Searching for up to 100 curated homologs for WP_008625476.1 NCBI__GCF_000330725.2:WP_008625476.1 (484 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
    44% identity, 99% coverage of query (383 bits)

P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
    44% identity, 99% coverage of query (383 bits)

IDH2 / P28241 isocitrate dehydrogenase [NAD] β subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH2_YEAST / P28241 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P28241 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
    44% identity, 70% coverage of query (272 bits)

3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
    44% identity, 70% coverage of query (264 bits)

IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    42% identity, 70% coverage of query (256 bits)

Q9HLV8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermoplasma acidophilum (see paper)
    36% identity, 71% coverage of query (206 bits)

IDH3_ARATH / O81796 Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; IDH-III; Isocitric dehydrogenase 3; NAD(+)-specific ICDH 3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O81796 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    38% identity, 70% coverage of query (204 bits)

hdh / BAD06515.1 homoisocitrate dehydrogenase, partial from Deinococcus radiodurans (see paper)
    36% identity, 70% coverage of query (193 bits)

LYS12_SCHPO / O14104 Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.87 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    34% identity, 70% coverage of query (171 bits)

1tyoA / Q9YE81 Isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in complex with etheno-NADP (see paper)
    30% identity, 70% coverage of query (162 bits)

LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
    34% identity, 70% coverage of query (160 bits)

LEU32_ARATH / P93832 3-isopropylmalate dehydrogenase 2, chloroplastic; 3-IPM-DH 2; AtIMDH2; AtIMDH3; IMDH 2; Beta-IPM dehydrogenase 2; Isopropylmalate dehydrogenase 2; AtIMD2; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P93832 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
    32% identity, 71% coverage of query (159 bits)

LEU33_ARATH / Q9SA14 3-isopropylmalate dehydrogenase 3, chloroplastic; 3-IPM-DH 3; AtIMDH2; AtIMDH3; IMDH 3; Beta-IPM dehydrogenase 3; Isopropylmalate dehydrogenase 3; AtIMD3; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9SA14 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 3 papers)
    33% identity, 70% coverage of query (157 bits)

IMDH3 / Q9FMT1 isopropylmalate dehydrogenase 3 (EC 1.1.1.85) from Arabidopsis thaliana (see paper)
LEU31_ARATH / Q9FMT1 3-isopropylmalate dehydrogenase 1, chloroplastic; 3-IPM-DH 1; AtIMDH1; IMDH 1; Beta-IPM dehydrogenase 1; Isopropylmalate dehydrogenase 1; AtIMD1; Methylthioalkylmalate dehydrogenase 1; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9FMT1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
    33% identity, 72% coverage of query (155 bits)

LEU3_SALTY / P37412 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
P37412 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
1cnzA / P37412 3-isopropylmalate dehydrogenase (ipmdh) from salmonella typhimurium (see paper)
    34% identity, 70% coverage of query (153 bits)

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Build an alignment for WP_008625476.1 and 15 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

1xkdA Ternary complex of isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix
    29% identity, 70% coverage of query (152 bits)

1a05A / Q56268 Crystal structure of the complex of 3-isopropylmalate dehydrogenase from thiobacillus ferrooxidans with 3-isopropylmalate (see paper)
    31% identity, 70% coverage of query (147 bits)

LEU3_ACIFR / Q56268 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans) (see 2 papers)
Q56268 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Acidithiobacillus ferrooxidans (see paper)
    31% identity, 70% coverage of query (147 bits)

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