Searching for up to 100 curated homologs for WP_010877179.1 NCBI__GCF_000008645.1:WP_010877179.1 (442 a.a.)
Found high-coverage hits (≥70%) to 78 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
8oooA Glutamine synthetase from methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and mgatp at 2.15 a resolution (see paper)
56% identity, 99% coverage of query (522 bits)
8ooqB Glutamine synthetase from Methanothermococcus thermolithotrophicus
56% identity, 99% coverage of query (522 bits)
8ufjB / Q8PY99 8ufjB (see paper)
55% identity, 98% coverage of query (495 bits)
GLNA1_METMA / Q8PY99 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
Q8PY99 glutamine synthetase (EC 6.3.1.2) from Methanosarcina mazei (see paper)
54% identity, 98% coverage of query (494 bits)
GLNA_METJA / Q60182 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q60182 glutamine synthetase (EC 6.3.1.2) from Methanocaldococcus jannaschii (see paper)
55% identity, 100% coverage of query (494 bits)
8tfkA Glutamine synthetase
54% identity, 98% coverage of query (494 bits)
8ooxB / A0A832VZP6 8ooxB (see paper)
54% identity, 99% coverage of query (481 bits)
P36205 glutamine synthetase (EC 6.3.1.2) from Thermotoga maritima (see paper)
54% identity, 99% coverage of query (472 bits)
GLNA3_HALMT / I3R176 Glutamine synthetase 3; GS3; Glutamate--ammonia ligase; EC 6.3.1.2 from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
B8ZJH0 glutamine synthetase (EC 6.3.1.2) from Haloferax mediterranei (see paper)
53% identity, 100% coverage of query (472 bits)
8oozA Glutamine synthetase
54% identity, 99% coverage of query (469 bits)
7tdvC / E3VXC2 7tdvC (see paper)
52% identity, 97% coverage of query (458 bits)
4lnkA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of gs-glutamate-amppcp complex
52% identity, 97% coverage of query (457 bits)
4lniA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
52% identity, 97% coverage of query (457 bits)
4s0rD / P12425 Structure of gs-tnra complex (see paper)
52% identity, 97% coverage of query (456 bits)
GLN1A_BACSU / P12425 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Bacillus subtilis (strain 168) (see 9 papers)
P12425 glutamine synthetase (EC 6.3.1.2) from Bacillus subtilis (see 2 papers)
52% identity, 97% coverage of query (456 bits)
7tfaB / A0A0F0G8G2 7tfaB (see paper)
52% identity, 98% coverage of query (456 bits)
GLNA_THET8 / Q5SIP0 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
53% identity, 98% coverage of query (456 bits)
7tdpA Structure of paenibacillus polymyxa gs bound to met-sox-p-adp (transition state complex) to 1.98 angstom
52% identity, 98% coverage of query (454 bits)
7tf6A Glutamine synthetase
52% identity, 97% coverage of query (452 bits)
7tf9S / A0A5D5GA79 L. Monocytogenes gs(14)-q-glnr peptide (see paper)
51% identity, 97% coverage of query (438 bits)
7tenA Glutamine synthetase
51% identity, 97% coverage of query (438 bits)
Q0E5H7 glutamine synthetase (EC 6.3.1.2) from Halobacillus halophilus (see paper)
49% identity, 96% coverage of query (436 bits)
C4L2T5 glutamine synthetase (EC 6.3.1.2) from Exiguobacterium sp. (see paper)
49% identity, 99% coverage of query (436 bits)
P36687 glutamine synthetase (EC 6.3.1.2) from Pyrococcus woesei (see paper)
51% identity, 96% coverage of query (416 bits)
GLNA_THEKO / O08467 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
O08467 glutamine synthetase (EC 6.3.1.2) from Pyrococcus sp. (see paper)
47% identity, 96% coverage of query (398 bits)
GLNA2_STRCO / Q9RDS6 Gamma-glutamylpolyamine synthetase GlnA2; EC 6.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 3 papers)
45% identity, 98% coverage of query (375 bits)
P64246 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis variant bovis (see paper)
44% identity, 98% coverage of query (360 bits)
P9WN37 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
44% identity, 98% coverage of query (360 bits)
A0R083 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
43% identity, 98% coverage of query (357 bits)
GLNA_SULAC / Q9HH09 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q9HH09 glutamine synthetase (EC 6.3.1.2) from Sulfolobus acidocaldarius (see paper)
41% identity, 97% coverage of query (327 bits)
GLNA_ARCFU / O29313 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
O29313 glutamine synthetase (EC 6.3.1.2) from Archaeoglobus fulgidus (see paper)
41% identity, 100% coverage of query (324 bits)
gmas / A9ZPH9 glutamate--methylamine ligase monomer (EC 6.3.4.12; EC 6.3.1.6) from Methylovorus mays (see 2 papers)
GMAS_METMY / A9ZPH9 Glutamate--methylamine ligase; Gamma-glutamylmethylamide synthetase; GMAS; Glutamate--ethylamine ligase; N(5)-ethyl-L-glutamine synthetase; Theanine synthetase; EC 6.3.4.12; EC 6.3.1.6 from Methylovorus mays (see 2 papers)
A9ZPH9 glutamate-methylamine ligase (EC 6.3.4.12) from Methylovorus mays (see paper)
41% identity, 96% coverage of query (314 bits)
1f1hA / P0A1P6 Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions (see paper)
40% identity, 98% coverage of query (314 bits)
1fpyA Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor phosphinothricin
40% identity, 98% coverage of query (314 bits)
GLN1B_SALTY / P0A1P6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
P0A1P6 glutamine synthetase (EC 6.3.1.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
glnA glutamate--ammonia ligase; EC 6.3.1.2 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
40% identity, 98% coverage of query (311 bits)
glnA / P0A9C5 glutamine synthetase (EC 6.3.1.2) from Escherichia coli (strain K12) (see 59 papers)
glnA glutamate--ammonia ligase; EC 6.3.1.2 from Escherichia coli K12 (see paper)
adenylyl-[glutamine synthetase] / ECOCYC|ADENYLYL-GS glutamine synthetase from Escherichia coli K12 (see paper)
40% identity, 98% coverage of query (310 bits)
P0A9C5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Escherichia coli (strain K12)
40% identity, 98% coverage of query (310 bits)
glnA / Q31L83 glutamine synthetase, type I from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (see paper)
39% identity, 100% coverage of query (307 bits)
GLN1B_SYNY3 / P77961 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P77961 glutamine synthetase (EC 6.3.1.2) from Synechocystis sp. (see paper)
39% identity, 100% coverage of query (301 bits)
glnA / CAA78366.1 glutamine synthetase from Synechococcus sp. PCC 7002 (see paper)
39% identity, 100% coverage of query (300 bits)
GMAS_METUF / F5RH07 Glutamate--methylamine ligase; Gamma-glutamylmethylamide synthetase; GMAS; EC 6.3.4.12 from Methyloversatilis universalis (strain ATCC BAA-1314 / DSM 25237 / JCM 13912 / CCUG 52030 / FAM5) (see paper)
40% identity, 98% coverage of query (299 bits)
glnA / CAA48234.1 glutamate--ammonia ligase from Proteus vulgaris (see paper)
41% identity, 89% coverage of query (296 bits)
Reut_A2057 / Q46ZL2 3-(hydroxyamino)phenol mutase (EC 5.4.4.3) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
3HAPM_CUPPJ / Q46ZL2 3-hydroxylaminophenol mutase; 3HAP mutase; 3-(hydroxyamino)phenol mutase; EC 5.4.4.3 from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator (strain JMP 134)) (see paper)
39% identity, 100% coverage of query (295 bits)
O85177 glutamine synthetase (EC 6.3.1.2) from Amycolatopsis mediterranei (see paper)
40% identity, 100% coverage of query (294 bits)
3ng0A / P77961 Crystal structure of glutamine synthetase from synechocystis sp. Pcc 6803
39% identity, 98% coverage of query (293 bits)
GLN1B_NOSS1 / P00964 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
39% identity, 98% coverage of query (293 bits)
GLN1B_PSETA / Q3V5W6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Pseudomonas taetrolens (see 2 papers)
40% identity, 96% coverage of query (288 bits)
A0R079 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
39% identity, 100% coverage of query (288 bits)
Q9RHZ1 glutamine synthetase (EC 6.3.1.2) from Trichormus azollae (see paper)
38% identity, 98% coverage of query (287 bits)
GLN1B_STRCO / P15106 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
P15106 glutamine synthetase (EC 6.3.1.2) from Streptomyces coelicolor (see paper)
40% identity, 100% coverage of query (285 bits)
1htoA / P9WN39 Crystallographic structure of a relaxed glutamine synthetase from mycobacterium tuberculosis (see paper)
39% identity, 96% coverage of query (283 bits)
GLN1B_MYCBO / P0A591 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see 2 papers)
GLN1B_MYCTU / P9WN39 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 9 papers)
P0A591 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis variant bovis (see paper)
P9WN39 glutamine synthetase (EC 6.3.1.2) from Mycobacterium tuberculosis (see 12 papers)
39% identity, 96% coverage of query (283 bits)
2whiA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a purine analogue inhibitor and l-methionine-s- sulfoximine phosphate.
39% identity, 96% coverage of query (283 bits)
4acfA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with imidazopyridine inhibitor ((4-(6-bromo-3- (butylamino)imidazo(1,2-a)pyridin-2-yl)phenoxy) acetic acid) and l- methionine-s-sulfoximine phosphate.
39% identity, 96% coverage of query (283 bits)
3zxvA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl)pyridin-2-amine) and l- methionine-s-sulfoximine phosphate
39% identity, 96% coverage of query (283 bits)
3zxrA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1h-imidazol-4-yl)quinoline) and l-methionine-s- sulfoximine phosphate.
39% identity, 96% coverage of query (283 bits)
2bvcA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic
39% identity, 96% coverage of query (283 bits)
2lgsA Feedback inhibition of fully unadenylylated glutamine synthetase from salmonella typhimurium by glycine, alanine, and serine
38% identity, 98% coverage of query (279 bits)
1lgrA / P0A1P6 Interactions of nucleotides with fully unadenylylated glutamine synthetase from salmonella typhimurium (see paper)
38% identity, 98% coverage of query (279 bits)
2wgsA Crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a purine analogue inhibitor.
37% identity, 96% coverage of query (269 bits)
4xycA Nanomolar inhibitors of mycobacterium tuberculosis glutamine synthetase 1: synthesis, biological evaluation and x-ray crystallographic studies
37% identity, 96% coverage of query (266 bits)
5zlpL Crystal structure of glutamine synthetase from helicobacter pylori
38% identity, 88% coverage of query (260 bits)
5zlpA Crystal structure of glutamine synthetase from helicobacter pylori
38% identity, 88% coverage of query (260 bits)
5zlpJ / P94845 Crystal structure of glutamine synthetase from helicobacter pylori (see paper)
38% identity, 88% coverage of query (260 bits)
4s17A / A1A1Z1 The crystal structure of glutamine synthetase from bifidobacterium adolescentis atcc 15703
36% identity, 98% coverage of query (256 bits)
7cquA Gmas/adp/metsox-p complex
34% identity, 97% coverage of query (215 bits)
7cqqA Gmas in complex with amppnp and metsox
34% identity, 97% coverage of query (215 bits)
7cqnA Gmas in complex with amppcp
34% identity, 97% coverage of query (215 bits)
7cqwA / A0A369R1N0 Gmas/adp complex-conformation 1 (see paper)
34% identity, 97% coverage of query (215 bits)
Build an alignment for WP_010877179.1 and 69 homologs with ≥ 30% identity
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8wwvA Glutamine synthetase
29% identity, 96% coverage of query (189 bits)
8wwuB / A0A7Y1Q2L1 8wwuB
29% identity, 96% coverage of query (189 bits)
5dm3A / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
30% identity, 85% coverage of query (149 bits)
5dm3C / Q1QZR8 Crystal structure of glutamine synthetase from chromohalobacter salexigens dsm 3043(csal_0679, target efi-550015) with bound adp
30% identity, 83% coverage of query (147 bits)
4hppA / Q9HT65 Crystal structure of novel glutamine synthase homolog (see paper)
26% identity, 92% coverage of query (130 bits)
GLN13_ARATH / Q9LVI8 Glutamine synthetase cytosolic isozyme 1-3; GS1; Glutamate--ammonia ligase GLN1;3; GLN1;3; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LVI8 glutamine synthetase (EC 6.3.1.2) from Arabidopsis thaliana (see 2 papers)
23% identity, 81% coverage of query (59.3 bits)
2d3cA Crystal structure of the maize glutamine synthetase complexed with adp and phosphinothricin phosphate
23% identity, 80% coverage of query (56.6 bits)
2d3bA Crystal structure of the maize glutamine synthetase complexed with amppnp and methionine sulfoximine
23% identity, 80% coverage of query (56.6 bits)
2d3aA / P38561 Crystal structure of the maize glutamine synthetase complexed with adp and methionine sulfoximine phosphate (see paper)
23% identity, 80% coverage of query (56.6 bits)
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Lawrence Berkeley National Laboratory