Searching for up to 100 curated homologs for WP_010966303.1 NCBI__GCF_000008765.1:WP_010966303.1 (219 a.a.)
Found high-coverage hits (≥70%) to 70 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6m1xC Crystal structure of phosphoserine phosphatase in complex with 3- phosphoglyceric acid from entamoeba histolytica
41% identity, 91% coverage of query (144 bits)
5zr2C / N9V397 Crystal structure of phosphoserine phosphatase mutant (h9a) from entamoeba histolytica in complex with phosphoserine (see paper)
40% identity, 91% coverage of query (141 bits)
PSPA_HYDTT / D3DFG8 Phosphoserine phosphatase 1; PSP 1; PSPase 1; Metal-independent phosphoserine phosphatase 1; iPSP1; O-phosphoserine phosphohydrolase 1; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFG8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see 3 papers)
34% identity, 93% coverage of query (114 bits)
4ij6A / D3DFG8 Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
33% identity, 93% coverage of query (110 bits)
1h2eA / Q9ALU0 Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
34% identity, 92% coverage of query (103 bits)
1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate
34% identity, 92% coverage of query (103 bits)
SERCL_ARATH / F4KI56 Metal-independent phosphoserine phosphatase; iPSP; Phosphoglycerate mutase-like protein 3; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 91% coverage of query (100 bits)
cobC / D1BMI5 adenosylcobamide phosphatase (EC 3.1.3.73) from Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3) (see paper)
30% identity, 91% coverage of query (97.8 bits)
CA1P_ARATH / Q9FNJ9 Probable 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 83% coverage of query (91.7 bits)
PSPB_HYDTT / D3DFP8 Putative phosphoserine phosphatase 2; PSP 2; PSPase 2; Metal-independent phosphoserine phosphatase 2; iPSP2; O-phosphoserine phosphohydrolase 2; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFP8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see paper)
31% identity, 90% coverage of query (90.5 bits)
CA1P_WHEAT / W5EP13 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Triticum aestivum (Wheat) (see paper)
30% identity, 91% coverage of query (89.7 bits)
YtjC / b4395 putative phosphatase from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gpmB / RF|NP_418812 PGAM from Escherichia coli K12 (see paper)
33% identity, 90% coverage of query (88.6 bits)
PHOE_BACSU / O07617 Uncharacterized phosphatase PhoE; EC 3.1.3.- from Bacillus subtilis (strain 168) (see 2 papers)
32% identity, 91% coverage of query (85.9 bits)
PhpB / b0638 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
cobC / P52086 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli (strain K12) (see 2 papers)
33% identity, 75% coverage of query (85.1 bits)
Q2YJN6 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Brucella abortus (see paper)
32% identity, 90% coverage of query (82.8 bits)
RNHPH_MYCTU / P9WLH5 Bifunctional protein Rv2228c; EC 3.1.26.4; EC 3.1.3.73 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WLH5 ribonuclease H (EC 3.1.26.4); adenosylcobalamin/alpha-ribazole phosphatase (EC 3.1.3.73) from Mycobacterium tuberculosis (see paper)
31% identity, 91% coverage of query (80.9 bits)
cobC / P39701 adenosylcobalamin/α-ribazole phosphatase (EC 3.1.3.73) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
COBC_SALTY / P39701 Adenosylcobalamin/alpha-ribazole phosphatase; Adenosylcobalamin phosphatase; Alpha-ribazole-5'-phosphate phosphatase; EC 3.1.3.73 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
P39701 adenosylcobalamin/alpha-ribazole phosphatase (EC 3.1.3.73) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
cobC / RF|NP_459635.1 alpha-ribazole phosphatase; EC 3.1.3.73 from Salmonella typhimurium LT2 (see 2 papers)
30% identity, 73% coverage of query (75.5 bits)
Build an alignment for WP_010966303.1 and 17 homologs with ≥ 30% identity
Or download the sequences
SUGPH_MYCTU / Q6MWZ7 Acid phosphatase; Broad-specificity phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.2; EC 3.1.3.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
27% identity, 93% coverage of query (73.6 bits)
YQGD_SCHPO / O94420 Probable phosphatase C1620.13; EC 3.1.3.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 84% coverage of query (71.2 bits)
YFFL_SCHPO / O94461 Probable phosphatase C1687.21; EC 3.1.3.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 94% coverage of query (71.2 bits)
PMGY_SCHPO / P36623 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
gpm1 / RF|NP_594889.1 monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1; EC 5.4.2.1 from Schizosaccharomyces pombe (see paper)
29% identity, 72% coverage of query (70.5 bits)
YO283_YEAST / Q12040 Broad-specificity phosphatase YOR283W; EC 3.1.3.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
28% identity, 91% coverage of query (67.8 bits)
1e59A / P62707 E.Coli cofactor-dependent phosphoglycerate mutase complexed with vanadate (see paper)
28% identity, 86% coverage of query (65.9 bits)
Gpm / b0755 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gpmA / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli (strain K12) (see 20 papers)
GPMA_ECOLI / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Escherichia coli (strain K12) (see 4 papers)
gpmA / PDB|1E58_A 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; EC 5.4.2.1 from Shigella flexneri (see 12 papers)
28% identity, 86% coverage of query (65.9 bits)
Q54NE6 2,3-bisphosphoglycerate 3-phosphatase (EC 3.1.3.80) from Dictyostelium discoideum (see paper)
27% identity, 75% coverage of query (63.5 bits)
GPM_THEAC / Q9HIJ2 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) (see paper)
28% identity, 89% coverage of query (62.0 bits)
F26_YEAST / P32604 Fructose-2,6-bisphosphatase; FBPase 2; EC 3.1.3.46 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
25% identity, 73% coverage of query (61.6 bits)
GPMA_MYCTU / P9WIC9 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
29% identity, 70% coverage of query (59.7 bits)
1k6mA / P16118 Crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (see paper)
27% identity, 73% coverage of query (57.4 bits)
5hr5A Bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2)
29% identity, 73% coverage of query (57.0 bits)
F262_BOVIN / P26285 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Bos taurus (Bovine) (see paper)
P26285 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Bos taurus (see 2 papers)
29% identity, 73% coverage of query (56.6 bits)
F261_RAT / P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
P07953 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see 4 papers)
28% identity, 73% coverage of query (55.8 bits)
PFKFB1 / P16118 Fructose-2,6-bisphosphatase (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 7 papers)
F261_HUMAN / P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
P16118 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 5 papers)
27% identity, 73% coverage of query (55.8 bits)
1tipA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
28% identity, 73% coverage of query (55.8 bits)
1c81A Michaelis complex of fructose-2,6-bisphosphatase
28% identity, 73% coverage of query (55.8 bits)
1c80A Regulatory complex of fructose-2,6-bisphosphatase
28% identity, 73% coverage of query (55.8 bits)
1c7zA Regulatory complex of fructose-2,6-bisphosphatase
28% identity, 73% coverage of query (55.8 bits)
1fbtA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
28% identity, 73% coverage of query (55.5 bits)
F26_ARATH / Q9MB58 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; 6PF-2-K/Fru-2,6-P2ase; AtF2KP; PFK/FBPase; EC 2.7.1.105; EC 3.1.3.46 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9MB58 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Arabidopsis thaliana (see 3 papers)
30% identity, 73% coverage of query (55.5 bits)
5htkA / O60825 Human heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2) (see paper)
28% identity, 73% coverage of query (55.5 bits)
PFKFB2 / O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 7 papers)
F262_HUMAN / O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
O60825 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 7 papers)
28% identity, 73% coverage of query (55.5 bits)
1bifA / P25114 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional enzyme complexed with atp-g-s and phosphate (see paper)
27% identity, 73% coverage of query (55.5 bits)
F264_RAT / P25114 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; 6PF-2-K/Fru-2,6-P2ase 4; PFK/FBPase 4; 6PF-2-K/Fru-2,6-P2ase testis-type isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
P25114 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see 3 papers)
27% identity, 73% coverage of query (53.9 bits)
6hvjA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 3
29% identity, 73% coverage of query (53.5 bits)
6etjA Human pfkfb3 in complex with kan0438241
29% identity, 73% coverage of query (53.5 bits)
2dwpA A pseudo substrate complex of 6-phosphofructo-2-kinase of pfkfb
29% identity, 73% coverage of query (53.5 bits)
6ic0A Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 4
29% identity, 73% coverage of query (53.5 bits)
6hviA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 2
29% identity, 73% coverage of query (53.5 bits)
5ajxA Human pfkfb3 in complex with an indole inhibitor 3
29% identity, 73% coverage of query (53.5 bits)
6ibyA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 6
29% identity, 73% coverage of query (53.5 bits)
6ibxA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 5
29% identity, 73% coverage of query (53.5 bits)
5ajzA Human pfkfb3 in complex with an indole inhibitor 5
29% identity, 73% coverage of query (53.5 bits)
5ajvB Human pfkfb3 in complex with an indole inhibitor 1
29% identity, 73% coverage of query (53.5 bits)
4ma4A S-glutathionylated pfkfb3
29% identity, 73% coverage of query (53.5 bits)
5ak0A Human pfkfb3 in complex with an indole inhibitor 6
29% identity, 73% coverage of query (53.5 bits)
4d4lA Human pfkfb3 in complex with a pyrrolopyrimidone compound
29% identity, 73% coverage of query (53.5 bits)
4d4jA Human pfkfb3 in complex with a pyrrolopyrimidone compound
29% identity, 73% coverage of query (53.5 bits)
5ajyA Human pfkfb3 in complex with an indole inhibitor 4
29% identity, 73% coverage of query (53.5 bits)
4d4mA Human pfkfb3 in complex with a pyrrolopyrimidone compound
29% identity, 73% coverage of query (53.5 bits)
3qpwA Pfkfb3 in complex with aluminum tetrafluoride
29% identity, 73% coverage of query (53.5 bits)
6ibzA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 7
29% identity, 73% coverage of query (53.5 bits)
6hvhA Human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 1
29% identity, 73% coverage of query (53.5 bits)
5ajwA Human pfkfb3 in complex with an indole inhibitor 2
29% identity, 73% coverage of query (53.5 bits)
4d4kA Human pfkfb3 in complex with a pyrrolopyrimidone compound
29% identity, 73% coverage of query (53.5 bits)
3qpuA Pfkfb3 in complex with ppi
29% identity, 73% coverage of query (53.5 bits)
2i1vB Crystal structure of pfkfb3 in complex with adp and fructose-2,6- bisphosphate
29% identity, 73% coverage of query (53.5 bits)
2dwoA Pfkfb3 in complex with adp and pep
29% identity, 73% coverage of query (53.5 bits)
2axnA / Q16875 Crystal structure of the human inducible form 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase (see paper)
29% identity, 73% coverage of query (53.5 bits)
PFKFB3 / Q16875 Fructose-2,6-bisphosphatase (EC 2.7.1.105; EC 3.1.3.46) from Homo sapiens (see 9 papers)
F263_HUMAN / Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 5 papers)
Q16875 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 21 papers)
29% identity, 73% coverage of query (53.1 bits)
2bifA 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase h256a mutant with f6p in phosphatase active site
26% identity, 73% coverage of query (51.6 bits)
Or start over
Lawrence Berkeley National Laboratory