Searching for up to 100 curated homologs for WP_010876479.1 NCBI__GCF_000008645.1:WP_010876479.1 (334 a.a.)
Found high-coverage hits (≥70%) to 32 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lysY / Q4JAQ3 [amino-group carrier protein]-L-2-aminoadipate/[amino-group carrier protein]-L-glutamate phosphate reductase (EC 1.2.1.103; EC 1.2.1.106) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4JAQ3 [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Sulfolobus acidocaldarius (see paper)
45% identity, 100% coverage of query (279 bits)
ARGC_GEOSE / Q07906 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
42% identity, 100% coverage of query (265 bits)
Q5JFW1 [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Thermococcus kodakarensis (see paper)
43% identity, 100% coverage of query (252 bits)
ARGC_ARATH / Q93Z70 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Arabidopsis thaliana (Mouse-ear cress)
42% identity, 100% coverage of query (252 bits)
ARGC_ORYSJ / Q6AV34 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Oryza sativa subsp. japonica (Rice) (see paper)
40% identity, 100% coverage of query (249 bits)
lysY / O50146 [amino-group carrier protein]-L-2-aminoadipate 6-phosphate reductase (EC 1.2.1.103) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
LYSY_THET2 / O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
O50146 [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase (EC 1.2.1.103); [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Thermus thermophilus (see paper)
36% identity, 99% coverage of query (201 bits)
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
36% identity, 99% coverage of query (201 bits)
CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) from Pedobacter sp. GW460-11-11-14-LB5
37% identity, 99% coverage of query (198 bits)
ArgC / b3958 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
argC / P11446 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli (strain K12) (see 4 papers)
ARGC_ECOLI / P11446 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Escherichia coli (strain K12) (see paper)
P11446 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) from Escherichia coli (see paper)
38% identity, 98% coverage of query (190 bits)
BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Bacteroides thetaiotaomicron VPI-5482
37% identity, 98% coverage of query (189 bits)
5einA / O50146 Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
36% identity, 99% coverage of query (189 bits)
argC / CAB82479.1 N-acetyl-gamma-glutamyl-phosphate reductase from Streptomyces clavuligerus (see 3 papers)
39% identity, 100% coverage of query (186 bits)
argC / CAB95020.1 n-acetylglutamate 5-semialdehyde dehydrogenase from Moritella abyssi (see paper)
35% identity, 98% coverage of query (183 bits)
Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
38% identity, 98% coverage of query (178 bits)
ABZR86_RS08700 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Dyella japonica UNC79MFTsu3.2
34% identity, 99% coverage of query (174 bits)
ARG5,6 arginine biosynthetic enzyme activities from Candida albicans (see 3 papers)
34% identity, 97% coverage of query (169 bits)
2i3gA / P9WPZ9 Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
36% identity, 99% coverage of query (166 bits)
P9WPZ9 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) from Mycobacterium tuberculosis (see paper)
36% identity, 99% coverage of query (166 bits)
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
36% identity, 99% coverage of query (166 bits)
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
36% identity, 99% coverage of query (166 bits)
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
36% identity, 99% coverage of query (166 bits)
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
36% identity, 99% coverage of query (166 bits)
ARG56_SCHPO / P31318 Protein arg11, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
arg11 / GI|1204210 N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (see 2 papers)
32% identity, 97% coverage of query (150 bits)
ARG56_YEAST / Q01217 Protein ARG5,6, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
Q01217 acetylglutamate kinase (EC 2.7.2.8) from Saccharomyces cerevisiae (see paper)
ARG5,6 / CAA40336.1 acetylglutamate kinase from Saccharomyces cerevisiae (see paper)
32% identity, 97% coverage of query (137 bits)
Build an alignment for WP_010876479.1 and 24 homologs with ≥ 30% identity
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Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sphingomonas koreensis DSMZ 15582
26% identity, 98% coverage of query (77.8 bits)
SMc01801 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sinorhizobium meliloti 1021
28% identity, 76% coverage of query (75.1 bits)
argC / CAC29374.1 acetylglutamylphosphate reductase from Rhizobium etli (see paper)
26% identity, 94% coverage of query (69.7 bits)
Msed_0709 / A4YEN2 succinyl-CoA reductase (NADPH) subunit (EC 1.2.1.75; EC 1.2.1.76) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 3 papers)
MCR_METS5 / A4YEN2 Malonyl CoA reductase (NADP); NADP-dependent malonyl CoA reductase; EC 1.2.1.75 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
23% identity, 95% coverage of query (58.5 bits)
mcr / Q96YK1 malonyl-CoA reductase subunit (EC 1.2.1.75) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see paper)
MCR_SULTO / Q96YK1 Malonyl-CoA reductase; EC 1.2.1.75 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96YK1 malonyl-CoA reductase (malonate semialdehyde-forming) (EC 1.2.1.75) from Sulfurisphaera tokodaii (see 3 papers)
24% identity, 91% coverage of query (53.1 bits)
4dpkA / Q96YK1 Structure of malonyl-coenzyme a reductase from crenarchaeota (see paper)
24% identity, 91% coverage of query (53.1 bits)
4dpmA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with coa
24% identity, 91% coverage of query (53.1 bits)
4dplA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with NADP
24% identity, 91% coverage of query (53.1 bits)
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Lawrence Berkeley National Laboratory