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Searching for up to 100 curated homologs for WP_009562658.1 NCBI__GCF_000021485.1:WP_009562658.1 (222 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PSPA_HYDTT / D3DFG8 Phosphoserine phosphatase 1; PSP 1; PSPase 1; Metal-independent phosphoserine phosphatase 1; iPSP1; O-phosphoserine phosphohydrolase 1; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFG8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see 3 papers)
    37% identity, 82% coverage of query (130 bits)

4ij6A / D3DFG8 Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
    36% identity, 82% coverage of query (126 bits)

PSPB_HYDTT / D3DFP8 Putative phosphoserine phosphatase 2; PSP 2; PSPase 2; Metal-independent phosphoserine phosphatase 2; iPSP2; O-phosphoserine phosphohydrolase 2; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFP8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see paper)
    34% identity, 81% coverage of query (112 bits)

cobC / D1BMI5 adenosylcobamide phosphatase (EC 3.1.3.73) from Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3) (see paper)
    36% identity, 77% coverage of query (112 bits)

1h2eA / Q9ALU0 Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
    37% identity, 83% coverage of query (97.8 bits)

1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate
    37% identity, 83% coverage of query (97.8 bits)

GPGP_MYCTU / P9WIC7 Glucosyl-3-phosphoglycerate phosphatase; Mannosyl-3-phosphoglycerate phosphatase; EC 3.1.3.85; EC 3.1.3.70 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WIC6 glucosyl-3-phosphoglycerate phosphatase (EC 3.1.3.85) from Mycobacterium tuberculosis (see paper)
P9WIC7 glucosyl-3-phosphoglycerate phosphatase (EC 3.1.3.85) from Mycobacterium tuberculosis (see paper)
    36% identity, 82% coverage of query (91.3 bits)

4pzaB / P9WIC6 The complex structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c with inorganic phosphate (see paper)
    36% identity, 82% coverage of query (90.9 bits)

4qihA The structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c complexes with vo3
    36% identity, 81% coverage of query (90.1 bits)

PHOE_BACSU / O07617 Uncharacterized phosphatase PhoE; EC 3.1.3.- from Bacillus subtilis (strain 168) (see 2 papers)
    33% identity, 86% coverage of query (89.4 bits)

PMGY_SCHPO / P36623 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
gpm1 / RF|NP_594889.1 monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1; EC 5.4.2.1 from Schizosaccharomyces pombe (see paper)
    30% identity, 84% coverage of query (85.1 bits)

Q2YJN6 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Brucella abortus (see paper)
    34% identity, 72% coverage of query (84.7 bits)

YtjC / b4395 putative phosphatase from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gpmB / RF|NP_418812 PGAM from Escherichia coli K12 (see paper)
    34% identity, 87% coverage of query (84.7 bits)

6m1xC Crystal structure of phosphoserine phosphatase in complex with 3- phosphoglyceric acid from entamoeba histolytica
    30% identity, 83% coverage of query (81.6 bits)

5zr2C / N9V397 Crystal structure of phosphoserine phosphatase mutant (h9a) from entamoeba histolytica in complex with phosphoserine (see paper)
    30% identity, 83% coverage of query (77.8 bits)

cobC / P39701 adenosylcobalamin/α-ribazole phosphatase (EC 3.1.3.73) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
COBC_SALTY / P39701 Adenosylcobalamin/alpha-ribazole phosphatase; Adenosylcobalamin phosphatase; Alpha-ribazole-5'-phosphate phosphatase; EC 3.1.3.73 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
P39701 adenosylcobalamin/alpha-ribazole phosphatase (EC 3.1.3.73) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
cobC / RF|NP_459635.1 alpha-ribazole phosphatase; EC 3.1.3.73 from Salmonella typhimurium LT2 (see 2 papers)
    30% identity, 80% coverage of query (74.7 bits)

Build an alignment

Build an alignment for WP_009562658.1 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PhpB / b0638 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
cobC / P52086 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli (strain K12) (see 2 papers)
    29% identity, 80% coverage of query (72.8 bits)

GPM_THEAC / Q9HIJ2 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) (see paper)
    30% identity, 84% coverage of query (72.4 bits)

SERCL_ARATH / F4KI56 Metal-independent phosphoserine phosphatase; iPSP; Phosphoglycerate mutase-like protein 3; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    32% identity, 83% coverage of query (72.0 bits)

SUGPH_MYCTU / Q6MWZ7 Acid phosphatase; Broad-specificity phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.2; EC 3.1.3.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    31% identity, 82% coverage of query (66.6 bits)

F26_ARATH / Q9MB58 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; 6PF-2-K/Fru-2,6-P2ase; AtF2KP; PFK/FBPase; EC 2.7.1.105; EC 3.1.3.46 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9MB58 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Arabidopsis thaliana (see 3 papers)
    27% identity, 85% coverage of query (58.9 bits)

PFKFB3 / Q16875 Fructose-2,6-bisphosphatase (EC 2.7.1.105; EC 3.1.3.46) from Homo sapiens (see 9 papers)
F263_HUMAN / Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 5 papers)
Q16875 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 21 papers)
    27% identity, 96% coverage of query (48.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory