Searching for up to 100 curated homologs for Synpcc7942_2612 FitnessBrowser__SynE:Synpcc7942_2612 (366 a.a.)
Found high-coverage hits (≥70%) to 88 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
2zsjA / O66740 Crystal structure of threonine synthase from aquifex aeolicus vf5
60% identity, 95% coverage of query (411 bits)
O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus (see paper)
60% identity, 95% coverage of query (411 bits)
6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
61% identity, 90% coverage of query (410 bits)
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
61% identity, 90% coverage of query (409 bits)
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
60% identity, 89% coverage of query (394 bits)
P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
59% identity, 88% coverage of query (386 bits)
3aeyA Apo form of threonine synthase from thermus thermophilus hb8
59% identity, 88% coverage of query (386 bits)
1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
59% identity, 88% coverage of query (386 bits)
1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
59% identity, 88% coverage of query (386 bits)
thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
58% identity, 89% coverage of query (379 bits)
THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis (see 2 papers)
58% identity, 91% coverage of query (374 bits)
A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
58% identity, 89% coverage of query (374 bits)
2d1fA / P9WG59 Structure of mycobacterium tuberculosis threonine synthase (see paper)
59% identity, 89% coverage of query (373 bits)
THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
51% identity, 88% coverage of query (303 bits)
THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
34% identity, 91% coverage of query (193 bits)
THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
34% identity, 89% coverage of query (190 bits)
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
34% identity, 89% coverage of query (190 bits)
2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
33% identity, 89% coverage of query (177 bits)
DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
34% identity, 85% coverage of query (143 bits)
Build an alignment for Synpcc7942_2612 and 19 homologs with ≥ 30% identity
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CysM / b2421 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
cysM / P16703 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1) from Escherichia coli (strain K12) (see 15 papers)
CYSM_ECOLI / P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
28% identity, 85% coverage of query (78.6 bits)
2bhtA / P16703 Crystal structure of o-acetylserine sulfhydrylase b (see paper)
28% identity, 82% coverage of query (75.1 bits)
CA265_RS15860 threonine deaminase (EC 4.3.1.19) from Pedobacter sp. GW460-11-11-14-LB5
24% identity, 74% coverage of query (74.3 bits)
A0QX60 threonine ammonia-lyase (EC 4.3.1.19) from Mycolicibacterium smegmatis (see paper)
29% identity, 80% coverage of query (74.3 bits)
P29848 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) (EC 2.5.1.144); cysteine synthase (EC 2.5.1.47) from Salmonella enterica subsp. enterica serovar Typhimurium (see 9 papers)
27% identity, 85% coverage of query (73.2 bits)
4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
26% identity, 79% coverage of query (71.2 bits)
L0N5C4 threo-3-hydroxy-L-aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. N99 (see paper)
30% identity, 80% coverage of query (70.5 bits)
B1N2N4 L-serine ammonia-lyase (EC 4.3.1.17) from Entamoeba histolytica (see paper)
25% identity, 78% coverage of query (70.1 bits)
Q54HH2 D-Serine ammonia-lyase (EC 4.3.1.18) from Dictyostelium discoideum (see paper)
27% identity, 74% coverage of query (68.9 bits)
CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
26% identity, 79% coverage of query (68.6 bits)
8s5hA / P35520 Full-length human cystathionine beta-synthase with c-terminal 6xhis- tag, basal state, helical reconstruction (see paper)
26% identity, 79% coverage of query (68.6 bits)
thadh / A4F2N8 L-threo-3-hydroxy aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. (see 2 papers)
LTHAD_PSESP / A4F2N8 L-threo-3-hydroxyaspartate ammonia-lyase; L-threo-3-hydroxyaspartate dehydratase; L-THA DH; EC 4.3.1.16 from Pseudomonas sp. (see 2 papers)
A4F2N8 threo-3-hydroxy-L-aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. T62 (see paper)
30% identity, 79% coverage of query (68.2 bits)
7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
26% identity, 79% coverage of query (68.2 bits)
1jbqA Structure of human cystathionine beta-synthase: a unique pyridoxal 5'- phosphate dependent hemeprotein
25% identity, 79% coverage of query (67.4 bits)
sr / Q2PGG3 serine racemase/D-serine ammonia-lyase (EC 5.1.1.10) from Arabidopsis thaliana (see paper)
SRR_ARATH / Q2PGG3 Serine racemase; AtSR; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 4.3.1.17; EC 4.3.1.18; EC 5.1.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q2PGG3 serine racemase (EC 5.1.1.18) from Arabidopsis thaliana (see paper)
25% identity, 84% coverage of query (66.6 bits)
ortB / C1FW07 AKP thiolase β subunit (EC 2.3.1.263) from Unknown prokaryotic organism (see 2 papers)
ORTB_UNKP / C1FW07 2-amino-4-ketopentanoate thiolase beta subunit; AKP thiolase; AKPT; EC 2.3.1.263 from Unknown prokaryotic organism (see paper)
C1FW07 2-amino-4-oxopentanoate thiolase (subunit 2/2) (EC 2.3.1.263) from Acetoanaerobium sticklandii (see paper)
26% identity, 83% coverage of query (66.6 bits)
Q8VBT2 L-serine dehydratase/L-threonine deaminase; SDH; L-serine deaminase; L-threonine dehydratase; TDH; EC 4.3.1.17; EC 4.3.1.19 from Mus musculus (Mouse)
25% identity, 77% coverage of query (66.6 bits)
2zpuA / O59791 Crystal structure of modified serine racemase from s.Pombe. (see paper)
25% identity, 84% coverage of query (65.1 bits)
SRR_SCHPO / O59791 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 4.3.1.17; EC 4.3.1.18; EC 5.1.1.18 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
O59791 serine racemase (EC 5.1.1.18) from Schizosaccharomyces pombe (see 2 papers)
25% identity, 84% coverage of query (65.1 bits)
TSAL_GEOSL / Q74FW6 L-threonine ammonia-lyase; L-serine ammonia-lyase; Threonine/serine ammonia-lyase; EC 4.3.1.19; EC 4.3.1.17 from Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) (see paper)
Q74FW6 threonine ammonia-lyase (EC 4.3.1.19) from Geobacter sulfurreducens (see paper)
29% identity, 75% coverage of query (65.1 bits)
2zr8A Crystal structure of modified serine racemase complexed with serine
25% identity, 84% coverage of query (65.1 bits)
1wtcA Crystal structure of s.Pombe serine racemase complex with amppcp
25% identity, 84% coverage of query (65.1 bits)
1v71A Crystal structure of s.Pombe serine racemase
25% identity, 84% coverage of query (65.1 bits)
Cbs / P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus (see 2 papers)
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat) (see 3 papers)
25% identity, 81% coverage of query (64.7 bits)
CS1 / A2EI82 O-phosphoserine sulfhydrylase monomer (EC 2.5.1.47; EC 2.5.1.65) from Trichomonas vaginalis (strain ATCC PRA-98 / G3) (see paper)
26% identity, 82% coverage of query (62.8 bits)
Q04513 threonine ammonia-lyase (EC 4.3.1.19) from Corynebacterium glutamicum (see paper)
26% identity, 79% coverage of query (62.0 bits)
A2GMG5 cysteine synthase (EC 2.5.1.47) from Trichomonas vaginalis (see paper)
25% identity, 78% coverage of query (60.8 bits)
Q93968 serine racemase (EC 5.1.1.18) from Caenorhabditis elegans (see paper)
23% identity, 75% coverage of query (59.3 bits)
cdl / Q8L0X3 L-cysteine desulfhydrase (EC 4.4.1.1) from Fusobacterium nucleatum (see paper)
Q8L0X3 L-cysteine desulfidase (EC 4.4.1.28) from Fusobacterium nucleatum (see paper)
26% identity, 82% coverage of query (58.5 bits)
A0A0F6AQU1 cysteine synthase (EC 2.5.1.47) from Brucella abortus (see paper)
26% identity, 80% coverage of query (57.8 bits)
A0A0X1KHE6 L-serine ammonia-lyase (EC 4.3.1.17) from Rhizomucor miehei (see paper)
25% identity, 73% coverage of query (57.4 bits)
5c3uA / A0A0X1KHE6 Crystal structure of a fungal l-serine ammonia-lyase from rhizomucor miehei (see paper)
25% identity, 73% coverage of query (57.4 bits)
TSB2 / AAA33491.1 tryptophan synthase beta-subunit from Zea mays (see paper)
24% identity, 79% coverage of query (57.4 bits)
ILV / CAA10977.1 threonine deaminase from Blastobotrys adeninivorans (see paper)
24% identity, 81% coverage of query (57.0 bits)
6u6cB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk2-bound form
24% identity, 82% coverage of query (56.6 bits)
5ocwB Structure of mycobacterium tuberculosis tryptophan synthase in space group f222
24% identity, 82% coverage of query (56.6 bits)
TRPB_MYCTU / P9WFX9 Tryptophan synthase beta chain; EC 4.2.1.20 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
24% identity, 82% coverage of query (56.2 bits)
5tciH / P9WFX9 Crystal structure of tryptophan synthase from m. Tuberculosis - brd4592-bound form (see paper)
24% identity, 82% coverage of query (56.2 bits)
SDSL / Q96GA7 Serine dehydratase-like (EC 4.3.1.19; EC 4.3.1.17) from Homo sapiens (see paper)
SDSL_HUMAN / Q96GA7 Serine dehydratase-like; L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase; TDH; Serine dehydratase 2; SDH 2; EC 4.3.1.19; EC 4.3.1.17 from Homo sapiens (Human) (see paper)
Q96GA7 L-serine ammonia-lyase (EC 4.3.1.17) from Homo sapiens (see paper)
28% identity, 75% coverage of query (56.2 bits)
6uapB Crystal structure of tryptophan synthase from m. Tuberculosis - open form with brd6309 bound
24% identity, 82% coverage of query (56.2 bits)
6usaB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and gsk1-bound form
24% identity, 82% coverage of query (56.2 bits)
6dweB Crystal structure of tryptophan synthase from m. Tuberculosis - aminoacrylate- and brd0059-bound form
24% identity, 82% coverage of query (56.2 bits)
MA_3297 / Q8TKU7 cysteate synthase monomer (EC 2.5.1.76) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
CYAS_METAC / Q8TKU7 Cysteate synthase; CS; Cya synthase; EC 2.5.1.76 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
Q8TKU7 cysteate synthase (EC 2.5.1.76) from Methanosarcina acetivorans (see paper)
24% identity, 93% coverage of query (55.8 bits)
2rkbA / Q96GA7 Serine dehydratase like-1 from human cancer cells (see paper)
28% identity, 75% coverage of query (55.8 bits)
5xemA / Q8RE94 Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-lanthionine-plp schiff base
26% identity, 80% coverage of query (55.5 bits)
cysK / P56067 cystathionine β-synthase (O-acetyl-L-serine) monomer (EC 4.2.1.22; EC 2.5.1.134; EC 2.5.1.47) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
6ahiB / P56067 Crystal structure of o-acetylserine dependent cystathionine beta- synthase from helicobacter pylori. (see paper)
24% identity, 80% coverage of query (55.5 bits)
5xenA Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-serine-plp schiff base
26% identity, 80% coverage of query (55.5 bits)
ilvA / AAA96639.1 threonine dehydratase from Bacillus subtilis (see 3 papers)
23% identity, 74% coverage of query (55.1 bits)
ILV1 putative uncharacterized protein ILV1 from Candida albicans (see paper)
23% identity, 88% coverage of query (53.9 bits)
6zspAAA serine racemase bound to atp and malonate.
25% identity, 82% coverage of query (53.9 bits)
7nbgAAA structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen
25% identity, 82% coverage of query (53.5 bits)
7nbfAAA structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen
25% identity, 82% coverage of query (53.5 bits)
7nbdAAA structure of human serine racemase in complex with DSiP fragment Z235449082, XChem fragment screen
25% identity, 82% coverage of query (53.5 bits)
7nbcCCC structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen
25% identity, 82% coverage of query (53.5 bits)
7nbcAAA / Q9GZT4 structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen (see paper)
25% identity, 82% coverage of query (53.5 bits)
7nbhAAA structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen
25% identity, 81% coverage of query (53.1 bits)
3l6bA X-ray crystal structure of human serine racemase in complex with malonate a potent inhibitor
25% identity, 82% coverage of query (52.0 bits)
SRR_ORYSJ / Q7XSN8 Serine racemase; D-serine dehydratase; D-serine ammonia-lyase; L-serine dehydratase; L-serine ammonia-lyase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q7XSN8 serine racemase (EC 5.1.1.18) from Oryza sativa (see paper)
24% identity, 74% coverage of query (51.2 bits)
7nbgDDD structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen
25% identity, 79% coverage of query (51.2 bits)
P09367 L-serine dehydratase/L-threonine deaminase; SDH; L-serine deaminase; L-threonine dehydratase; TDH; EC 4.3.1.17; EC 4.3.1.19 from Rattus norvegicus (Rat)
23% identity, 77% coverage of query (49.7 bits)
5d86A Staphyloferrin b precursor biosynthetic enzyme sbna y152f variant
24% identity, 82% coverage of query (47.4 bits)
SRR_MOUSE / Q9QZX7 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Mus musculus (Mouse) (see 5 papers)
24% identity, 80% coverage of query (47.4 bits)
5d85A Staphyloferrin b precursor biosynthetic enzyme sbna bound to aminoacrylate intermediate
24% identity, 82% coverage of query (47.0 bits)
5d84A / A6QDA0 Staphyloferrin b precursor biosynthetic enzyme sbna bound to plp (see paper)
24% identity, 82% coverage of query (46.6 bits)
3x43A Crystal structure of o-ureido-l-serine synthase
25% identity, 80% coverage of query (46.6 bits)
sbnA / Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
SBNA_STAAE / A6QDA0 N-(2-amino-2-carboxyethyl)-L-glutamate synthase; ACEGA synthase; Staphyloferrin B biosynthesis protein SbnA; EC 2.5.1.140 from Staphylococcus aureus (strain Newman) (see 3 papers)
SBNA_STAA8 / Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase; ACEGA synthase; Staphyloferrin B biosynthesis protein SbnA; EC 2.5.1.140 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
A6QDA0 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (see 2 papers)
Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (see paper)
24% identity, 82% coverage of query (46.6 bits)
dcsD / D2Z027 O-ureido-L-serine synthase (EC 2.5.1.47; EC 2.6.99.3) from Streptomyces lavendulae (see 2 papers)
DCSD_STRLA / D2Z027 O-ureido-L-serine synthase; Cysteine synthase homolog DscD; O-acetylserine sulfhydrylase; EC 2.6.99.3; EC 2.5.1.47 from Streptomyces lavendulae (see 3 papers)
D2Z027 cysteine synthase (EC 2.5.1.47); O-ureido-L-serine synthase (EC 2.6.99.3) from Streptomyces lavendulae (see 4 papers)
25% identity, 80% coverage of query (46.2 bits)
2rhgB / P0A2K1 Tryptophan synthase complexed with igp, ph 7.0, internal aldimine
23% identity, 77% coverage of query (46.2 bits)
3x44A / D2Z027 Crystal structure of o-ureido-l-serine-bound k43a mutant of o-ureido- l-serine synthase (see paper)
25% identity, 80% coverage of query (43.9 bits)
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