Searching for up to 100 curated homologs for WP_005346465.1 NCBI__GCF_000173975.1:WP_005346465.1 (418 a.a.)
Found high-coverage hits (≥70%) to 16 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
A7Y114 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Halobacillus halophilus (see paper)
46% identity, 98% coverage of query (357 bits)
ProA / b0243 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
proA / P07004 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli (strain K12) (see 27 papers)
PROA_ECOLI / P07004 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; EC 1.2.1.41 from Escherichia coli (strain K12) (see 3 papers)
46% identity, 94% coverage of query (353 bits)
PROA_YEAST / P54885 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; GSA dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; EC 1.2.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
38% identity, 100% coverage of query (278 bits)
P5CS1 / P54887 δ1-pyrroline-5-carboxylate synthetase (EC 1.2.1.41; EC 2.7.2.11) from Arabidopsis thaliana (see 4 papers)
38% identity, 99% coverage of query (278 bits)
P5CS1_ORYSJ / O04226 Delta-1-pyrroline-5-carboxylate synthase 1; OsP5CS1; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice) (see paper)
37% identity, 100% coverage of query (271 bits)
ALDH18A1 / P54886 δ-1-pyrroline-5-carboxylate synthase (EC 1.2.1.41; EC 2.7.2.11) from Homo sapiens (see 4 papers)
P5CS_HUMAN / P54886 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Homo sapiens (Human) (see 8 papers)
36% identity, 95% coverage of query (266 bits)
P5CS_MOUSE / Q9Z110 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Mus musculus (Mouse) (see paper)
Q9Z110 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Mus musculus (see paper)
36% identity, 95% coverage of query (266 bits)
p5cs / CAB40834.1 pyrroline-5-carboxylate synthetase from Vitis vinifera (see paper)
38% identity, 99% coverage of query (261 bits)
P5CS2_ORYSJ / Q941T1 Delta-1-pyrroline-5-carboxylate synthase 2; OsP5CS2; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
Q941T1 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Oryza sativa (see paper)
36% identity, 100% coverage of query (257 bits)
Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) from Echinicola vietnamensis KMM 6221, DSM 17526
39% identity, 95% coverage of query (256 bits)
7wxgA / Q9VNW6 Gpr domain closed form of drosophila p5cs filament with glutamate, atp, and NADPH (see paper)
33% identity, 97% coverage of query (229 bits)
7wxiA Gpr domain of drosophila p5cs filament with glutamate and atpgammas
33% identity, 97% coverage of query (229 bits)
4jbeB / C7MW73 1.95 angstrom crystal structure of gamma-glutamyl phosphate reductase from saccharomonospora viridis.
31% identity, 96% coverage of query (150 bits)
Build an alignment for WP_005346465.1 and 13 homologs with ≥ 30% identity
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5j7iB Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp (see paper)
26% identity, 78% coverage of query (81.6 bits)
5j7iC Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp
26% identity, 78% coverage of query (81.6 bits)
SAUS_BILW3 / E5Y8P9 Sulfoacetaldehyde dehydrogenase (acylating); NADPH-dependent acylating sulfoacetaldehyde dehydrogenase; Sulfoacetyl-CoA reductase; EC 1.2.1.81 from Bilophila wadsworthia (strain 3_1_6) (see paper)
25% identity, 74% coverage of query (65.1 bits)
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Lawrence Berkeley National Laboratory