Sites on a Tree

 

Searching for up to 100 curated homologs for WP_005455986.1 NCBI__GCF_000244975.1:WP_005455986.1 (440 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

C9K2Z6 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Streptomyces mobaraensis (see paper)
    60% identity, 97% coverage of query (503 bits)

Build an alignment

Build an alignment for WP_005455986.1 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

P20D1_MOUSE / Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see 6 papers)
    27% identity, 99% coverage of query (128 bits)

P20D1_HUMAN / Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; EC 3.5.1.114; EC 3.5.1.14 from Homo sapiens (Human) (see 2 papers)
    28% identity, 95% coverage of query (123 bits)

P37111 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Sus scrofa (see 6 papers)
    26% identity, 94% coverage of query (103 bits)

P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig)
    26% identity, 94% coverage of query (103 bits)

ACY1 / Q03154 aminoacylase 1 monomer (EC 3.5.1.14) from Homo sapiens (see 7 papers)
ACY1_HUMAN / Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 5 papers)
Q03154 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Homo sapiens (see 4 papers)
    26% identity, 94% coverage of query (94.7 bits)

ACY1_MOUSE / Q99JW2 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Mus musculus (Mouse) (see 2 papers)
Q99JW2 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Mus musculus (see 2 papers)
    26% identity, 96% coverage of query (94.7 bits)

Q6AYS7 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Rattus norvegicus (see 2 papers)
    25% identity, 94% coverage of query (93.6 bits)

G8EJ34 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Helicoverpa armigera (see paper)
    24% identity, 82% coverage of query (89.7 bits)

A0A219YQV4 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Helicoverpa assulta (see paper)
    24% identity, 82% coverage of query (88.2 bits)

G8EJ32 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Heliothis virescens (see paper)
    22% identity, 84% coverage of query (86.3 bits)

ACY1B_RAT / Q6PTT0 Aminoacylase-1B; ACY-1B; ACY IB; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Rattus norvegicus (Rat) (see paper)
    25% identity, 94% coverage of query (85.5 bits)

CPS1 / P27614 carboxypeptidase S (EC 3.4.17.4) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 7 papers)
CBPS_YEAST / P27614 Carboxypeptidase S; GLY-X carboxypeptidase; YSCS; EC 3.4.17.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    25% identity, 79% coverage of query (77.4 bits)

2pokA / A0A0H2UN21 Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
    26% identity, 72% coverage of query (68.6 bits)

Q92Y75 acetylornithine deacetylase (EC 3.5.1.16) from Sinorhizobium meliloti (see paper)
    29% identity, 82% coverage of query (68.6 bits)

5vo3A / P44514 Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
    23% identity, 97% coverage of query (65.5 bits)

dapE / P44514 N-succinyl-L,L-diaminopimelate desuccinylase subunit (EC 3.5.1.18) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
DAPE_HAEIN / P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 7 papers)
P44514 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Haemophilus influenzae (see 3 papers)
    23% identity, 97% coverage of query (65.5 bits)

dapE / CAA08876.1 DapE from Bordetella pertussis (see paper)
    21% identity, 93% coverage of query (60.5 bits)

7t1qA / A3M8H2 Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
    25% identity, 93% coverage of query (59.7 bits)

CA265_RS18500 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Pedobacter sp. GW460-11-11-14-LB5
    22% identity, 76% coverage of query (54.7 bits)

Echvi_3851 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
    23% identity, 77% coverage of query (50.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory