Sites on a Tree

 

Searching for up to 100 curated homologs for WP_006748504.1 NCBI__GCF_000227685.2:WP_006748504.1 (375 a.a.)

Found high-coverage hits (≥70%) to 13 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AroC / b2329 chorismate synthase (EC 4.2.3.5) from Escherichia coli K-12 substr. MG1655 (see 32 papers)
aroC / P12008 chorismate synthase (EC 4.2.3.5) from Escherichia coli (strain K12) (see 32 papers)
AROC_ECOLI / P12008 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EPSP phospholyase; EC 4.2.3.5 from Escherichia coli (strain K12) (see 8 papers)
    73% identity, 96% coverage of query (529 bits)

B5AAU3 chorismate synthase (EC 4.2.3.5) from Hordeum vulgare (see paper)
    49% identity, 93% coverage of query (334 bits)

AROC_HELPY / P56122 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
1um0A / P56122 Crystal structure of chorismate synthase complexed with fmn (see paper)
    45% identity, 91% coverage of query (299 bits)

AROC_YEAST / P28777 Chorismate synthase ARO2; 5-enolpyruvylshikimate-3-phosphate phospholyase; Aromatic amino acid requiring protein 2; EC 1.5.1.38; EC 4.2.3.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
ARO2 / CAA42745.1 chorismate synthase from Saccharomyces cerevisiae (see paper)
    46% identity, 93% coverage of query (293 bits)

C8Z2I6 chorismate synthase (EC 4.2.3.5) from Verticillium longisporum (see paper)
    43% identity, 93% coverage of query (280 bits)

AROC_NEUCR / Q12640 Chorismate synthase aro-2; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 1.5.1.38; EC 4.2.3.5 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 12 papers)
    43% identity, 93% coverage of query (275 bits)

2qhfA / P9WPY1 Mycobacterium tuberculosis chorismate synthase in complex with nca
    39% identity, 88% coverage of query (191 bits)

AROC_MYCTU / P9WPY1 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    39% identity, 88% coverage of query (191 bits)

AROC_AQUAE / O66493 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Aquifex aeolicus (strain VF5) (see paper)
    37% identity, 88% coverage of query (188 bits)

2o12A Mycobacterium tuberculosis chorismate synthase in complex with fmn
    39% identity, 88% coverage of query (187 bits)

Q71Y87 chorismate synthase (EC 4.2.3.5) from Listeria monocytogenes (see paper)
    35% identity, 82% coverage of query (158 bits)

AROC_STAAU / Q59803 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Staphylococcus aureus (see paper)
    32% identity, 90% coverage of query (153 bits)

AROC_STRPN / P0A2Y6 Chorismate synthase; CS; 5-enolpyruvylshikimate-3-phosphate phospholyase; EC 4.2.3.5 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see paper)
1qxoA / P0A2Y6 Crystal structure of chorismate synthase complexed with oxidized fmn and epsp (see paper)
    36% identity, 88% coverage of query (146 bits)

Build an alignment

Build an alignment for WP_006748504.1 and 13 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory