Searching for up to 100 curated homologs for WP_004040879.1 NCBI__GCF_000337315.1:WP_004040879.1 (564 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
32% identity, 97% coverage of query (261 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
31% identity, 97% coverage of query (233 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
32% identity, 100% coverage of query (229 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
31% identity, 100% coverage of query (224 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
31% identity, 94% coverage of query (215 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
33% identity, 92% coverage of query (209 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
31% identity, 98% coverage of query (207 bits)
A0A1X9M8K4 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Alkalihalobacillus krulwichiae (see paper)
30% identity, 97% coverage of query (205 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
31% identity, 98% coverage of query (202 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
31% identity, 95% coverage of query (202 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
31% identity, 95% coverage of query (198 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
30% identity, 95% coverage of query (197 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
30% identity, 97% coverage of query (195 bits)
Build an alignment for WP_004040879.1 and 13 homologs with ≥ 30% identity
Or download the sequences
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
28% identity, 97% coverage of query (190 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
30% identity, 95% coverage of query (181 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
30% identity, 93% coverage of query (178 bits)
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
27% identity, 98% coverage of query (178 bits)
als / CAA66718.1 acetolactate synthase from Synechocystis sp (see paper)
28% identity, 97% coverage of query (177 bits)
G4MMK2 acetolactate synthase (subunit 1/2) (EC 2.2.1.6) from Pyricularia oryzae (see paper)
28% identity, 95% coverage of query (174 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
27% identity, 95% coverage of query (174 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
27% identity, 95% coverage of query (173 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
27% identity, 95% coverage of query (173 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
27% identity, 95% coverage of query (173 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
27% identity, 95% coverage of query (173 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
27% identity, 95% coverage of query (172 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
27% identity, 95% coverage of query (172 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
27% identity, 95% coverage of query (171 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
27% identity, 95% coverage of query (171 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
27% identity, 95% coverage of query (171 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
28% identity, 96% coverage of query (170 bits)
7egvA Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
28% identity, 96% coverage of query (169 bits)
AN4956 acetolactate synthase; EC 2.2.1.6 from Emericella nidulans (see paper)
28% identity, 95% coverage of query (169 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
27% identity, 96% coverage of query (169 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
27% identity, 96% coverage of query (169 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
27% identity, 96% coverage of query (169 bits)
CFOL_ASPCN / A0A2I2F2I5 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; Chlorflavonin biosynthesis cluster protein L; EC 2.2.1.6 from Aspergillus candidus (see paper)
28% identity, 94% coverage of query (168 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
27% identity, 95% coverage of query (168 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
27% identity, 96% coverage of query (168 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
27% identity, 95% coverage of query (168 bits)
xsc / Q93PS3 sulfoacetaldehyde acetyltransferase subunit (EC 2.3.3.15) from Desulfonispora thiosulfatigenes (see 2 papers)
28% identity, 96% coverage of query (167 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
27% identity, 96% coverage of query (167 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
27% identity, 96% coverage of query (167 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
28% identity, 96% coverage of query (166 bits)
Q0K022 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Cupriavidus necator (see paper)
29% identity, 96% coverage of query (166 bits)
ILV2 acetolactate synthase; EC 2.2.1.6 from Candida albicans (see paper)
27% identity, 95% coverage of query (166 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
27% identity, 95% coverage of query (166 bits)
PS417_08810 glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas simiae WCS417
27% identity, 97% coverage of query (164 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
27% identity, 95% coverage of query (163 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
27% identity, 95% coverage of query (162 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
26% identity, 95% coverage of query (162 bits)
xsc / Q84H44 sulfoacetaldehyde acetyltransferase monomer (EC 2.3.3.15) from Castellaniella defragrans (see paper)
XSC_CASDE / Q84H44 Sulfoacetaldehyde acetyltransferase; EC 2.3.3.15 from Castellaniella defragrans (Alcaligenes defragrans) (see paper)
Q84H44 sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) from Castellaniella defragrans (see paper)
29% identity, 94% coverage of query (161 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
27% identity, 97% coverage of query (161 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
29% identity, 97% coverage of query (161 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
26% identity, 95% coverage of query (161 bits)
ilv1 / RF|NP_595382.1 acetolactate synthase catalytic subunit; EC 2.2.1.6 from Schizosaccharomyces pombe (see 2 papers)
27% identity, 94% coverage of query (160 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
27% identity, 90% coverage of query (159 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
28% identity, 96% coverage of query (158 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
28% identity, 96% coverage of query (158 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
28% identity, 96% coverage of query (157 bits)
PoxB / b0871 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli K-12 substr. MG1655 (see 70 papers)
poxB / P07003 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli (strain K12) (see 69 papers)
POXB_ECOLI / P07003 Pyruvate dehydrogenase [ubiquinone]; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductase; EC 1.2.5.1 from Escherichia coli (strain K12) (see 13 papers)
P07003 pyruvate dehydrogenase (quinone) (EC 1.2.5.1) from Escherichia coli (see paper)
29% identity, 96% coverage of query (154 bits)
3ey9A / P07003 Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from escherichia coli (see paper)
29% identity, 96% coverage of query (154 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
28% identity, 85% coverage of query (153 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
28% identity, 85% coverage of query (153 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
26% identity, 95% coverage of query (153 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
26% identity, 95% coverage of query (153 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
28% identity, 85% coverage of query (152 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
28% identity, 85% coverage of query (152 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
28% identity, 85% coverage of query (152 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
28% identity, 85% coverage of query (152 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
28% identity, 85% coverage of query (152 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
28% identity, 85% coverage of query (152 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
28% identity, 85% coverage of query (152 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
28% identity, 85% coverage of query (152 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
28% identity, 85% coverage of query (152 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
28% identity, 85% coverage of query (152 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
28% identity, 85% coverage of query (152 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
28% identity, 85% coverage of query (152 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
28% identity, 85% coverage of query (151 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase (see paper)
26% identity, 95% coverage of query (151 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
28% identity, 85% coverage of query (151 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 95% coverage of query (151 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 95% coverage of query (151 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
28% identity, 96% coverage of query (150 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
28% identity, 96% coverage of query (147 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
28% identity, 85% coverage of query (147 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
28% identity, 96% coverage of query (147 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
28% identity, 96% coverage of query (147 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
28% identity, 96% coverage of query (146 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
27% identity, 98% coverage of query (146 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
27% identity, 98% coverage of query (145 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
28% identity, 96% coverage of query (144 bits)
7b2eA / C5AX46 Quadruple mutant of oxalyl-coa decarboxylase from methylorubrum extorquens with bound tpp and adp (see paper)
27% identity, 95% coverage of query (134 bits)
4d5eB / P0CH62 Crystal structure of recombinant wildtype cdh (see paper)
26% identity, 97% coverage of query (133 bits)
2pgnA The crystal structure of fad and thdp-dependent cyclohexane-1,2-dione hydrolase in complex with cyclohexane-1,2-dione
26% identity, 97% coverage of query (133 bits)
HACL_ACTC0 / P0DUV9 2-hydroxyacyl-CoA lyase; AcHACL; HACL; 2-hydroxyisobutyryl-CoA lyase; EC 4.1.-.- from Actinomycetospora chiangmaiensis (strain DSM 45062 / JCM 15998 / CCTCC AA 205017 / NBRC 104400 / YIM 0006) (see 2 papers)
28% identity, 94% coverage of query (131 bits)
7pt4A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone
28% identity, 96% coverage of query (131 bits)
7pt4B / P0DUV9 Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone (see paper)
28% identity, 96% coverage of query (130 bits)
7pt1A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with substrate 2-hib-coa and inactive cofactor 3-deaza-thdp
28% identity, 96% coverage of query (130 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
24% identity, 95% coverage of query (126 bits)
1v5gA Crystal structure of the reaction intermediate between pyruvate oxidase containing fad and tpp, and substrate pyruvate
25% identity, 99% coverage of query (124 bits)
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Lawrence Berkeley National Laboratory