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Searching for up to 100 curated homologs for WP_002968065.1 NCBI__GCF_000022745.1:WP_002968065.1 (662 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMc00774 Acetoacetate--CoA ligase (EC 6.2.1.16) from Sinorhizobium meliloti 1021
AACS_RHIME / Q9Z3R3 Acetoacetyl-coenzyme A synthetase; Acetoacetyl-CoA synthetase; EC 6.2.1.16 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
Q9Z3R3 acetoacetate-CoA ligase (EC 6.2.1.16) from Sinorhizobium meliloti (see paper)
    70% identity, 98% coverage of query (939 bits)

acsA / AAC64548.1 acetoacetyl-CoA synthetase from Sinorhizobium meliloti (see paper)
    69% identity, 98% coverage of query (936 bits)

AACS_MOUSE / Q9D2R0 Acetoacetyl-CoA synthetase; EC 6.2.1.16 from Mus musculus (Mouse) (see paper)
Q9D2R0 acetoacetate-CoA ligase (EC 6.2.1.16) from Mus musculus (see 2 papers)
    47% identity, 97% coverage of query (599 bits)

AACS_RAT / Q9JMI1 Acetoacetyl-CoA synthetase; EC 6.2.1.16 from Rattus norvegicus (Rat) (see 4 papers)
Q9JMI1 acetoacetyl-CoA synthase (EC 2.3.1.194) from Rattus norvegicus (see paper)
    46% identity, 97% coverage of query (595 bits)

AACS_HUMAN / Q86V21 Acetoacetyl-CoA synthetase; Acyl-CoA synthetase family member 1; Protein sur-5 homolog; EC 6.2.1.16 from Homo sapiens (Human) (see paper)
    47% identity, 97% coverage of query (594 bits)

aacS / D6EQU8 acetoacetate-CoA ligase (EC 6.2.1.16) from Streptomyces lividans TK24 (see 2 papers)
D6EQU8 acetoacetate-CoA ligase (EC 6.2.1.16) from Streptomyces lividans (see paper)
    44% identity, 99% coverage of query (541 bits)

acsA / Q5P8R9 4-hydroxybenzoyl-acetyl-CoA synthetase from Aromatoleum aromaticum (strain EbN1) (see paper)
    44% identity, 98% coverage of query (536 bits)

4wd1A / D6EQU8 Acetoacetyl-coa synthetase from streptomyces lividans (see paper)
    44% identity, 97% coverage of query (533 bits)

SUR5_CAEEL / Q21166 Acetoacetyl-CoA synthetase; Suppressor of activated let-60 Ras protein 5; EC 6.2.1.16 from Caenorhabditis elegans (see paper)
    39% identity, 95% coverage of query (461 bits)

VrtB / D7PHZ3 malonamate-CoA ligase from Penicillium aethiopicum (see paper)
VRTB_PENAE / D7PHZ3 Malonamoyl-CoA synthetase vrtB; Viridicatumtoxin synthesis protein B; EC 6.2.1.- from Penicillium aethiopicum (see 4 papers)
    38% identity, 97% coverage of query (438 bits)

Build an alignment

Build an alignment for WP_002968065.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

A4YGF9 4-hydroxybutyrate-CoA ligase (AMP-forming) (EC 6.2.1.40) from Metallosphaera sedula (see paper)
    29% identity, 93% coverage of query (215 bits)

ACSA_METTP / A0B8F1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanosaeta thermophila) (see paper)
A0B8F1 acetate-CoA ligase (EC 6.2.1.1) from Methanothrix thermoacetophila (see paper)
    30% identity, 85% coverage of query (211 bits)

Q2XNL6 acetate-CoA ligase (EC 6.2.1.1) from Methanothermobacter thermautotrophicus (see paper)
    28% identity, 84% coverage of query (208 bits)

ACSA_MYCTU / P9WQD1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    30% identity, 92% coverage of query (206 bits)

8rplB / A0A535FEC2 Amp-forming acetyl-coa synthetase from chloroflexota bacterium with bound acetyl amp (see paper)
    26% identity, 88% coverage of query (205 bits)

Q2I0L7 acetate-CoA ligase (EC 6.2.1.1) from Methanothermobacter thermautotrophicus (see paper)
    28% identity, 84% coverage of query (204 bits)

Q89WV5 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
    26% identity, 91% coverage of query (202 bits)

ACSA_MYCS2 / A0R5G1 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    28% identity, 90% coverage of query (196 bits)

HPCAS_SULTO / Q973W5 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q973W5 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36) from Sulfurisphaera tokodaii (see paper)
    29% identity, 94% coverage of query (196 bits)

2p20A / Q8ZKF6 Acetyl-coa synthetase, r584a mutation (see paper)
    28% identity, 91% coverage of query (192 bits)

AcsA / b4069 acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.1; EC 6.2.1.17) from Escherichia coli K-12 substr. MG1655 (see 48 papers)
acs / P27550 acetyl-CoA synthetase (AMP-forming) (EC 6.2.1.17; EC 6.2.1.1) from Escherichia coli (strain K12) (see 46 papers)
ACSA_ECOLI / P27550 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Escherichia coli (strain K12) (see 3 papers)
    27% identity, 91% coverage of query (192 bits)

5jrhA Crystal structure of salmonella enterica acetyl-coa synthetase (acs) in complex with camp and coenzyme a
    28% identity, 91% coverage of query (192 bits)

ACSA_SALTY / Q8ZKF6 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 5 papers)
    28% identity, 91% coverage of query (191 bits)

acs1 / Q2LWR8 acetate—CoA ligase (EC 6.2.1.1) from Syntrophus aciditrophicus (strain SB) (see paper)
    27% identity, 92% coverage of query (191 bits)

2p2fA Acetyl-coa synthetase, wild-type with acetate, amp, and coa bound
    28% identity, 91% coverage of query (191 bits)

Msed_1456 / A4YGR1 3-hydroxypropionyl-CoA synthetase subunit (EC 6.2.1.36) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 2 papers)
HPCAS_METS5 / A4YGR1 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
A4YGR1 propionate-CoA ligase (EC 6.2.1.17); 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36) from Metallosphaera sedula (see 2 papers)
    28% identity, 93% coverage of query (190 bits)

P78773 Probable acetyl-coenzyme A synthetase; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    27% identity, 92% coverage of query (190 bits)

1pg3A Acetyl coa synthetase, acetylated on lys609
    28% identity, 91% coverage of query (186 bits)

AO356_18695 Acetyl-coenzyme A synthetase (EC 6.2.1.1) from Pseudomonas fluorescens FW300-N2C3
    26% identity, 92% coverage of query (184 bits)

AO353_03060 Acetyl-coenzyme A synthetase (EC 6.2.1.1) from Pseudomonas fluorescens FW300-N2E3
    26% identity, 95% coverage of query (182 bits)

acsA / P31638 acetyl-CoA synthetase (EC 6.2.1.1; EC 6.2.1.17) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
ACSA_CUPNH / P31638 Acetyl-coenzyme A synthetase; AcCoA synthetase; Acs; Acetate--CoA ligase; Acyl-activating enzyme; EC 6.2.1.1 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
    26% identity, 92% coverage of query (181 bits)

ACS1 / Q01574 acetyl CoA synthetase 1 (EC 6.2.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
ACS1_YEAST / Q01574 Acetyl-coenzyme A synthetase 1; Acetate--CoA ligase 1; Acyl-activating enzyme 1; EC 6.2.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    27% identity, 93% coverage of query (180 bits)

8rwjD / N1P7N2 Cryoem structure of acs1 filament determined by filamentid (see paper)
    27% identity, 93% coverage of query (180 bits)

facA acetyl-coenzyme A synthetase; EC 6.2.1.1 from Emericella nidulans (see 2 papers)
    25% identity, 97% coverage of query (179 bits)

ACS_ARATH / B9DGD6 Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Acetate--CoA ligase; Acetyl-CoA synthetase; EC 6.2.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
B9DGD6 acetate-CoA ligase (EC 6.2.1.1) from Arabidopsis thaliana (see paper)
    24% identity, 91% coverage of query (178 bits)

ACS2L_MOUSE / Q99NB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial; Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; AceCS2; Acyl-CoA synthetase short-chain family member 1; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Mus musculus (Mouse) (see 3 papers)
Q99NB1 acetate-CoA ligase (EC 6.2.1.1) from Mus musculus (see paper)
    26% identity, 91% coverage of query (176 bits)

ACS2L_HUMAN / Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial; Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; AceCS2; Acyl-CoA synthetase short-chain family member 1; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human) (see 2 papers)
Q9NUB1 acetate-CoA ligase (EC 6.2.1.1) from Homo sapiens (see paper)
    27% identity, 93% coverage of query (175 bits)

1ry2A Crystal structure of yeast acetyl-coenzyme a synthetase in complex with amp
    27% identity, 93% coverage of query (175 bits)

ACAS2 / Q9NR19 acetyl-coA synthetase (EC 6.2.1.1) from Homo sapiens (see 2 papers)
ACSA_HUMAN / Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human) (see 3 papers)
Q9NR19 acetate-CoA ligase (EC 6.2.1.1) from Homo sapiens (see 5 papers)
    26% identity, 92% coverage of query (173 bits)

ACS2 / P52910 acetyl CoA synthetase 2 (EC 6.2.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ACS2_YEAST / P52910 Acetyl-coenzyme A synthetase 2; Acetate--CoA ligase 2; Acyl-activating enzyme 2; EC 6.2.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P52910 acetate-CoA ligase (EC 6.2.1.1) from Saccharomyces cerevisiae (see paper)
    26% identity, 85% coverage of query (172 bits)

B1YBY4 4-hydroxybutyrate-CoA ligase (AMP-forming) (EC 6.2.1.40) from Pyrobaculum neutrophilum (see 2 papers)
    27% identity, 90% coverage of query (171 bits)

7l4gB / J9VFT1 Crystal structure of acetyl-coa synthetase in complex with acetyl adenylate from cryptococcus neoformans h99
    27% identity, 85% coverage of query (171 bits)

A0A144QFN1 acetate-CoA ligase (EC 6.2.1.1) from Dunaliella tertiolecta (see paper)
    26% identity, 91% coverage of query (171 bits)

5u29A Crystal structure of cryptococcus neoformans h99 acetyl-coa synthetase in complex with ac-ams
    27% identity, 85% coverage of query (171 bits)

8w0bA / Q8NJN3 Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a cyclopropyl amp ester inhibitor
    24% identity, 96% coverage of query (169 bits)

ACS2 acetyl-coenzyme A synthetase 2; EC 6.2.1.1 from Candida albicans (see 2 papers)
    24% identity, 96% coverage of query (169 bits)

8w0dA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with an isopropyl amp ester inhibitor
    24% identity, 96% coverage of query (169 bits)

8v4rA Crystal structure of acetyl-coa synthetase 2 in complex with amp and coa from candida albicans
    24% identity, 96% coverage of query (169 bits)

8w0cA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a cyclopentyl ester amp inhibitor
    24% identity, 96% coverage of query (169 bits)

5k8fA Crystal structure of acetyl-coa synthetase in complex with atp and acetyl-amp from cryptococcus neoformans h99
    28% identity, 83% coverage of query (167 bits)

8w0jA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a propyne amp ester inhibitor
    24% identity, 96% coverage of query (166 bits)

8v4pA Crystal structure of acetyl-coa synthetase 2 in complex with adenosine-5'-allylphosphate from candida albicans
    24% identity, 96% coverage of query (166 bits)

8v4oA Crystal structure of acetyl-coa synthetase 2 in complex with amp from candida albicans
    24% identity, 96% coverage of query (166 bits)

7kdsA Crystal structure of acetyl-coa synthetase 2 in complex with adenosine-5'-propylphosphate from candida albicans
    25% identity, 96% coverage of query (165 bits)

8g0vA Crystal structure of acetyl-coa synthetase in complex with a propyne ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 85% coverage of query (164 bits)

8g0uA Crystal structure of acetyl-coa synthetase in complex with an isopropyl ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 85% coverage of query (164 bits)

7knoA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-ethylphosphate from cryptococcus neoformans var. Grubii serotype a (h99)
    27% identity, 85% coverage of query (164 bits)

8g0tA Crystal structure of acetyl-coa synthetase in complex with a cyclopropyl ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 85% coverage of query (162 bits)

ACSA_MOUSE / Q9QXG4 Acetyl-coenzyme A synthetase, cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Mus musculus (Mouse) (see 4 papers)
    25% identity, 92% coverage of query (161 bits)

8v5gA Crystal structure of acetyl-coa synthetase from cryptococcus neoformans h99 in complex with an ethylsulfamide amp inhibitor
    28% identity, 82% coverage of query (161 bits)

7knpA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-butylphosphate from cryptococcus neoformans var. Grubii serotype a (h99)
    27% identity, 83% coverage of query (160 bits)

5ifiA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from cryptococcus neoformans h99
    27% identity, 83% coverage of query (157 bits)

8g0rA Crystal structure of acetyl-coa synthetase in complex with a cyclopentyl ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 83% coverage of query (156 bits)

5k8fC Crystal structure of acetyl-coa synthetase in complex with atp and acetyl-amp from cryptococcus neoformans h99
    27% identity, 83% coverage of query (155 bits)

8epsA Crystal structure of acetyl-coa synthetase in complex with an allyl ester amp inhibitor from cryptococcus neoformans h99
    27% identity, 82% coverage of query (155 bits)

7kvyA / J3KJC6 Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-ethylphosphate and co-enzyme a from coccidioides immitis rs
    25% identity, 89% coverage of query (146 bits)

7mmzA / Q5ZZ84 Crystal structure of acetyl-coenzyme a synthetase from legionella pneumophila philadelphia 1 in complex with ethyl-amp (see paper)
    26% identity, 78% coverage of query (145 bits)

5k85C Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate and coenzyme a from cryptococcus neoformans h99
    27% identity, 78% coverage of query (144 bits)

8sf3A Crystal structure of acetyl-coenzyme a synthetase from leishmania infantum (amp, acetate and coa bound)
    24% identity, 93% coverage of query (143 bits)

7l3qA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-methylphosphate and co-enzyme a from coccidioides immitis rs
    26% identity, 88% coverage of query (143 bits)

8u2rA / A4I093 Crystal structure of acetyl-coenzyme a synthetase from leishmania infantum (ethyl amp bound) (see paper)
    24% identity, 93% coverage of query (142 bits)

8w0mA Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a acetyl sulfamate amp ester inhibitor
    24% identity, 89% coverage of query (141 bits)

7kdnA / Q4WQ02 Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from aspergillus fumigatus
    25% identity, 80% coverage of query (141 bits)

8w0lC Crystal structure of acetyl-coa synthetase 2 from candida albicans in complex with a propyne amp ester inhibitor and coa
    24% identity, 86% coverage of query (140 bits)

7kcpA Crystal structure of acetyl-coa synthetase in complex with adenosine- 5'-propylphosphate from coccidioides posadasii c735
    25% identity, 76% coverage of query (130 bits)

5gxdA / A8LRC0 Structure of acryloyl-coa lyase prpe from dinoroseobacter shibae dfl 12
    24% identity, 90% coverage of query (124 bits)

3dayA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with amp-cpp
    24% identity, 81% coverage of query (82.0 bits)

3b7wA / Q08AH3 Crystal structure of human acyl-coa synthetase medium-chain family member 2a, with l64p mutation (see paper)
    24% identity, 81% coverage of query (79.7 bits)

3c5eA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with atp
    24% identity, 81% coverage of query (79.3 bits)

3eq6A Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in a ternary complex with products
    24% identity, 81% coverage of query (79.3 bits)

2wd9A Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with ibuprofen
    24% identity, 81% coverage of query (79.3 bits)

2vzeA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with amp
    24% identity, 81% coverage of query (79.3 bits)

ACS2A_HUMAN / Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial; Acyl-CoA synthetase medium-chain family member 2A; Benzoate--CoA ligase; Butyrate--CoA ligase 2A; Butyryl-coenzyme A synthetase 2A; Middle-chain acyl-CoA synthetase 2A; EC 6.2.1.2; EC 6.2.1.25 from Homo sapiens (Human) (see paper)
    24% identity, 81% coverage of query (77.8 bits)

8bitA Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with coenzyme a and acetyl-amp
    22% identity, 80% coverage of query (75.9 bits)

8biqA / A4YDT1 Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with acetyl-amp
    22% identity, 80% coverage of query (75.9 bits)

8biqB Crystal structure of acyl-coa synthetase from metallosphaera sedula in complex with acetyl-amp
    22% identity, 80% coverage of query (75.9 bits)

FAC13_MYCTU / P9WQ37 Long-chain-fatty-acid--CoA ligase FadD13; Fatty acyl-CoA ligase; FACL; FACL13; Fatty acyl-CoA synthetase; ACS; FACS; Very-long-chain fatty-acyl-CoA synthetase; ACSVL; EC 6.2.1.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 7 papers)
    24% identity, 78% coverage of query (72.4 bits)

3gpcA Crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in a complex with coa
    24% identity, 81% coverage of query (72.0 bits)

dhbE / P40871 DhbE monomer (EC 6.2.1.71) from Bacillus subtilis (strain 168) (see paper)
DHBE_BACSU / P40871 2,3-dihydroxybenzoate-AMP ligase; Dihydroxybenzoic acid-activating enzyme; EC 6.2.1.71 from Bacillus subtilis (strain 168) (see paper)
    22% identity, 77% coverage of query (71.6 bits)

1md9A / P40871 Crystal structure of dhbe in complex with dhb and amp (see paper)
    22% identity, 77% coverage of query (69.3 bits)

4CL2 / Q9S725 4-coumarate coenzyme A ligase 2 (EC 6.2.1.12) from Arabidopsis thaliana (see 2 papers)
4CL2_ARATH / Q9S725 4-coumarate--CoA ligase 2; 4CL 2; 4-coumarate--CoA ligase isoform 2; At4CL2; 4-coumaroyl-CoA synthase 2; Caffeate--CoA ligase; EC 6.2.1.12; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9S725 4-coumarate-CoA ligase (EC 6.2.1.12) from Arabidopsis thaliana (see 3 papers)
    23% identity, 76% coverage of query (66.2 bits)

5n9xA / H6SG27 Structure of adenylation domain thr1 involved in the biosynthesis of 4-chlorothreonine in streptomyces sp.Oh-5093, ligand bound structure (see paper)
    24% identity, 76% coverage of query (62.8 bits)

8wwwA / A0A124HF73 Crystal structure of the adenylation domain of syastc
    22% identity, 76% coverage of query (62.4 bits)

3r44A / P9WQ37 Mycobacterium tuberculosis fatty acyl coa synthetase (see paper)
    23% identity, 78% coverage of query (62.0 bits)

5n9xB Structure of adenylation domain thr1 involved in the biosynthesis of 4-chlorothreonine in streptomyces sp.Oh-5093, ligand bound structure
    23% identity, 76% coverage of query (57.8 bits)

AAE3 / Q9SMT7 oxalate--CoA ligase (EC 6.2.1.8) from Arabidopsis thaliana (see 4 papers)
4CLLA_ARATH / Q9SMT7 Oxalate--CoA ligase; 4-coumarate--CoA ligase isoform 8; At4CL8; 4-coumarate--CoA ligase-like 10; Acyl-activating enzyme 3; Adenosine monophosphate binding protein 3; AtMPBP3; Oxalyl-CoA synthetase; EC 6.2.1.8 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9SMT7 oxalate-CoA ligase (EC 6.2.1.8) from Arabidopsis thaliana (see 2 papers)
    23% identity, 79% coverage of query (57.4 bits)

INLPC_MYCTU / P9WQ55 Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase FadD10; FAAL10; EC 6.2.1.20; EC 6.2.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
    23% identity, 78% coverage of query (57.0 bits)

3rg2C / P0ADI4,P10378 Structure of a two-domain nrps fusion protein containing the ente adenylation domain and entb aryl-carrier protein from enterobactin biosynthesis (see paper)
    21% identity, 84% coverage of query (53.5 bits)

5ie2A / Q9SMT7 Crystal structure of a plant enzyme (see paper)
    23% identity, 79% coverage of query (53.1 bits)

3ni2A Crystal structures and enzymatic mechanisms of a populus tomentosa 4- coumarate:coa ligase
    22% identity, 76% coverage of query (52.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory