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Searching for up to 100 curated homologs for WP_010442632.1 NCBI__GCF_000192475.1:WP_010442632.1 (492 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TGNC_ACIAD / Q6F9F7 (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone dehydrogenase; MFMB dehydrogenase; EC 1.2.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    53% identity, 99% coverage of query (545 bits)

pnpD / C6FI42 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas putida (see paper)
    42% identity, 96% coverage of query (391 bits)

5gtkA NAD+ complex structure of aldehyde dehydrogenase from bacillus cereus
    41% identity, 96% coverage of query (387 bits)

5gtlA NADPH complex structure of aldehyde dehydrogenase from bacillus cereus
    41% identity, 96% coverage of query (387 bits)

4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
    41% identity, 96% coverage of query (384 bits)

ALDH4_BACSU / O34660 Putative aldehyde dehydrogenase DhaS; EC 1.2.1.3 from Bacillus subtilis (strain 168) (see paper)
    40% identity, 97% coverage of query (374 bits)

pdcG / D2STN3 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas sp. 1-7 (see paper)
    40% identity, 98% coverage of query (373 bits)

pnpE / C1I208 maleylacetate reductase (EC 1.3.1.32) from Pseudomonas sp. (strain WBC-3) (see paper)
C1I208 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas sp. WBC-3 (see paper)
    40% identity, 99% coverage of query (372 bits)

4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
    40% identity, 98% coverage of query (372 bits)

4pxlA / Q8S532 Structure of zm aldh2-3 (rf2c) in complex with NAD (see paper)
    42% identity, 95% coverage of query (366 bits)

LADH / A3LNE3 NAD(P)+ L-lactaldehyde dehydrogenase from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (see paper)
    40% identity, 96% coverage of query (363 bits)

ALDH1_ARTAN / C5I9X1 Aldehyde dehydrogenase 1; Artemisinic aldehyde oxidase; Artemisinate synthase; Dihydroartemisinic aldehyde oxidase; EC 1.2.1.- from Artemisia annua (Sweet wormwood) (see 3 papers)
    41% identity, 95% coverage of query (362 bits)

ALDH_DAVTA / P40108 Aldehyde dehydrogenase; ALDDH; ALDH; Allergen Cla h 3; Allergen Cla h III; Allergen Cla h 10; EC 1.2.1.3 from Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) (see paper)
    41% identity, 97% coverage of query (362 bits)

F8TW85 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Sphingomonas sp. (see paper)
    40% identity, 99% coverage of query (357 bits)

AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    40% identity, 95% coverage of query (355 bits)

O14293 Putative aldehyde dehydrogenase-like protein C9E9.09c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    40% identity, 96% coverage of query (349 bits)

ALDH1 / A0A2I7G3B0 trans-chrysanthemal dehydrogenase from Tanacetum cinerariifolium (see paper)
ALDH1_TANCI / A0A2I7G3B0 Aldehyde dehydrogenase 1; TcALDH1; Trans-chrysanthemic acid synthase; EC 1.2.1.5; EC 1.2.1.- from Tanacetum cinerariifolium (Dalmatian daisy) (Chrysanthemum cinerariifolium) (see paper)
    40% identity, 95% coverage of query (347 bits)

ALD5 / P40047 aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
ALDH5_YEAST / P40047 Aldehyde dehydrogenase 5, mitochondrial; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    40% identity, 96% coverage of query (347 bits)

peaE / B1N7H3 phenylacetaldehyde dehydrogenase monomer (EC 1.2.1.39) from Pseudomonas putida (see paper)
B1N7H3 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Pseudomonas putida (see paper)
    39% identity, 96% coverage of query (345 bits)

6wsbA / Q3JLL8 Crystal structure of a betaine aldehyde dehydrogenase from burkholderia pseudomallei bound to cofactor NAD (see paper)
    41% identity, 96% coverage of query (345 bits)

Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
    36% identity, 96% coverage of query (345 bits)

4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
    36% identity, 96% coverage of query (344 bits)

Q9LRE9 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
    39% identity, 95% coverage of query (344 bits)

Q9FRX7 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
    40% identity, 98% coverage of query (343 bits)

BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
    38% identity, 98% coverage of query (343 bits)

4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
    38% identity, 97% coverage of query (343 bits)

ALD4 / P46367 potassium-activated aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ALDH4_YEAST / P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial; K(+)-activated acetaldehyde dehydrogenase; K(+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P46367 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Saccharomyces cerevisiae (see paper)
    38% identity, 95% coverage of query (343 bits)

2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
    38% identity, 97% coverage of query (343 bits)

2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
    38% identity, 97% coverage of query (343 bits)

8rwkA / P46367 Cryoem structure of the central ald4 filament determined by filamentid (see paper)
    38% identity, 95% coverage of query (342 bits)

AL2B7_ARATH / Q8S528 Aldehyde dehydrogenase family 2 member B7, mitochondrial; ALDH2b; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    39% identity, 95% coverage of query (342 bits)

aldA / RF|XP_658158.1 aldehyde dehydrogenase ALDH; EC 1.2.1.3 from Emericella nidulans (see 5 papers)
    41% identity, 97% coverage of query (340 bits)

cymC / O33455 cumic aldehyde dehydrogenase (EC 1.2.1.29) from Pseudomonas putida (see paper)
cymc / AAB62298.1 p-cumic aldehyde dehydrogenase from Pseudomonas putida (see 3 papers)
    39% identity, 95% coverage of query (339 bits)

ALDH1_ELEED / Q28399 Aldehyde dehydrogenase, cytosolic 1; ALDH class 1; ETA-crystallin; EC 1.2.1.3 from Elephantulus edwardii (Cape long-eared elephant shrew) (see paper)
Q28399 retinal dehydrogenase (EC 1.2.1.36) from Elephantulus edwardii (see paper)
    39% identity, 97% coverage of query (339 bits)

1o9jA / Q28399 The x-ray crystal structure of eta-crystallin (see paper)
    39% identity, 97% coverage of query (339 bits)

4pz2B / W8SZG1 Structure of zm aldh2-6 (rf2f) in complex with NAD (see paper)
    41% identity, 95% coverage of query (338 bits)

AL2B4_ARATH / Q9SU63 Aldehyde dehydrogenase family 2 member B4, mitochondrial; ALDH2a; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    38% identity, 96% coverage of query (337 bits)

P30837 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 2 papers)
    40% identity, 97% coverage of query (335 bits)

7mjcA / P30837 Crystal structure analysis of aldh1b1
    40% identity, 97% coverage of query (335 bits)

7radA Crystal structure analysis of aldh1b1
    40% identity, 97% coverage of query (335 bits)

7mjdA Crystal structure analysis of aldh1b1
    40% identity, 97% coverage of query (335 bits)

Q0H2G3 retinal dehydrogenase (EC 1.2.1.36) from Danio rerio (see paper)
    39% identity, 97% coverage of query (334 bits)

BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
    38% identity, 97% coverage of query (334 bits)

Q9LRI6 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
    41% identity, 97% coverage of query (333 bits)

Q9FAB1 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Geobacillus thermoleovorans (see paper)
    39% identity, 98% coverage of query (332 bits)

ALD5 aldehyde dehydrogenase from Candida albicans (see paper)
    38% identity, 95% coverage of query (332 bits)

betB / P54222 betaine aldehyde dehydrogenase (EC 1.2.1.8) from Rhizobium meliloti (strain 1021) (see 2 papers)
    39% identity, 97% coverage of query (332 bits)

Q9CZS1 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 2 papers)
    40% identity, 97% coverage of query (330 bits)

4v37A / P17202 Crystal structure of betaine aldehyde dehydrogenase from spinach showing a thiohemiacetal with 3-aminopropionaldehyde
    38% identity, 97% coverage of query (330 bits)

BALDH_ANTMA / C7A2A0 Benzaldehyde dehydrogenase, mitochondrial; 2-phenylacetaldehyde dehydrogenase; Acetaldehyde dehydrogenase; EC 1.2.1.28; EC 1.2.1.39; EC 1.2.1.3 from Antirrhinum majus (Garden snapdragon) (see paper)
    39% identity, 95% coverage of query (330 bits)

YdbG / b1385 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
feaB / P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (strain K12) (see 10 papers)
P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (see 3 papers)
    38% identity, 96% coverage of query (329 bits)

padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
    38% identity, 96% coverage of query (329 bits)

P27463 retinal dehydrogenase (EC 1.2.1.36) from Gallus gallus (see 2 papers)
    39% identity, 97% coverage of query (327 bits)

Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
    39% identity, 97% coverage of query (327 bits)

AL1A1_RABIT / Q8MI17 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Oryctolagus cuniculus (Rabbit) (see paper)
    37% identity, 97% coverage of query (327 bits)

8skfA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (lattice translocation disorder)
    38% identity, 97% coverage of query (327 bits)

AL1A1_RAT / P51647 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Rattus norvegicus (Rat) (see 3 papers)
P51647 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see 5 papers)
    39% identity, 97% coverage of query (325 bits)

4fr8C / P05091 Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin (see paper)
    39% identity, 96% coverage of query (325 bits)

ALDH2 / P05091 mitochondrial aldehyde dehydrogenase subunit (EC 1.2.1.3; EC 1.2.1.39) from Homo sapiens (see 14 papers)
ALDH2_HUMAN / P05091 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Homo sapiens (Human) (see 3 papers)
P05091 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 13 papers)
    39% identity, 97% coverage of query (325 bits)

7rluA / P28037 Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
    37% identity, 96% coverage of query (325 bits)

A0A0A7PB40 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Sphingopyxis fribergensis (see paper)
    39% identity, 96% coverage of query (325 bits)

4fr8A Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin
    39% identity, 97% coverage of query (325 bits)

8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
    38% identity, 96% coverage of query (325 bits)

8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
    38% identity, 96% coverage of query (325 bits)

8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
    38% identity, 96% coverage of query (325 bits)

8vqwC Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (coa bound)
    38% identity, 96% coverage of query (325 bits)

8vj3A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (fad bound)
    38% identity, 96% coverage of query (325 bits)

8uzoA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (adp bound)
    38% identity, 96% coverage of query (325 bits)

8uznA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (amp bound)
    38% identity, 96% coverage of query (325 bits)

8uzmA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADPH bound)
    38% identity, 96% coverage of query (325 bits)

8uzkA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADP+ bound)
    38% identity, 96% coverage of query (325 bits)

4go2A Crystal structure of thE C-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with thio-NADP
    37% identity, 96% coverage of query (325 bits)

2o2rA Crystal structure of thE C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
    37% identity, 96% coverage of query (325 bits)

5l13A Structure of aldh2 in complex with 2p3
    39% identity, 97% coverage of query (325 bits)

4kwgA Crystal structure analysis of aldh2+aldib13
    39% identity, 97% coverage of query (325 bits)

4kwfA Crystal structure analysis of aldh2+aldib33
    39% identity, 97% coverage of query (325 bits)

3sz9A Crystal structure of human aldh2 modified with the beta-elimination product of aldi-3; 1-(4-ethylbenzene)prop-2-en-1-one
    39% identity, 97% coverage of query (325 bits)

3injA Human mitochondrial aldehyde dehydrogenase complexed with agonist alda-1
    39% identity, 97% coverage of query (325 bits)

2vleA The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
    39% identity, 97% coverage of query (325 bits)

1o01B Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(h) and mg2+
    39% identity, 97% coverage of query (325 bits)

1cw3A Human mitochondrial aldehyde dehydrogenase complexed with NAD+ and mn2+
    39% identity, 97% coverage of query (325 bits)

AL1A1_MOUSE / P24549 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Mus musculus (Mouse) (see 4 papers)
P24549 retinal dehydrogenase (EC 1.2.1.36) from Mus musculus (see 3 papers)
    38% identity, 97% coverage of query (324 bits)

ALDH1A1 / P00352 retinal dehydrogenase 1 (EC 1.2.1.36) from Homo sapiens (see 10 papers)
AL1A1_HUMAN / P00352 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Homo sapiens (Human) (see 7 papers)
P00352 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
    38% identity, 98% coverage of query (324 bits)

AL1L1_RAT / P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 7 papers)
P28037 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Rattus norvegicus (see 3 papers)
    37% identity, 96% coverage of query (324 bits)

4wb9A Human aldh1a1 complexed with nadh
    38% identity, 98% coverage of query (324 bits)

5teiA Structure of human aldh1a1 with inhibitor cm039
    38% identity, 98% coverage of query (324 bits)

4x4lA Structure of human aldh1a1 with inhibitor cm037
    38% identity, 98% coverage of query (324 bits)

8t0tA Structure of compound 4 bound to human aldh1a1
    38% identity, 98% coverage of query (324 bits)

7um9A Human aldh1a1 with bound compound cm38
    38% identity, 98% coverage of query (324 bits)

5l2oA Crystal structure of aldh1a1 in complex with buc22
    38% identity, 98% coverage of query (324 bits)

5l2nA Structure of aldh1a1 in complex with buc25
    38% identity, 98% coverage of query (324 bits)

5l2mA Structure of aldh1a1 in complex with buc11
    38% identity, 98% coverage of query (324 bits)

4wpnA Structure of human aldh1a1 with inhibitor cm053
    38% identity, 98% coverage of query (324 bits)

8t0nA Structure of compound 4 bound to human aldh1a1
    38% identity, 98% coverage of query (324 bits)

7jwwA Crystal structure of human aldh1a1 bound to compound (r)-28
    38% identity, 98% coverage of query (324 bits)

7jwvA Crystal structure of human aldh1a1 bound to compound (r)-28
    38% identity, 98% coverage of query (324 bits)

7jwuA Crystal structure of human aldh1a1 bound to compound (r)-28
    38% identity, 98% coverage of query (324 bits)

7jwtA Crystal structure of human aldh1a1 bound to compound (r)-28
    38% identity, 98% coverage of query (324 bits)

7jwsA Crystal structure of human aldh1a1 bound to compound (r)-28
    38% identity, 98% coverage of query (324 bits)

6dumA Aldh1a1 n121s in complex with 6-{[(3-fluorophenyl)methyl]sulfanyl}-2- (oxetan-3-yl)-5-phenyl-2,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one (compound 13g)
    38% identity, 98% coverage of query (324 bits)

Build an alignment

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory