Searching for up to 100 curated homologs for WP_004045055.1 NCBI__GCF_000337315.1:WP_004045055.1 (291 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3vpdA / Q5SH23 Lysx from thermus thermophilus complexed with amp-pnp (see paper)
    44% identity, 96% coverage of query (254 bits)

lysX / Q5SH23 L-2-aminoadipate--LysW ligase monomer (EC 6.3.2.43) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
LYSX_THET8 / Q5SH23 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
Q5SH23 [amino group carrier protein]-L-2-aminoadipate ligase (EC 6.3.2.43) from Thermus thermophilus (see 2 papers)
    44% identity, 94% coverage of query (254 bits)

Q5JFW0 lysyltransferase (EC 2.3.2.3); [amino group carrier protein]-L-2-aminoadipate ligase (EC 6.3.2.43); glutamate---[amino group carrier protein] ligase (EC 6.3.2.60) from Thermococcus kodakarensis (see paper)
5k2mG / Q5JFW0 Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa (see paper)
    38% identity, 95% coverage of query (178 bits)

5k2mI Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa
    38% identity, 95% coverage of query (178 bits)

1uc9A / Q5SH23 Crystal structure of a lysine biosynthesis enzyme, lysx, from thermus thermophilus hb8 (see paper)
    37% identity, 94% coverage of query (177 bits)

LYSX_SACS2 / Q7SI95 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
    35% identity, 85% coverage of query (154 bits)

argX / Q4J8E7 glutamate--LysW ligase monomer (EC 6.3.2.60) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
ARGX_SULAC / Q4J8E7 Glutamate--LysW ligase ArgX; EC 6.3.2.- from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J8E7 glutamate---[amino group carrier protein] ligase (EC 6.3.2.60) from Sulfolobus acidocaldarius (see paper)
    30% identity, 95% coverage of query (154 bits)

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Build an alignment for WP_004045055.1 and 7 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ARGX_SULTO / Q970U6 Glutamate--LysW ligase ArgX; EC 6.3.2.- from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
3vpbB / Q970U6 Argx from sulfolobus tokodaii complexed with lysw/glu/adp/mg/zn/sulfate (see paper)
    29% identity, 95% coverage of query (148 bits)

LYSX_SULAC / Q4JAP9 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4JAP9 [amino group carrier protein]-L-2-aminoadipate ligase (EC 6.3.2.43) from Sulfolobus acidocaldarius (see paper)
    31% identity, 86% coverage of query (136 bits)

7qyrD / Q9HTZ2 Crystal structure of rimk from pseudomonas aeruginosa pao1 (see paper)
    25% identity, 93% coverage of query (79.3 bits)

cofF / Q58407 γ-F420-2:α-L-glutamate ligase (EC 6.3.2.32) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
COFF_METJA / Q58407 Coenzyme gamma-F420-2:alpha-L-glutamate ligase; EC 6.3.2.32 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58407 coenzyme gamma-F420-2:alpha-L-glutamate ligase (EC 6.3.2.32) from Methanocaldococcus jannaschii (see paper)
    27% identity, 83% coverage of query (73.6 bits)

RIMKA_MOUSE / Q6PFX8 N-acetylaspartylglutamate synthase A; NAAG synthetase A; NAAGS; N-acetylaspartylglutamylglutamate synthase A; Ribosomal protein S6 modification-like protein A; EC 6.3.2.41; EC 6.3.2.42 from Mus musculus (Mouse) (see 2 papers)
Q6PFX8 N-acetylaspartylglutamate synthase (EC 6.3.2.41); N-acetylaspartylglutamylglutamate synthase (EC 6.3.2.42) from Mus musculus (see 2 papers)
    30% identity, 77% coverage of query (70.5 bits)

Nek / b0852 ribosomal protein S6 modification protein from Escherichia coli K-12 substr. MG1655 (see 3 papers)
rimK / P0C0U4 ribosomal protein S6 modification protein from Escherichia coli (strain K12) (see 6 papers)
RIMK_ECOLI / P0C0U4 Ribosomal protein bS6--L-glutamate ligase; Polyglutamate synthase; Ribosomal protein bS6 modification protein; EC 6.3.2.- from Escherichia coli (strain K12) (see 2 papers)
    24% identity, 95% coverage of query (67.0 bits)

4iwxA / P0C0U4 Rimk structure at 2.85a (see paper)
    24% identity, 95% coverage of query (67.0 bits)

5zctH The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution.
    24% identity, 95% coverage of query (66.6 bits)

5zctA The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution.
    24% identity, 95% coverage of query (66.6 bits)

RIMKB_MOUSE / Q80WS1 Beta-citrylglutamate synthase B; N-acetyl-aspartylglutamate synthetase B; NAAG synthetase B; NAAGS; Ribosomal protein S6 modification-like protein B; EC 6.3.1.17; EC 6.3.2.41 from Mus musculus (Mouse) (see 2 papers)
Q80WS1 beta-citrylglutamate synthase (EC 6.3.1.17); N-acetylaspartylglutamate synthase (EC 6.3.2.41) from Mus musculus (see 2 papers)
    27% identity, 73% coverage of query (57.8 bits)

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