Searching for up to 100 curated homologs for WP_010963351.1 NCBI__GCF_000008765.1:WP_010963351.1 (360 a.a.)
Found high-coverage hits (≥70%) to 39 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q4WWR8 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Aspergillus fumigatus (see paper)
41% identity, 99% coverage of query (258 bits)
asd / Q57658 aspartate-semialdehyde dehydrogenase monomer (EC 1.2.1.11) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
DHAS_METJA / Q57658 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
42% identity, 96% coverage of query (247 bits)
1ys4A / Q57658 Structure of aspartate-semialdehyde dehydrogenase from methanococcus jannaschii (see paper)
42% identity, 96% coverage of query (247 bits)
P78780 Probable aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
38% identity, 98% coverage of query (236 bits)
3hskA / Q5ALM0 Crystal structure of aspartate semialdehyde dehydrogenase with NADP from candida albicans (see paper)
37% identity, 98% coverage of query (233 bits)
4zicC / A0A140UHG6 Crystal structure of aspartate semialdehyde dehydrogenase with NADP from trichophyton rubrum (see paper)
38% identity, 99% coverage of query (230 bits)
Q5KPK7 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Cryptococcus neoformans var. neoformans (see paper)
37% identity, 99% coverage of query (229 bits)
DHAS_YEAST / P13663 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
38% identity, 96% coverage of query (229 bits)
C5GC63 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Blastomyces dermatitidis (see paper)
37% identity, 99% coverage of query (225 bits)
6c8wA Crystal structure of aspartate semialdehyde dehydrogenase with NADP from blastomyces dermatitidis (see paper)
37% identity, 99% coverage of query (224 bits)
6c85A Crystal structure of aspartate semialdehyde dehydrogenase from blastomyces dermatitidis with p-benzoquinone
37% identity, 99% coverage of query (223 bits)
Msed_0709 / A4YEN2 succinyl-CoA reductase (NADPH) subunit (EC 1.2.1.75; EC 1.2.1.76) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 3 papers)
MCR_METS5 / A4YEN2 Malonyl CoA reductase (NADP); NADP-dependent malonyl CoA reductase; EC 1.2.1.75 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
35% identity, 99% coverage of query (186 bits)
4dpkA / Q96YK1 Structure of malonyl-coenzyme a reductase from crenarchaeota (see paper)
33% identity, 98% coverage of query (167 bits)
mcr / Q96YK1 malonyl-CoA reductase subunit (EC 1.2.1.75) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see paper)
MCR_SULTO / Q96YK1 Malonyl-CoA reductase; EC 1.2.1.75 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96YK1 malonyl-CoA reductase (malonate semialdehyde-forming) (EC 1.2.1.75) from Sulfurisphaera tokodaii (see 3 papers)
33% identity, 98% coverage of query (167 bits)
4dpmA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with coa
33% identity, 98% coverage of query (167 bits)
4dplA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with NADP
33% identity, 98% coverage of query (167 bits)
Build an alignment for WP_010963351.1 and 16 homologs with ≥ 30% identity
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8jusA / A0AAF0BGE9 Crystal structure of aspartate semialdehyde dehydrogenase from porphyromonas gingivalis complexed with 2',5'adenosine diphosphate
26% identity, 98% coverage of query (78.6 bits)
asd / Q04797 aspartate semialdehyde dehydrogenase subunit (EC 1.2.1.11) from Bacillus subtilis (strain 168) (see paper)
25% identity, 97% coverage of query (76.6 bits)
Q04797 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Bacillus subtilis (strain 168)
25% identity, 97% coverage of query (76.6 bits)
DHAS2_VIBCH / P23247 Aspartate-semialdehyde dehydrogenase 2; ASA dehydrogenase 2; ASADH 2; Aspartate-beta-semialdehyde dehydrogenase 2; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
26% identity, 97% coverage of query (68.9 bits)
2r00C / P23247 Crystal structure of aspartate semialdehyde dehydrogenase ii complexed with asa from vibrio cholerae (see paper)
26% identity, 97% coverage of query (68.6 bits)
AT1G14810 / Q8VYI4 aspartate semialdehyde dehydrogenase (EC 1.2.1.11) from Arabidopsis thaliana (see paper)
27% identity, 96% coverage of query (59.3 bits)
4r5hA Crystal structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide-adenine-dinucleotide-phosphate and 3-carboxy-propenyl- phthalic acid
26% identity, 98% coverage of query (57.8 bits)
4r4jA Crystal structure of complex sp_asadh with 3-carboxypropyl-phthalic acid and nicotinamide adenine dinucleotide phosphate
26% identity, 98% coverage of query (57.8 bits)
3pyxB Crystals structure of aspartate beta-semialdehyde dehydrogenase complex with NADP and 2-aminoterephthalate
26% identity, 98% coverage of query (57.8 bits)
4r51A Crystal complex structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide adenine dinucleotide phosphate and phthalic acid
26% identity, 98% coverage of query (57.8 bits)
3tz6A / P9WNX5 Crystal structure of aspartate semialdehyde dehydrogenase complexed with inhibitor smcs (cys) and phosphate from mycobacterium tuberculosis h37rv (see paper)
24% identity, 76% coverage of query (57.8 bits)
3q11A Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with NADP and aspartyl beta- difluorophosphonate
26% identity, 98% coverage of query (57.8 bits)
3pylC Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with d-2,3-diaminopropionate (see paper)
26% identity, 98% coverage of query (57.8 bits)
4r54A Complex crystal structure of sp-aspartate-semialdehyde-dehydrogenase with 3-carboxy-ethyl-phthalic acid
26% identity, 98% coverage of query (57.8 bits)
4r41A Complex crystal structure of 4-nitro-2-phosphono-benzoic acid with sp- aspartate-semialdehyde dehydrogenase and nicotinamide-dinucleotide
26% identity, 98% coverage of query (57.8 bits)
4r3nA Crystal structure of the ternary complex of sp-asadh with NADP and 1, 2,3-benzenetricarboxylic acid
26% identity, 98% coverage of query (57.8 bits)
3q1lA Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with cysteamine bound covalently to cys 128
26% identity, 98% coverage of query (57.8 bits)
3pwsA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
26% identity, 98% coverage of query (57.8 bits)
3pwkA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
26% identity, 98% coverage of query (57.8 bits)
2gz3A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP and aspartate- semialdehyde
26% identity, 98% coverage of query (57.8 bits)
2gz2A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with 2',5'-adp
26% identity, 98% coverage of query (57.8 bits)
2gz1A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP
26% identity, 98% coverage of query (57.8 bits)
Q8KQ27 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Streptomyces clavuligerus (see paper)
26% identity, 73% coverage of query (55.5 bits)
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