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Searching for up to 100 curated homologs for WP_011023202.1 NCBI__GCF_000007345.1:WP_011023202.1 (324 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

mptN / Q58037 tetrahydrosarcinapterin synthase monomer (EC 6.3.2.33) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
MPTN_METJA / Q58037 Tetrahydromethanopterin:alpha-L-glutamate ligase; H(4)MPT:alpha-L-glutamate ligase; EC 6.3.2.33 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58037 tetrahydrosarcinapterin synthase (EC 6.3.2.33) from Methanocaldococcus jannaschii (see paper)
    37% identity, 80% coverage of query (154 bits)

Q5JFW0 lysyltransferase (EC 2.3.2.3); [amino group carrier protein]-L-2-aminoadipate ligase (EC 6.3.2.43); glutamate---[amino group carrier protein] ligase (EC 6.3.2.60) from Thermococcus kodakarensis (see paper)
5k2mG / Q5JFW0 Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa (see paper)
    34% identity, 78% coverage of query (111 bits)

5k2mI Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa
    34% identity, 78% coverage of query (111 bits)

Build an alignment

Build an alignment for WP_011023202.1 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

7qyrD / Q9HTZ2 Crystal structure of rimk from pseudomonas aeruginosa pao1 (see paper)
    29% identity, 98% coverage of query (108 bits)

LYSX_SACS2 / Q7SI95 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
    27% identity, 94% coverage of query (102 bits)

LYSX_SULAC / Q4JAP9 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4JAP9 [amino group carrier protein]-L-2-aminoadipate ligase (EC 6.3.2.43) from Sulfolobus acidocaldarius (see paper)
    26% identity, 95% coverage of query (91.3 bits)

ARGX_SULTO / Q970U6 Glutamate--LysW ligase ArgX; EC 6.3.2.- from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
3vpbB / Q970U6 Argx from sulfolobus tokodaii complexed with lysw/glu/adp/mg/zn/sulfate (see paper)
    29% identity, 72% coverage of query (90.5 bits)

4iwxA / P0C0U4 Rimk structure at 2.85a (see paper)
    28% identity, 98% coverage of query (89.4 bits)

Nek / b0852 ribosomal protein S6 modification protein from Escherichia coli K-12 substr. MG1655 (see 3 papers)
rimK / P0C0U4 ribosomal protein S6 modification protein from Escherichia coli (strain K12) (see 6 papers)
RIMK_ECOLI / P0C0U4 Ribosomal protein bS6--L-glutamate ligase; Polyglutamate synthase; Ribosomal protein bS6 modification protein; EC 6.3.2.- from Escherichia coli (strain K12) (see 2 papers)
    28% identity, 98% coverage of query (89.4 bits)

5zctH The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution.
    28% identity, 98% coverage of query (89.4 bits)

5zctA The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution.
    28% identity, 98% coverage of query (89.4 bits)

argX / Q4J8E7 glutamate--LysW ligase monomer (EC 6.3.2.60) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
ARGX_SULAC / Q4J8E7 Glutamate--LysW ligase ArgX; EC 6.3.2.- from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J8E7 glutamate---[amino group carrier protein] ligase (EC 6.3.2.60) from Sulfolobus acidocaldarius (see paper)
    27% identity, 72% coverage of query (85.1 bits)

7drpA / A6G4D7 Structure of atp-grasp ligase psnb complexed with phosphomimetic variant of minimal precursor, mg, and adp (see paper)
    23% identity, 92% coverage of query (53.5 bits)

7drnA Structure of atp-grasp ligase psnb complexed with precursor peptide psna2 and amppnp
    23% identity, 92% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory