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Searching for up to 100 curated homologs for WP_011383005.1 NCBI__GCF_000009985.1:WP_011383005.1 (132 a.a.)

Found high-coverage hits (≥70%) to 5 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PHS_DROME / O76454 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Drosophila melanogaster (Fruit fly) (see paper)
    54% identity, 73% coverage of query (122 bits)

PCBD2 / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 (EC 4.2.1.96) from Homo sapiens (see 3 papers)
PHS2_HUMAN / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Homo sapiens (Human) (see paper)
Q9H0N5 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
    53% identity, 70% coverage of query (117 bits)

PHS_CHICK / O73930 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; cDcoH; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Gallus gallus (Chicken) (see paper)
    53% identity, 73% coverage of query (116 bits)

Build an alignment

Build an alignment for WP_011383005.1 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q48G05 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Pseudomonas syringae (see paper)
    28% identity, 73% coverage of query (46.2 bits)

Q02I31 Putative pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Pseudomonas aeruginosa (strain UCBPP-PA14)
    28% identity, 72% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory