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Searching for up to 100 curated homologs for WP_010964290.1 NCBI__GCF_000008765.1:WP_010964290.1 (334 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
    56% identity, 99% coverage of query (388 bits)

IDH-V / Q945K7 NAD+-dependent isocitrate dehydrogenase catalytic subunit (EC 1.1.1.286) from Arabidopsis thaliana (see 3 papers)
IDH5_ARATH / Q945K7 Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; IDH-V; Isocitric dehydrogenase 5; NAD(+)-specific ICDH 5; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    53% identity, 99% coverage of query (363 bits)

IDH3A_MOUSE / Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Mus musculus (Mouse) (see paper)
Q9D6R2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Mus musculus (see paper)
    52% identity, 99% coverage of query (358 bits)

IDH3A_BOVIN / P41563 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitrate dehydrogenase subunits 3/4; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Bos taurus (Bovine) (see paper)
    52% identity, 99% coverage of query (357 bits)

IDH3A_PIG / P56471 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Sus scrofa (Pig) (see paper)
    52% identity, 99% coverage of query (357 bits)

6kdeA / P50213 Crystal structure of the alpha beta heterodimer of human idh3 in complex with ca(2+) (see paper)
    52% identity, 99% coverage of query (356 bits)

IDH3A / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3A_HUMAN / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Homo sapiens (Human) (see 5 papers)
P50213 isocitrate dehydrogenase (NAD+) (subunit 2/2) (EC 1.1.1.41) from Homo sapiens (see paper)
    52% identity, 99% coverage of query (356 bits)

6kdyA Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
    52% identity, 99% coverage of query (356 bits)

IDH3A_RAT / Q99NA5 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Rattus norvegicus (Rat) (see paper)
Q99NA5 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rattus norvegicus (see paper)
    51% identity, 99% coverage of query (351 bits)

5yvtA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+) and nadh
    52% identity, 99% coverage of query (349 bits)

IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    52% identity, 98% coverage of query (348 bits)

8grdA Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
    52% identity, 99% coverage of query (345 bits)

6l59A Crystal structure of the alpha gamma heterodimer of human idh3 in complex with cit, mg and atp binding at allosteric site and mg, atp binding at active site.
    51% identity, 99% coverage of query (345 bits)

5greA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+), citrate and adp
    51% identity, 99% coverage of query (345 bits)

IDH3A_CAEEL / Q93714 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Caenorhabditis elegans (see paper)
    50% identity, 98% coverage of query (342 bits)

G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
    52% identity, 99% coverage of query (342 bits)

6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
    50% identity, 99% coverage of query (330 bits)

P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
    48% identity, 98% coverage of query (320 bits)

2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
    48% identity, 98% coverage of query (320 bits)

IDH2 / P28241 isocitrate dehydrogenase [NAD] β subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH2_YEAST / P28241 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P28241 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
    48% identity, 99% coverage of query (318 bits)

IDH2_SCHPO / Q9USP8 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
    46% identity, 99% coverage of query (317 bits)

idh2 / RF|NP_595203.1 isocitrate dehydrogenase (NAD+) subunit 2; EC 1.1.1.41 from Schizosaccharomyces pombe (see 2 papers)
    46% identity, 99% coverage of query (317 bits)

G1APK2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
    48% identity, 99% coverage of query (313 bits)

3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
    47% identity, 99% coverage of query (307 bits)

IDH-II / P93032 NAD+-dependent isocitrate dehydrogenase regulatory subunit (EC 1.1.1.286) from Arabidopsis thaliana (see paper)
IDH2_ARATH / P93032 Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; IDH-II; Isocitric dehydrogenase 2; NAD(+)-specific ICDH 2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P93032 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    46% identity, 99% coverage of query (303 bits)

hdh / BAD06515.1 homoisocitrate dehydrogenase, partial from Deinococcus radiodurans (see paper)
    49% identity, 99% coverage of query (301 bits)

IDH1_ARATH / Q8LFC0 Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; IDH-I; Isocitric dehydrogenase 1; NAD(+)-specific ICDH 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LFC0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    46% identity, 98% coverage of query (299 bits)

LEU3_SULTO / P50455 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
P50455 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfurisphaera tokodaii (see 3 papers)
    49% identity, 97% coverage of query (298 bits)

IDH3_ARATH / O81796 Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; IDH-III; Isocitric dehydrogenase 3; NAD(+)-specific ICDH 3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O81796 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    46% identity, 98% coverage of query (298 bits)

MJ0720 / Q58130 3-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
LEU3_METJA / Q58130 3-isopropylmalate/3-methylmalate dehydrogenase; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.85; EC 1.1.1.n5; EC 1.1.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    49% identity, 99% coverage of query (294 bits)

hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
    47% identity, 99% coverage of query (287 bits)

3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
    47% identity, 99% coverage of query (286 bits)

4yb4A Crystal structure of homoisocitrate dehydrogenase from thermus thermophilus in complex with homoisocitrate, magnesium ion (ii) and nadh
    47% identity, 99% coverage of query (286 bits)

3asjB Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
    47% identity, 99% coverage of query (286 bits)

IDH1_SCHPO / O13696 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
idh1 / RF|NP_594397.1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1; EC 1.1.1.41 from Schizosaccharomyces pombe (see 3 papers)
    46% identity, 99% coverage of query (280 bits)

3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
    44% identity, 99% coverage of query (280 bits)

3blwA Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits
    44% identity, 99% coverage of query (280 bits)

5yvtB Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+) and nadh
    45% identity, 99% coverage of query (280 bits)

6l57B Crystal structure of the alpha gamma heterodimer of human idh3 in complex with cit , mg and atp binding at allosteric site.
    45% identity, 99% coverage of query (280 bits)

IDH3G / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3G_HUMAN / P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Isocitric dehydrogenase subunit gamma; NAD(+)-specific ICDH subunit gamma from Homo sapiens (Human) (see 3 papers)
P51553 isocitrate dehydrogenase (NAD+) (subunit 1/3) (EC 1.1.1.41) from Homo sapiens (see 4 papers)
    45% identity, 99% coverage of query (279 bits)

IDH1 / P28834 isocitrate dehydrogenase [NAD] α subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH1_YEAST / P28834 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P28834 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
    44% identity, 99% coverage of query (278 bits)

6kdyD / O43837 Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD. (see paper)
    46% identity, 98% coverage of query (278 bits)

6kdyF Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
    46% identity, 98% coverage of query (278 bits)

5grfB / P51553 Crystal structure of the alpha gamma mutant (gamma-k151a) of human idh3 in complex with mg(2+), citrate and adp (see paper)
    44% identity, 99% coverage of query (277 bits)

4y1pB / Q4JB37 Crystal structure of 3-isopropylmalate dehydrogenase (saci_0600) from sulfolobus acidocaldarius complex with 3-isopropylmalate and mg2+ (see paper)
    46% identity, 98% coverage of query (276 bits)

Q4JB37 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfolobus acidocaldarius (see paper)
    46% identity, 98% coverage of query (276 bits)

aksF / Q58991 NAD-dependent threo-isocitrate dehydrogenase (EC 1.1.1.87) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AKSF_METJA / Q58991 Homoisocitrate dehydrogenase; HICDH; Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase; Isohomocitrate dehydrogenase; IHDH; NAD-dependent threo-isohomocitrate dehydrogenase; EC 1.1.1.87; EC 1.1.1.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58991 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii (see paper)
    45% identity, 98% coverage of query (276 bits)

IDH3B / O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3B_HUMAN / O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Isocitric dehydrogenase subunit beta; NAD(+)-specific ICDH subunit beta from Homo sapiens (Human) (see 3 papers)
O43837 isocitrate dehydrogenase (NAD+) (subunit 1/2) (EC 1.1.1.41) from Homo sapiens (see paper)
    46% identity, 98% coverage of query (274 bits)

8grdB Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
    45% identity, 98% coverage of query (272 bits)

IDHG2_MOUSE / Q8BPC6 Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial; Isocitric dehydrogenase subunit gamma 2; NAD(+)-specific ICDH subunit gamma 2 from Mus musculus (Mouse) (see paper)
    43% identity, 96% coverage of query (267 bits)

2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
    41% identity, 99% coverage of query (265 bits)

LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
    45% identity, 100% coverage of query (264 bits)

icd / Q5UXA4 isocitrate dehydrogenase, NADP (EC 1.1.1.42) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see 4 papers)
    41% identity, 99% coverage of query (259 bits)

Q8U488 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Pyrococcus furiosus (see 2 papers)
    44% identity, 98% coverage of query (259 bits)

lysB putative homoisocitrate dehydrogenase from Emericella nidulans (see paper)
    44% identity, 98% coverage of query (256 bits)

icdh / CAC80860.2 NADP-isocitrate dehydrogenase from Haloferax volcanii (see paper)
    40% identity, 99% coverage of query (255 bits)

IDH_HALVD / D4GU92 Isocitrate dehydrogenase [NADP]; IDH; ICDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    40% identity, 99% coverage of query (255 bits)

Q9HLV8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermoplasma acidophilum (see paper)
    39% identity, 99% coverage of query (252 bits)

LYS12_SCHPO / O14104 Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.87 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    41% identity, 98% coverage of query (246 bits)

3ty3A / O14104 Crystal structure of homoisocitrate dehydrogenase from schizosaccharomyces pombe bound to glycyl-glycyl-glycine (see paper)
    41% identity, 98% coverage of query (245 bits)

Q1XIQ8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Colwellia psychrerythraea (see paper)
    42% identity, 88% coverage of query (245 bits)

icd / BAA03135.1 isocitrate dehydrogenase isozyme IDH-I from Colwellia maris (see paper)
    41% identity, 87% coverage of query (238 bits)

Q1GZD1 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Methylobacillus flagellatus (see paper)
    38% identity, 98% coverage of query (237 bits)

1isoA Isocitrate dehydrogenase: structure of an engineered NADP+--> NAD+ specificity-reversal mutant
    38% identity, 99% coverage of query (237 bits)

IDH_PSEAB / Q02NB5 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    40% identity, 89% coverage of query (236 bits)

2e5mA / Q96YK6 Crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain 7 (see paper)
    40% identity, 98% coverage of query (236 bits)

IDH_BACSU / P39126 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Bacillus subtilis (strain 168) (see paper)
icd / GB|CAB14873.1 isocitrate dehydrogenase; EC 1.1.1.42 from Bacillus subtilis (see 2 papers)
    37% identity, 99% coverage of query (236 bits)

1tyoA / Q9YE81 Isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in complex with etheno-NADP (see paper)
    38% identity, 94% coverage of query (233 bits)

Q9YE81 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Aeropyrum pernix (see 4 papers)
    38% identity, 94% coverage of query (233 bits)

6c0eA / Q5ZXB6 Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
    36% identity, 99% coverage of query (233 bits)

IcdE / b1136 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
icd / P08200 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli (strain K12) (see 3 papers)
IDH_ECOLI / P08200 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Escherichia coli (strain K12) (see 7 papers)
P08200 [Isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) from Escherichia coli (see paper)
4aj3A / P08200 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and NADP - the pseudo-michaelis complex (see paper)
    37% identity, 99% coverage of query (230 bits)

1bl5A Isocitrate dehydrogenase from e. Coli single turnover laue structure of rate-limited product complex, 10 msec time resolution
    37% identity, 99% coverage of query (230 bits)

1ai3A Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences
    37% identity, 99% coverage of query (230 bits)

1ai2A Isocitrate dehydrogenase complexed with isocitrate, NADP+, and calcium (flash-cooled)
    37% identity, 99% coverage of query (230 bits)

4ajaA 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp
    37% identity, 99% coverage of query (230 bits)

Q4J6C9 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Sulfolobus acidocaldarius (see paper)
    38% identity, 93% coverage of query (229 bits)

IDH_COXBU / Q9ZH99 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    37% identity, 98% coverage of query (229 bits)

1hj6A Isocitrate dehydrogenase s113e mutant complexed with isopropylmalate, NADP+ and magnesium (flash-cooled)
    37% identity, 99% coverage of query (228 bits)

1idcA Isocitrate dehydrogenase from e.Coli (mutant k230m), steady-state intermediate complex determined by laue crystallography
    37% identity, 99% coverage of query (228 bits)

4ajcA 3d structure of e. Coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate
    37% identity, 99% coverage of query (228 bits)

1cw4A Crystal structure of k230m isocitrate dehydrogenase in complex with alpha-ketoglutarate
    37% identity, 99% coverage of query (228 bits)

1cw1A Crystal structure of isocitrate dehydrogenase mutant k230m bound to isocitrate and mn2+
    37% identity, 99% coverage of query (228 bits)

P96318 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Caldococcus noboribetus (see 2 papers)
    39% identity, 94% coverage of query (227 bits)

Q5JFV8 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Thermococcus kodakarensis (see paper)
    41% identity, 99% coverage of query (227 bits)

5hn4A / Q5JFV8 Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and homoisocitrate (see paper)
    41% identity, 99% coverage of query (227 bits)

5hn6A Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and 3-isopropylmalate
    41% identity, 99% coverage of query (227 bits)

LEU3_THET8 / Q5SIY4 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 4 papers)
Q5SIY4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 12 papers)
    38% identity, 98% coverage of query (226 bits)

P61494 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 2 papers)
    38% identity, 98% coverage of query (226 bits)

P24098 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus aquaticus (see paper)
    38% identity, 98% coverage of query (226 bits)

2y41A Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with ipm and mn
    38% identity, 98% coverage of query (226 bits)

2ztwA Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
    38% identity, 98% coverage of query (226 bits)

1groA Regulatory and catalytic mechanisms in escherichia coli isocitrate dehydrogenase: multiple roles for n115
    37% identity, 99% coverage of query (226 bits)

2d4vA / Q8GAX0 Crystal structure of NAD dependent isocitrate dehydrogenase from acidithiobacillus thiooxidans (see paper)
    36% identity, 98% coverage of query (225 bits)

2y42D / Q5SIY4 Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with nadh and mn (see paper)
    38% identity, 98% coverage of query (225 bits)

1xkdA Ternary complex of isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix
    38% identity, 94% coverage of query (221 bits)

3flkA / Q51945 Crystal structure of tartrate dehydrogenase from pseudomonas putida in complex with nadh, oxalate and metal ion (see paper)
    35% identity, 96% coverage of query (199 bits)

LEU3_SALTY / P37412 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
P37412 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
1cnzA / P37412 3-isopropylmalate dehydrogenase (ipmdh) from salmonella typhimurium (see paper)
    36% identity, 100% coverage of query (197 bits)

6xxyA / P43860 Crystal structure of haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with o-isobutenyl oxalylhydroxamate. (see paper)
    37% identity, 96% coverage of query (190 bits)

2g4oA / P9WKK9 Anomalous substructure of 3-isopropylmalate dehydrogenase (see paper)
    36% identity, 93% coverage of query (186 bits)

LEU32_ARATH / P93832 3-isopropylmalate dehydrogenase 2, chloroplastic; 3-IPM-DH 2; AtIMDH2; AtIMDH3; IMDH 2; Beta-IPM dehydrogenase 2; Isopropylmalate dehydrogenase 2; AtIMD2; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P93832 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
    35% identity, 100% coverage of query (182 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory