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Searching for up to 100 curated homologs for Synpcc7942_0645 Synpcc7942_0645 glutamate-1-semialdehyde aminotransferase (453 a.a.)

Found high-coverage hits (≥70%) to 91 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

P24630 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Synechococcus sp. (see 2 papers)
    100% identity, 96% coverage of query (884 bits)

2gsaB Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
    99% identity, 94% coverage of query (866 bits)

2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form)
    99% identity, 94% coverage of query (866 bits)

3fq7A / P24630 Gabaculine complex of gsam (see paper)
    99% identity, 94% coverage of query (865 bits)

3usfA Crystal structure of dava-4
    99% identity, 94% coverage of query (865 bits)

2hp2A Inter-subunit signaling in gsam
    99% identity, 94% coverage of query (865 bits)

2hp1A Inter-subunit signaling in gsam
    99% identity, 94% coverage of query (865 bits)

2hozA Inter-subunit signaling in gsam
    99% identity, 94% coverage of query (865 bits)

3fqaA Gabaculien complex of gabaculine resistant gsam version
    99% identity, 94% coverage of query (862 bits)

3usfB / Q31QJ2 Crystal structure of dava-4
    93% identity, 94% coverage of query (807 bits)

2hp1B Inter-subunit signaling in gsam
    93% identity, 94% coverage of query (798 bits)

GSA2_ARATH / Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    74% identity, 95% coverage of query (669 bits)

GSA1 / P42799 glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
GSA1_ARATH / P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
P42799 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Arabidopsis thaliana (see paper)
    70% identity, 100% coverage of query (665 bits)

5hdmA / P42799 Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase (see paper)
    73% identity, 94% coverage of query (661 bits)

5hdmB Crystal structure of arabidopsis thaliana glutamate-1-semialdehyde-2, 1-aminomutase
    73% identity, 94% coverage of query (661 bits)

2cfbA / Q8DLK8 Glutamate-1-semialdehyde 2,1-aminomutase from thermosynechococcus elongatus (see paper)
    73% identity, 87% coverage of query (585 bits)

3bs8A / P30949 Crystal structure of glutamate 1-semialdehyde aminotransferase complexed with pyridoxamine-5'-phosphate from bacillus subtilis (see paper)
    59% identity, 93% coverage of query (509 bits)

P30949 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Bacillus subtilis (see paper)
hemL / AAA22515.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus subtilis (see 2 papers)
    59% identity, 93% coverage of query (508 bits)

hemL / CAD48149.1 glutamate-1-semialdehyde 2,1-aminotransferase from Bacillus megaterium (see paper)
    59% identity, 93% coverage of query (503 bits)

hemL / P0CL07 glutamate-1-semialdehyde 2,1-aminomutase subunit (EC 5.4.3.8) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    56% identity, 93% coverage of query (491 bits)

6w80A / B2FT35 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from stenotrophomonas maltophilia k279a in complex with plp
    59% identity, 91% coverage of query (489 bits)

Gsa / b0154 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
hemL / P23893 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Escherichia coli (strain K12) (see 19 papers)
GSA_ECOLI / P23893 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Escherichia coli (strain K12) (see 3 papers)
    56% identity, 93% coverage of query (489 bits)

5i92F / P48247 Crystal structure of glutamate-1-semialdehyde 2,1- aminomutase (gsa) from pseudomonas aeruginosa
    55% identity, 93% coverage of query (473 bits)

3k28A / Q81LD0 Crystal structure of a glutamate-1-semialdehyde aminotransferase from bacillus anthracis with bound pyridoxal 5'phosphate
    58% identity, 94% coverage of query (471 bits)

2e7uA / Q5SJS4 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from thermus thermophilus hb8
    54% identity, 92% coverage of query (458 bits)

Q8NT73 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Corynebacterium glutamicum (see paper)
    49% identity, 92% coverage of query (380 bits)

hemL / BAA21914.1 glutamate 1-semialdehyde 2,1-aminomutase from Propionibacterium freudenreichii (see 2 papers)
    49% identity, 90% coverage of query (374 bits)

GSA_SACS2 / Q980U5 Glutamate-1-semialdehyde 2,1-aminomutase; GSA; Glutamate-1-semialdehyde aminotransferase; GSA-AT; EC 5.4.3.8 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q980U5 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Saccharolobus solfataricus (see paper)
    44% identity, 94% coverage of query (345 bits)

2zsmA / Q9Y9I9 Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from aeropyrum pernix, hexagonal form
    42% identity, 93% coverage of query (332 bits)

D1C218 beta-alanine-pyruvate transaminase (EC 2.6.1.18) from Sphaerobacter thermophilus (see paper)
    35% identity, 87% coverage of query (238 bits)

