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Searching for up to 100 curated homologs for WP_011373501.1 NCBI__GCF_000012965.1:WP_011373501.1 (261 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PstB / b3725 phosphate ABC transporter ATP binding subunit (EC 7.3.2.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
PstB / P0AAH0 phosphate ABC transporter ATP binding subunit (EC 7.3.2.1) from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.7.1 / P0AAH0 Phosphate import ATP-binding protein PstB aka PhoT aka B3725, component of Phosphate porter, PhoSPstABC.  Serves as both a transporter and a sensor for transcriptional activation of the pho regulon in the presence of low external phosphate.  The unphosphorylated EIIANtr protein of the PTS (TC# 4.A) activates PhoR, the senor kinase that phosphorylates the response regulator, PhoB, that activates the pho regulon from Escherichia coli (see 6 papers)
pstB phosphate import ATP-binding protein pstB; EC 3.6.3.27 from Escherichia coli K12 (see 6 papers)
    56% identity, 95% coverage of query (310 bits)

P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
    56% identity, 95% coverage of query (310 bits)

pstB / OMNI|NTL02SP1895 phosphate ABC transporter, ATP-binding protein; EC 3.6.3.27 from Streptococcus pneumoniae R6 (see 2 papers)
    54% identity, 95% coverage of query (286 bits)

TC 3.A.1.7.5 / O51236 Phosphate import ATP-binding protein PstB, component of The phosphate transporter, PstABCS from Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
    54% identity, 95% coverage of query (283 bits)

TC 3.A.1.7.3 / C3KCB5 Putative ABC transporter ATP-binding protein, component of High-affinity phosphate-specific permease, PstAB/PhoS. The 3-d structure of PhoS = (PBP) = PfluDING) has been solved at high resolution by x-ray crystallography (Ahn et al. 2007) with phosphate bound (4F1U and 4F1V; 0.95Å resolution) and with arsenate bound (4F18 and 4F19; 0.88Å resolution) (Elias et al. 2012). Phosphate binds with 500-fold higher affinity than arsenate due to a dense and rigid network of ion-dipole interactions (Elias et al. 2012). The PBP from Halomonas sp from Pseudomonas fluorescens (strain SBW25)
    52% identity, 89% coverage of query (256 bits)

PSTB1_MYCTU / P9WQL1 Phosphate import ATP-binding protein PstB 1; ABC phosphate transporter 1; Phosphate-transporting ATPase 1; EC 7.3.2.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    54% identity, 89% coverage of query (251 bits)

TC 3.A.1.7.2 / P0C560 PstB, component of Phosphate transporter, PstSCAB from Mycobacterium smegmatis (see paper)
    52% identity, 96% coverage of query (248 bits)

PSTB2_MYCTU / P9WQK9 Phosphate import ATP-binding protein PstB 2; ABC phosphate transporter 2; Phosphate-transporting ATPase 2; EC 7.3.2.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    46% identity, 89% coverage of query (225 bits)

TC 3.A.1.3.14 / P39456 TcyC (YckI), component of Uptake system for L-cystine from Bacillus subtilis (see 7 papers)
    37% identity, 94% coverage of query (145 bits)

ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168) (see paper)
    35% identity, 93% coverage of query (144 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    34% identity, 93% coverage of query (137 bits)

TcyN / b1917 cystine ABC transporter ATP binding subunit (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
tcyN / P37774 cystine ABC transporter ATP binding subunit (EC 7.4.2.12) from Escherichia coli (strain K12) (see 7 papers)
TCYN_ECOLI / P37774 L-cystine transport system ATP-binding protein TcyN; EC 7.4.2.12 from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.3.10 / P37774 YECC aka CysZ aka B1917, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 5 papers)
    35% identity, 94% coverage of query (137 bits)

ANTRA_HALVD / D4GSY7 Probable anion import ATP-binding protein HVO_1886; EC 7.3.2.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    34% identity, 89% coverage of query (136 bits)

TCYN_BACSU / O34900 L-cystine import ATP-binding protein TcyN; EC 7.4.2.- from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.3.13 / O34900 TcyN (YtmN), component of Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine from Bacillus subtilis (see 4 papers)
    36% identity, 93% coverage of query (135 bits)

TC 3.A.1.139.1 / Q5Z8H2 Sensitive to aluminum rhizotoxicity 1, component of UDP-glucose exporter, STAR1/STAR2 (sensitive to aluminum rhizotoxicity) (Probable Type I topology) from Oryza sativa subsp. japonica
    37% identity, 82% coverage of query (135 bits)

STAR1_ORYSJ / Q0D9V6 Protein STAR1; ABC transporter ABCI.12; OsABCI12; ABC transporter I family member 12; Protein ALUMINUM SENSITIVE 1; Protein SENSITIVE TO ALUMINUM RHIZOTOXICITY 1 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
    37% identity, 82% coverage of query (135 bits)

TC 3.A.1.139.4 / Q9C9W0 ABC transporter I family member 17, component of Plasma membrane ABC exporter, sensitive to aluminum rhizotoxicity 1/2, STAR1/STAR2 (Larsen et al., 2005). Induced in response to aluminum exposure from Arabidopsis thaliana
    40% identity, 82% coverage of query (135 bits)

TC 3.A.1.10.2 / P74127 FutC aka SLL1878, component of Ferric iron (Fe3+) porter (see paper)
    33% identity, 94% coverage of query (133 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    33% identity, 96% coverage of query (132 bits)

TC 3.A.1.24.5 / Q9HT70 Methionine import ATP-binding protein MetN 2, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    34% identity, 93% coverage of query (132 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    33% identity, 96% coverage of query (132 bits)

2olkA Abc protein artp in complex with adp-beta-s
    33% identity, 96% coverage of query (132 bits)

2oljA Abc protein artp in complex with adp/mg2+
    33% identity, 96% coverage of query (132 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    35% identity, 91% coverage of query (126 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    36% identity, 82% coverage of query (125 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    36% identity, 82% coverage of query (125 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    35% identity, 91% coverage of query (125 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    35% identity, 91% coverage of query (125 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    35% identity, 91% coverage of query (124 bits)

7ahdC Opua (e190q) occluded
    37% identity, 79% coverage of query (124 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    35% identity, 87% coverage of query (124 bits)

7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
    32% identity, 91% coverage of query (112 bits)

4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
    32% identity, 91% coverage of query (112 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    32% identity, 95% coverage of query (112 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    32% identity, 95% coverage of query (112 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    32% identity, 95% coverage of query (112 bits)

ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; EC 7.6.2.- from Mus musculus (Mouse) (see 10 papers)
    30% identity, 91% coverage of query (112 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    32% identity, 86% coverage of query (112 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    31% identity, 94% coverage of query (111 bits)

ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; EC 7.6.2.- from Homo sapiens (Human) (see 9 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
    32% identity, 91% coverage of query (110 bits)

7qkrA / F2QQK6 Cryo-em structure of abc transporter ste6-2p from pichia pastoris with verapamil at 3.2 a resolution (see paper)
    32% identity, 85% coverage of query (109 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    33% identity, 86% coverage of query (109 bits)

8jwfA / Q7K6A5 Cryo-em structure of plasmodium falciparum multidrug resistance protein 1 with h1 helix in complex with mfq (see paper)
    35% identity, 83% coverage of query (108 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    30% identity, 89% coverage of query (108 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    30% identity, 89% coverage of query (108 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    30% identity, 89% coverage of query (108 bits)

8jwiA Cryo-em structure of the outward-facing plasmodium falciparum multidrug resistance protein 1
    34% identity, 83% coverage of query (107 bits)

4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
    33% identity, 87% coverage of query (107 bits)

8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
    31% identity, 87% coverage of query (106 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    31% identity, 86% coverage of query (106 bits)

Build an alignment

Build an alignment for WP_011373501.1 and 50 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
    29% identity, 95% coverage of query (106 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp-binding protein
    31% identity, 89% coverage of query (105 bits)

7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
    32% identity, 75% coverage of query (105 bits)

6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
    32% identity, 75% coverage of query (104 bits)

7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
    32% identity, 75% coverage of query (104 bits)

7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
    32% identity, 75% coverage of query (104 bits)

7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
    32% identity, 75% coverage of query (104 bits)

7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
    32% identity, 75% coverage of query (104 bits)

9ctgA Sapnp reconstituted human abcb1 bound to atp gammas
    32% identity, 75% coverage of query (104 bits)

4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
    31% identity, 90% coverage of query (104 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    30% identity, 87% coverage of query (104 bits)

6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
    31% identity, 90% coverage of query (104 bits)

3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    31% identity, 90% coverage of query (104 bits)

3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    31% identity, 90% coverage of query (104 bits)

4q9iA P-glycoprotein cocrystallised with qz-ala
    31% identity, 90% coverage of query (104 bits)

7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
    31% identity, 90% coverage of query (104 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    29% identity, 90% coverage of query (103 bits)

4xwkA P-glycoprotein co-crystallized with bde-100
    31% identity, 90% coverage of query (103 bits)

1g291 / Q9YGA6 Malk (see paper)
    30% identity, 89% coverage of query (103 bits)

6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
    32% identity, 75% coverage of query (103 bits)

MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
    33% identity, 75% coverage of query (103 bits)

6s7pA Nucleotide bound abcb4
    33% identity, 75% coverage of query (103 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    32% identity, 87% coverage of query (103 bits)

7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
    33% identity, 75% coverage of query (103 bits)

5koyA Mouse pgp 34 linker deleted bound with atp
    30% identity, 90% coverage of query (103 bits)

6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
    30% identity, 90% coverage of query (102 bits)

8wooA Structure of the wild-type arabidopsis abcb19 in the brassinolide and amp-pnp bound state
    29% identity, 90% coverage of query (102 bits)

8womA / Q9LJX0 Structure of the wild-type arabidopsis abcb19 in the brassinolide- bound state (see paper)
    29% identity, 90% coverage of query (102 bits)

8y5iA / P69874 Cryo-em structure of e.Coli spermidine transporter potd-potabc in translocation intermidiate state (see paper)
    32% identity, 87% coverage of query (102 bits)

8wp0A Structure of the arabidopsis e529q/e1174q abcb19 in the atp bound state
    29% identity, 90% coverage of query (100 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    28% identity, 90% coverage of query (100 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    28% identity, 90% coverage of query (100 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    28% identity, 90% coverage of query (100 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    28% identity, 90% coverage of query (100 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    28% identity, 90% coverage of query (100 bits)

4aywA Structure of the human mitochondrial abc transporter, abcb10 (plate form)
    31% identity, 89% coverage of query (100 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    28% identity, 90% coverage of query (99.8 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    28% identity, 90% coverage of query (99.8 bits)

TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
    31% identity, 89% coverage of query (99.8 bits)

7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
    30% identity, 90% coverage of query (99.4 bits)

7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
    30% identity, 90% coverage of query (99.4 bits)

7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
    30% identity, 90% coverage of query (99.4 bits)

7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
    30% identity, 90% coverage of query (99.4 bits)

6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
    30% identity, 90% coverage of query (98.6 bits)

ABCBB_HUMAN / O95342 Bile salt export pump; ATP-binding cassette sub-family B member 11; EC 7.6.2.- from Homo sapiens (Human) (see 21 papers)
TC 3.A.1.201.2 / O95342 Bile salt export pump, BSEP, ABCB11 or SPGP in the canalicular membrane of liver cells, is associated with progressive familial intrahepatic cholestasis-2 and benign recurrent intrahepatic cholestasis (Kagawa et al., 2008; Stindt et al. 2013; Park et al. 2016). It exports unconjugaged bile salts and glycine conjugates > taurine conjugates as well as the statin, pravastatin (Nigam 2015). BSEP mediates biliary excretion of bile acids from hepatocytes. Compounds based on GW4064 (Q96RI1), a representative farnesoid X receptor (RXR) agonist, enhance E297G BSEP transport activity from Homo sapiens (Human) (see 11 papers)
    28% identity, 90% coverage of query (97.8 bits)

8j5qD / P9WQJ5 Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
    30% identity, 92% coverage of query (97.4 bits)

7dv5U / O95342 Human bile salt exporter abcb11 in complex with taurocholate (see paper)
    28% identity, 90% coverage of query (97.4 bits)

8pmjA / O95342 Vanadate-trapped bsep in nanodiscs (see paper)
    28% identity, 90% coverage of query (97.4 bits)

7zdaC If(apo/asym) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
    30% identity, 93% coverage of query (97.4 bits)

HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    32% identity, 80% coverage of query (97.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory