Searching for up to 100 curated homologs for WP_011033217.1 NCBI__GCF_000007065.1:WP_011033217.1 (189 a.a.)
Found high-coverage hits (≥70%) to 47 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
7yc6A / Q58970 Crystal structure of d110p mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase
51% identity, 96% coverage of query (187 bits)
O59071 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Pyrococcus horikoshii (see paper)
53% identity, 97% coverage of query (186 bits)
GUA1 / P38625 GMP synthase monomer (EC 6.3.5.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GUAA_YEAST / P38625 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
39% identity, 94% coverage of query (121 bits)
1gpmA / P04079 Escherichia coli gmp synthetase complexed with amp and pyrophosphate (see paper)
35% identity, 96% coverage of query (121 bits)
GuaA / b2507 GMP synthetase (EC 6.3.5.2) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
guaA / P04079 GMP synthetase (EC 6.3.5.2) from Escherichia coli (strain K12) (see 15 papers)
GUAA_ECOLI / P04079 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; GMPS; Glutamine amidotransferase; EC 6.3.5.2 from Escherichia coli (strain K12) (see paper)
P04079 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Escherichia coli (see 3 papers)
guaA / GB|AAC75560.1 GMP synthase [glutamine-hydrolyzing]; EC 6.3.5.2 from Escherichia coli K12 (see 9 papers)
35% identity, 96% coverage of query (120 bits)
5tw7F / B4RJH7 Crystal structure of a gmp synthase (glutamine-hydrolyzing) from neisseria gonorrhoeae
36% identity, 98% coverage of query (115 bits)
GUAA_CRYNH / J9VUY6 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) (see paper)
38% identity, 96% coverage of query (114 bits)
2ywcA / Q5SI28 Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
36% identity, 96% coverage of query (113 bits)
GUAA_ASPFU / Q4WFT3 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
37% identity, 96% coverage of query (112 bits)
O85192 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Lacticaseibacillus rhamnosus (see paper)
35% identity, 96% coverage of query (110 bits)
GUAA_MYCTU / P9WMS7 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
39% identity, 94% coverage of query (109 bits)
GUA1 GMP synthase [glutamine-hydrolyzing]; EC 6.3.5.2 from Candida albicans (see 2 papers)
37% identity, 96% coverage of query (106 bits)
GUAA_SCHPO / Q9P772 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
36% identity, 96% coverage of query (104 bits)
GUAA_PLAF7 / Q8IJR9 GMP synthase [glutamine-hydrolyzing]; PfGMPS; Glutamine amidotransferase; Guanosine monophosphate synthetase; EC 6.3.5.2 from Plasmodium falciparum (isolate 3D7) (see 6 papers)
31% identity, 96% coverage of query (100 bits)
3uowA Crystal structure of pf10_0123, a gmp synthetase from plasmodium falciparum
31% identity, 96% coverage of query (100 bits)
GMPS / GI|6456564 GMP synthetase; EC 6.3.4.1 from Plasmodium falciparum (see paper)
31% identity, 96% coverage of query (98.6 bits)
4wioA / Q8IJR9 Crystal structure of the c89a gmp synthetase inactive mutant from plasmodium falciparum in complex with glutamine (see paper)
30% identity, 96% coverage of query (96.7 bits)
Build an alignment for WP_011033217.1 and 17 homologs with ≥ 30% identity
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8hx8A / F2RB79 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
29% identity, 98% coverage of query (93.6 bits)
papA / BAD21140.1 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae (see paper)
29% identity, 97% coverage of query (91.7 bits)
cmlB / F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
29% identity, 97% coverage of query (91.3 bits)
2vxoB / P49915 Human gmp synthetase in complex with xmp (see paper)
33% identity, 94% coverage of query (90.1 bits)
3uowB / Q8IJR9 Crystal structure of pf10_0123, a gmp synthetase from plasmodium falciparum
33% identity, 96% coverage of query (90.1 bits)
GUAA_MOUSE / Q3THK7 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Mus musculus (Mouse) (see paper)
33% identity, 94% coverage of query (89.0 bits)
GUAA_HUMAN / P49915 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Homo sapiens (Human) (see 2 papers)
P49915 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Homo sapiens (see paper)
32% identity, 94% coverage of query (88.6 bits)
GUAA_RAT / Q4V7C6 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Rattus norvegicus (Rat) (see paper)
32% identity, 94% coverage of query (88.6 bits)
trpG / BAC65123.1 anthranilate synthase component II from Burkholderia multivorans (see paper)
35% identity, 95% coverage of query (88.2 bits)
para-aminobenzoate synthase glutamine amidotransferase component II / b3360 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pabA / P00903 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 9 papers)
PABA_ECOLI / P00903 Aminodeoxychorismate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85 from Escherichia coli (strain K12) (see 3 papers)
P00903 aminodeoxychorismate synthase (EC 2.6.1.85); 2-amino-4-deoxychorismate synthase (EC 2.6.1.86) from Escherichia coli (see paper)
33% identity, 94% coverage of query (87.0 bits)
pabA / P28819 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) (EC 2.6.1.123) from Bacillus subtilis (strain 168) (see paper)
PABA_BACSU / P28819 Aminodeoxychorismate/anthranilate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85; EC 4.1.3.27 from Bacillus subtilis (strain 168) (see paper)
33% identity, 95% coverage of query (84.7 bits)
pabAB / P32483 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces griseus (see 5 papers)
ADCS_STRGR / P32483 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoic acid synthase; PABA synthase; EC 2.6.1.85 from Streptomyces griseus (see paper)
32% identity, 97% coverage of query (84.3 bits)
TRPG_AZOBR / P26922 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Azospirillum brasilense (see paper)
30% identity, 95% coverage of query (82.0 bits)
trpG / Q06129 anthranilate synthase β subunit (EC 4.1.3.27) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
TRPG_SACS2 / Q06129 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q06129 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Saccharolobus solfataricus (see paper)
32% identity, 94% coverage of query (79.0 bits)
trpG / P20576 anthranilate synthase β subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TRPG_PSEAE / P20576 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P20576 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
30% identity, 94% coverage of query (79.0 bits)
TRPG_PSEPU / P00901 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
31% identity, 95% coverage of query (78.2 bits)
trpG / AAD09117.1 anthranilate synthase component II from Rhodobacter sphaeroides (see paper)
28% identity, 95% coverage of query (71.6 bits)
ASB1_ARATH / Q42565 Anthranilate synthase beta subunit 1, chloroplastic; Anthranilate synthase component 2-1; Anthranilate synthase, glutamine amidotransferase component 2-1; Protein TRYPTOPHAN BIOSYNTHESIS 4; Protein WEAK ETHYLENE INSENSITIVE 7; EC 4.1.3.27 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
27% identity, 96% coverage of query (58.9 bits)
1ce8B Carbamoyl phosphate synthetase from escherichis coli with complexed with the allosteric ligand imp
29% identity, 90% coverage of query (57.8 bits)
CarA / b0032 carbamoyl phosphate synthetase subunit α (EC 6.3.5.5) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
carA / P0A6F1 carbamoyl-phosphate synthetase small subunit (EC 6.3.5.5) from Escherichia coli (strain K12) (see 10 papers)
CARA_ECOLI / P0A6F1 Carbamoyl phosphate synthase small chain; Carbamoyl phosphate synthetase glutamine chain; EC 6.3.5.5 from Escherichia coli (strain K12) (see 4 papers)
29% identity, 90% coverage of query (57.4 bits)
8hx9A / F2RB79 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
25% identity, 98% coverage of query (56.6 bits)
CPA1 / P07258 carbamoyl phosphate synthetase (EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
CARA_YEAST / P07258 Carbamoyl phosphate synthase arginine-specific small chain; CPS; CPSase; CPSase-arg; Arginine-specific carbamoyl phosphate synthetase, glutamine chain; Carbamoyl phosphate synthase A; CPS-A; Glutamine-dependent carbamoyl phosphate synthetase; EC 6.3.5.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
31% identity, 78% coverage of query (55.1 bits)
PYR1_MESAU / P08955 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster) (see 2 papers)
P08955 dihydroorotase (EC 3.5.2.3) from Mesocricetus auratus (see 2 papers)
30% identity, 76% coverage of query (54.3 bits)
1c3oB / P0A6F1 Crystal structure of the carbamoyl phosphate synthetase: small subunit mutant c269s with bound glutamine (see paper)
28% identity, 90% coverage of query (53.9 bits)
TRPG_SERMA / P00900 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Serratia marcescens (see paper)
29% identity, 92% coverage of query (52.4 bits)
PYR1_DROME / P05990 Multifunctional protein r; Protein rudimentary; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Drosophila melanogaster (Fruit fly) (see paper)
30% identity, 74% coverage of query (51.2 bits)
CARA_ARATH / Q9LVW7 Carbamoyl phosphate synthase small chain, chloroplastic; Carbamoyl phosphate synthetase glutamine chain; Protein VENOSA 6; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
26% identity, 80% coverage of query (50.4 bits)
1i7qB / P00900 Anthranilate synthase from s. Marcescens (see paper)
29% identity, 92% coverage of query (49.7 bits)
PYR1_SCHPO / Q09794 Multifunctional protein ura1; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
ura1 / RF|NP_593055.1 carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5.5 from Schizosaccharomyces pombe (see 3 papers)
26% identity, 95% coverage of query (45.1 bits)
CAD / P27708 CAD protein (EC 3.5.2.3; EC 6.3.5.5; EC 2.1.3.2) from Homo sapiens (see 6 papers)
PYR1_HUMAN / P27708 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human) (see 11 papers)
P27708 aspartate carbamoyltransferase (EC 2.1.3.2); dihydroorotase (EC 3.5.2.3); carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Homo sapiens (see 7 papers)
28% identity, 79% coverage of query (45.1 bits)
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Lawrence Berkeley National Laboratory