vertebrate H+-translocating NADH dehydrogenase (NDH) complex (45 subunits) from Bos taurus (Bovine) (see 3 papers)
37% identity, 75% coverage of query (89.4 bits)
7v2cO / A0A287BG40 Active state complex i from q10 dataset (see paper)
37% identity, 75% coverage of query (89.4 bits)
8e9gE / A0QU32 Mycobacterial respiratory complex i with both quinone positions modelled (see paper)
34% identity, 90% coverage of query (88.6 bits)
7b0nE / Q9UUT9 3.7-angstrom structure of Yarrowia lipolytica complex I with an R121M mutation in NUCM. (see paper)
34% identity, 78% coverage of query (87.8 bits)
6tg9G / D5AQH2 Cryo-em structure of nadh reduced form of NAD+-dependent formate dehydrogenase from rhodobacter capsulatus (see paper)
36% identity, 87% coverage of query (87.0 bits)
fdsG / GI|3724143 NAD-dependent formate dehydrogenase, gamma subunit from Ralstonia eutropha H16 (see paper)
39% identity, 71% coverage of query (86.3 bits)
Build an alignment for Synpcc7942_0278 and 26 homologs with ≥ 30% identity
Or download the sequences
orf19.2091 potential mitochondrial complex I, NUHM_24kd subunit from Candida albicans (see paper)
29% identity, 97% coverage of query (85.9 bits)
6vw8C / Q0KDY3 Formate dehydrogenase fdsabg subcomplex fdsbg from c. Necator (see paper)
39% identity, 71% coverage of query (85.5 bits)
TC 3.D.1.6.2 / P40915 24 (NuoE), component of The fungal H+ translocating NADH dehydrogenase (NDH) complex (38 subunits; 35 included here) from Neurospora crassa (see 3 papers)
33% identity, 88% coverage of query (84.7 bits)
7zmbH / G0SDM6 Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 2) (see paper)
31% identity, 99% coverage of query (83.6 bits)
nuoE / Q88FH4 NADH-quinone oxidoreductasesubunit E (EC 7.1.1.2) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
34% identity, 79% coverage of query (80.5 bits)
Q84FW3 formate dehydrogenase (EC 1.17.1.9) from Methylorubrum extorquens (see paper)
33% identity, 75% coverage of query (75.5 bits)
NuoE / b2285 NADH:quinone oxidoreductase subunit E from Escherichia coli K-12 substr. MG1655 (see 15 papers)
nuoE / P0AFD1 NADH:quinone oxidoreductase subunit E from Escherichia coli (strain K12) (see 17 papers)
TC 3.D.1.1.1 / P0AFD1 NUOE aka B2285, component of NADH dehydrogenase I, NuoA-N from Escherichia coli (see 6 papers)
nuoE / RF|NP_416788 NDH-1 subunit E; EC 1.6.99.5 from Escherichia coli K12 (see 9 papers)
32% identity, 80% coverage of query (75.5 bits)
7awtE / P0AFD1 E. Coli nadh quinone oxidoreductase hydrophilic arm (see paper)
32% identity, 80% coverage of query (75.5 bits)
TC 3.D.1.6.4 / Q6V9B3 27 (NuoE), component of The green algal H+ translocating NADH dehydrogenase (NDH) complex (42 subunits; 33 included here) from Chlamydomonas reinhardtii (see paper)
34% identity, 76% coverage of query (75.1 bits)
hoxF / P22317 α subunit from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
P22317 hydrogen dehydrogenase (EC 1.12.1.2) from Cupriavidus necator (see paper)
32% identity, 76% coverage of query (72.8 bits)
TC 3.D.1.2.1 / P29914 NQO2, component of NADH dehydrogenase I from Paracoccus denitrificans (see 2 papers)
NQO2 / AAA25588.1 NADH dehydrogenase from Paracoccus denitrificans (see paper)
28% identity, 78% coverage of query (65.5 bits)
P29914 NADH-quinone oxidoreductase chain 2; NADH dehydrogenase I, chain 2; NDH-1, chain 2; EC 7.1.1.- from Paracoccus denitrificans
28% identity, 78% coverage of query (65.5 bits)
K0AXR5 formate dehydrogenase (NAD+, ferredoxin) (subunit 3/4) (EC 1.17.1.11) from Gottschalkia acidurici (see paper)
30% identity, 82% coverage of query (62.8 bits)
5xfaA / A0A077L6X8 Crystal structure of NAD+-reducing [nife]-hydrogenase in the h2- reduced state (see paper)
29% identity, 80% coverage of query (59.7 bits)
5xf9A Crystal structure of NAD+-reducing [nife]-hydrogenase in the air- oxidized state
29% identity, 80% coverage of query (59.7 bits)
fdh1B / Q8KTI8 NAD-dependent formate dehydrogenase β subunit (EC 1.17.1.9) from Methylorubrum extorquens (see 2 papers)
Q8KTI8 formate dehydrogenase (EC 1.17.1.9) from Methylorubrum extorquens (see paper)
28% identity, 95% coverage of query (54.7 bits)
7vw6B / C5ATT6 Cryo-em structure of formate dehydrogenase 1 from methylorubrum extorquens am1 (see paper)
28% identity, 95% coverage of query (54.7 bits)
Or start over
Lawrence Berkeley National Laboratory