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Searching for up to 100 curated homologs for Synpcc7942_1665 FitnessBrowser__SynE:Synpcc7942_1665 (371 a.a.)

Found high-coverage hits (≥70%) to 53 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

No hits had 30% identity

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Additional hits (identity < 30%)

6a3iA Levoglucosan dehydrogenase, complex with nadh and levoglucosan
    27% identity, 97% coverage of query (120 bits)

6a3jC / F0M433 Levoglucosan dehydrogenase, complex with nadh and l-sorbose (see paper)
    27% identity, 97% coverage of query (119 bits)

Asphe3_10730 / F0M433 levoglucosan dehydrogenase monomer (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (see 2 papers)
LGDH_PSEPM / F0M433 Levoglucosan dehydrogenase; LGDH; 1,6-anhydro-beta-D-glucose dehydrogenase; PpLGDH; EC 1.1.1.425 from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (Arthrobacter phenanthrenivorans) (see paper)
F0M433 levoglucosan dehydrogenase (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (see paper)
    27% identity, 97% coverage of query (115 bits)

K7ZP76 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Paracoccus laeviglucosivorans (see paper)
lgdA / BAM68195.1 scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity from Paracoccus laeviglucosivorans (see 2 papers)
    34% identity, 72% coverage of query (112 bits)

6ktkC / K7ZP76 Crystal structure of scyllo-inositol dehydrogenase r178a mutant, complexed with nadh and l-glucono-1,5-lactone, from paracoccus laeviglucosivorans (see paper)
    34% identity, 71% coverage of query (111 bits)

5yaqB Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with scyllo-inosose
    34% identity, 70% coverage of query (110 bits)

5ya8A Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with myo-inositol
    34% identity, 70% coverage of query (110 bits)

SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) from Sinorhizobium meliloti 1021
    28% identity, 97% coverage of query (105 bits)

Q5KYQ3 inositol 2-dehydrogenase (EC 1.1.1.18) from Geobacillus kaustophilus (see paper)
    23% identity, 97% coverage of query (101 bits)

6jw6A The crystal structure of kand2 in complex with NAD
    32% identity, 71% coverage of query (97.4 bits)

6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
    32% identity, 71% coverage of query (97.1 bits)

6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
    32% identity, 71% coverage of query (97.1 bits)

GFOD2_MOUSE / Q9CYH5 Glucose-fructose oxidoreductase domain-containing protein 2; EC 1.-.-.- from Mus musculus (Mouse) (see paper)
    27% identity, 96% coverage of query (95.5 bits)

HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
    24% identity, 94% coverage of query (94.7 bits)

CCNA_01702 predicted 3-ketohexose reductase from Caulobacter crescentus NA1000
    30% identity, 70% coverage of query (89.7 bits)

iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
    24% identity, 70% coverage of query (86.7 bits)

ntdC / O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (strain 168) (see 4 papers)
NTDC_BACSU / O07564 Glucose-6-phosphate 3-dehydrogenase; EC 1.1.1.361 from Bacillus subtilis (strain 168) (see 3 papers)
O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (see 2 papers)
    24% identity, 94% coverage of query (86.7 bits)

APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
    25% identity, 94% coverage of query (85.1 bits)

YM94_YEAST / Q04869 Uncharacterized protein YMR315W from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    26% identity, 74% coverage of query (78.2 bits)

dfgE / I5AX46 C-glycoside oxidase (EC 1.1.3.50) from [Eubacterium] cellulosolvens 6 (see 2 papers)
    24% identity, 75% coverage of query (77.4 bits)

ligC / Q9KWL3 LigC (EC 1.1.1.312) from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
LIGC_SPHSK / Q9KWL3 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; CHMS dehydrogenase; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase; EC 1.1.1.312 from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
ligC / BAA97119.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 3 papers)
ligC / BAB88744.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 5 papers)
    26% identity, 71% coverage of query (77.4 bits)

proD / Q75T27 α-hydroxy-γ-carboxymuconate ε-semialdehyde dehydrogenase subunit (EC 1.1.1.312) from Pseudomonas straminea (see 2 papers)
proD / BAD04059.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Pseudomonas straminea (see paper)
    26% identity, 71% coverage of query (75.5 bits)

Q93PS4 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (EC 1.1.1.312) from Comamonas testosteroni (see paper)
    26% identity, 71% coverage of query (74.7 bits)

3q2kK / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    25% identity, 72% coverage of query (69.7 bits)

3q2kC / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    25% identity, 72% coverage of query (69.7 bits)

7d5nA Crystal structure of inositol dehydrogenase homolog complexed with nadh and myo-inositol from azotobacter vinelandii
    26% identity, 71% coverage of query (69.7 bits)

IOLU_BACSU / O05265 scyllo-inositol 2-dehydrogenase (NADP(+)) IolU; NADP(+)-dependent scyllo-inositol dehydrogenase 2; NADP(+)-dependent SI dehydrogenase 2; EC 1.1.1.371 from Bacillus subtilis (strain 168) (see 2 papers)
O05265 scyllo-inositol 2-dehydrogenase (NADP+) (EC 1.1.1.371) from Bacillus subtilis (see paper)
    24% identity, 82% coverage of query (69.3 bits)

5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
    21% identity, 94% coverage of query (67.8 bits)

apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
    21% identity, 94% coverage of query (67.8 bits)

5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
    21% identity, 94% coverage of query (67.8 bits)

5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
    21% identity, 94% coverage of query (67.8 bits)

5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
    21% identity, 94% coverage of query (67.8 bits)

3dtyA / Q880Y1 Crystal structure of an oxidoreductase from pseudomonas syringae
    26% identity, 71% coverage of query (67.0 bits)

A0A064C3N0 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Streptococcus pneumoniae (see paper)
    24% identity, 73% coverage of query (67.0 bits)

3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
    21% identity, 95% coverage of query (66.2 bits)

7d5mA / C1DLC3 Crystal structure of inositol dehydrogenase homolog complexed with NAD+ from azotobacter vinelandii
    25% identity, 71% coverage of query (66.2 bits)

Echvi_1844 predicted 3-ketohexose reductase from Echinicola vietnamensis KMM 6221, DSM 17526
    23% identity, 70% coverage of query (66.2 bits)

7d5nB Crystal structure of inositol dehydrogenase homolog complexed with nadh and myo-inositol from azotobacter vinelandii
    25% identity, 71% coverage of query (66.2 bits)

3e18A / Q929L3 Crystal structure of NAD-binding protein from listeria innocua
    24% identity, 71% coverage of query (65.9 bits)

YgjR / b3087 putative oxidoreductase YgjR from Escherichia coli K-12 substr. MG1655
    24% identity, 89% coverage of query (63.9 bits)

5b3uB / P72782 Crystal structure of biliverdin reductase in complex with NADP+ from synechocystis sp. Pcc 6803 (see paper)
    25% identity, 94% coverage of query (60.5 bits)

5b3vA Crystal structure of biliverdin reductase in complex with biliverdin and NADP+ from synechocystis sp. Pcc 6803
    25% identity, 94% coverage of query (60.1 bits)

4mjlD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD and d-chiro-inositol
    26% identity, 71% coverage of query (58.9 bits)

4mioD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
    26% identity, 71% coverage of query (58.9 bits)

4mioA Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
    26% identity, 71% coverage of query (58.9 bits)

4minA / A0A0J9X1Y2 Crystal structure of myo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD
    26% identity, 71% coverage of query (58.9 bits)

3ec7A / Q8ZK57 Crystal structure of putative dehydrogenase from salmonella typhimurium lt2
    21% identity, 96% coverage of query (58.5 bits)

3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
    21% identity, 96% coverage of query (57.4 bits)

3nt5A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor and product inosose
    21% identity, 96% coverage of query (57.0 bits)

3nt4A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor nadh and inositol
    21% identity, 96% coverage of query (57.0 bits)

3nt2B Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
    21% identity, 96% coverage of query (57.0 bits)

3nt2A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
    21% identity, 96% coverage of query (57.0 bits)

4l8vA / P26935 Crystal structure of a12k/d35s mutant myo-inositol dehydrogenase from bacillus subtilis with bound cofactor NADP (see paper)
    21% identity, 96% coverage of query (57.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory