Searching for up to 100 curated homologs for WP_004321104.1 NCBI__GCF_000310185.1:WP_004321104.1 (255 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4xgnA / Q2T0K5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase in complex with NAD from burkholderia thailandensis
69% identity, 100% coverage of query (322 bits)
4o5oB / A0A0H3G6B0 X-ray crystal structure of a 3-hydroxyacyl-coa dehydrogenase from brucella suis
65% identity, 100% coverage of query (312 bits)
fadB2x / Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
63% identity, 100% coverage of query (306 bits)
HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxyacyl-CoA dehydrogenase type II; Hydroxysteroid dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.62; EC 1.1.1.-; EC 1.1.1.53 from Drosophila melanogaster (Fruit fly) (see 7 papers)
57% identity, 98% coverage of query (268 bits)
1u7tA Crystal structure of abad/hsd10 with a bound inhibitor
55% identity, 96% coverage of query (248 bits)
8cbkC / Q99714 Structure of human mitochondrial rnase p in complex with mitochondrial pre-tRNA-his(5,ser) (see paper)
55% identity, 96% coverage of query (246 bits)
HSD17B10 / Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35; EC 1.1.1.178; EC 1.1.1.239) from Homo sapiens (see 3 papers)
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Homo sapiens (Human) (see 22 papers)
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Homo sapiens (see 2 papers)
55% identity, 96% coverage of query (246 bits)
1uayA / Q7SIA1 Crystal structure of type ii 3-hydroxyacyl-coa dehydrogenase from thermus thermophilus hb8
57% identity, 97% coverage of query (245 bits)
O70351 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Rattus norvegicus (Rat)
53% identity, 96% coverage of query (245 bits)
1e3wD / O70351 Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate (see paper)
53% identity, 96% coverage of query (244 bits)
HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Mus musculus (Mouse) (see paper)
53% identity, 96% coverage of query (243 bits)
6ujkA / P9WGQ7 Crystal structure of a probable short-chain type dehydrogenase/reductase (rv1144) from mycobacterium tuberculosis with bound NAD
55% identity, 100% coverage of query (242 bits)
1e6wC Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol
52% identity, 96% coverage of query (233 bits)
7n09A / F1L0H2 Structural basis for branched substrate selectivity in a ketoreductase from ascaris suum
46% identity, 97% coverage of query (199 bits)
3ppiA / A0A0H3A4S5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from mycobacterium avium (see paper)
46% identity, 97% coverage of query (198 bits)
IDOLDH / G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see paper)
IDLDH_IPSPI / G5DGA8 Ipsdienol dehydrogenase; EC 1.1.1.386 from Ips pini (Pine engraver beetle) (see paper)
G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see 2 papers)
39% identity, 98% coverage of query (165 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
36% identity, 98% coverage of query (140 bits)
SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
38% identity, 99% coverage of query (129 bits)
1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
39% identity, 88% coverage of query (116 bits)
1nfqA Rv2002 gene product from mycobacterium tuberculosis
39% identity, 88% coverage of query (116 bits)
HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
38% identity, 88% coverage of query (115 bits)
BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
34% identity, 97% coverage of query (108 bits)
PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
32% identity, 97% coverage of query (108 bits)
5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
32% identity, 99% coverage of query (106 bits)
7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
34% identity, 97% coverage of query (106 bits)
LINX_SPHIU / D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
35% identity, 97% coverage of query (105 bits)
Ira5 / Q1NEI6 L-2-keto-3-deoxyrhamnonate 4-dehydrogenase subunit (EC 1.1.1.401) from Sphingomonas sp. (strain SKA58) (see paper)
KDRDH_SPHSS / Q1NEI6 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD(+)); 2-keto-3-deoxy-L-rhamnonate dehydrogenase; KDRDH; L-KDR dehydrogenase; L-KDR 4-dehydrogenase; EC 1.1.1.401 from Sphingomonas sp. (strain SKA58) (see paper)
Q1NEI6 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) (EC 1.1.1.401) from Sphingomonas sp. (see paper)
38% identity, 87% coverage of query (104 bits)
ABA4_BOTFB / A0A384JQF5 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
31% identity, 98% coverage of query (104 bits)
4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
34% identity, 90% coverage of query (104 bits)
4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
34% identity, 90% coverage of query (104 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
31% identity, 97% coverage of query (103 bits)
6zyzA Structure of the borneol dehydrogenases of salvia rosmarinus with NAD+ (see paper)
36% identity, 75% coverage of query (103 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
31% identity, 97% coverage of query (103 bits)
E5DD06 (+)-borneol dehydrogenase (EC 1.1.1.198) from Artemisia annua (see paper)
35% identity, 77% coverage of query (103 bits)
hsd / P19871 3β-hydroxysteroid dehydrogenase monomer (EC 1.1.1.51) from Comamonas testosteroni (see 7 papers)
3BHD_COMTE / P19871 3-beta-hydroxysteroid dehydrogenase; EC 1.1.1.51 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
34% identity, 98% coverage of query (103 bits)
LINC_SPHIU / D4YYG1 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
34% identity, 88% coverage of query (103 bits)
ABA4_BOTFU / Q14RS1 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
31% identity, 98% coverage of query (102 bits)
Q7XZH5 xanthoxin dehydrogenase (EC 1.1.1.288) from Oryza sativa (see paper)
36% identity, 84% coverage of query (102 bits)
HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
33% identity, 90% coverage of query (101 bits)
4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
35% identity, 95% coverage of query (101 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
30% identity, 97% coverage of query (101 bits)
5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
38% identity, 97% coverage of query (100 bits)
BDH1_SALOF / A0A8F5SIS3 (+)-borneol dehydrogenase 1; SoBDH1; EC 1.1.1.198 from Salvia officinalis (Sage) (see paper)
37% identity, 75% coverage of query (99.8 bits)
6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
32% identity, 89% coverage of query (99.8 bits)
4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
30% identity, 97% coverage of query (99.4 bits)
lvr / Q9LBG2 levodione reductase monomer from Leifsonia aquatica (see 3 papers)
lvr / BAA95121.1 levodione reductase from Leifsonia aquatica (see paper)
34% identity, 97% coverage of query (99.4 bits)
Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
34% identity, 97% coverage of query (99.4 bits)
1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
34% identity, 97% coverage of query (99.0 bits)
CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
30% identity, 97% coverage of query (99.0 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
30% identity, 98% coverage of query (98.6 bits)
5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
34% identity, 81% coverage of query (98.6 bits)
fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
31% identity, 96% coverage of query (98.2 bits)
SDR3A_ARATH / O80713 Short-chain dehydrogenase reductase 3a; AtSDR3a; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
37% identity, 75% coverage of query (98.2 bits)
3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
34% identity, 96% coverage of query (98.2 bits)
tsaC / P94681 4-sulfobenzyl alcohol dehydrogenase subunit (EC 1.1.1.257) from Comamonas testosteroni (see paper)
TSAC_COMTE / P94681 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2; Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; EC 1.2.1.62 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
35% identity, 87% coverage of query (97.8 bits)
A0JC04 octanol dehydrogenase (EC 1.1.1.73) from Ogataea wickerhamii (see paper)
32% identity, 96% coverage of query (96.7 bits)
6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
32% identity, 99% coverage of query (96.7 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
32% identity, 99% coverage of query (96.3 bits)
A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) from Arthrobacter sp. TS-15 (see paper)
31% identity, 99% coverage of query (95.9 bits)
baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
30% identity, 98% coverage of query (95.9 bits)
cpnA / Q8GAV9 cyclopentanol dehydrogenase (EC 1.1.1.163) from Comamonas sp. (strain NCIMB 9872) (see 2 papers)
CPNA_COMS9 / Q8GAV9 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas sp. (strain NCIMB 9872) (see paper)
CPNA_COMTE / Q937L4 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
cpmB / CAD10799.1 cyclohexanol dehydrogenase from Comamonas testosteroni (see paper)
30% identity, 97% coverage of query (95.9 bits)
1hdcA / P19992 Mechanism of inhibition of 3alpha,20beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor (see paper)
40% identity, 77% coverage of query (95.9 bits)
1gegE / Q48436 Cryatal structure analysis of meso-2,3-butanediol dehydrogenase (see paper)
33% identity, 95% coverage of query (95.9 bits)
2hsdA The refined three-dimensional structure of 3alpha,20beta- hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
40% identity, 77% coverage of query (95.9 bits)
budC / Q48436 acetoin reductase subunit (EC 1.1.1.304) from Klebsiella pneumoniae (see 4 papers)
BUDC_KLEPN / Q48436 Diacetyl reductase [(S)-acetoin forming]; Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase; EC 1.1.1.304 from Klebsiella pneumoniae (see paper)
Q48436 diacetyl reductase [(S)-acetoin forming] (EC 1.1.1.304); (S,S)-butanediol dehydrogenase (EC 1.1.1.76) from Klebsiella pneumoniae (see 2 papers)
budC / GB|AAC78679.1 diacetyl reductase ((S)-acetoin forming); EC 1.1.1.304 from Klebsiella pneumoniae (see 3 papers)
33% identity, 95% coverage of query (95.5 bits)
PRF|1611236A 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Streptomyces exfoliatus (see paper)
40% identity, 77% coverage of query (95.5 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
31% identity, 99% coverage of query (95.5 bits)
TPRL2_ERYCB / H9BFQ1 Tropinone reductase-like 2; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
32% identity, 99% coverage of query (95.1 bits)
gutD / CAA05517.1 glucitol-6-phosphate dehydrogenase from Clostridium beijerinckii (see paper)
34% identity, 76% coverage of query (95.1 bits)
TPRL1_ERYCB / H9BFQ0 Tropinone reductase-like 1; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
34% identity, 75% coverage of query (94.4 bits)
4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
33% identity, 96% coverage of query (94.4 bits)
Q7FAE2 momilactone-A synthase (EC 1.1.1.295) from Oryza sativa (see paper)
39% identity, 78% coverage of query (93.6 bits)
A0A0G2SJM3 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Fimbriaphyllia ancora (see paper)
30% identity, 80% coverage of query (93.6 bits)
DHB8_RAT / Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Rattus norvegicus (Rat) (see paper)
32% identity, 90% coverage of query (93.6 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
32% identity, 99% coverage of query (93.6 bits)
W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
32% identity, 78% coverage of query (93.2 bits)
Q58LW6 D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287) from Gluconobacter oxydans (see paper)
33% identity, 94% coverage of query (93.2 bits)
8y83A / A0A562MSV3 Crystal structure of a ketoreductase from sphingobacterium siyangense sy1 with co-enzyme
32% identity, 97% coverage of query (93.2 bits)
7qujA Structure of nsneps2, a 7s-cis-trans nepetalactone synthase (see paper)
32% identity, 85% coverage of query (92.8 bits)
W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
31% identity, 78% coverage of query (92.8 bits)
SDR / F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see paper)
ZERSY_ZINZE / F1SWA0 Zerumbone synthase; EC 1.1.1.326 from Zingiber zerumbet (Shampoo ginger) (Amomum zerumbet) (see paper)
F1SWA0 zerumbone synthase (EC 1.1.1.326) from Zingiber zerumbet (see 2 papers)
32% identity, 83% coverage of query (92.0 bits)
OsMAS / Q7FAE1 momilactone A synthase (EC 1.1.1.295) from Oryza sativa subsp. japonica (see 2 papers)
MOMAS_ORYSJ / Q7FAE1 Momilactone A synthase; OsMAS; EC 1.1.1.295 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q7FAE1 momilactone-A synthase (EC 1.1.1.295) from Oryza sativa (see 2 papers)
39% identity, 78% coverage of query (92.0 bits)
5ts3A / C0RKU3 Crystal structure of a 3-oxoacyl-[acyl-carrier protein] reductase with bound NAD from brucella melitensis
33% identity, 96% coverage of query (92.0 bits)
Q93Y47 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51) from Digitalis lanata (see 2 papers)
3bhsd / CAC93667.1 3-beta-hydroxysteroiddehydrogenase from Digitalis lanata (see paper)
37% identity, 77% coverage of query (91.7 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
31% identity, 99% coverage of query (91.7 bits)
SRDC_NEUCR / Q7SHI4 Short-chain dehydrogenase srdC; Sordarial biosynthesis cluster protein srdC; EC 1.1.1.- from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 3 papers)
35% identity, 87% coverage of query (91.7 bits)
W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
31% identity, 78% coverage of query (91.3 bits)
chnA / Q9F7E0 cyclohexanol dehydrogenase (EC 1.1.1.245) from Acinetobacter sp. (strain SE19) (see 4 papers)
CHNA_ACISS / Q9F7E0 Cyclohexanol dehydrogenase; EC 1.1.1.245 from Acinetobacter sp. (strain SE19) (see paper)
33% identity, 97% coverage of query (91.3 bits)
8jfgA Crystal structure of 3-oxoacyl-acp reductase fabg in complex with NADP+ and 3-keto-octanoyl-acp from helicobacter pylori (see paper)
31% identity, 99% coverage of query (90.9 bits)
6f9qC / A0A3Q8GLE8 Binary complex of a 7s-cis-cis-nepetalactol cyclase from nepeta mussinii with NAD+ (see paper)
33% identity, 86% coverage of query (90.9 bits)
NEPS3_NEPRA / A0A3Q8GLE8 (+)-cis,cis-nepetalactol synthase NEPS3; Nepetalactol-related short-chain reductase 3; NmNEPS3; EC 5.5.1.35 from Nepeta racemosa (Catmint) (Raceme catnip) (see 2 papers)
33% identity, 86% coverage of query (90.9 bits)
ISPD_MENPI / Q5C9I9 (-)-isopiperitenol/(-)-carveol dehydrogenase, mitochondrial; EC 1.1.1.223; EC 1.1.1.243 from Mentha piperita (Peppermint) (Mentha aquatica x Mentha spicata) (see 2 papers)
35% identity, 77% coverage of query (90.9 bits)
4iinA Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from helicobacter pylori 26695 complexed with NAD+
30% identity, 99% coverage of query (90.9 bits)
Build an alignment for WP_004321104.1 and 93 homologs with ≥ 30% identity
Or download the sequences
baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
29% identity, 98% coverage of query (90.9 bits)
4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
29% identity, 98% coverage of query (90.5 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
31% identity, 96% coverage of query (90.5 bits)
BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
32% identity, 97% coverage of query (90.5 bits)
budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
30% identity, 97% coverage of query (90.1 bits)
3rwbA Crystal structure of complex of 4pal (4-pyridoxolactone) and pldh (tetrameric pyridoxal 4-dehydrogenase) from mesorhizobium loti
30% identity, 96% coverage of query (90.1 bits)
3ndrA / Q988B7 Crystal structure of tetrameric pyridoxal 4-dehydrogenase from mesorhizobium loti
30% identity, 96% coverage of query (90.1 bits)
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Lawrence Berkeley National Laboratory