6k8hB / D1C218 Crystal structure of an omega-transaminase from sphaerobacter thermophilus (see paper)
    35% identity, 87% coverage of query (238 bits)

4zm4B / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
    35% identity, 91% coverage of query (233 bits)

4zm4D / A8R0K5 Complex structure of pctv k276r mutant with pmp and 3-dehydroshkimate (see paper)
    35% identity, 88% coverage of query (219 bits)

BFAT_VARPD / H8WR05 Beta-phenylalanine transaminase; Aromatic beta-amino acid aminotransferase; Beta-phenylalanine aminotransferase; VpAT; EC 2.6.1.- from Variovorax paradoxus (see paper)
H8WR05 tyrosine transaminase (EC 2.6.1.5) from Variovorax paradoxus (see paper)
    36% identity, 91% coverage of query (218 bits)

4ao9A / H8WR05 Biochemical properties and crystal structure of a novel beta-phenylalanine aminotransferase from variovorax paradoxus (see paper)
    36% identity, 91% coverage of query (218 bits)

4aoaA Biochemical properties and crystal structure of a novel beta-phenylalanine aminotransferase from variovorax paradoxus
    36% identity, 91% coverage of query (218 bits)

KAT_CLOAI / B0VH76 3-aminobutyryl-CoA aminotransferase; HemL-like protein; EC 2.6.1.111 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VH76 3-aminobutanoyl-CoA transaminase (EC 2.6.1.111) from Candidatus Cloacimonas acidaminovorans (see paper)
    30% identity, 95% coverage of query (205 bits)

2ykuA / A3EYF7 Structural determinants of the beta-selectivity of a bacterial aminotransferase (see paper)
    34% identity, 85% coverage of query (202 bits)

2ykyA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    34% identity, 85% coverage of query (202 bits)

2ykxA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    34% identity, 85% coverage of query (202 bits)

4ao4A Structural determinants of the beta-selectivity of a bacterial aminotransferase
    34% identity, 85% coverage of query (202 bits)

2ykvA Structural determinants of the beta-selectivity of a bacterial aminotransferase
    34% identity, 85% coverage of query (202 bits)

6ssdA Transaminase with plp bound (see paper)
    33% identity, 91% coverage of query (188 bits)

6ssgA Transaminase with dcs bound
    33% identity, 91% coverage of query (188 bits)

6ssfA Transaminase with lcs bound
    33% identity, 91% coverage of query (188 bits)

6sseA Transaminase with pmp bound
    33% identity, 91% coverage of query (188 bits)

6kfuA / Q9R9J1 A acp-amt fusion protein of hybrid polyketide/non-ribosomal peptide synthetase
    33% identity, 89% coverage of query (181 bits)

MYCA_BACIU / Q9R9J1 Mycosubtilin synthase subunit A; EC 2.3.1.- from Bacillus subtilis (see paper)
    33% identity, 89% coverage of query (180 bits)

6kfrA Amino-transferase (amt) domain - arg complex of hybrid polyketide/non- ribosomal peptide synthetase
    33% identity, 89% coverage of query (180 bits)

bmyA / CAE11250.1 BmyA protein from Bacillus amyloliquefaciens (see paper)
    33% identity, 89% coverage of query (177 bits)

gdnH / K4JEW9 guadinomine polyketide synthase module 4 from Streptomyces sp. K01-0509 (see paper)
    32% identity, 87% coverage of query (173 bits)

mxcL / Q9F631 myxocheline aldehyde aminotransferase from Stigmatella aurantiaca (see 2 papers)
    30% identity, 94% coverage of query (172 bits)

1sf2A / P22256 Structure of e. Coli gamma-aminobutyrate aminotransferase (see paper)
    32% identity, 75% coverage of query (157 bits)

GabT / b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
gabT / P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12) (see 28 papers)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12) (see 6 papers)
    32% identity, 75% coverage of query (157 bits)

1szkA The structure of gamma-aminobutyrate aminotransferase mutant: e211s
    32% identity, 75% coverage of query (157 bits)

1sffA Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
    32% identity, 75% coverage of query (157 bits)

Build an alignment

Build an alignment for Synpcc7942_0645 and 56 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

YC7B_SCHPO / O94492 Uncharacterized aminotransferase C417.11c; EC 2.6.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    29% identity, 91% coverage of query (155 bits)

A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    33% identity, 70% coverage of query (141 bits)

Q9HWU0 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) from Pseudomonas aeruginosa (see paper)
    28% identity, 85% coverage of query (138 bits)

5yktA / Q9HWU0 Crystal structure of a glutamate-1-semialdehyde-aminomutase (k286a) from pseudomonas aeruginosa pao1 in complex with pmp (see paper)
    28% identity, 85% coverage of query (135 bits)

6hbvA / D2D3B2 Structure of plp internal aldimine form of sphingopyxis sp. Mta144 fumi protein
    26% identity, 93% coverage of query (134 bits)

2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
    30% identity, 75% coverage of query (116 bits)

Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
    30% identity, 75% coverage of query (116 bits)

1zobA Crystal structure of dialkylglycine decarboxylases bound with calcium ion
    26% identity, 71% coverage of query (102 bits)

1zc9A The crystal structure of dialkylglycine decarboxylase complex with pyridoxamine 5-phosphate
    26% identity, 71% coverage of query (102 bits)

1m0qA Structure of dialkylglycine decarboxylase complexed with s-1- aminoethanephosphonate
    26% identity, 71% coverage of query (102 bits)

1m0pA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- phenylethanephosphonate
    26% identity, 71% coverage of query (102 bits)

1m0oA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- methylpropanephosphonate
    26% identity, 71% coverage of query (102 bits)

1m0nA Structure of dialkylglycine decarboxylase complexed with 1- aminocyclopentanephosphonate
    26% identity, 71% coverage of query (102 bits)

A0A0A7I435 taurine-2-oxoglutarate transaminase (EC 2.6.1.55) from Bifidobacterium catenulatum subsp. kashiwanohense (see paper)
6jixA / A0A0A7I435 The cyrstal structure of taurine:2-oxoglutarate aminotransferase from bifidobacterium kashiwanohense, in complex with plp and glutamate (see paper)
    27% identity, 73% coverage of query (102 bits)

1dgdA An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase
    26% identity, 71% coverage of query (101 bits)

1d7vA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with nma
    26% identity, 71% coverage of query (101 bits)

1d7uA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with lcs
    26% identity, 71% coverage of query (101 bits)

1d7sA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with dcs
    26% identity, 71% coverage of query (101 bits)

1d7rA / P16932 Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with 5pa (see paper)
    26% identity, 71% coverage of query (101 bits)

5eqcA / S8EY38 Structure of the ornithine aminotransferase from toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of plp at the protein active site
    26% identity, 74% coverage of query (96.7 bits)

5e5iA Structure of the ornithine aminotransferase from toxoplasma gondii in complex with inactivator
    26% identity, 74% coverage of query (96.7 bits)

5e3kA Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    26% identity, 74% coverage of query (96.7 bits)

5dj9A Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with gabaculine
    26% identity, 74% coverage of query (96.7 bits)

5e3kB Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    26% identity, 74% coverage of query (96.7 bits)

3q8nC / A0QQ04 Crystal structure of 4-aminobutyrate transaminase from mycobacterium smegmatis (see paper)
    30% identity, 73% coverage of query (93.6 bits)

5g4jA Phospholyase a1rdf1 from arthrobacter in complex with phosphoethanolamine
    26% identity, 74% coverage of query (93.6 bits)

5g4iA / A1RDF1 Plp-dependent phospholyase a1rdf1 from arthrobacter aurescens tc1 (see paper)
    26% identity, 74% coverage of query (93.6 bits)

6zhkA / Q58696 Crystal structure of adenosylmethionine-8-amino-7-oxononanoate aminotransferase from methanocaldococcus jannaschii dsm 2661
    28% identity, 80% coverage of query (93.2 bits)

1dtyA / P12995 Crystal structure of adenosylmethionine-8-amino-7-oxonanoate aminotransferase with pyridoxal phosphate cofactor.
    28% identity, 77% coverage of query (89.4 bits)

1qj3A Crystal structure of 7,8-diaminopelargonic acid synthase in complex with 7-keto-8-aminopelargonic acid
    29% identity, 77% coverage of query (88.6 bits)

6ed7A Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor mac13772
    28% identity, 77% coverage of query (86.7 bits)

BioA / b0774 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
bioA / P12995 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) from Escherichia coli (strain K12) (see 22 papers)
BIOA_ECOLI / P12995 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; 7,8-diaminononanoate synthase; DANS; Diaminopelargonic acid synthase; EC 2.6.1.62 from Escherichia coli (strain K12) (see 9 papers)
P12995 adenosylmethionine-8-amino-7-oxononanoate transaminase (EC 2.6.1.62) from Escherichia coli (see paper)
    28% identity, 77% coverage of query (86.7 bits)

1mlzA Crystal structure of 7,8-diaminopelargonic acid synthase in complex with the trans-isomer of amiclenomycin.
    28% identity, 77% coverage of query (85.5 bits)

1mlyA Crystal structure of 7,8-diaminopelargonic acid synthase in complex with the cis isomer of amiclenomycin
    28% identity, 77% coverage of query (85.5 bits)

3i5tA / Q3IWE9 Crystal structure of aminotransferase prk07036 from rhodobacter sphaeroides kd131
    25% identity, 74% coverage of query (77.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory