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Searching for up to 100 curated homologs for WP_010538804.1 NCBI__GCF_000226135.1:WP_010538804.1 (581 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pgcA / P18159 α-phosphoglucomutase (EC 5.4.2.2) from Bacillus subtilis (strain 168) (see paper)
PGCA_BACSU / P18159 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
    45% identity, 93% coverage of query (479 bits)

pgmA / CAB96418.1 phosphoglucomutase from Streptococcus thermophilus (see paper)
    42% identity, 94% coverage of query (429 bits)

PGCA_STAA8 / Q2FVC1 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    37% identity, 93% coverage of query (325 bits)

PGM2 / Q96G03 phosphoglucomutase-2 (EC 5.4.2.2; EC 5.4.2.7) from Homo sapiens (see 2 papers)
PGM2_HUMAN / Q96G03 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-2; EC 5.4.2.7; EC 5.4.2.2 from Homo sapiens (Human) (see 2 papers)
    35% identity, 94% coverage of query (324 bits)

PGM2_MOUSE / Q7TSV4 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-1; Phosphoglucomutase-2; PGM 2; EC 5.4.2.7; EC 5.4.2.2 from Mus musculus (Mouse) (see paper)
    33% identity, 94% coverage of query (318 bits)

PGM3_SCHPO / O74478 Probable phosphoribomutase; PRM; Phosphoglucomutase 3 homolog; PGM 3 homolog; EC 5.4.2.7 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    32% identity, 94% coverage of query (285 bits)

PGM2L_HUMAN / Q6PCE3 Glucose 1,6-bisphosphate synthase; PMMLP; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Homo sapiens (Human) (see 3 papers)
    32% identity, 92% coverage of query (283 bits)

PGM2L_MOUSE / Q8CAA7 Glucose 1,6-bisphosphate synthase; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Mus musculus (Mouse) (see paper)
    32% identity, 93% coverage of query (279 bits)

PGM3_YEAST / Q03262 Phosphoribomutase; PRM; Phosphoglucomutase 3; PGM 3; EC 5.4.2.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    33% identity, 94% coverage of query (269 bits)

C6L2F4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Toxoplasma gondii (see paper)
    32% identity, 92% coverage of query (262 bits)

Build an alignment

Build an alignment for WP_010538804.1 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PGMMM_THEKO / Q68BJ6 Phosphoglucomutase/phosphomannomutase; PGM/PMM; EC 5.4.2.2; EC 5.4.2.8 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    27% identity, 87% coverage of query (120 bits)

celB / AAA21561.1 phosphoglucomutase from Komagataeibacter xylinus (see paper)
    25% identity, 88% coverage of query (87.0 bits)

ST0242 / Q976E4 hexose-6-phosphate mutase/isomerase (EC 5.3.1.8; EC 5.3.1.9; EC 5.4.2.10; EC 5.4.2.13) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see paper)
PGMUT_SULTO / Q976E4 Phosphoglucosamine/phosphogalactosamine mutase; PGlcNM; EC 5.4.2.10; EC 5.4.2.13 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q976E4 phosphogalactosamine mutase (EC 5.4.2.13) from Sulfurisphaera tokodaii (see paper)
    23% identity, 88% coverage of query (85.5 bits)

2fuvA / Q8ZQW9 Phosphoglucomutase from salmonella typhimurium.
    26% identity, 86% coverage of query (80.1 bits)

A0A0H3NJ17 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
Q8ZQW9 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    26% identity, 86% coverage of query (79.7 bits)

Blu / b0688 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
pgm / P36938 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli (strain K12) (see 11 papers)
PGM_ECOLI / P36938 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Escherichia coli (strain K12) (see 2 papers)
pgm / GB|ABB65241.1 phosphoglucomutase; EC 5.4.2.2 from Escherichia coli K12 (see 6 papers)
    24% identity, 86% coverage of query (74.7 bits)

Q81VN7 phosphoglucosamine mutase (EC 5.4.2.10) from Bacillus anthracis (see paper)
    22% identity, 91% coverage of query (74.3 bits)

P74027 glucose-1,6-bisphosphate synthase from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    25% identity, 78% coverage of query (70.5 bits)

pgmA / I6Y2G3 phosphoglucomutase (EC 5.4.2.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
I6Y2G3 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Mycobacterium tuberculosis (see paper)
    24% identity, 88% coverage of query (68.2 bits)

A0A2H5BEG8 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Ganoderma lucidum (see paper)
    24% identity, 89% coverage of query (66.2 bits)

7pjcB / A0A1D8PSA9 The structure of candida albicans phosphoglucomutase with isothiazolone modification on cys359
    24% identity, 87% coverage of query (64.7 bits)

7p5oB / Q4WY53 Crystal structure of aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
    25% identity, 78% coverage of query (60.8 bits)

7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound)
    23% identity, 87% coverage of query (60.1 bits)

7ojrA / O34824 Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
    23% identity, 87% coverage of query (60.1 bits)

6snoA / P36871 Crystal structures of human pgm1 isoform 2 (see paper)
    25% identity, 86% coverage of query (57.4 bits)

6snqA Crystal structures of human pgm1 isoform 2
    25% identity, 87% coverage of query (57.4 bits)

PGM1 / P36871 phosphoglucomutase-1 (EC 5.4.2.2) from Homo sapiens (see 3 papers)
PGM1_HUMAN / P36871 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Homo sapiens (Human) (see 8 papers)
P36871 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Homo sapiens (see 4 papers)
    24% identity, 85% coverage of query (54.3 bits)

5jn5A Crystal structure of the d263y missense variant of human pgm1
    24% identity, 87% coverage of query (53.1 bits)

7s0wB / P36871 Crystal structure of the t337m variant of human pgm-1 (see paper)
    24% identity, 70% coverage of query (50.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory