Searching for up to 100 curated homologs for WP_010875114.1 NCBI__GCF_000018545.1:WP_010875114.1 (336 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
uptG / AAK53485.1 cystathionine beta-lyase from Xanthomonas campestris pv. campestris (see 4 papers)
35% identity, 94% coverage of query (182 bits)
Q9EYM7 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Streptomyces venezuelae (see paper)
37% identity, 96% coverage of query (167 bits)
8s5hA / P35520 Full-length human cystathionine beta-synthase with c-terminal 6xhis- tag, basal state, helical reconstruction (see paper)
33% identity, 97% coverage of query (165 bits)
CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
33% identity, 97% coverage of query (164 bits)
7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
33% identity, 97% coverage of query (164 bits)
4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
34% identity, 93% coverage of query (164 bits)
MCCA_BACSU / O05393 O-acetylserine dependent cystathionine beta-synthase; EC 2.5.1.134 from Bacillus subtilis (strain 168) (see paper)
36% identity, 89% coverage of query (162 bits)
1jbqA Structure of human cystathionine beta-synthase: a unique pyridoxal 5'- phosphate dependent hemeprotein
34% identity, 93% coverage of query (162 bits)
Cbs / P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus (see 2 papers)
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat) (see 3 papers)
32% identity, 96% coverage of query (161 bits)
CYS4 / P32582 Cys4 (EC 4.2.1.22) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
CBS_YEAST / P32582 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; Sulfur transfer protein 4; EC 4.2.1.22 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32582 cystathionine beta-synthase (EC 4.2.1.22) from Saccharomyces cerevisiae (see 3 papers)
34% identity, 96% coverage of query (159 bits)
F9UT54 cysteine synthase (EC 2.5.1.47); cystathionine beta-synthase (EC 4.2.1.22) from Lactiplantibacillus plantarum (see paper)
36% identity, 90% coverage of query (158 bits)
6c2hA / P32582 Crystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of the catalytic core (see paper)
34% identity, 96% coverage of query (156 bits)
6c4pA Crystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of the pmp complex
34% identity, 96% coverage of query (156 bits)
6c2zA Crystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of the plp-aminoacrylate intermediate
34% identity, 96% coverage of query (156 bits)
6c2qA Crystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of the plp-l-serine intermediate
34% identity, 96% coverage of query (156 bits)
5b1iA / F9UT54 Crystal structure of k42a mutant of cystathionine beta-synthase from lactobacillus plantarum in a complex with l-methionine (see paper)
36% identity, 90% coverage of query (155 bits)
5ohxA / Q2V0C9 Structure of active cystathionine b-synthase from apis mellifera (see paper)
34% identity, 96% coverage of query (154 bits)
CBS_APIME / Q2V0C9 Cystathionine beta-synthase; EC 4.2.1.22 from Apis mellifera (Honeybee) (see paper)
Q2V0C9 cystathionine beta-synthase (EC 4.2.1.22) from Apis mellifera (see paper)
34% identity, 96% coverage of query (152 bits)
6xwlC / A0A125YSJ9 Cystathionine beta-synthase from toxoplasma gondii (see paper)
35% identity, 92% coverage of query (152 bits)
6xylA Crystal structure of delta466-491 cystathionine beta-synthase from toxoplasma gondii with l-serine
35% identity, 92% coverage of query (151 bits)
mecA cystathionine beta-synthase; EC 4.2.1.22 from Emericella nidulans (see 2 papers)
35% identity, 96% coverage of query (150 bits)
sbnA / Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
SBNA_STAAE / A6QDA0 N-(2-amino-2-carboxyethyl)-L-glutamate synthase; ACEGA synthase; Staphyloferrin B biosynthesis protein SbnA; EC 2.5.1.140 from Staphylococcus aureus (strain Newman) (see 3 papers)
SBNA_STAA8 / Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase; ACEGA synthase; Staphyloferrin B biosynthesis protein SbnA; EC 2.5.1.140 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
A6QDA0 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (see 2 papers)
Q2G1N3 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Staphylococcus aureus (see paper)
30% identity, 93% coverage of query (150 bits)
5d84A / A6QDA0 Staphyloferrin b precursor biosynthetic enzyme sbna bound to plp (see paper)
30% identity, 93% coverage of query (150 bits)
5d85A Staphyloferrin b precursor biosynthetic enzyme sbna bound to aminoacrylate intermediate
30% identity, 93% coverage of query (150 bits)
6vjuB / Q5ZRD1 Crystal structure of cystathionine beta synthase from legionella pneumophila with llp, plp, and homocysteine
34% identity, 94% coverage of query (149 bits)
5d86A Staphyloferrin b precursor biosynthetic enzyme sbna y152f variant
30% identity, 93% coverage of query (149 bits)
cysK / P56067 cystathionine β-synthase (O-acetyl-L-serine) monomer (EC 4.2.1.22; EC 2.5.1.134; EC 2.5.1.47) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
6ahiB / P56067 Crystal structure of o-acetylserine dependent cystathionine beta- synthase from helicobacter pylori. (see paper)
33% identity, 90% coverage of query (148 bits)
CS1 / A2EI82 O-phosphoserine sulfhydrylase monomer (EC 2.5.1.47; EC 2.5.1.65) from Trichomonas vaginalis (strain ATCC PRA-98 / G3) (see paper)
33% identity, 92% coverage of query (148 bits)
CYSK_BACSU / P37887 Cysteine synthase; CSase; O-acetylserine (thiol)-lyase; OAS-TL; Superoxide-inducible protein 11; SOI11; EC 2.5.1.47 from Bacillus subtilis (strain 168) (see 3 papers)
P37887 cysteine synthase (EC 2.5.1.47) from Bacillus subtilis (see paper)
38% identity, 90% coverage of query (147 bits)
A2GMG5 cysteine synthase (EC 2.5.1.47) from Trichomonas vaginalis (see paper)
33% identity, 92% coverage of query (146 bits)
CBS / A0A563XPB1 cystathionine β-synthase (EC 4.2.1.22) from Gallus gallus (see 7 papers)
35% identity, 91% coverage of query (146 bits)
Y1077_MYCTU / P9WP51 Probable cystathionine beta-synthase Rv1077; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
35% identity, 96% coverage of query (144 bits)
7xnzB / P9WP51 Native cystathionine beta-synthase of mycobacterium tuberculosis. (see paper)
35% identity, 96% coverage of query (144 bits)
A0A220K8D2 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi (see paper)
34% identity, 89% coverage of query (144 bits)
7xoyA Cystathionine beta-synthase of mycobacterium tuberculosis in the presence of s-adenosylmethionine and serine.
35% identity, 96% coverage of query (144 bits)
sulH / A0A1I9RH08 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Paraburkholderia acidicola (see paper)
30% identity, 92% coverage of query (143 bits)
7mfjBBB / T1KF23 7mfjBBB (see paper)
34% identity, 87% coverage of query (142 bits)
T1KF23 L-3-cyanoalanine synthase (EC 4.4.1.9) from Tetranychus urticae (see paper)
34% identity, 87% coverage of query (142 bits)
A0A220K8D1 L-3-cyanoalanine synthase (EC 4.4.1.9) from Anthocharis cardamines (see paper)
34% identity, 87% coverage of query (142 bits)
E5LPF4 cysteine synthase (EC 2.5.1.47) from Lacticaseibacillus casei (see paper)
38% identity, 89% coverage of query (141 bits)
A0A220K8F1 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi (see paper)
33% identity, 88% coverage of query (139 bits)
A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max (see paper)
35% identity, 89% coverage of query (138 bits)
A0A220K813 L-3-cyanoalanine synthase (EC 4.4.1.9) from Spodoptera littoralis (see paper)
33% identity, 92% coverage of query (137 bits)
A0A0U3SCD8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae (see paper)
34% identity, 88% coverage of query (137 bits)
6xo2A / T1KF23 Structural characterization of beta cyanoalanine synthase from tetranychus urticae (two-spotted spider mite) (see paper)
33% identity, 87% coverage of query (137 bits)
A0A0U3QZ45 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae (see paper)
33% identity, 89% coverage of query (137 bits)
2ecoA / Q5SLE6 Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-methylvalerate
40% identity, 88% coverage of query (136 bits)
2efyA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-acetylbutyric acid
40% identity, 88% coverage of query (136 bits)
2ecqA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 3-hydroxylactate
40% identity, 88% coverage of query (136 bits)
A0A220K8B9 L-3-cyanoalanine synthase (EC 4.4.1.9) from Plutella xylostella (see paper)
35% identity, 88% coverage of query (135 bits)
Q9VRD9 cystathionine beta-synthase (EC 4.2.1.22) from Drosophila melanogaster (see paper)
32% identity, 94% coverage of query (135 bits)
3pc3A / Q9VRD9 Full length structure of cystathionine beta-synthase from drosophila in complex with aminoacrylate (see paper)
32% identity, 94% coverage of query (135 bits)
W5S3I4 cysteine synthase (EC 2.5.1.47) from Leucaena leucocephala (see paper)
34% identity, 90% coverage of query (135 bits)
cysK / CAA90597.1 cysteine synthase from Flavobacterium sp (see paper)
35% identity, 79% coverage of query (135 bits)
3pc2A Full length structure of cystathionine beta-synthase from drosophila
32% identity, 94% coverage of query (135 bits)
3pc4A Full length structure of cystathionine beta-synthase from drosophila in complex with serine
32% identity, 94% coverage of query (135 bits)
A0A220K8C9 L-3-cyanoalanine synthase (EC 4.4.1.9) from Anthocharis cardamines (see paper)
32% identity, 89% coverage of query (134 bits)
A0A220K8D8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Anthocharis cardamines (see paper)
33% identity, 89% coverage of query (134 bits)
CYSK2_CAEEL / O45679 Bifunctional L-3-cyanoalanine synthase/cysteine synthase; CAS; O-acetylserine (thiol)-lyase 2; OAS-TL; EC 2.5.1.47; EC 4.4.1.9 from Caenorhabditis elegans (see 3 papers)
O45679 cysteine synthase (EC 2.5.1.47) from Caenorhabditis elegans (see 2 papers)
32% identity, 90% coverage of query (133 bits)
CYSK_EMENI / P50867 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
cysB / GB|AAC06128.1 cysteine synthase; EC 2.5.1.47 from Emericella nidulans (see 3 papers)
30% identity, 96% coverage of query (133 bits)
Cy-OASTL / A0A2Z6G0Q7 mimosine synthase monomer (EC 2.5.1.47; EC 2.5.1.52) from Leucaena leucocephala (see 2 papers)
A0A2Z6G0Q7 cysteine synthase (EC 2.5.1.47) from Leucaena leucocephala (see paper)
34% identity, 90% coverage of query (132 bits)
A0A220K819 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus (see paper)
32% identity, 87% coverage of query (132 bits)
O81155 cysteine synthase (EC 2.5.1.47) from Solanum tuberosum (see paper)
35% identity, 94% coverage of query (132 bits)
CBS1_CAEEL / G5EFH8 Cystathionine beta-synthase cbs-1; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Caenorhabditis elegans (see 2 papers)
33% identity, 93% coverage of query (132 bits)
2bhtA / P16703 Crystal structure of o-acetylserine sulfhydrylase b (see paper)
32% identity, 91% coverage of query (131 bits)
A0A220K835 L-3-cyanoalanine synthase (EC 4.4.1.9) from Spodoptera littoralis (see paper)
31% identity, 89% coverage of query (131 bits)
cysB / AAC06128.1 cysteine synthase from Aspergillus nidulans (see paper)
30% identity, 95% coverage of query (130 bits)
CysM / b2421 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
cysM / P16703 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1) from Escherichia coli (strain K12) (see 15 papers)
CYSM_ECOLI / P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
32% identity, 92% coverage of query (130 bits)
A0A220K8E3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus (see paper)
33% identity, 89% coverage of query (130 bits)
A0A220K8A8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Zygaena filipendulae (see paper)
31% identity, 89% coverage of query (130 bits)
A0A220K8J3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi (see paper)
31% identity, 89% coverage of query (130 bits)
2q3dA / P9WP55 2.2 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) from mycobacterium tuberculosis in complex with the reaction intermediate alpha-aminoacrylate (see paper)
36% identity, 89% coverage of query (129 bits)
CYSK_MYCTU / P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WP55 cysteine synthase (EC 2.5.1.47) from Mycobacterium tuberculosis (see 3 papers)
36% identity, 89% coverage of query (129 bits)
ddaA / E2JA26 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (EC 2.5.1.140) from Enterobacter agglomerans (see 2 papers)
30% identity, 85% coverage of query (129 bits)
A0A0F6AQU1 cysteine synthase (EC 2.5.1.47) from Brucella abortus (see paper)
30% identity, 95% coverage of query (128 bits)
P29848 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) (EC 2.5.1.144); cysteine synthase (EC 2.5.1.47) from Salmonella enterica subsp. enterica serovar Typhimurium (see 9 papers)
31% identity, 92% coverage of query (128 bits)
3zeiA Structure of the mycobacterium tuberculosis o-acetylserine sulfhydrylase (oass) cysk1 in complex with a small molecule inhibitor
36% identity, 88% coverage of query (127 bits)
2q3cA 2.1 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) holoenzyme from mycobacterium tuberculosis in complex with the inhibitory peptide dfsi
36% identity, 88% coverage of query (127 bits)
7n2tA / Q43317 O-acetylserine sulfhydrylase from citrullus vulgaris in the internal aldimine state, with citrate bound (see paper)
36% identity, 90% coverage of query (127 bits)
4aecA / Q43725 Crystal structure of the arabidopsis thaliana o-acetyl-serine-(thiol)- lyasE C (see paper)
36% identity, 89% coverage of query (126 bits)
4lmaA / A8YBS4 Crystal structure analysis of o-acetylserine sulfhydrylase cysk1 from microcystis aeruginosa 7806 (see paper)
34% identity, 90% coverage of query (125 bits)
8if7A / A6YEH3 Crystal structure of cmnb (see paper)
33% identity, 90% coverage of query (125 bits)
CYSK1_CAEEL / Q93244 Cysteine synthase 1; O-acetylserine (thiol)-lyase 1; OAS-TL; EC 2.5.1.47 from Caenorhabditis elegans (see 3 papers)
Q93244 cysteine synthase (EC 2.5.1.47) from Caenorhabditis elegans (see 2 papers)
34% identity, 88% coverage of query (125 bits)
OASB / P47999 O-acetylserine (thiol) lyase (EC 2.5.1.47) from Arabidopsis thaliana (see 3 papers)
CYSKP_ARATH / P47999 Cysteine synthase, chloroplastic/chromoplastic; At.OAS.7-4; Beta-substituted Ala synthase 2;1; ARAth-Bsas2;1; CSase B; AtCS-B; CS-B; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL B; cpACS1; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P47999 cysteine synthase (EC 2.5.1.47) from Arabidopsis thaliana (see 2 papers)
35% identity, 88% coverage of query (124 bits)
4lmbA / A8YBP8 Crystal structure analysis of o-acetylserine sulfhydrylase cysk2 complexed with cystine from microcystis aeruginosa 7806 (see paper)
35% identity, 90% coverage of query (122 bits)
5xoqA / D5STP0 Crystal structure of o-acetylserine sulfhydrylase with bound transcription factor peptide inhibitor from planctomyces limnophilus
34% identity, 90% coverage of query (122 bits)
3x43A Crystal structure of o-ureido-l-serine synthase
31% identity, 93% coverage of query (122 bits)
dcsD / D2Z027 O-ureido-L-serine synthase (EC 2.5.1.47; EC 2.6.99.3) from Streptomyces lavendulae (see 2 papers)
DCSD_STRLA / D2Z027 O-ureido-L-serine synthase; Cysteine synthase homolog DscD; O-acetylserine sulfhydrylase; EC 2.6.99.3; EC 2.5.1.47 from Streptomyces lavendulae (see 3 papers)
D2Z027 cysteine synthase (EC 2.5.1.47); O-ureido-L-serine synthase (EC 2.6.99.3) from Streptomyces lavendulae (see 4 papers)
31% identity, 93% coverage of query (122 bits)
6kr5B / Q401L7 Crystal structure of o-acetyl serine sulfhydrylase isoform 3 from entamoeba histolytica (see paper)
31% identity, 94% coverage of query (120 bits)
5xemA / Q8RE94 Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-lanthionine-plp schiff base
31% identity, 90% coverage of query (120 bits)
5xenA Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-serine-plp schiff base
32% identity, 90% coverage of query (119 bits)
3x44A / D2Z027 Crystal structure of o-ureido-l-serine-bound k43a mutant of o-ureido- l-serine synthase (see paper)
31% identity, 93% coverage of query (119 bits)
3t4pA / G1C2I2 Crystal structure of o-acetyl serine sulfhydrylase from leishmania donovani in complex with designed tetrapeptide (see paper)
34% identity, 89% coverage of query (117 bits)
3vbeC / I1L6I6 Crystal structure of beta-cyanoalanine synthase in soybean (see paper)
30% identity, 93% coverage of query (115 bits)
4jblB Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with methionine
30% identity, 90% coverage of query (113 bits)
3bm5B Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine
30% identity, 90% coverage of query (113 bits)
4jbnA Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with serine acetyl transferase derived tetrapeptide, spsi
30% identity, 90% coverage of query (113 bits)
4il5A Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with isoleucine
30% identity, 90% coverage of query (113 bits)
3bm5A / O15570 Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
30% identity, 90% coverage of query (113 bits)
3vc3A Crystal structure of beta-cyanoalanine synthase k95a mutant in soybean
30% identity, 93% coverage of query (112 bits)
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