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Searching for up to 100 curated homologs for WP_010876999.1 NCBI__GCF_000008645.1:WP_010876999.1 (162 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

leuD / Q58673 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
LEUD_METJA / Q58673 Isopropylmalate/citramalate isomerase small subunit; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; EC 4.2.1.33; EC 4.2.1.35; EC 4.2.1.31 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58673 3-isopropylmalate dehydratase (EC 4.2.1.33) from Methanocaldococcus jannaschii (see paper)
    68% identity, 97% coverage of query (221 bits)

dmdB / Q0QLE1 dimethylmaleate hydratase subunit B (EC 4.2.1.85) from Eubacterium barkeri (see paper)
DMDB_EUBBA / Q0QLE1 2,3-dimethylmalate dehydratase small subunit; EC 4.2.1.85 from Eubacterium barkeri (Clostridium barkeri) (see 2 papers)
    51% identity, 96% coverage of query (177 bits)

O59393 3-isopropylmalate dehydratase (EC 4.2.1.33) from Pyrococcus horikoshii (see paper)
    54% identity, 98% coverage of query (169 bits)

hacB / Q58667 homoaconitase β subunit (EC 4.2.1.36) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
HACB_METJA / Q58667 Methanogen homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.114 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 3 papers)
    54% identity, 97% coverage of query (158 bits)

2pkpA / Q58667 Crystal structure of 3-isopropylmalate dehydratase (leud)from methhanocaldococcus jannaschii dsm2661 (mj1271) (see paper)
    54% identity, 97% coverage of query (157 bits)

DVU2983 3-isopropylmalate dehydratase / (R)-citramalate isomerase, small subunit LeuD (EC 4.2.1.33; EC 4.2.1.35) from Desulfovibrio vulgaris Hildenborough JW710
    49% identity, 96% coverage of query (155 bits)

lysU / Q9ZND9 homoaconitase small subunit (EC 4.2.1.36) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
HACB_THET2 / Q9ZND9 Homoaconitase small subunit; HACN; Homoaconitate hydratase; EC 4.2.1.36 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
    46% identity, 98% coverage of query (149 bits)

AMT8_ALTAL / C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    40% identity, 98% coverage of query (100 bits)

AMT82_ALTAL / C9K7I3 Aconitase AMT8-2; AM-toxin biosynthesis protein 8-2; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    39% identity, 98% coverage of query (94.7 bits)

lysF / GI|1628374 homoaconitase, mitochondrial; EC 4.2.1.36 from Emericella nidulans (see paper)
    36% identity, 90% coverage of query (94.0 bits)

LYS4_EMENI / Q92412 Homoaconitase, mitochondrial; Homoaconitate hydratase; EC 4.2.1.36 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
Q92412 homoaconitate hydratase (EC 4.2.1.36) from Aspergillus nidulans (see paper)
    36% identity, 90% coverage of query (94.0 bits)

IPMI2 / Q9ZW84 isopropylmalate isomerase, small subunit (EC 4.2.1.170) from Arabidopsis thaliana (see paper)
LEUD1_ARATH / Q9ZW84 3-isopropylmalate dehydratase small subunit 2; 2-(omega-methylthio)alkylmalate dehydratase small subunit 2; AtLEUD1; Isopropylmalate isomerase 2; Isopropylmalate isomerase small subunit 2; IPMI SSU2; Methylthioalkylmalate isomerase small subunit; MAM-IS; EC 4.2.1.33; EC 4.2.1.170 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9ZW84 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
    32% identity, 98% coverage of query (92.8 bits)

HtyD / K0E2G4 2-(4-hydroxybenzyl)-malate isomerase from Aspergillus rugulosus (see paper)
HTYD_ASPRU / K0E2G4 Aconitase htyD; L-homotyrosine biosynthetic cluster protein D; EC 4.2.1.- from Aspergillus rugulosus (Emericella rugulosa) (see paper)
    36% identity, 96% coverage of query (90.9 bits)

J9VIU5 methanogen homoaconitase (EC 4.2.1.114) from Cryptococcus neoformans var. grubii serotype A (see paper)
    32% identity, 90% coverage of query (88.2 bits)

B1P2N4 homoaconitate hydratase (EC 4.2.1.36) from Penicillium chrysogenum (see paper)
    34% identity, 91% coverage of query (86.3 bits)

ACON3_ASPFU / Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    35% identity, 98% coverage of query (86.3 bits)

IIL1 / Q9ZW85 isopropylmalate isomerase, small subunit (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
LEUD3_ARATH / Q9ZW85 3-isopropylmalate dehydratase small subunit 1; AtLEUD3; Isopropylmalate isomerase small subunit 1; IPMI SSU1; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9ZW85 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
    35% identity, 98% coverage of query (85.5 bits)

LEUD2_ARATH / Q9LYT7 3-isopropylmalate dehydratase small subunit 3; 2-(omega-methylthio)alkylmalate dehydratase small subunit 3; AtLEUD2; Isopropylmalate isomerase 1; Isopropylmalate isomerase small subunit 3; IPMI SSU3; Methylthioalkylmalate isomerase small subunit; MAM-IS; EC 4.2.1.33; EC 4.2.1.170 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9LYT7 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana (see paper)
    36% identity, 98% coverage of query (80.9 bits)

GLOJ_GLAL2 / S3E7P8 3-isopropylmalate dehydratase large subunit gloJ; L-homotyrosine biosynthesis sub-cluster protein gloJ; Pneumocandin biosynthesis cluster protein J; EC 4.2.1.33 from Glarea lozoyensis (strain ATCC 20868 / MF5171) (see 5 papers)
    37% identity, 88% coverage of query (80.9 bits)

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    35% identity, 85% coverage of query (75.9 bits)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    38% identity, 78% coverage of query (70.9 bits)

leu1 / CAB99455.1 3-isopropylmalate dehydratase, partial from Yarrowia lipolytica (see paper)
    38% identity, 74% coverage of query (69.7 bits)

leuD / BAC65258.1 3-isopropylmalate dehydratase small subunit from Burkholderia multivorans (see paper)
    34% identity, 78% coverage of query (69.3 bits)

leuD / Q8F4E5 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see paper)
    34% identity, 71% coverage of query (69.3 bits)

AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
    38% identity, 87% coverage of query (67.8 bits)

LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
    35% identity, 77% coverage of query (65.5 bits)

O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    35% identity, 79% coverage of query (65.5 bits)

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    34% identity, 84% coverage of query (61.6 bits)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis (see paper)
    36% identity, 77% coverage of query (58.5 bits)

P9WK95 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    36% identity, 77% coverage of query (58.5 bits)

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Build an alignment for WP_010876999.1 and 30 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory