Searching for up to 100 curated homologs for WP_002719715.1 NCBI__GCF_000015985.1:WP_002719715.1 (312 a.a.)
Found high-coverage hits (≥70%) to 82 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
2ux8G / Q5FYV5 Crystal structure of sphingomonas elodea atcc 31461 glucose-1- phosphate uridylyltransferase in complex with glucose-1-phosphate. (see paper)
56% identity, 89% coverage of query (318 bits)
A0A0W1QGK2 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sphingomonas sp. WG (see paper)
54% identity, 90% coverage of query (314 bits)
epsT / BAC55148.1 UDP-glucose pyrophosphorylase EpsT from Methylobacillus sp. 12S (see paper)
48% identity, 96% coverage of query (285 bits)
gtaB / Q05852 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Bacillus subtilis (strain 168) (see 3 papers)
GTAB_BACSU / Q05852 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; UGPase; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Bacillus subtilis (strain 168) (see 6 papers)
49% identity, 92% coverage of query (285 bits)
5i1fA / A4JT02 Crystal structure of utp-glucose-1-phosphate uridylyltransferase from burkholderia vietnamiensis in complex with uridine-5'-diphosphate- glucose
51% identity, 92% coverage of query (283 bits)
gtaB / Q2G1T6 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
GTAB_STAA8 / Q2G1T6 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
47% identity, 92% coverage of query (278 bits)
A0A0H2X8N4 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas campestris pv. campestris (see paper)
51% identity, 88% coverage of query (275 bits)
Q8PK83 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas citri (see paper)
50% identity, 92% coverage of query (275 bits)
5ve7A / B1YNX3 Crystal structure of utp-glucose-1-phosphate uridylyltransferase from burkholderia ambifaria in complex with utp
49% identity, 91% coverage of query (273 bits)
AAV49509.1 UDP-glucose pyrophosphorylase from Acidithiobacillus ferrooxidans (see paper)
47% identity, 93% coverage of query (266 bits)
CAA80348.1 ExoN from Sinorhizobium meliloti (see paper)
48% identity, 89% coverage of query (261 bits)
2ux8A / Q5FYV5 Crystal structure of sphingomonas elodea atcc 31461 glucose-1- phosphate uridylyltransferase in complex with glucose-1-phosphate. (see paper)
48% identity, 89% coverage of query (249 bits)
6k8dA / X2KZJ9 Udp-glucose pyrophosphorylase with upg from acinetobacter baumanii
46% identity, 91% coverage of query (243 bits)
YNGB_BACSU / O31822 UTP--glucose-1-phosphate uridylyltransferase YngB; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; UGPase; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Bacillus subtilis (strain 168) (see paper)
43% identity, 93% coverage of query (243 bits)
6knlA Uridine and triphosphate-bound ugpase from acinetobacter baumannii
46% identity, 91% coverage of query (243 bits)
8f73E / Q9I291 Crystal structure of pseudomonas aeruginosa udp-glucose phosphorylase in complex with udp-glucose (see paper)
46% identity, 85% coverage of query (239 bits)
6ikzB Udp-glucose pyrophosphorylase from acinetobacter baumanii
45% identity, 91% coverage of query (233 bits)
O25363 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Helicobacter pylori (see paper)
43% identity, 87% coverage of query (226 bits)
Q54800 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus pneumoniae (see paper)
cap3C / CAA87405.1 glucosephosphate uridylyltransferase from Streptococcus pneumoniae (see 2 papers)
42% identity, 93% coverage of query (222 bits)
Q8GQP8 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus equi (see paper)
hasC / AAN65250.1 UDP-glucose pyrophosphorylase from Streptococcus equi subsp. zooepidemicus (see paper)
42% identity, 93% coverage of query (221 bits)
galU / CAA06172.1 UTP-glucose-1-phosphate uridylyltransferase from Streptococcus pneumoniae (see paper)
41% identity, 94% coverage of query (220 bits)
3jukA / O25363 The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose (see paper)
44% identity, 87% coverage of query (219 bits)
GalU / b1236 UTP—glucose-1-phosphate uridylyltransferase (EC 2.7.7.64; EC 2.7.7.9) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
galU / P0AEP3 UTP—glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Escherichia coli (strain K12) (see 30 papers)
GALU_ECOLI / P0AEP3 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-Glc PPase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Escherichia coli (strain K12) (see 2 papers)
GALU_SHIFL / P0AEP6 UTP--glucose-1-phosphate uridylyltransferase; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Shigella flexneri (see paper)
galU UTP--glucose-1-phosphate uridylyltransferase; EC 2.7.7.9 from Escherichia coli K12 (see 7 papers)
galU / AAA20118.1 glucosephosphate uridylyltransferase from Escherichia coli (see 3 papers)
galU / AAD15244.1 UDP-glucose pyrophosphorylase from Shigella flexneri (see paper)
44% identity, 92% coverage of query (219 bits)
3jukD The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose
44% identity, 87% coverage of query (219 bits)
A0A0H2ZMV4 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus pneumoniae (see paper)
40% identity, 94% coverage of query (217 bits)
8b6dA / A0A2W4LV58 Crystal structure of udp-glucose pyrophosphorylase from thermocrispum agreste dsm 44070 in complex with udp
44% identity, 90% coverage of query (201 bits)
YefG / b2042 UTP:glucose-1-phosphate uridylyltransferase, low activity from Escherichia coli K-12 substr. MG1655 (see 7 papers)
42% identity, 86% coverage of query (193 bits)
galF / AAC63611.1 GalF from Escherichia coli (see 6 papers)
41% identity, 91% coverage of query (190 bits)
8b68A Crystal structure of udp-glucose pyrophosphorylase from thermocrispum agreste dsm 44070 in complex with udp-glucose
42% identity, 90% coverage of query (185 bits)
O05576 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Mycobacterium tuberculosis (see paper)
42% identity, 91% coverage of query (179 bits)
2pa4B Crystal structure of udp-glucose pyrophosphorylase from corynebacteria glutamicum in complex with magnesium and udp-glucose (see paper)
37% identity, 93% coverage of query (166 bits)
Build an alignment for WP_002719715.1 and 31 homologs with ≥ 30% identity
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Q8YS18 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Nostoc sp. (see paper)
28% identity, 87% coverage of query (105 bits)
agl11 / D4GU70 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL11_HALVD / D4GU70 Low-salt glycan biosynthesis nucleotidyltransferase Agl11; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
28% identity, 86% coverage of query (99.0 bits)
dnmL / C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius subsp. caesius ATCC 27952 (see 2 papers)
C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius (see paper)
28% identity, 82% coverage of query (77.0 bits)
mtmD / Q194R4 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces argillaceus (see paper)
mtmD / CAK50774.1 dTDP-glucose synthase from Streptomyces argillaceus (see 21 papers)
30% identity, 82% coverage of query (76.6 bits)
5z09A St0452(y97n)-utp binding form
26% identity, 82% coverage of query (75.9 bits)
ST0452 / Q975F9 multifunctional glucose-1-phosphate thymidylyltransferase/hexosamine-1-phosphate N-acetyltransferase/UDP-N-acetylhexosamine diphosphorylase (EC 2.7.7.24; EC 2.7.7.23; EC 2.7.7.83; EC 2.3.1.157; EC 2.3.1.276) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see 2 papers)
S1PNA_SULTO / Q975F9 Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase; EC 2.7.7.24; EC 2.7.7.9; EC 2.7.7.83; EC 2.7.7.23; EC 2.3.1.276; EC 2.3.1.157 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 5 papers)
Q975F9 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); galactosamine-1-phosphate N-acetyltransferase (EC 2.3.1.276); UDP-N-acetylglucosamine diphosphorylase (EC 2.7.7.23); glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24); aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37); UDP-N-acetylgalactosamine diphosphorylase (EC 2.7.7.83); UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sulfurisphaera tokodaii (see 7 papers)
2ggqA / Q975F9 Complex of hypothetical glucose-1-phosphate thymidylyltransferase from sulfolobus tokodaii
26% identity, 82% coverage of query (75.5 bits)
GMPPB_PIG / P0C5I2 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase 37-kDa subunit; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Sus scrofa (Pig) (see 2 papers)
30% identity, 83% coverage of query (75.1 bits)
GMPPB_DANRE / Q6DBU5 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q6DBU5 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Danio rerio (see paper)
28% identity, 90% coverage of query (73.2 bits)
oleS / Q9RR29 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces antibioticus (see paper)
OLES_STRAT / Q9RR29 Glucose-1-phosphate thymidylyltransferase; EC 2.7.7.24 from Streptomyces antibioticus (see paper)
25% identity, 82% coverage of query (71.6 bits)
GMPPB_HUMAN / Q9Y5P6 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Homo sapiens (Human) (see 4 papers)
Q9Y5P6 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Homo sapiens (see paper)
7d72K / Q9Y5P6 Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
28% identity, 83% coverage of query (70.9 bits)
7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i)
28% identity, 83% coverage of query (70.9 bits)
7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose
28% identity, 83% coverage of query (70.9 bits)
RMLA_BACSU / P39629 Glucose-1-phosphate thymidylyltransferase; Spore coat polysaccharide biosynthesis protein SpsI; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Bacillus subtilis (strain 168) (see paper)
24% identity, 71% coverage of query (70.5 bits)
Q2HR55 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces sp. (see paper)
25% identity, 82% coverage of query (69.3 bits)
Q400H3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Thermus caldophilus (see paper)
27% identity, 72% coverage of query (68.2 bits)
A0EJL9 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13); mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) from Malpighia glabra (see 2 papers)
26% identity, 90% coverage of query (68.2 bits)
Q9M2S0 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Arabidopsis thaliana (see paper)
28% identity, 71% coverage of query (67.4 bits)
4ho4A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate
26% identity, 82% coverage of query (67.0 bits)
4ho6A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-glucose and utp
26% identity, 82% coverage of query (67.0 bits)
4ho5A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with tdp-glucose
26% identity, 82% coverage of query (67.0 bits)
4ho3A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with thymidine triphosphate
26% identity, 82% coverage of query (67.0 bits)
4ho9A / Q9AGY4 Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-galactose and utp
26% identity, 82% coverage of query (66.6 bits)
4hocA Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-n- acetylglucosamine
25% identity, 82% coverage of query (63.2 bits)
CUGP_SYNY3 / P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
P74285 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Synechocystis sp. (see paper)
25% identity, 82% coverage of query (59.7 bits)
1h5sB / P37744 Thymidylyltransferase complexed with tmp (see paper)
25% identity, 74% coverage of query (59.3 bits)
1h5tA Thymidylyltransferase complexed with thymidylyldiphosphate-glucose
25% identity, 74% coverage of query (59.3 bits)
1h5rA Thymidylyltransferase complexed with thimidine and glucose-1-phospate
25% identity, 74% coverage of query (59.3 bits)
RMLA_SALTY / P26393 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; Ep; dTDP-glucose synthase; EC 2.7.7.24 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
25% identity, 74% coverage of query (58.5 bits)
3hl3A / A0A6L8PCC3 2.76 angstrom crystal structure of a putative glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with a sucrose.
25% identity, 71% coverage of query (56.6 bits)
4ecmA 2.3 angstrom crystal structure of a glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with thymidine-5-diphospho-alpha-d-glucose and pyrophosphate
25% identity, 71% coverage of query (56.6 bits)
3pkpA Q83s variant of s. Enterica rmla with datp
25% identity, 74% coverage of query (56.2 bits)
3pkpB Q83s variant of s. Enterica rmla with datp
25% identity, 74% coverage of query (56.2 bits)
GLMU_HAEIN / P43889 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
P43889 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) from Haemophilus influenzae (see paper)
25% identity, 76% coverage of query (53.5 bits)
RMLA_MYCTU / P9WH13 Glucose-1-phosphate thymidylyltransferase; Glc-1-P thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 5 papers)
P9WH13 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Mycobacterium tuberculosis (see paper)
26% identity, 71% coverage of query (53.1 bits)
6b5eB / P9WH13 Mycobacterium tuberculosis rmla in complex with dtdp-glucose (see paper)
26% identity, 71% coverage of query (52.8 bits)
2v0jA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
26% identity, 75% coverage of query (52.4 bits)
4kqlA Hin glmu bound to wg578
26% identity, 75% coverage of query (52.4 bits)
4kpzA Hin glmu bound to a small molecule fragment
26% identity, 75% coverage of query (52.4 bits)
4kpxA Hin glmu bound to wg766
26% identity, 75% coverage of query (52.4 bits)
4knxA Hin glmu bound to wg176
26% identity, 75% coverage of query (52.4 bits)
4knrA Hin glmu bound to wg188
26% identity, 75% coverage of query (52.4 bits)
4e1kA / P43889 Glmu in complex with a quinazoline compound (see paper)
26% identity, 75% coverage of query (52.4 bits)
2w0wA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 2
26% identity, 75% coverage of query (52.4 bits)
2w0vA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 1
26% identity, 75% coverage of query (52.4 bits)
2vd4A Structure of small-molecule inhibitor of glmu from haemophilus influenzae reveals an allosteric binding site
26% identity, 75% coverage of query (52.4 bits)
2v0lA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
26% identity, 75% coverage of query (52.4 bits)
2v0kA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
26% identity, 75% coverage of query (52.4 bits)
2v0iA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu)
26% identity, 75% coverage of query (52.4 bits)
6b5kA Mycobacterium tuberculosis rmla in complex with mg/dttp
25% identity, 71% coverage of query (51.6 bits)
1lvwA / O27819 Crystal structure of glucose-1-phosphate thymidylyltransferase, rmla, complex with dtdp
24% identity, 82% coverage of query (51.2 bits)
4fceA / Q8Z9S7 Crystal structure of yersinia pestis glmu in complex with alpha-d- glucosamine 1-phosphate (gp1)
25% identity, 89% coverage of query (43.9 bits)
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Lawrence Berkeley National Laboratory