Searching for up to 100 curated homologs for Synpcc7942_1782 FitnessBrowser__SynE:Synpcc7942_1782 (430 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
    40% identity, 93% coverage of query (277 bits)

O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus (see paper)
    37% identity, 82% coverage of query (189 bits)

2zsjA / O66740 Crystal structure of threonine synthase from aquifex aeolicus vf5
    37% identity, 82% coverage of query (189 bits)

6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
    36% identity, 76% coverage of query (178 bits)

thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
    38% identity, 75% coverage of query (178 bits)

6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    36% identity, 76% coverage of query (177 bits)

P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
    37% identity, 81% coverage of query (175 bits)

1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
    37% identity, 81% coverage of query (175 bits)

6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    36% identity, 76% coverage of query (175 bits)

3aeyA Apo form of threonine synthase from thermus thermophilus hb8
    37% identity, 81% coverage of query (175 bits)

1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
    37% identity, 81% coverage of query (175 bits)

A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    37% identity, 80% coverage of query (163 bits)

THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis (see 2 papers)
    36% identity, 78% coverage of query (158 bits)

2d1fA / P9WG59 Structure of mycobacterium tuberculosis threonine synthase (see paper)
    36% identity, 76% coverage of query (157 bits)

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Build an alignment for Synpcc7942_1782 and 14 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    28% identity, 82% coverage of query (128 bits)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    27% identity, 84% coverage of query (127 bits)

THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    28% identity, 83% coverage of query (125 bits)

2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
    27% identity, 82% coverage of query (115 bits)

DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
    26% identity, 90% coverage of query (84.0 bits)

MA_3297 / Q8TKU7 cysteate synthase monomer (EC 2.5.1.76) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
CYAS_METAC / Q8TKU7 Cysteate synthase; CS; Cya synthase; EC 2.5.1.76 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
Q8TKU7 cysteate synthase (EC 2.5.1.76) from Methanosarcina acetivorans (see paper)
    26% identity, 92% coverage of query (83.2 bits)

5ey5B Lbcats
    26% identity, 70% coverage of query (65.1 bits)

trpB / RF|YP_045379.1 tryptophan synthase, beta subunit; EC 4.2.1.20 from Acinetobacter calcoaceticus (see paper)
    22% identity, 70% coverage of query (55.5 bits)

SDSL_MOUSE / Q8R238 Serine dehydratase-like; L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase; TDH; SDH; EC 4.3.1.17; EC 4.3.1.19 from Mus musculus (Mouse) (see paper)
    24% identity, 71% coverage of query (53.5 bits)

TRPB_MYCTU / P9WFX9 Tryptophan synthase beta chain; EC 4.2.1.20 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    26% identity, 71% coverage of query (52.8 bits)

5tciH / P9WFX9 Crystal structure of tryptophan synthase from m. Tuberculosis - brd4592-bound form (see paper)
    26% identity, 71% coverage of query (52.8 bits)

6u6cB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk2-bound form
    26% identity, 71% coverage of query (52.8 bits)

6uapB Crystal structure of tryptophan synthase from m. Tuberculosis - open form with brd6309 bound
    26% identity, 71% coverage of query (52.8 bits)

6usaB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk1-bound form
    26% identity, 71% coverage of query (52.8 bits)

6dweB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and brd0059-bound form
    26% identity, 71% coverage of query (52.8 bits)

5ocwB Structure of mycobacterium tuberculosis tryptophan synthase in space group f222
    26% identity, 71% coverage of query (52.8 bits)

K1QH67 aspartate racemase (EC 5.1.1.13) from Crassostrea gigas (see paper)
    24% identity, 73% coverage of query (51.6 bits)

TRP5 likely tryptophan synthetase alpha chain from Candida albicans (see paper)
    23% identity, 87% coverage of query (50.8 bits)

trpB / CAB55324.2 tryptophan synthase beta subunit from Rhizobium etli (see paper)
    25% identity, 70% coverage of query (50.4 bits)

Q8VBT2 L-serine dehydratase/L-threonine deaminase; SDH; L-serine deaminase; L-threonine dehydratase; TDH; EC 4.3.1.17; EC 4.3.1.19 from Mus musculus (Mouse)
    24% identity, 70% coverage of query (50.1 bits)

B1N2N4 L-serine ammonia-lyase (EC 4.3.1.17) from Entamoeba histolytica (see paper)
    26% identity, 70% coverage of query (49.3 bits)

4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
    24% identity, 73% coverage of query (45.4 bits)

7mfjBBB / T1KF23 7mfjBBB (see paper)
    25% identity, 71% coverage of query (44.3 bits)

2rkbA / Q96GA7 Serine dehydratase like-1 from human cancer cells (see paper)
    23% identity, 71% coverage of query (43.9 bits)

SDSL / Q96GA7 Serine dehydratase-like (EC 4.3.1.19; EC 4.3.1.17) from Homo sapiens (see paper)
SDSL_HUMAN / Q96GA7 Serine dehydratase-like; L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase; TDH; Serine dehydratase 2; SDH 2; EC 4.3.1.19; EC 4.3.1.17 from Homo sapiens (Human) (see paper)
Q96GA7 L-serine ammonia-lyase (EC 4.3.1.17) from Homo sapiens (see paper)
    23% identity, 71% coverage of query (43.9 bits)

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