Searching for up to 100 curated homologs for WP_005454243.1 NCBI__GCF_000244975.1:WP_005454243.1 (493 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

P9WFV9 glutamate-tRNA ligase (EC 6.1.1.17) from Mycobacterium tuberculosis (see paper)
    63% identity, 100% coverage of query (611 bits)

gltX / P22250 glutamyl-tRNA^Glx synthetase (EC 6.1.1.17; EC 6.1.1.24) from Bacillus subtilis (strain 168) (see 4 papers)
    40% identity, 98% coverage of query (360 bits)

4griB / O51345 Crystal structure of a glutamyl-tRNA synthetase glurs from borrelia burgdorferi bound to glutamic acid and zinc (see paper)
    35% identity, 98% coverage of query (322 bits)

Q9X2I8 glutamate-tRNAGln ligase (EC 6.1.1.24) from Thermotoga maritima (see paper)
    37% identity, 98% coverage of query (313 bits)

3al0C / Q9WY94,Q9X2I8 Crystal structure of the glutamine transamidosome from thermotoga maritima in the glutamylation state. (see paper)
    37% identity, 98% coverage of query (313 bits)

SYEM_ARATH / Q9FEA2 Glutamate--tRNA ligase, chloroplastic/mitochondrial; AtERS; Glutamyl-tRNA synthetase; GluRS; Protein OVULE ABORTION 3; EC 6.1.1.17 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    37% identity, 97% coverage of query (309 bits)

Q9XCL6 glutamate-tRNA ligase (EC 6.1.1.17) from Pseudomonas aeruginosa (see paper)
    38% identity, 98% coverage of query (301 bits)

SYE_THET8 / P27000 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
2cuzA / P27000 Glutamyl-tRNA synthetase from thermus thermophilus in complex with l- glutamate (see paper)
    39% identity, 98% coverage of query (297 bits)

2cv2A Glutamyl-tRNA synthetase from thermus thermophilus in complex with tRNA(glu) and an enzyme inhibitor, glu-ams
    39% identity, 98% coverage of query (297 bits)

2cv1A Glutamyl-tRNA synthetase from thermus thermophilus in complex with tRNA(glu), atp, and an analog of l-glutamate: a quaternary complex
    39% identity, 98% coverage of query (297 bits)

1n78A Crystal structure of thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(glu) and glutamol-amp.
    39% identity, 98% coverage of query (297 bits)

1j09A Crystal structure of thermus thermophilus glutamyl-tRNA synthetase complexed with atp and glu
    39% identity, 98% coverage of query (297 bits)

1g59A Glutamyl-tRNA synthetase complexed with tRNA(glu).
    38% identity, 98% coverage of query (291 bits)

8vc5A / Q9XCL6 Crystal structure of glutamyl-tRNA synthetase glurs from pseudomonas aeruginosa (zinc bound)
    37% identity, 98% coverage of query (290 bits)

6brlA / A0A1T3HI54 Crystal structure of a glutamate tRNA ligase from elizabethkingia meningosepticum ccug26117 in complex with its amino acid (see paper)
    33% identity, 98% coverage of query (277 bits)

SYE_THEVB / Q8DLI5 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) (see paper)
    36% identity, 96% coverage of query (267 bits)

2cfoA / Q8DLI5 Non-discriminating glutamyl-tRNA synthetase from thermosynechococcus elongatus in complex with glu (see paper)
    36% identity, 96% coverage of query (267 bits)

8i9iA / P04805 Glutamyl-tRNA synthetase from escherichia coli bound to glutamate and zinc
    34% identity, 98% coverage of query (261 bits)

GltM / b2400 glutamate—tRNA ligase (EC 6.1.1.17) from Escherichia coli K-12 substr. MG1655 (see 39 papers)
gltX / P04805 glutamate—tRNA ligase (EC 6.1.1.17) from Escherichia coli (strain K12) (see 39 papers)
SYE_ECOLI / P04805 Glutamate--tRNA ligase; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Escherichia coli (strain K12) (see 9 papers)
gltX / GB|AAC75457.1 glutamyl-tRNA synthetase; EC 6.1.1.17 from Escherichia coli K12 (see 10 papers)
    34% identity, 98% coverage of query (261 bits)

Q8IDD3 glutamate-tRNAGln ligase (EC 6.1.1.24) from Plasmodium falciparum (see paper)
    34% identity, 71% coverage of query (235 bits)

SYEM_HUMAN / Q5JPH6 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial; Glutamate--tRNA(Gln) ligase EARS2, mitochondrial; Glutamyl-tRNA synthetase; GluRS; Mitochondrial glutamyl-tRNA synthetase; mtGluRS; EC 6.1.1.24; EC 6.1.1.17 from Homo sapiens (Human) (see 4 papers)
    33% identity, 96% coverage of query (219 bits)

SYEM_SCHPO / Q9HDX9 Glutamate--tRNA ligase, mitochondrial; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    30% identity, 97% coverage of query (219 bits)

4g6zA / Q2SX36 Crystal structure of a glutamyl-tRNA synthetase glurs from burkholderia thailandensis bound to l-glutamate (see paper)
    37% identity, 71% coverage of query (213 bits)

CCNA_01982 glutamyl-tRNA(Glx) synthetase (EC 6.1.1.24) from Caulobacter crescentus NA1000
    34% identity, 98% coverage of query (207 bits)

SYEM_YEAST / P48525 Glutamate--tRNA ligase, mitochondrial; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 98% coverage of query (201 bits)

Build an alignment

Build an alignment for WP_005454243.1 and 25 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

A7AS98 glutamate-tRNA ligase (EC 6.1.1.17) from Babesia bovis (see paper)
    26% identity, 95% coverage of query (145 bits)

SYQ_HUMAN / P47897 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Homo sapiens (Human) (see 6 papers)
P47897 glutamine-tRNA ligase (EC 6.1.1.18) from Homo sapiens (see 4 papers)
    23% identity, 74% coverage of query (58.9 bits)

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