Searching for up to 100 curated homologs for WP_005459144.1 NCBI__GCF_000244975.1:WP_005459144.1 (457 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Y1077_MYCTU / P9WP51 Probable cystathionine beta-synthase Rv1077; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    72% identity, 99% coverage of query (655 bits)

7xnzB / P9WP51 Native cystathionine beta-synthase of mycobacterium tuberculosis. (see paper)
    73% identity, 99% coverage of query (655 bits)

7xoyA Cystathionine beta-synthase of mycobacterium tuberculosis in the presence of s-adenosylmethionine and serine.
    73% identity, 99% coverage of query (655 bits)

Q9EYM7 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Streptomyces venezuelae (see paper)
    71% identity, 99% coverage of query (642 bits)

7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
    39% identity, 98% coverage of query (298 bits)

Cbs / P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus (see 2 papers)
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat) (see 3 papers)
    41% identity, 93% coverage of query (297 bits)

4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
    40% identity, 97% coverage of query (297 bits)

8s5hA / P35520 Full-length human cystathionine beta-synthase with c-terminal 6xhis- tag, basal state, helical reconstruction (see paper)
    39% identity, 98% coverage of query (295 bits)

uptG / AAK53485.1 cystathionine beta-lyase from Xanthomonas campestris pv. campestris (see 4 papers)
    39% identity, 98% coverage of query (295 bits)

CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
    39% identity, 98% coverage of query (293 bits)

CBS / A0A563XPB1 cystathionine β-synthase (EC 4.2.1.22) from Gallus gallus (see 7 papers)
    40% identity, 95% coverage of query (283 bits)

CYS4 / P32582 Cys4 (EC 4.2.1.22) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
CBS_YEAST / P32582 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; Sulfur transfer protein 4; EC 4.2.1.22 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32582 cystathionine beta-synthase (EC 4.2.1.22) from Saccharomyces cerevisiae (see 3 papers)
    35% identity, 99% coverage of query (278 bits)

5ohxA / Q2V0C9 Structure of active cystathionine b-synthase from apis mellifera (see paper)
    38% identity, 100% coverage of query (278 bits)

CBS_APIME / Q2V0C9 Cystathionine beta-synthase; EC 4.2.1.22 from Apis mellifera (Honeybee) (see paper)
Q2V0C9 cystathionine beta-synthase (EC 4.2.1.22) from Apis mellifera (see paper)
    38% identity, 100% coverage of query (277 bits)

mecA cystathionine beta-synthase; EC 4.2.1.22 from Emericella nidulans (see 2 papers)
    39% identity, 87% coverage of query (266 bits)

3pc3A / Q9VRD9 Full length structure of cystathionine beta-synthase from drosophila in complex with aminoacrylate (see paper)
    38% identity, 98% coverage of query (264 bits)

3pc2A Full length structure of cystathionine beta-synthase from drosophila
    38% identity, 98% coverage of query (264 bits)

3pc4A Full length structure of cystathionine beta-synthase from drosophila in complex with serine
    38% identity, 98% coverage of query (264 bits)

Q9VRD9 cystathionine beta-synthase (EC 4.2.1.22) from Drosophila melanogaster (see paper)
    38% identity, 98% coverage of query (263 bits)

6xwlC / A0A125YSJ9 Cystathionine beta-synthase from toxoplasma gondii (see paper)
    37% identity, 98% coverage of query (255 bits)

6xylA Crystal structure of delta466-491 cystathionine beta-synthase from toxoplasma gondii with l-serine
    37% identity, 98% coverage of query (246 bits)

CYSK1_CAEEL / Q93244 Cysteine synthase 1; O-acetylserine (thiol)-lyase 1; OAS-TL; EC 2.5.1.47 from Caenorhabditis elegans (see 3 papers)
Q93244 cysteine synthase (EC 2.5.1.47) from Caenorhabditis elegans (see 2 papers)
    42% identity, 71% coverage of query (221 bits)

O81155 cysteine synthase (EC 2.5.1.47) from Solanum tuberosum (see paper)
    41% identity, 70% coverage of query (216 bits)

OASC / Q43725 O-acetylserine (thiol) lyase (EC 2.5.1.47) from Arabidopsis thaliana (see 3 papers)
CYSKM_ARATH / Q43725 Cysteine synthase, mitochondrial; Beta-substituted Ala synthase 2;2; ARAth-Bsas2;2; CSase C; AtCS-C; CS-C; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL C; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q43725 cysteine synthase (EC 2.5.1.47) from Arabidopsis thaliana (see 2 papers)
    39% identity, 70% coverage of query (206 bits)

OASB / P47999 O-acetylserine (thiol) lyase (EC 2.5.1.47) from Arabidopsis thaliana (see 3 papers)
CYSKP_ARATH / P47999 Cysteine synthase, chloroplastic/chromoplastic; At.OAS.7-4; Beta-substituted Ala synthase 2;1; ARAth-Bsas2;1; CSase B; AtCS-B; CS-B; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL B; cpACS1; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P47999 cysteine synthase (EC 2.5.1.47) from Arabidopsis thaliana (see 2 papers)
    38% identity, 70% coverage of query (200 bits)

CAS2_SOLTU / Q9FS29 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 2, mitochondrial; EC 2.5.1.47; EC 4.4.1.9 from Solanum tuberosum (Potato) (see paper)
Q9FS29 L-3-cyanoalanine synthase (EC 4.4.1.9) from Solanum tuberosum (see paper)
    35% identity, 70% coverage of query (171 bits)

5z5cB / Q8REP3 Crystal structure of hydrogen sulfide-producing enzyme (fn1055) from fusobacterium nucleatum: lysine-dimethylated form (see paper)
    31% identity, 72% coverage of query (140 bits)

5b55A Crystal structure of hydrogen sulfide-producing enzyme (fn1055) d232n mutant in complexed with alpha-aminoacrylate intermediate: lysine- dimethylated form
    31% identity, 72% coverage of query (140 bits)

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Build an alignment for WP_005459144.1 and 28 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

CBS1_CAEEL / G5EFH8 Cystathionine beta-synthase cbs-1; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Caenorhabditis elegans (see 2 papers)
    28% identity, 72% coverage of query (94.0 bits)

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