Searching for up to 100 curated homologs for Synpcc7942_1973 FitnessBrowser__SynE:Synpcc7942_1973 (389 a.a.)
Found high-coverage hits (≥70%) to 76 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CUGP_SYNY3 / P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P74285 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Synechocystis sp. (see paper)
79% identity, 94% coverage of query (626 bits)
GMPPB_DANRE / Q6DBU5 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q6DBU5 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Danio rerio (see paper)
33% identity, 87% coverage of query (150 bits)
7whsA / E9BG32 Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gtp (see paper)
30% identity, 97% coverage of query (140 bits)
GMPPB_PIG / P0C5I2 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase 37-kDa subunit; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Sus scrofa (Pig) (see 2 papers)
31% identity, 82% coverage of query (138 bits)
Build an alignment for Synpcc7942_1973 and 4 homologs with ≥ 30% identity
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A4I048 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Leishmania infantum (see paper)
29% identity, 97% coverage of query (137 bits)
GMPPB_HUMAN / Q9Y5P6 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Homo sapiens (Human) (see 4 papers)
Q9Y5P6 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Homo sapiens (see paper)
7d72K / Q9Y5P6 Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
31% identity, 82% coverage of query (137 bits)
7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i)
31% identity, 82% coverage of query (137 bits)
7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose
31% identity, 82% coverage of query (137 bits)
Q4CMK4 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Trypanosoma cruzi (see paper)
31% identity, 87% coverage of query (132 bits)
GMPP_MYCTU / L7N6A5 Mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; GMP; GMPP; EC 2.7.7.13 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
29% identity, 87% coverage of query (132 bits)
7whtA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gdp-mannose
29% identity, 97% coverage of query (132 bits)
Q54K39 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Solanum lycopersicum (see paper)
31% identity, 84% coverage of query (129 bits)
Q941T9 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Oryza sativa Japonica Group (see paper)
29% identity, 87% coverage of query (129 bits)
A0EJL9 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13); mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) from Malpighia glabra (see 2 papers)
30% identity, 85% coverage of query (128 bits)
Q6Z9A3 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Oryza sativa Japonica Group (see paper)
29% identity, 87% coverage of query (127 bits)
Q84JH5 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Oryza sativa Japonica Group (see paper)
30% identity, 87% coverage of query (127 bits)
MPG1_CANAL / O93827 Mannose-1-phosphate guanyltransferase; ATP-mannose-1-phosphate guanylyltransferase; CASRB1; GDP-mannose pyrophosphorylase; EC 2.7.7.13 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
O93827 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Candida albicans (see paper)
SRB1 / GB|BAA34807.1 mannose-1-phosphate guanyltransferase; EC 2.7.7.13 from Candida albicans (see 5 papers)
30% identity, 87% coverage of query (126 bits)
MPG1_KLULA / Q70SJ2 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) (see paper)
31% identity, 87% coverage of query (125 bits)
MPG1_YEAST / P41940 Mannose-1-phosphate guanyltransferase; ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase; EC 2.7.7.13 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P41940 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Saccharomyces cerevisiae (see 3 papers)
MPG1 / GI|1431053 mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Saccharomyces cerevisiae (see 5 papers)
29% identity, 88% coverage of query (124 bits)
7x8kB / O22287 Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
30% identity, 87% coverage of query (123 bits)
CYT1 / O22287 GDP-D-mannose pyrophosphorylase (EC 2.7.7.13) from Arabidopsis thaliana (see paper)
GMPP1_ARATH / O22287 Mannose-1-phosphate guanylyltransferase 1; GDP-mannose pyrophosphorylase 1; Protein CYTOKINESIS DEFECTIVE 1; Protein EMBRYO DEFECTIVE 101; Protein HYPERSENSITIVE TO AMMONIUM ION 1; Protein SENSITIVE TO OZONE 1; Protein VITAMIN C DEFECTIVE 1; EC 2.7.7.13 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
O22287 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Arabidopsis thaliana (see 2 papers)
30% identity, 87% coverage of query (123 bits)
agl11 / D4GU70 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL11_HALVD / D4GU70 Low-salt glycan biosynthesis nucleotidyltransferase Agl11; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
30% identity, 87% coverage of query (123 bits)
Q6J1L7 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13); mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) from Solanum lycopersicum (see paper)
28% identity, 87% coverage of query (122 bits)
7x8kA Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound)
30% identity, 87% coverage of query (122 bits)
B9WNA1 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Trypanosoma brucei (see paper)
29% identity, 87% coverage of query (121 bits)
MPG1_SCHPO / O74484 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
mpg1 / RF|NP_588405.1 mannose-1-phosphate guanyltransferase Mpg1; EC 2.7.7.13 from Schizosaccharomyces pombe (see 2 papers)
30% identity, 87% coverage of query (120 bits)
MPG1_PICAN / Q9P8N0 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Pichia angusta (Yeast) (Hansenula polymorpha) (see paper)
28% identity, 84% coverage of query (120 bits)
Q9M2S0 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Arabidopsis thaliana (see paper)
30% identity, 87% coverage of query (120 bits)
Q4U3E8 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Aspergillus fumigatus (see paper)
29% identity, 84% coverage of query (119 bits)
MPG11_CANGA / Q9Y725 Mannose-1-phosphate guanyltransferase 1; ATP-mannose-1-phosphate guanylyltransferase 1; GDP-mannose pyrophosphorylase 1; EC 2.7.7.13 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
Q9Y725 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from [Candida] glabrata (see paper)
29% identity, 84% coverage of query (119 bits)
MPG1_HYPJE / O74624 Mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Hypocrea jecorina (Trichoderma reesei) (see paper)
O74624 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Trichoderma reesei (see 2 papers)
29% identity, 100% coverage of query (116 bits)
mtmD / Q194R4 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces argillaceus (see paper)
mtmD / CAK50774.1 dTDP-glucose synthase from Streptomyces argillaceus (see 21 papers)
28% identity, 86% coverage of query (112 bits)
dnmL / C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius subsp. caesius ATCC 27952 (see 2 papers)
C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius (see paper)
30% identity, 87% coverage of query (109 bits)
oleS / Q9RR29 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces antibioticus (see paper)
OLES_STRAT / Q9RR29 Glucose-1-phosphate thymidylyltransferase; EC 2.7.7.24 from Streptomyces antibioticus (see paper)
30% identity, 87% coverage of query (108 bits)
Q2HR55 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces sp. (see paper)
29% identity, 88% coverage of query (107 bits)
Q400H3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Thermus caldophilus (see paper)
30% identity, 87% coverage of query (106 bits)
ravd / D1H0J0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces ravidus (see 2 papers)
30% identity, 87% coverage of query (101 bits)
Q8H1Q7 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Arabidopsis thaliana (see paper)
28% identity, 82% coverage of query (101 bits)
GLMU_METJA / Q58501 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
27% identity, 85% coverage of query (100 bits)
M9TIK1 glucose-1-phosphate adenylyltransferase (subunit 2/2) (EC 2.7.7.27) from Streptococcus mutans (see paper)
25% identity, 87% coverage of query (100 bits)
glgC / BAA19589.1 subunit of ADP-glucose pyrophosphorylase from Geobacillus stearothermophilus (see 2 papers)
28% identity, 82% coverage of query (95.5 bits)
YBB2_SCHPO / O60064 Probable mannose-1-phosphate guanyltransferase; GDP-mannose pyrophosphorylase; GTP-mannose-1-phosphate guanylyltransferase; EC 2.7.7.13 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 87% coverage of query (88.6 bits)
5z09A St0452(y97n)-utp binding form
26% identity, 87% coverage of query (87.4 bits)
ST0452 / Q975F9 multifunctional glucose-1-phosphate thymidylyltransferase/hexosamine-1-phosphate N-acetyltransferase/UDP-N-acetylhexosamine diphosphorylase (EC 2.7.7.24; EC 2.7.7.23; EC 2.7.7.83; EC 2.3.1.157; EC 2.3.1.276) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see 2 papers)
S1PNA_SULTO / Q975F9 Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase; EC 2.7.7.24; EC 2.7.7.9; EC 2.7.7.83; EC 2.7.7.23; EC 2.3.1.276; EC 2.3.1.157 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 5 papers)
Q975F9 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); galactosamine-1-phosphate N-acetyltransferase (EC 2.3.1.276); UDP-N-acetylglucosamine diphosphorylase (EC 2.7.7.23); glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24); aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37); UDP-N-acetylgalactosamine diphosphorylase (EC 2.7.7.83); UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sulfurisphaera tokodaii (see 7 papers)
2ggqA / Q975F9 Complex of hypothetical glucose-1-phosphate thymidylyltransferase from sulfolobus tokodaii
26% identity, 87% coverage of query (87.0 bits)
Q0S3Y4 glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) from Rhodococcus jostii (see paper)
24% identity, 90% coverage of query (85.1 bits)
glgC / P9WN43 glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GLGC_MYCTU / P9WN43 Glucose-1-phosphate adenylyltransferase; ADP-glucose pyrophosphorylase; ADPGlc PPase; ADP-glucose synthase; EC 2.7.7.27 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
24% identity, 84% coverage of query (82.4 bits)
7d73B Cryo-em structure of gmppa/gmppb complex bound to gtp (state i)
26% identity, 87% coverage of query (79.0 bits)
7d72A / Q96IJ6 Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
25% identity, 87% coverage of query (77.4 bits)
5w5rA / P39669 Agrobacterium tumefaciens adp-glucose pyrophosphorylase p96a mutant bound to activator pyruvate (see paper)
24% identity, 90% coverage of query (72.0 bits)
5w5tA Agrobacterium tumefaciens adp-glucose pyrophosphorylase bound to activator ethyl pyruvate
23% identity, 90% coverage of query (70.9 bits)
EI2BE_YEAST / P32501 Translation initiation factor eIF2B subunit epsilon; GCD complex subunit GCD6; Guanine nucleotide exchange factor subunit GCD6; eIF2B GDP-GTP exchange factor subunit epsilon from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
P32501 protein-synthesizing GTPase (EC 3.6.5.3) from Saccharomyces cerevisiae (see paper)
22% identity, 87% coverage of query (68.6 bits)
3brkX Crystal structure of adp-glucose pyrophosphorylase from agrobacterium tumefaciens
22% identity, 90% coverage of query (65.9 bits)
6jlzI / P56287 P-eif2a - eif2b complex (see paper)
20% identity, 89% coverage of query (61.6 bits)
EI2BE_SCHPO / P56287 Translation initiation factor eIF2B subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 4 papers)
20% identity, 89% coverage of query (61.6 bits)
GLGL2_ORYSJ / Q7G065 Glucose-1-phosphate adenylyltransferase large subunit 2, cytosolic; OsAGPL2; OsAPL2; ADP-glucose pyrophosphorylase AGPL2; ADP-glucose synthase AGPL2; Protein FLOURY ENDOSPERM 6; Protein GRAIN INCOMPLETE FILLING 2; Protein SHRUNKEN 1; EC 2.7.7.27 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
Q7G065 glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) from Oryza sativa (see paper)
23% identity, 87% coverage of query (60.5 bits)
YieA / b3730 fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase (EC 2.7.7.23; EC 2.3.1.157) from Escherichia coli K-12 substr. MG1655 (see 15 papers)
glmU / P0ACC7 fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase (EC 2.7.7.23; EC 2.3.1.157) from Escherichia coli (strain K12) (see 13 papers)
GLMU_ECOLI / P0ACC7 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Escherichia coli (strain K12) (see 8 papers)
P0ACC7 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); UDP-N-acetylglucosamine diphosphorylase (EC 2.7.7.23) from Escherichia coli (see 8 papers)
glmU / GB|AAC76753.1 bifunctional protein glmU; EC 2.3.1.157; EC 2.7.7.23 from Escherichia coli (see 10 papers)
24% identity, 88% coverage of query (58.5 bits)
2oi7A E. Coli glmu- complex with udp-glcnac, desulpho-coa and glcnac-1-po4
24% identity, 88% coverage of query (58.5 bits)
2oi5A E. Coli glmu- complex with udp-glcnac and acetyl-coa
24% identity, 88% coverage of query (58.5 bits)
1hv9B Structure of e. Coli glmu: analysis of pyrophosphorylase and acetyltransferase active sites
24% identity, 88% coverage of query (58.5 bits)
2oi6B / P0ACC7 E. Coli glmu- complex with udp-glcnac, coa and glcn-1-po4 (see paper)
24% identity, 88% coverage of query (58.2 bits)
4kqlA Hin glmu bound to wg578
24% identity, 88% coverage of query (53.9 bits)
4kpzA Hin glmu bound to a small molecule fragment
24% identity, 88% coverage of query (53.9 bits)
4kpxA Hin glmu bound to wg766
24% identity, 88% coverage of query (53.9 bits)
4knxA Hin glmu bound to wg176
24% identity, 88% coverage of query (53.9 bits)
4knrA Hin glmu bound to wg188
24% identity, 88% coverage of query (53.9 bits)
4e1kA / P43889 Glmu in complex with a quinazoline compound (see paper)
24% identity, 88% coverage of query (53.9 bits)
2w0wA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 2
24% identity, 88% coverage of query (53.9 bits)
2w0vA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 1
24% identity, 88% coverage of query (53.9 bits)
2vd4A Structure of small-molecule inhibitor of glmu from haemophilus influenzae reveals an allosteric binding site
24% identity, 88% coverage of query (53.9 bits)
2v0lA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
24% identity, 88% coverage of query (53.9 bits)
2v0kA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1- phosphate uridyltransferase (glmu)
24% identity, 88% coverage of query (53.9 bits)
2v0iA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
24% identity, 88% coverage of query (53.9 bits)
2v0jA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
24% identity, 88% coverage of query (53.9 bits)
GLMU_HAEIN / P43889 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
P43889 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) from Haemophilus influenzae (see paper)
24% identity, 88% coverage of query (53.9 bits)
Q8Z9S7 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Yersinia pestis
24% identity, 88% coverage of query (50.4 bits)
4fceA / Q8Z9S7 Crystal structure of yersinia pestis glmu in complex with alpha-d- glucosamine 1-phosphate (gp1)
24% identity, 88% coverage of query (47.8 bits)
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