Sites on a Tree

 

Searching for up to 100 curated homologs for WP_010877116.1 NCBI__GCF_000008645.1:WP_010877116.1 (287 a.a.)

Found high-coverage hits (≥70%) to 46 curated proteins.

Removed hits that are identical to the query, leaving 45

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7dahC / Q9KSX4 Adenosine triphosphate phosphoribosyltransferase from vibrio cholerae in complex with atp and prpp
    34% identity, 99% coverage of query (164 bits)

HisG / b2019 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli K-12 substr. MG1655 (see paper)
hisG / P60757 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli (strain K12) (see 36 papers)
HIS1_ECOLI / P60757 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Escherichia coli (strain K12) (see 4 papers)
hisG / RF|NP_416523 ATP phosphoribosyltransferase from Escherichia coli K12 (see paper)
    36% identity, 99% coverage of query (162 bits)

HIS1_SALTY / P00499 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    35% identity, 99% coverage of query (159 bits)

4yb6A / Q5HSJ4 Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine (see paper)
    32% identity, 99% coverage of query (158 bits)

Q5HSJ4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see 3 papers)
Q9PM78 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see paper)
    32% identity, 99% coverage of query (158 bits)

4yb7A Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    32% identity, 99% coverage of query (158 bits)

4yb6E Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine
    32% identity, 99% coverage of query (157 bits)

1h3dA / P60757 Structure of the e.Coli atp-phosphoribosyltransferase (see paper)
    35% identity, 99% coverage of query (154 bits)

4yb7C Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    32% identity, 99% coverage of query (154 bits)

1q1kA Structure of atp-phosphoribosyltransferase from e. Coli complexed with pr-atp
    35% identity, 99% coverage of query (154 bits)

DvMF_1963 ATP phosphoribosyltransferase (EC 2.4.2.17) from Desulfovibrio vulgaris Miyazaki F
    33% identity, 99% coverage of query (147 bits)

Q9Z472 ATP phosphoribosyltransferase (EC 2.4.2.17) from Corynebacterium glutamicum (see 2 papers)
    36% identity, 98% coverage of query (144 bits)

DVU0114 ATP phosphoribosyltransferase (EC 2.4.2.17) from Desulfovibrio vulgaris Hildenborough JW710
    34% identity, 99% coverage of query (137 bits)

HIS1 / GB|CAA58751.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Candida albicans (see paper)
    33% identity, 99% coverage of query (133 bits)

his1 / RF|NP_594525.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Schizosaccharomyces pombe (see paper)
his1 / AAA92790.1 ATP phosphoribosyltransferase from Schizosaccharomyces pombe (see paper)
    32% identity, 100% coverage of query (130 bits)

Q56UT2 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    31% identity, 99% coverage of query (127 bits)

6fcaA / Q4FQF7 Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp
    37% identity, 71% coverage of query (126 bits)

Q4FQF7 ATP phosphoribosyltransferase (EC 2.4.2.17) from Psychrobacter arcticus (see 2 papers)
    37% identity, 71% coverage of query (126 bits)

6fd9A Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with amp
    37% identity, 71% coverage of query (126 bits)

6fcwA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with pratp
    37% identity, 71% coverage of query (126 bits)

6fctA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp and atp
    37% identity, 71% coverage of query (126 bits)

6fcyA Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with prpp and adp
    37% identity, 70% coverage of query (126 bits)

G7JFL4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Medicago truncatula (see paper)
    32% identity, 99% coverage of query (124 bits)

6czmE / G7JFL4 Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
    32% identity, 99% coverage of query (123 bits)

1nh8A Atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosis in complex with amp and histidine
    33% identity, 96% coverage of query (123 bits)

Build an alignment

Build an alignment for WP_010877116.1 and 25 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q56UT3 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    29% identity, 99% coverage of query (122 bits)

HIS1_MYCTU / P9WMN1 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
5lhtA / P9WMN1 Atp phosphoribosyltransferase from mycobacterium tuberculosis in complex with the allosteric activator 3-(2-thienyl)-l-alanine (see paper)
    32% identity, 98% coverage of query (121 bits)

AtATP-PRT1 / Q9S762 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1A_ARATH / Q9S762 ATP phosphoribosyltransferase 1, chloroplastic; ATP-PRTase 1; AtATP-PRT1; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9S762 ATP phosphoribosyltransferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
    31% identity, 99% coverage of query (121 bits)

5u99A Transition state analysis of adenosine triphosphate phosphoribosyltransferase
    33% identity, 98% coverage of query (121 bits)

Q56US5 ATP phosphoribosyltransferase (EC 2.4.2.17) from Alyssum montanum (see paper)
    29% identity, 99% coverage of query (120 bits)

AtATP-PRT2 / Q8GSJ1 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1B_ARATH / Q8GSJ1 ATP phosphoribosyltransferase 2, chloroplastic; ATP-PRTase 2; AtATP-PRT2; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    30% identity, 99% coverage of query (117 bits)

AO356_06970 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2C3
    36% identity, 71% coverage of query (109 bits)

Pf6N2E2_3253 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2E2
    36% identity, 71% coverage of query (109 bits)

5ubgA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound phosphoribosyl-atp
    31% identity, 73% coverage of query (109 bits)

6czmF / G7JFL4 Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
    32% identity, 99% coverage of query (108 bits)

5ubiA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound prpp
    31% identity, 72% coverage of query (107 bits)

AO353_05115 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N2E3
    35% identity, 71% coverage of query (104 bits)

PfGW456L13_5001 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens GW456-L13
    35% identity, 71% coverage of query (103 bits)

Pf1N1B4_1067 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas fluorescens FW300-N1B4
    34% identity, 72% coverage of query (103 bits)

5ub9A Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni
    31% identity, 73% coverage of query (103 bits)

PS417_04415 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas simiae WCS417
    34% identity, 72% coverage of query (101 bits)

BPHYT_RS17715 ATP phosphoribosyltransferase (EC 2.4.2.17) from Burkholderia phytofirmans PsJN
    33% identity, 71% coverage of query (100 bits)

PP_0965 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas putida KT2440
    33% identity, 71% coverage of query (100 bits)

AZOBR_RS19500 ATP phosphoribosyltransferase (EC 2.4.2.17) from Azospirillum brasilense Sp245
    34% identity, 70% coverage of query (100 bits)

SMc00917 ATP phosphoribosyltransferase (EC 2.4.2.17) from Sinorhizobium meliloti 1021
    31% identity, 73% coverage of query (95.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory