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Searching for up to 100 curated homologs for Synpcc7942_0369 FitnessBrowser__SynE:Synpcc7942_0369 (484 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

8p84B X-ray structure of thermoanaerobacterales bacterium monoamine oxidase (see paper)
    41% identity, 93% coverage of query (315 bits)

3rhaA / A1R0W1 The crystal structure of oxidoreductase from arthrobacter aurescens
    36% identity, 92% coverage of query (281 bits)

2yg3B / B0F9F6 Structure-based redesign of cofactor binding in putrescine oxidase: wild type enzyme (see paper)
    37% identity, 92% coverage of query (280 bits)

2yg4A Structure-based redesign of cofactor binding in putrescine oxidase: wild type bound to putrescine
    37% identity, 92% coverage of query (280 bits)

AOFB_MOUSE / Q8BW75 Amine oxidase [flavin-containing] B; Monoamine oxidase type B; MAO-B; EC 1.4.3.21; EC 1.4.3.4 from Mus musculus (Mouse) (see paper)
Q8BW75 monoamine oxidase (EC 1.4.3.4) from Mus musculus (see 4 papers)
    34% identity, 93% coverage of query (268 bits)

AOFB_RAT / P19643 Amine oxidase [flavin-containing] B; Monoamine oxidase type B; MAO-B; EC 1.4.3.21; EC 1.4.3.4 from Rattus norvegicus (Rat) (see 2 papers)
P19643 monoamine oxidase (EC 1.4.3.4) from Rattus norvegicus (see 26 papers)
    35% identity, 93% coverage of query (267 bits)

Q6Q2J0 monoamine oxidase (EC 1.4.3.4) from Sus scrofa (see paper)
    33% identity, 94% coverage of query (266 bits)

MAOA / P21397 amine oxidase A (EC 1.4.3.4) from Homo sapiens (see 4 papers)
AOFA_HUMAN / P21397 Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A; EC 1.4.3.21; EC 1.4.3.4 from Homo sapiens (Human) (see 7 papers)
P21397 monoamine oxidase (EC 1.4.3.4) from Homo sapiens (see 58 papers)
    33% identity, 92% coverage of query (266 bits)

2z5xA / P21397 Crystal structure of human monoamine oxidase a with harmine (see paper)
    33% identity, 92% coverage of query (266 bits)

LAADH_SYNY3 / Q55629 L-amino acid dehydrogenase; L-amino acid:plastoquinone oxidoreductase; L-arginine dehydrogenase; EC 1.4.5.- from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
Q55629 L-amino-acid dehydrogenase (EC 1.4.1.5) from Synechocystis sp. (see paper)
    33% identity, 95% coverage of query (264 bits)

AOFA_MOUSE / Q64133 Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A; EC 1.4.3.21; EC 1.4.3.4 from Mus musculus (Mouse) (see paper)
Q64133 monoamine oxidase (EC 1.4.3.4) from Mus musculus (see 5 papers)
    33% identity, 92% coverage of query (263 bits)

P21398 monoamine oxidase (EC 1.4.3.4) from Bos taurus (see 5 papers)
    33% identity, 92% coverage of query (261 bits)

1o5wC / P21396 The structure basis of specific recognitions for substrates and inhibitors of rat monoamine oxidase a (see paper)
    33% identity, 92% coverage of query (261 bits)

AOF_DANRE / Q6NSN2 Amine oxidase [flavin-containing]; Monoamine oxidase; MAO; Z-MAO; EC 1.4.3.21; EC 1.4.3.4 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 2 papers)
Q6NSN2 monoamine oxidase (EC 1.4.3.4) from Danio rerio (see 2 papers)
    33% identity, 92% coverage of query (260 bits)

2bxrA Human monoamine oxidase a in complex with clorgyline, crystal form a
    33% identity, 92% coverage of query (260 bits)

puo / P40974 putrescine oxidase subunit (EC 1.4.3.10) from Kocuria rosea (see 2 papers)
    36% identity, 94% coverage of query (258 bits)

MAOB / P27338 monoamine oxidase B subunit (EC 1.4.3.21; EC 1.4.3.4) from Homo sapiens (see paper)
AOFB_HUMAN / P27338 Amine oxidase [flavin-containing] B; Monoamine oxidase type B; MAO-B; EC 1.4.3.21; EC 1.4.3.4 from Homo sapiens (Human) (see 10 papers)
P27338 monoamine oxidase (EC 1.4.3.4) from Homo sapiens (see 55 papers)
    35% identity, 93% coverage of query (253 bits)

6fvzA / P27338 Crystal structure of human monoamine oxidase b (mao b) in complex with dimethylphenyl-chromone-carboxamide (see paper)
    35% identity, 93% coverage of query (252 bits)

7zw3AAA Amine oxidase [flavin-containing] B
    35% identity, 93% coverage of query (252 bits)

6yt2A Crystal structure of human monoamine oxidase b in complex with diphenylene iodonium (dpi)
    35% identity, 93% coverage of query (252 bits)

6fw0A Crystal structure of human monoamine oxidase b (mao b) in complex with chlorophenyl-chromone-carboxamide
    35% identity, 93% coverage of query (252 bits)

7b0zA Crystal structure of human monoamine oxidase b in complex with (e)-3- phenyl-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one
    35% identity, 93% coverage of query (252 bits)

7b0vA Crystal structure of human monoamine oxidase b in complex with (e)-3- phenyl-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one
    35% identity, 93% coverage of query (252 bits)

3zyxA Crystal structure of human monoamine oxidase b in complex with methylene blue and bearing the double mutation i199a-y326a
    34% identity, 93% coverage of query (251 bits)

7p4hA Crystal structure of monoamine oxidase b in complex with inhibitor (+)-2
    34% identity, 93% coverage of query (251 bits)

7p4fA Crystal structure of monoamine oxidase b in complex with inhibitor 1
    34% identity, 93% coverage of query (251 bits)

6rleA Crystal structure of human monoamine oxidase b in complex with styrylpiperidine analogue 97
    34% identity, 93% coverage of query (251 bits)

6rkpA Crystal structure of human monoamine oxidase b in complex with styrylpiperidine analogue 84
    34% identity, 93% coverage of query (251 bits)

6rkbA Crystal structure of human monoamine oxidase b in complex with styrylpiperidine analogue 1
    34% identity, 93% coverage of query (251 bits)

6fwcA Crystal structure of human monoamine oxidase b (mao b) in complex with fluorophenyl-chromone-carboxamide
    34% identity, 93% coverage of query (251 bits)

5mrlA Crystal structure of human monoamine oxidase b (mao b) in complex with n(furan2ylmethyl)nmethylprop2yn1amine (f2mpa)
    34% identity, 93% coverage of query (251 bits)

4crtA Crystal structure of human monoamine oxidase b in complex with the multi-target inhibitor ass234
    34% identity, 93% coverage of query (251 bits)

4a7aA Crystal structure of human monoamine oxidase b (mao b) in complex with rosiglitazone
    34% identity, 93% coverage of query (251 bits)

4a79A Crystal structure of human monoamine oxidase b (mao b) in complex with pioglitazone
    34% identity, 93% coverage of query (251 bits)

3po7A Human monoamine oxidase b in complex with zonisamide
    34% identity, 93% coverage of query (251 bits)

2xcgA Tranylcypromine-inhibited human monoamine oxidase b in complex with 2- (2-benzofuranyl)-2-imidazoline
    34% identity, 93% coverage of query (251 bits)

2vz2A Human mao b in complex with mofegiline
    34% identity, 93% coverage of query (251 bits)

2vrmA Structure of human mao b in complex with phenyethylhydrazine
    34% identity, 93% coverage of query (251 bits)

2v61A Structure of human mao b in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-(methylamino)methyl-coumarin
    34% identity, 93% coverage of query (251 bits)

2v60A Structure of human mao b in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-carboxaldehyde-coumarin
    34% identity, 93% coverage of query (251 bits)

2v5zA Structure of human mao b in complex with the selective inhibitor safinamide
    34% identity, 93% coverage of query (251 bits)

2c70A Functional role of the aromatic cage in human monoamine oxidase b: structures and catalytic properties of tyr435 mutant proteins
    34% identity, 93% coverage of query (251 bits)

2c67A Mao inhibition by rasagiline analogues
    34% identity, 93% coverage of query (251 bits)

2c66A Mao inhibition by rasagiline analogues
    34% identity, 93% coverage of query (251 bits)

2c65A Mao inhibition by rasagiline analogues
    34% identity, 93% coverage of query (251 bits)

2bybA Human monoamine oxidase b in complex with deprenyl
    34% identity, 93% coverage of query (251 bits)

2bk3A Human monoamine oxidase b in complex with farnesol
    34% identity, 93% coverage of query (251 bits)

1s3eA Crystal structure of maob in complex with 6-hydroxy-n- propargyl-1(r)-aminoindan
    34% identity, 93% coverage of query (251 bits)

1s3bA Crystal structure of maob in complex with n-methyl-n- propargyl-1(r)-aminoindan
    34% identity, 93% coverage of query (251 bits)

1s2yA Crystal structure of maob in complex with n-propargyl-1(s)- aminoindan
    34% identity, 93% coverage of query (251 bits)

1s2qA Crystal structure of maob in complex with n-propargyl-1(r)-aminoindan (rasagiline)
    34% identity, 93% coverage of query (251 bits)

1ojcA Human monoamine oxidase b in complex with n-(2-aminoethyl)-p-chlorobenzamide
    34% identity, 93% coverage of query (251 bits)

1ojaA Human monoamine oxidase b in complex with isatin
    34% identity, 93% coverage of query (251 bits)

1oj9A Human monoamine oxidase b in complex with 1,4-diphenyl-2-butene
    34% identity, 93% coverage of query (251 bits)

2c64B Mao inhibition by rasagiline analogues
    34% identity, 93% coverage of query (250 bits)

1gosA Human monoamine oxidase b
    35% identity, 93% coverage of query (250 bits)

AOFB_BOVIN / P56560 Amine oxidase [flavin-containing] B; Monoamine oxidase type B; MAO-B; EC 1.4.3.21; EC 1.4.3.4 from Bos taurus (Bovine) (see 3 papers)
P56560 monoamine oxidase (EC 1.4.3.4) from Bos taurus (see 9 papers)
    34% identity, 93% coverage of query (247 bits)

Maoa / P21396 monoamine oxidase A subunit (EC 1.4.3.4) from Rattus norvegicus (see 4 papers)
AOFA_RAT / P21396 Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A; EC 1.4.3.21; EC 1.4.3.4 from Rattus norvegicus (Rat) (see 4 papers)
P21396 monoamine oxidase (EC 1.4.3.4) from Rattus norvegicus (see 29 papers)
    33% identity, 90% coverage of query (243 bits)

6lqcA Crystal structure of cyclohexylamine oxidase from erythrobacteraceae bacterium (see paper)
    33% identity, 93% coverage of query (240 bits)

6lqlA Complex structure of chao with product from erythrobacteraceae bacterium
    33% identity, 93% coverage of query (240 bits)

M5AWH1 cyclohexylamine oxidase (EC 1.4.3.12) from Microbacterium oxydans (see paper)
    31% identity, 94% coverage of query (228 bits)

4i58A / R4GRV2 Cyclohexylamine oxidase from brevibacterium oxydans ih-35a (see paper)
    32% identity, 91% coverage of query (226 bits)

Build an alignment

Build an alignment for Synpcc7942_0369 and 62 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

LDL1_ARATH / Q8VXV7 Lysine-specific histone demethylase 1 homolog 1; Lysine-specific histone demethylase 1C; Flavin-containing amine oxidase domain-containing protein 1; Protein LSD1-LIKE 1; AtLSD1; Protein SWIRM-PAO 1; AtSWP1; EC 1.-.-.- from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q8VXV7 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase (EC 1.14.99.66) from Arabidopsis thaliana (see paper)
    28% identity, 92% coverage of query (115 bits)

2vvmA / P46882 The structure of mao-n-d5, a variant of monoamine oxidase from aspergillus niger. (see paper)
    26% identity, 92% coverage of query (105 bits)

FLD_ARATH / Q9CAE3 Protein FLOWERING LOCUS D; Protein SUPPRESSOR OF OVEREXPRESSED FCA 1; EC 1.-.-.- from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
    27% identity, 92% coverage of query (102 bits)

PNAO_PSESP / H8ZPX1 Pseudooxynicotine dehydrogenase; Pseudooxynicotine amine oxidase; PNAO; EC 1.4.2.3 from Pseudomonas sp. (see paper)
H8ZPX1 pseudooxynicotine oxidase (EC 1.4.3.24) from Pseudomonas sp. (see paper)
    25% identity, 92% coverage of query (102 bits)

P46882 monoamine oxidase (EC 1.4.3.4) from Aspergillus niger (see paper)
    26% identity, 98% coverage of query (101 bits)

PNAO_PSEP6 / F8G0P1 Pseudooxynicotine dehydrogenase; Pon amine dehydrogenase; Pseudooxynicotine amine oxidase; Pnao; EC 1.4.2.3 from Pseudomonas putida (strain DSM 28022 / S16) (see 3 papers)
    24% identity, 99% coverage of query (100 bits)

P72346 L-amino-acid oxidase (EC 1.4.3.2); L-arginine oxidase (EC 1.4.3.25) from Synechococcus elongatus PCC 6301 (see paper)
    26% identity, 99% coverage of query (97.1 bits)

KDM1B / Q8NB78 lysine-specific histone demethylase 1B (EC 1.14.99.66) from Homo sapiens (see 2 papers)
KDM1B_HUMAN / Q8NB78 Lysine-specific histone demethylase 2; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 1B; EC 1.14.99.66 from Homo sapiens (Human) (see 4 papers)
    26% identity, 92% coverage of query (94.0 bits)

7xe1A / Q8NB78 Crystal structure of lsd2 in complex with cis-4-br-pcpa
    26% identity, 92% coverage of query (93.6 bits)

6r25K Structure of lsd2/npac-linker/nucleosome core particle complex: class 3
    26% identity, 92% coverage of query (93.6 bits)

4guuA Crystal structure of lsd2-npac with tranylcypromine
    26% identity, 92% coverage of query (93.6 bits)

7xe3A Crystal structure of lsd2 in complex with cis-4-br-2,5-f2-pcpa (s1024)
    26% identity, 92% coverage of query (93.6 bits)

4fwfA Complex structure of lsd2/aof1/kdm1b with h3k4 mimic
    26% identity, 92% coverage of query (93.6 bits)

A1IGW6 L-amino-acid oxidase (EC 1.4.3.2) from Sebastes schlegelii (see paper)
    25% identity, 93% coverage of query (93.2 bits)

D2KWB6 L-amino-acid oxidase (EC 1.4.3.2) from Platichthys stellatus (see 3 papers)
    23% identity, 92% coverage of query (93.2 bits)

7u6lD / F8G0P1 Pseudooxynicotine amine oxidase (see paper)
    23% identity, 92% coverage of query (91.3 bits)

B5U982 L-amino-acid oxidase (EC 1.4.3.2) from Myoxocephalus polyacanthocephalus (see paper)
    26% identity, 92% coverage of query (90.9 bits)

OXLA_SIGCA / P86810 L-amino-acid oxidase; Antiparasitic protein; APP; Serum L-amino-acid oxidase; SR-LAAO; EC 1.4.3.2 from Siganus canaliculatus (White-spotted spinefoot) (Chaetodon canaliculatus) (see 2 papers)
P86810 L-amino-acid oxidase (EC 1.4.3.2) from Siganus canaliculatus (see 2 papers)
    25% identity, 93% coverage of query (90.9 bits)

staO / Q83WG4 L-amino acid oxidase (EC 1.4.3.23) from Streptomyces sp. TP-A0274 (see paper)
    25% identity, 92% coverage of query (90.5 bits)

PAO3 / Q9LYT1 non-specific polyamine oxidase (EC 1.5.3.17) from Arabidopsis thaliana (see paper)
PAO3_ARATH / Q9LYT1 Polyamine oxidase 3; AtPAO3; EC 1.5.3.17 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9LYT1 non-specific polyamine oxidase (EC 1.5.3.17) from Arabidopsis thaliana (see 7 papers)
    25% identity, 93% coverage of query (87.8 bits)

6cr0A / A0A075BSX9 1.55 a resolution structure of (s)-6-hydroxynicotine oxidase from shinella hzn7
    24% identity, 92% coverage of query (87.4 bits)

nctB / A0A075BSX9 (S)-6-hydroxynicotine oxidase (EC 1.5.3.5) from Shinella sp. (strain HZN7) (see 2 papers)
HLNO_SHIS7 / A0A075BSX9 (S)-6-hydroxynicotine oxidase; (S)-6HN oxidase; 6-hydroxy-L-nicotine oxidase; 6-HLNO; L-hydroxynicotine oxidase; LHNO; EC 1.5.3.5 from Shinella sp. (strain HZN7) (see 2 papers)
A0A075BSX9 (S)-6-hydroxynicotine oxidase (EC 1.5.3.5) from Shinella sp. (see paper)
A0A075XFI8 (S)-6-hydroxynicotine oxidase (EC 1.5.3.5) from Ochrobactrum sp. SJY1 (see paper)
    24% identity, 92% coverage of query (87.4 bits)

PAO4_ORYSJ / Q7XR46 Polyamine oxidase 4; OsPAO4; EC 1.5.3.- from Oryza sativa subsp. japonica (Rice) (see paper)
    26% identity, 91% coverage of query (87.0 bits)

PAO4 / Q8H191 spermine oxidase (EC 1.5.3.17) from Arabidopsis thaliana (see paper)
PAO4_ARATH / Q8H191 Probable polyamine oxidase 4; AtPAO4; Amine oxidase 2; EC 1.5.3.16 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q8H191 spermine oxidase (EC 1.5.3.16) from Arabidopsis thaliana (see 4 papers)
    24% identity, 94% coverage of query (86.7 bits)

OXLA_MICMP / A0A2U8QPE6 L-amino acid oxidase; LAO; MipLAAO1; EC 1.4.3.2 from Micrurus mipartitus (Red-tailed coral snake) (see 2 papers)
A0A2U8QPE6 L-amino-acid oxidase (EC 1.4.3.2) from Micrurus mipartitus (see paper)
    24% identity, 94% coverage of query (84.7 bits)

A0A0C6EYL8 L-amino-acid oxidase (EC 1.4.3.2) from Gadus morhua (see paper)
    25% identity, 92% coverage of query (84.0 bits)

KDM1B_MOUSE / Q8CIG3 Lysine-specific histone demethylase 1B; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 2; EC 1.14.99.66 from Mus musculus (Mouse) (see 2 papers)
Q8CIG3 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase (EC 1.14.99.66) from Mus musculus (see paper)
    26% identity, 92% coverage of query (84.0 bits)

A8QL51 L-amino-acid oxidase (EC 1.4.3.2) from Bungarus multicinctus (see 2 papers)
    23% identity, 98% coverage of query (83.6 bits)

8eegB / A0A807MR40 C. Ammoniagenes monoamine oxidase (mao) bound to dopamine (see paper)
    27% identity, 92% coverage of query (83.2 bits)

8eemA C. Ammoniagenes monoamine oxidase (mao) bound to norepinephrine
    27% identity, 92% coverage of query (83.2 bits)

8eelA C. Ammoniagenes monoamine oxidase (mao) bound to 5-aminopentanol
    27% identity, 92% coverage of query (83.2 bits)

PAO3_ORYSJ / Q7X809 Polyamine oxidase 3; OsPAO3; EC 1.5.3.- from Oryza sativa subsp. japonica (Rice) (see paper)
    24% identity, 93% coverage of query (82.8 bits)

OXLA_NAJAT / A8QL58 L-amino-acid oxidase; LAO; NA-LAAO; EC 1.4.3.2 from Naja atra (Chinese cobra) (see paper)
    23% identity, 98% coverage of query (81.6 bits)

5z2gA / A8QL58 Crystal structure of l-amino acid oxidase from venom of naja atra
    23% identity, 94% coverage of query (81.3 bits)

PAO2_ARATH / Q9SKX5 Polyamine oxidase 2; AtPAO2; Amine oxidase 1; EC 1.5.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9SKX5 non-specific polyamine oxidase (EC 1.5.3.17) from Arabidopsis thaliana (see 6 papers)
    26% identity, 89% coverage of query (80.1 bits)

MPAO / O64411 polyamine oxidase (propane-1,3-diamine forming) (EC 1.5.3.14) from Zea mays (see 3 papers)
PAO1_MAIZE / O64411 Polyamine oxidase 1; EC 1.5.3.14; EC 1.5.3.15 from Zea mays (Maize) (see 2 papers)
O64411 polyamine oxidase (propane-1,3-diamine-forming) (EC 1.5.3.14) from Zea mays (see 8 papers)
    23% identity, 92% coverage of query (78.6 bits)

OXLA_LACMT / J7H670 L-amino acid oxidase Lm29; LmLAAO; LAO; EC 1.4.3.2 from Lachesis muta (South American bushmaster) (see paper)
    22% identity, 93% coverage of query (78.6 bits)

1h84A Covalent adduct between polyamine oxidase and n1ethyln11((cycloheptyl)methyl)4,8diazaundecane at ph 4.6
    23% identity, 92% coverage of query (78.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory